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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_13 | Pages 75 - 75
7 Aug 2023
Mackay N Bausch N McGoldrick N Krishnan H Shah F Smith N Thompson P Metcalfe A Spalding T
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Abstract

Background

Osteochondral allograft (OCA) transplantation is a clinically and cost-effective option for symptomatic cartilage defects. In 2017 we initiated a program for OCA transplantation for complex chondral and osteochondral defects as a UK tertiary referral centre.

Aim

To characterise the complications, re-operation rate, graft survivorship and clinical outcomes of knee OCA transplantation.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_12 | Pages 30 - 30
1 Dec 2022
McGoldrick N Cochran M Biniam B Bhullar R Beaulé P Kim P Gofton W Grammatopoulos G
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Short cementless femoral stems are increasingly popular as they allow for less dissection for insertion. Use of such stems with the anterior approach (AA) may be associated with considerable per-operative fracture risk. This study's primary aim was to evaluate whether patient-specific femoral- and pelvic- morphology and surgical technique, influence per-operative fracture risk. In doing so, we aimed to describe important anatomical thresholds alerting surgeons.

This is a single-center, multi-surgeon retrospective, case-control matched study. Of 1145 primary THAs with a short, cementless stem inserted via the AA, 39 periprosthetic fractures (3.4%) were identified. These were matched for factors known to increase fracture risk (age, gender, BMI, side, Dorr classification, stem offset and indication for surgery) with 78 THAs that did not sustain a fracture. Radiographic analysis was performed using validated software to measure femoral- (canal flare index [CFI], morphological cortical index [MCI], calcar-calcar ratio [CCR]) and pelvic- (Ilium-ischial ratio [IIR], ilium overhang, and ASIS to greater trochanter distance) morphologies and surgical technique (% canal fill). Multivariate and Receiver-Operator Curve (ROC) analysis was performed to identify predictors of fracture.

Femoral factors that differed included CFI (3.7±0.6 vs 2.9±0.4, p3.17 and II ratio>3 (OR:29.2 95%CI: 9.5–89.9, p<0.001).

Patient-specific anatomical parameters are important predictors of fracture-risk. When considering the use of short stems via the AA, careful radiographic analysis would help identify those at risk in order to consider alternative stem options.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_10 | Pages 25 - 25
1 Aug 2021
Adamczyk A Nessek H Kim P Feibel R McGoldrick N Beaulé P Grammatopoulos G
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Over 62,000 total hip arthroplasty (THA) cases are performed each year in Canada, with an estimated annual healthcare system cost of $1.4 billion and resulting in 4 billion tonnes of waste annually (6,600 tonnes per day). The aims of this study were 1) Assess satisfaction of current/standard set-up amongst different stakeholders. 2) Assess energy, economic and waste cost of current set up and apply lean methodology to improve efficiency 3. Design and test SLIM setup based on lean principles and its ability to be safely implemented into everyday practice.

A Needs Assessment Survey was circulated to OR nursing staff to assess the need for change in the current THA OR setup at an academic tertiary referral hospital. Through feedback, surgeon input, and careful analysis of current instrumentation, the “SLIM setup” was created. Standard instrument tray numbers for elective THA were reduced from 9 to 3 trays. Eighty patients were then randomised to either the standard or SLIM setup. Four staff arthroplasty surgeons each randomised 20 patients to either standard or SLIM setup. OR time, blood loss, 90-day complication rates, cost/case, instrument weight (kg/case), total waste in kg/case (non-recyclable), case set-up time, and number of times and number of extra trays required were compared between groups.

The majority of nursing staff demonstrated dissatisfaction with the current THA setup and felt current processes lacked efficiency. Use of the SLIM setup, was associated with the following savings in comparison to standard (Trays = −6 (720kg/case); Waste = −1.5 kg/case; Cost = − $560 ($50.00 × 6 trays + 10min saved × $26.00 /min OR setup time)). OR time, blood loss and 90-day complication rate were not statistically different (p >0.05); however, set up time was significantly shorter in comparison to standard. Extra instrumentation was opened in < 10% of cases.

