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Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_16 | Pages 13 - 13
1 Dec 2015
Unuk S Miksic NG Vogrin M
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Acute osteomyelitis and septic arthritis are uncommon diseases in childhood that affect previously healthy children. A high index of suspicion, early diagnosis, initiation of appropriate antibiotic treatment and surgical intervention are essential for a good outcome.

The aim of our study was to evaluate our approach, clinical signs and the outcome of the diseases.

We retrospectively analyzed clinical, laboratory and microbiologic data in children hospitalized for acute haematogenous osteomyelitis or septic arthritis at the Department of Orthopaedic surgery in a 10-year period (from 2003 to 2013). Follow-up of outpatients was continued for at least 1 year or until the full recovery.

Acute haematogenous osteomyelitis or septic arthritis were confirmed in 22 patients, 14/22 (64%) had osteomyelitis and 8/22 (36%) arthritis, 16/22 (73%) were boys. The mean patient age was 9,3 years (SD:3,5), the median of the hospitalization was 32 days (IQR:13 – 60 days).

In children with osteomyelitis 10/14 (72%) had affected lower limb and in 4/14 (28%) the spine was affected. Six (80%) children had septic arthritis of the knee, hip joint was affected in one child and sacroiliac joint in one as well. We obtained blood cultures in 19/22 (86%) patients, bone biopsy was performed in 14/22 (64%). All infections were monomycrobial, Staphylococcus aureus was the most common pathogen, as expected.

In one patient the cause of the osteomyelitis was Panton-Valentine leucocidin (PVL) producing S. aureus. The characterics are presented in Table 1. All affected children recovered completely.

We observed 22 cases of pediatric bone and joint infections in a 10-year period. The most common pathogen was Staphylococcus aureus, as expected, althogh in more than half of cases no pathogens were found. One child suffered from osteomielitis caused by S. aureus strain producing PVL. We observed higher proportion of spine invovelment than previously reported in the literature.