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The Bone & Joint Journal
Vol. 95-B, Issue 2 | Pages 244 - 249
1 Feb 2013
Puig-Verdié L Alentorn-Geli E González-Cuevas A Sorlí L Salvadó M Alier A Pelfort X Portillo ME Horcajada JP

The purpose of this study was to compare the diagnostic accuracy for the detection of infection between the culture of fluid obtained by sonication (SFC) and the culture of peri-implant tissues (PITC) in patients with early and delayed implant failure, and those with unsuspected and suspected septic failure. It was hypothesised that SFC increases the diagnostic accuracy for infection in delayed, but not early, implant failure, and in unsuspected septic failure. The diagnostic accuracy for infection of all consecutive implants (hardware or prostheses) that were removed for failure was compared between SFC and PITC. This prospective study included 317 patients with a mean age of 62.7 years (9 to 97). The sensitivity for detection of infection using SFC was higher than using PITC in an overall comparison (89.9% versus 67%, respectively; p < 0.001), in unsuspected septic failure (100% versus 48.5%, respectively; p < 0.001), and in delayed implant failure (88% versus 58%, respectively; p < 0.001). PITC sensitivity dropped significantly in unsuspected compared with suspected septic failure (p = 0.007), and in delayed compared with early failure (p = 0.013). There were no differences in specificity.

Sonication is mainly recommended when there is implant failure with no clear signs of infection and in patients with delayed implant failure. In early failure, SFC is not superior to PITC for the diagnosis of infection and, therefore, is not recommended as a routine diagnostic test in these patients.

Cite this article: Bone Joint J 2013;95-B:244–9.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 607 - 608
1 Oct 2010
Matamalas A Palou EC García A Horcajada J Martínez-Díaz S Pelfort X Puig L Salvadò M Sorli L
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Background: The presence of bacteria forming biofilms or prior antimicrobial use has been shown to reduce the sensitivity of the standard technique (PT cultures) in patients with infection of orthopedic implants. Culturing fluid resulting from sonication (FRS) of prosthesis could improve the microbiologic diagnosis.

Objective: To analyze the diagnostic validity of culturing FRS of different orthopedic implants and PT culture

Methods: Between Jan 2007 and Apr 2008, patients undergoing knee or hip prosthesis removal, and those with ostheosyntesis or spinal instrumentation removal, were prospectively included (44 hip prosthesis, 63 knee prosthesis, 91 osteosynthesis and 14 spinal instrumentations). 5 PT specimens were collected for culture. Removed implants were sonicated during 5 min. (40Hz). Both, PT and FRS, were inoculated in aerobic agar (Chocolate Polyvitex), anaerobic agar (Schaedler + 5% blood) and in thioglycolat, for 7 days. Positive culture cut-off was defined as growing of > 5 CFU. Clinical diagnosis of prosthetic-joint infection was made as commonly accepted. Previous antimicrobial therapy was assessed. Diagnostic validity was calculated for both culturing methods. Sensitivity of methods was compared by Chi-square test (SPSS 15.0).

Results: 212 cases were included. Diagnostic of infection was made in 17 hip prosthesis (THA), 20 knee prosthesis (TKA), 24 osteosynthesis (OS) and 6 spinal fusions (SI).

Tissue culture was positive in 9 THA, 11 TKA 18 OS and 4 SI. Sonication culture was positive in 14 THA, 18TKA, 23 Os and 6 SI.

Tissue culture: Sensibility: THA53%, TKA 55%, OS 75% and SI 66%. Specificity: THA 96%, TKA 100%, OS 96%, SI 100%

Sonications: Sensibility: THA 82%, TKA 90%, OS 95% and SI 100%. Specificity: THA 96%, TKA 100%, OS 92%, SI 100%

Statistical differences favoring sonication were found in sensitivity in knee arthroplasty and osteosynthesis implants. 6 patients received antibiotics for > 7 days before implant was removed. Sonication culture was positive in 4 of them whereas only one standard culture yielded positive.

Conclusions: FRS cultures are more sensitive than PT cultures. Sensitivity of the method depends on which device is evaluated. Sonication also improves sensitivity of culture after preoperative antimicrobial therapy.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 332 - 332
1 May 2006
Martínez S Pelfort X Tey M Monllau J
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Introduction and purpose: Fractures of the tibial plateau account for 1% of the total. Among them, 55–70% involve the lateral plateau with differences in separation and subsidence. Minimally invasive osteosynthesis under arthroscopic control increases the indications in these cases. Our purpose is to assess the long-term clinical and radiological outcomes.

