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Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 75 - 75
1 Mar 2006
Ziegler J Witzleb W Neumeister V Guenther K
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Background: This study was undertaken to investigate the differences in the metal ion serum concentrations after implantation of a MetaSUL-THR and a Birmingham Hip Resurfacing in comparison to implant free subjects and to review the influence of factors, possibly influencing the wear behaviour of the articulation.

Methods: Serum levels of cobalt, chromium and molybdenum in 74 patients after primary implantation of a MetaSUL-THR and in 111 patients after BHR were compared with the levels found in 130 control subjects without implants. Serum ion concentration was determined by atomic absorption spectrophotometry. Furthermore, the correlation between serum ion concentration and in-situ time, implant size and cup inclination was studied.

Results: The chromium and cobalt concentrations of BHR-patients as well as the chromium concentration of bilateral MetaSUL-THR-patients, however, were significantly higher as the concentrations of patients with unilateral MetaSUL-THR and the control group. The molybdenum serum concentration was very similar in all investigated groups.

The chromium serum concentration in patients with unilateral MetaSUL-THR and in patients with BHR showed the highest level in the postoperative period from 7 to 12 months.

Analyses of the subgroups showed an association between higher cobalt serum levels and cup inclination greater than 50 in patients with unilateral MetaSUL-THR more than 12 months after implantation. A statistically significant negative correlation was detectable between implant size and chromium as well as cobalt serum concentration in BHR-patients studied more than 12 months after implantation.

Conclusions: Metal-on-metal bearings of large diameter result in a greater systemic exposure of cobalt, chromium and molybdenum ions than bearings of smaller diameter. It is not known to what extent the different levels are due to corrosion of the surfaces of the components or to the amount of wear particles produced.

The chromium concentrations were highest 7–12 months after operation, what may due to a running-in of the bearing like known from hip simulator studies.

Interestingly implant size and metal ion serum levels correlate negatively in the BHR-patients studied more than 12 months after implantation. That could be due to an existing fluid film lubrication in these bearings and may be caused by the thicker fluid film in bearings with greater radius.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 279 - 279
1 Mar 2004
Witzleb W Hanisch U Neumeister V Knecht A Schulze K
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Aims: Do the short term results, histopathological þndings and metal ion concentration predict a better outcome of modern metal-on-metal Hip Resurfacings (BHR) in comparison with historic metal-on-polyethylene Resurfacings? Methods: Comparison of 241 BHR arthroplasties with a follow up from 6 months to 4 years with long time results of 305 WHR; of 7 BHR and 3 MetaSUL capsule tissue histologyñs and chromium and cobalt serum concentrations of 67 BHR patients and 32 patients after MetaSUL THR implantation. Results: We achieved mean Harris Hip Scores of 90–92 in our BHR series with no radiological signs of aseptic loosening and a revision rate of 1.7% after approx. 18 months in opposition to 8% of the WHR after 2 years. The BHR capsule tissue showed wear particles in only 2 of 7 cases in opposition to MetaSUL joints, where in every case wear particles were detectable. We found no statistical difference in metal ion serum levels between BHR and Meta-SUL joints. Conclusions: In our opinion the cementless press þt cup, the low wear metal-on-metal bearing and the conservative implantation technique of the BHR at least fundamentally improves the known disadvantages of the historic Resurfacings which may predict better long term results.