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The Bone & Joint Journal
Vol. 101-B, Issue 3 | Pages 246 - 252
1 Mar 2019
Iwata E Scarborough M Bowden G McNally M Tanaka Y Athanasou NA

Aims

The aim of this study was to determine the diagnostic utility of histological analysis in spinal biopsies for spondylodiscitis (SD).

Patients and Methods

Clinical features, radiology, results of microbiology, histology, and laboratory investigations in 50 suspected SD patients were evaluated. In 29 patients, the final (i.e. treatment-based) diagnosis was pyogenic SD; in seven patients, the final diagnosis was mycobacterial SD. In pyogenic SD, the neutrophil polymorph (NP) infiltrate was scored semi-quantitatively by determining the mean number of NPs per (×400) high-power field (HPF).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVI | Pages 65 - 65
1 Jun 2012
Quah C Yeoman MS Cizinauskas A Cooper K König MA McNally D Boszczyk BM
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Introduction

Lumbar spondylolysis is a fatigue fracture of the pars interarticularis and correlates with Spina Bifida Oculta (SBO) in 67%.

Hpothesis

Load is normally transferred across the arch in axial rotation. Bifid arch results in increased strain across the isthmus of the loaded inferior articular process.