A more minimalist approach to THA can be undertaken using the SLIM setup, potentially resulting in cost, energy and waste savings. Estimate savings of $560,000 and 1.65 tonnes reduction in waste per 1,000 THAs performed may be realised.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_10 | Pages 37 - 37
1 Aug 2021
Falsetto A Sanders E Weishorn J Gill H McGoldrick N Beaulé P Innmann M Merle C Grammatopoulos G
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This matched cohort study aims to (a) assess differences in spinopelvic characteristics of patients having sustained a dislocation following THA and a control THA group without dislocation; (b) identify spinopelvic characteristics associated with risk of dislocation and; (c) propose an algorithm to define the optimum cup orientation for minimizing dislocation risk.

Fifty patients with a history of THA dislocation (29 posterior-, 21 anterior dislocations) were matched for age, gender, body mass index, index diagnosis, and femoral head size with 100 controls. All patients were reviewed and underwent detailed quasi-static radiographic evaluations of the coronal- (offset; center-of-rotation; cup inclination/anteversion) and sagittal- reconstructions (pelvic tilt, pelvic incidence, lumbar lordosis, pelvic-femoral-angle, cup ante-inclination). The spinopelvic balance (PI-LL), combined sagittal index (CSI= Pelvic-femoral-angle + Cup Anteinclination) and Hip-User-Index were determined. sagittal index (CSI= Pelvic-femoral-angle + Cup Anteinclination) and Hip-User-Index were determined. Parameters were compared between the two groups (2-group analysis) and between controls and per direction of dislocation (3-group analysis).

There were marginal coronal differences between the groups. Sagittal parameters (lumbar-lordosis, pelvic-tilt, CSI, PI-LL and Hip-User-Index) differed significantly. PI-LL (>10°) and standing pelvic tilt (>18°) were the strongest predictors of dislocation risk (sensistivity:70%/specificity:70%). All hips with a standing CSI<195° dislocated posteriorly and all with CSI>260° dislocated anteriorly. A CSI between 200–245° was associated with significantly reduced risk of dislocation (OR:6; 95%CI:2.5–15.0; p<0.001). In patients with unbalanced and/or rigid lumbar spine, standing CSI of 215–245° was associated with significantly reduced dislocation risk (OR:10; 95%CI:3.2–29.8; p<0.001).

PI-LL and standing pelvic-tilt determined from pre-operative, standing, lateral spinopelvic radiograph can be useful screening tools, alerting surgeons of patients at increased dislocation risk. Measurement of the pelvic-femoral angle pre-operatively provides valuable information to determine the optimum, cup orientation associated with reduced dislocation risk by aiming for a standing CSI of 200–245°.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_10 | Pages 30 - 30
1 Jul 2014
McGoldrick N Butler J Sheehan S Dudeney S O'Toole G
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The purpose of this study is to present a series of soft tissue sarcomas requiring complex vascular reconstructions, and to describe their management and outcomes.

Soft tissue sarcomas are rare mesodermal malignancies accounting for approximately 1% of all cancers diagnosed annually. Sarcomas involving the pelvis and extremities are of particular interest to the orthopaedic surgeon. Tumours that encase and invade large calibre vascular structures present a major surgical challenge in terms of safety of excision with acceptability of surgical margins. Technical advances in the fields of both orthopaedic and vascular surgery have resulted in a trend towards limb salvage with vascular reconstruction in preference to amputation. Limb-salvage surgery is now feasible due to the variety of reconstructive options available to the surgeon. Nevertheless, surgery with concomitant vascular reconstruction is associated with higher rates of complications including infection and amputation. We present a case series of soft tissue sarcomas with vascular compromise, requiring resection and vascular reconstruction. We treated four patients (n = 4, three females, and one male) with soft tissue masses, which were found to involve local vascular structures. Histology revealed leiomyosarcoma (n = 2) and alveolar soft part sarcomas (n = 2). Both synthetic graft and autogenous graft (long saphenous vein) techniques were utilised. Arterial reconstruction was undertaken in all cases. Venous reconstruction was performed in one case. One patient required graft thrombectomy at one month post-operatively for thrombosis.

We present a series of complex tumour cases with concomitant vascular reconstructions drawn from our institution's experience as a national tertiary referral sarcoma service.