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Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 21 - 21
1 Jul 2014
Müller S Todorov A Majewski M
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Summary

We found an increased natural expression of the growth factors bFGF, BMP-12, VEGF, and TGF-b1 during tendon healing of rat Achilles tendons. External application of these growth factors improved the tendons failure load in the early healing phase.

Introduction

Tendon ruptures recover slowly and the healing of injuries can be devastating. Growth factors are known to influence tendon healing. However, only little is understood about growth factors in a healing tendon. Aim of this study was to investigate the influence of growth factors on tendon healing of rats following their natural expression.