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Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_16 | Pages 36 - 36
1 Dec 2015
Lepetsos P Stylianakis A Leonidou A Argyris D Anastasopoulos P Lelekis M Tsiridis E Macheras G
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In spite of its incidence decreasing to 1% nowadays, prosthesis-related infections remain a research, diagnostic, therapeutic and cost-related problem. Early diagnosis, selection of an appropriate surgical strategy, accurate identification of the responsible microorganisms and construction of an appropriate antibiotic regimen are essential elements of any management strategy. Our study aim was firstly to compare the diagnostic accuracy of conventional periprosthetic tissue culture and culture of fluid derived from vortexing and bath sonication of the explanted hardware and secondly to investigate the role of possible metabolic factors affecting the sensitivity of the sonication method.

We investigated 70 patients undergoing revision hip or knee arthroplasty because of loosening of the prostheses, at our institution, between October 2011 and November 2013. Patients’ medical history and demographic characteristics were recorded. We compared the culture of samples obtained by sonication of explanted hip and knee prostheses with conventional culture of periprosthetic tissue for the microbiological diagnosis of prosthetic-joint infection.

Infectious Diseases Society of America (IDSA) Guidelines were used for the definition of prosthetic-joint infection. Thirty-two patients had septic loosening and 38 aseptic loosening (48 hip prostheses and 22 knee prostheses). The sensitivity of sonication fluid culture was 81.25% and the sensitivity of conventional tissue cultures was 56.25% (p-value = 0.043). The sensitivity of the sonication method was statistically higher in obese, diabetic patients, with age above 60, in uncemented arthroplasties and in arthroplasties because of primary osteoarthritis (p-values < 0.05).

The sonication method represents a reliable test for the diagnosis of prosthetic – joint infections with a greater sensitivity than the conventional periprosthetic tissue cultures, especially in obese, diabetic patients, with age above 60, in uncemented arthroplasties and in arthroplasties because of primary osteoarthritis.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_18 | Pages 6 - 6
1 Apr 2013
Leonidou A Kiraly Z Gality H Apperley S Vanstone S Woods D
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In treating open long bone fractures our current policy includes early administration of intravenous antibiotics and surgery on a scheduled trauma list. We have reviewed our infection rates 6 years following the initiation of this policy. 220 fractures were studied. Our records included time of administration of antibiotics, time to theatre and seniority of surgeon. We identified cases of superficial or deep infection. Surgical debridement occurred within 6 hours of injury in 45% of cases and after 6 hours in 55%. Overall infection rates were 11% and 15.7% respectively. Intravenous antibiotics were administered within 3 hours of injury in 80% of cases and after 3 hours in 20% of cases. Overall infection rates were 14% and 12.5% respectively. Infection rates where the most senior surgeon present was a consultant were 9.5% compared to 16% with the consultant absent. Our results suggest that the change in policy may have contributed to an improvement of the deep infection rate to 4.3% from the previous figure of 8.5%, although this decrease was not statistically significant. Time to theatre has not adversely affected the infection rate, and presence of a senior surgeon may have improved infection rates, although both trends were not statistically significant.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 99 - 99
1 Jan 2013
Leonidou A Pagkalos J Lepetsos P Antonis K Flieger I Tsiridis E Leonidou O
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Introduction

Early identification and conservative management of paediatric Monteggia fractures has been shown to correlate with good results. Nevertheless, several authors advocate more aggressive management with open reduction and internal fixation (ORIF) for unstable fractures. We herein present the experience of a tertiary paediatric hospital in the management of Monteggia fractures.

Methods

41 patients with Monteggia fractures (26 male and 15 female) were admitted and treated over a period of 20 years (1989 to 2009). The age of the patients ranged between 3 and 14 years (mean 7.5 years). Based on the Bado Classification, 29 fractures were type I, 3 were type II, 8 type III and 1 fracture was classified as type IV. Out of the 41 patients, 32 were managed with manipulation under anaesthesia (MUA) and above elbow plaster, whereas 9 underwent open reduction and internal fixation (ORIF) of the ulna.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 109 - 109
1 Jan 2013
Pagkalos J Leonidou A Lepetsos P Antonis K Flieger I Tsiridis E Leonidou O
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Introduction

Lateral humeral condyle fractures account for 17% of the distal humeral condyle fractures. They affect children between 5 and 10 years of age. Recent reports advocate closed reduction and internal fixation for the less displaced fractures.

Methods

We retrospectively reviewed children treated with open reduction internal fixation of these fractures at a single institution over a period of 13 years. All cases of lateral humeral condyle fractures treated with ORIF were identified through the trauma register. Case notes and radiographs were retrieved. Fracture classification, mode of fixation, time to union, and clinical examination at latest follow up were reviewed.