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Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 209 - 209
1 May 2011
Tabani S Nagai H Kay P
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Patients with a history of septic arthritis or tuberculosis (TB) of the hip frequently develop secondary osteoarthritis (OA). These patients present a challenge for having joint replacement because of abnormal bone development, the possibility of re-infection, soft tissue problems and their life-style (more active than patients with old age arthritis). We retrospectively review a decent group of 55 cases where one stage cemented total hip arthroplasty was performed with history of old hip infection by a team of surgeons at Wrightington Hospital, Lancashire, UK from 1970 to 2008. The purpose of this study is to find the survival analysis with revision (for infection) as the end stage. There are 33 females and 22 males aged from 25 to 75 yrs (mean 52 years). 21 patients had proven or probable tuberculous infection, 29 had the past history of old septic hip, and the remaining 5 had recent septic hip (i.e., less than 5 years). The patients are followed for between 1 to 23 years (mean 10 years). Pre-operatively, 25 patients had arthrodesis while 24 patients had moderate to severe secondary OA. 3 patients had dysplastic acetabulum, 2 patients had shallow acetabulum and 1 had Avascular Necrosis (AVN). In 33 cases, intra-operative tissue samples didn’t grow any organism, 2 samples grew Staphylococcus aureus, 2 samples grew Coagulase Negative Staphylococcus (CNS), 1 grew pseudomonas, samples were not sent in 9 cases, laboratory did not process the sample in 1 case and no documentation found in 3 cases. Cement with antibiotics was used in 45 patients (Gentamicin alone in 37 cases, Gentamicin and Vancomycin in 3 cases, Gentamicin, Fucidic Acid and Eryth-romycin in 2 patients, Gentamicin, Vacncomycin and Streptomycin in 1 patient, Gentamicin and Streptomycin in 1 case and Gentamicin, Vacncomycin and Amoxycillin in 1 patient). Mostly intravenous antibiotics (3 doses of Cefuroxime) were given, but in few cases with old TB, anti-tuberculous treatment was started pre-operatively and continued for 3 months post-op. In 16 patients either antibiotics were not given or not documented to be given. Failure happened in 2 cases of positive intra-op sample culture with Staphylococcus aureus, 1 patient with pre-op aspiration which showed pseudomonas and in 2 cases where tissue sample showed no growth. 8 patients had revision of at least one of the components for aseptic loosening. The 2 failed cases with positive culture with Staphylococcus aureus had post operative antibiotics and extra antibiotics in cement. Both cases had early wound healing issues.

Conclusion: We can conclude that total hip arthroplasty is safe in old cases of septic or tuberculous hips, provided appropriate antibiotic cover. We have some evidence that total hip replacement can be carried out in cases of recent infection of hip but level of evidence is not very great as we don’t have a large sample of such patients.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 601 - 602
1 Oct 2010
Haleem S El-Zebdeh M Kamalsekaran S Tabani S Yeung E
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Purpose: Pigmented Villonodular Synovitis (PVNS) is an uncommon presentation characterised by hyperplastic synovium, bloody effusions and bone erosions. Incompletely resected localised and diffuse lesions have a high recurrence rate. The management of recurrent lesions depends on the expertise of the surgeon and severity of the lesion. The imaging characteristics of PVNS and experience of British knee surgeons in managing these lesions is presented in our study.

Methods: A postal questionnaire was sent to 100 knee surgeons of the British Association of Surgeons of the Knee (BASK) with questions relating to their experience in managing localised and recurrent PVNS. The options included either arthroscopic or open synovectomy with or without radiotherapy, radical excision or referral.

Results: 74 responses were included in the study. 73 out of the total cohort of 74 surgeons (98.7%) had seen less than 5 presentations in their career.

Localised lesions were treated primarily by arthroscopic synovectomy [N=58(78.4%)] or open synovectomy [N=12(16.2%)] with radiotherapy being utilised in 4 lesions (5.4%).

For local recurrence the management was arthroscopic [N=26(35.1%)] and open [N= 19(25.7%)] synovectomy. Radiotherapy was used in 18 (24.3%) of patients with localised recurrence and 8 (10.8%) of were referred to specialist units.

Infiltrating lesions were treated with open synovectomy and radiotherapy [N=22(29.7%)] and 20 cases [27.02%] were referred to specialist units.

Imaging of PVNS and Conclusions: The role of imaging is invaluable in early diagnosis and treatment due to limited experience in managing such presentations. Routine radiography and Computerised Axial Tomography (CT scan) often demonstrate non-marginal pressure erosions with sclerotic margins as well as nodular soft tissue masses. Sonography shows non-specific focal or nodular synovial thickening with increased flow on colour doppler. Magnetic Resonance imaging characteristics of PVNS are nodular, synovial masses which are low signal on T1-weighted and T2-weighted imaging.