Increasing experiences in determining the indication for UKA and improvements in design and materials of the prosthesis led to better results. The AMC-Uniglide has an unconstrained mobile bearing with congruent area contact. This ensures complete freedom to rotate and slide upon one other with physiologic kinematic and low intrinsic stability Minimal-invasive technique 30 patients with minimal-invasive AMC-Uniglide implantation technique were compared with 30 conventional implanted AMC’s and 30 total knee replacements in regard to rehabilitation and accuracy of implantation. 361 AMC-Uniglides 361 consecutive patients were investigated after AMC-Uniglide implantation. The mean duration of follow-up was 5.5 (2.3–12.5) years. Patients were reviewed using the American Knee Society Rating System. The roent-geno graphic analyses were performed with the American Knee Society Evaluation System. The clinical results of the investigated patients demonstrate that the AMC-Uniglide is a successful concept with a safe anchorage of the prosthesis and a good durability of the mobile bearings. An advantage of minimal invasive technique with regard to a reduced time of rehabilitation was found. The accuracy of implantation was comparable between the conventional and the minimal-invasive technique