Poly-L-lactic acid (PLLA) is characterized by its biocompatibility and biodegradability, and is used clinically. In our hospital, we started to use PLLA screws instead of metallic or ceramic screws in the fixation of acetabular bone grafts in total hip arthroplasty (THA) in 1990, because there were concerns about the use of rigid and nonbioabsorble screws, which might contribute to the absorption of the grafted bone and induce metallosis or third-body wear when breakage of the screws occurs. The purpose of this study was to review a series of cemented THA for dysplasia, with structural autograft fixed with PLLA screws. We focused on the survival rate of the acetabular component and radiological change of the grafted bone–socket interface. This study included 104 consecutive cemented total hip arthroplasties (80 patients) performed between July 1990 and December 1995 in our hospital. All patients were followed over 10 years and reviewed retrospectively. The grafted bone trimmed from the excised femoral head was fixed rigidly with 1 or 2 PLLA screws (cancellous lag screws 6.5 mm in bore diameter and 4.1 mm in grove diameter) (Fixsorb; Takiron Co., Ltd., Osaka, Japan). X-ray photographs taken just after the primary operation showed an obscure but still visible radiolu-cent region corresponding to the inserted PLLA screws in many cases. However, X-ray photographs at the final follow-up showed an unclear radiolucent zone at the sites of the PLLA screws, and the osteosclerotic line surrounding the site where the radiolucent zone had been found was confirmed in only 4 cases. Bone union was confirmed radiologically at the grafted site in every case, and there were no cases of early collapse or extravasation of the grafted bone. No positive resorption of the grafted bone was observed in any case. Kaplan–Meier survivorship analysis of socket revision, radiological loosening of the socket, and the appearance of a radiolucent line >
1 mm in the graft–socket interface as the endpoints indicated survival rates of 99%, 97.1%, and 63.5% at 10 years, and 96.6%, 90.2%, and 56.1% at 15 years, respectively. The results of this study indicated that PLLA screws are safe and useful for the fixation of acetabular bone graft concomitant to cemented THA with a careful rehabilitation program. However, because of concern about the mechanical insufficiency of the PLLA screws for THA with an early weight-bearing rehabilitation program, we have used mechanically stronger and bioabsorbable screws made of forged composites of hydroxyapatite and PLLA since 2003.