Dual mobility significantly reduces the risk of prosthetic instability. This mechanical complication occurs when the prosthetic head moves out from the retentive polyethylene liner, such phenomenon called intra-prosthetic dislocation reports a ten-year incidence of 2% in the literature.

We prospectively analysed all intra-prosthetic dislocations having occurred since 1985 in our department in order to investigate patient- and implant-related risk factors.

91 intra-prosthetic dislocations occurred with NOVAE (SERF) cups in 85 patients of mean age 50.7 years. Intra-prosthetic dislocation occurred after a mean period of 8.8 years.

A PRO (SERF) stem was implanted in 56 cases and a PF (SERF) stem in 35. The stems were different from one another in their neck diameter and material: 13 mm titanium neck and 16 mm stainless steel neck respectively.

When taking both prosthetic features into account, no significant difference could be established regarding the time between implantation and dislocation.

Comparison between these two prosthetic features was performed by means of two continuous homogeneous series which included 240 patients implanted with PF stems and 382 patients with PRO stems. At a mean 15-year follow-up, the two series reported a non-statistically different intra-prosthetic dislocation rate of 4%.

In both series, young age and large diameter cups were considered predisposing factors for intra-prosthetic dislocation.

Therefore, unlike suggested by several authors, prosthetic neck material and diameter do not appear as the main predictors for intra-prosthetic dislocation which is highly promoted by patient-related features.

Purpose of the study: Biphasic macroporous phosphocalcium ceramics are used in routine surgery to fill bone defects. This type of material presents the characteristics of an ideal substitute: free of the adverse effects of grafts, biocompatibility, bioactivity, osteoconduction, osteointegration, reproducibility, availability in sufficient quantity. The purpose of our work was to evaluate the role of osteointegration on the resistance of two macroporous biphasic phosphocalcium ceramics routinely proposed on the French market. These two macroprous materials have a similar chemical composition but vary by the presence or not of interpores.

Material and methods: The experimental model involved the implantation of ceramic cylinders in a femoral cortical site in sheep, via the intermediary of conduction chambers with specific cortical entrances. The resistance to compression of the implanted samples an non implanted controls was measured using the same ISO norms.

Results: After two months implantation in a cortical site in the sheep, Eurocer200plus^® exhibited a significant 38% increase in resistance to compression while in the same conditions, Triosite^® exhibited a 41% decline in resistance. For ceramics with open porosity, the interpores acted like tunnels enabling rapid colonization for osteoforming cells and early formation of new bone reaching the centre of the substitute, and leading to increased material resistance. Cell colonization of a ceramic with closed porosity is, on the contrary, slowed by the partitions, while its dissolution by biological fluids within the micropores occurs in all materials; there results an imbalance between absorption and synthesis, leading to loss of mechanical resistance as a first phase of osteointegration.

Discussion: Open macroposity enables an improvement in the mechanical properties of a biphasic ceramic substitute due to more rapid osteointegration. In the future, material associated with osteoinduction cells or proteins should play an important role, together with changes in the architecture of the ceramic skeleton which should play a determining role in terms of physical and biological properties.