Materials and methods: We carried out a retrospective analysis of the medium-term results of closed fractures of the tibial plateau treated with arthroscopic reduction and percutaneous fixation with cannulated screws. A series of 32 patients with displaced fractures of the tibial plateau underwent surgery between 1993 and 2004. We used the AO classification. We analysed the clinical, functional and radiological results.

Results: The mean follow-up was 6 years. We treated 12 type 41B1, 7 type 41B21, 5 type 41B22, 7 type 41B31 and 1 type 41B12. All the fractures were consolidated and 79.1% had anatomical reduction. External meniscal injuries that could be sutured were present In 11 cases (34.3%). Joint balance was complete in 24 knees. According to the Lysholm scale 23 had an excellent outcome and 9 good. One case presented infection of the surgical wound, which was resolved by surgical debridement and antibiotic therapy.

Conclusions: The results suggest that this is a good method for treating selected fractures of the tibial plateau.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 112 - 112
1 Mar 2006
Corrales M Melendo E Puig L Monllau J Pelfort X
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Introduction: Meniscal extrusion is defined as the situation in which the meniscus is partially or totally luxated from the tibial plateau. The aim of this work is to ascertain the prevalence of meniscal extrusion in non arthritic patients and to define those factors related to it. Special attention was given to the fact of anatomic variations in the menisci attachments.

Methods: The knee MRI of 100 patients that were operated on arthroscopically in our institution was prospectively studied. Seventy-two males and 28 females, average age of 36.6 years (range between 13 and 64), entered in the study. There were 43 right-knees and 57 left-knees. The average weight of the patients was 77 kg (range 44 to 135).

Results: With respect to the medial meniscus 68.9% of the cases showed some degree of extrusion, averaging at 28% of the meniscal size (ranging from 10% to 60%). In the case of the lateral meniscus extrusion averaging 15% (ranging from 10% to 40%) was seen in 18.8% of the cases.

In this series the posterior types of anterior medial meniscus insertion were the most frequently found (69.5%).

Medial meniscal extrusion was significatively correlated to the presence of a chondral lesion (p = 0.008) and to anterior medial meniscus insertion (p = 0.001). No statistical significant relationship to the rest of parameters studied was encountered. None of the parameters studied were related to lateral meniscus extrusion

Discusion: Meniscal extrusion is frequent in our series and, the hypothesis that those patients who have an anterior variant of the anterior horn insertion of the medial meniscus tend to show greater extrusion is confirmed.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 188 - 188
1 Mar 2006
Gelber P Reina F Monllau J Martinez S Pelfort X Caceres E
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Background: The Inferior Glenohumeral Ligament (IGHL) has a well known mechanical and propioceptive relevance in shoulder stability. The interrelation of the IGHL anatomical disposition and innervation has not actually been described. The studys purpose was to determine the IGHL innervation patterns and relate them to dislocation.

Material & methods: Forty-five embalmed and 16 fresh-frozen human cadaveric shoulders were studied. Massons Trichrome staining was used to detail the intra-ligamentous nerve fibre arrangements. Neural behaviour of the articular nerves was studied dynamically at the apprehension position and while anteroinferior dislocation of the shoulder joint was performed.

Results: The anatomy of the IGHL was clearly defined. However, in 7 out of 61 cases the anterior band was only a slight thickening of the ligament. It averaged 34 mm (range, 28 to 46 mm) in length. The posterior band was only seen in 40.98 % of the cases. The axillary nerve provided IGHL innervation in 95.08 % of the cases. We found two distinct innervation patterns originating in the axillary nerve. In Type 1 (29.5 % of the cases), one or two collaterals later diverged from the main trunk to enter the ligament. Type 2 (65.57%) showed innervation to the ligament provided by the posterior branch for three to four neural branches. In both cases, these branches enter the ligament near the glenoid rim and at 7 oclock position (right shoulder). The shortest distance to the glenohumeral capsule was noted at 5 oclock position. The radial nerve (Type 3 innervation pattern) provided IGHL innervation in 3.28 % (2 specimens). Microscopic analysis revealed wavy intraligamentous neural branches. The articular branches relaxed and separated from the capsule at external rotation and abduction and stayed intact after dislocation.

Conclusions: The current results showed the IGHL to have three different innervation patterns. The special neural anatomy of the IGHL suggested it was designed to avoiding denervation when dislocated. This might contribute to understand why the neural arch remains unaffected after most dislocations. To our knowledge this is the first work that clearly describes specimens in which the main innervation of the IGHL is provided by the radial nerve.

Knowledge of the neural anatomy of the shoulder will clearly help in avoiding its injury in surgical procedures.