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Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 285 - 285
1 May 2010
Matzaroglou C Kouzoudis D Lambiris E Kallivokas A Athanaselis E Panagiotopoulos E
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Introduction: The chevron osteotomy is an accepted method for the correction of mild and moderate hallux valgus and generally advocated for patients younger than the age of sixty years. In the current work the finite element analysis applied to calculate the stress (force per unit area) on different cuts in the metatarsal bone model of the first ray in the human foot.

Material and Methods: The cuts have the form of a simple angle with 90 degrees ‘modified chevron osteotomy’, 60 ‘typical chevron osteotomy’ 70, 50 and 30, openings correspondingly, and share a common corner C, which is at the centre of a circle that fits the head of the metatarsal. In order to calculate the maximum stresses on the cuts, the bone is assumed to be with a 150 angle to the floor, which is the angle that it takes during the push-off phase.

Results: The calculations show a considerable difference on the stress distribution on the differnt cuts. In particular in the ‘90 degrees cut’ the normal (to the cut) stress is much larger than the shear stress. The opposite is true for the 60 cut. Since shear stresses are the ones that cause material failure, it is predicted that the 90 cut will heal much faster than the 60 cut. The nodes along the cuts where the normal and the shear stress were calculated in different osteotomies.

Conclusion: The FEM analysis confirm our clinical results of this modified chevron osteotomy of 90 degrees. The osteotomy site is firmly secured, avoiding early displacement of the lateral fragment and give earlier fusion.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 285 - 286
1 May 2010
Matzaroglou C Saridis A Trousas D Syggelos S Kravvas A Maragos S Lambiris E
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Purpose: Our aim was to evaluate the use of Ilizarov external fixator for ankle arthrodesis in severe post-traumatic or other ankle arthritis.

Patients and Methods: In the period of 8 years, 19 patients underwent ankle arthrodesis with the Ilizarov external fixator for severe ankle arthritis. In four patients the indication for arthrodesis was infection following failed surgical management of tibia plafond fractures, four patients had failed prior ankle arthrodesis and the rest suffered severe ankle arthritis. Eleven patients were male, eight female, with a mean age of 52 years (range 30–71 years). Seven patients had deformities greater then 10°. All had painful stiff ankle joints and 12 patients had disorder of ankle joint anatomy with significant limp. Anterior approach to the ankle joint was preferred, associated with distal fibular osteotomy. Secondary gradual corrections of postoperative deformity and additional compression at the arthrodesis site were performed with the Ilizarov system by closed manipulation. Following frame removal the arthrodesis was immobilised in a cast for a mean of 4 weeks.

Results: The mean follow-up period was 3,9 years. A solid ankle arthrodesis was achieved in 18 of the 19 cases. Failure of solid arthrodesis was detected in one patient with insufficient arthroscopic removal of articular cartilage and internal fixation was performed. In one case with major pin tract infection at the distal talus ring distal expansion of the frame was required. According to the Mazur rating system in 12 patients the results were good, in 5 patients fair and in 2 patients poor.

Conclusion: The use of Ilizarov external fixator for ankle arthrodesis provides significant interfragmentary compression forces, allows early weight bearing and post-operative adjustment of alignment of arthrodesis. This method should be considered as the treatment of choice in ankle arthrodesis, especially in revision cases and in the cases with infection around of the ankle joint.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 135 - 135
1 Mar 2009
Syggelos S Megas P Kasimatis G Kouzelis A Lambiris E
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INTRODUCTION: Osteonecrosis of the femoral head usually affects young patients and is caused by disturbance of the femoral head’s blood supply. Bone subchondral necrosis eventually leads to articular incongruity and secondary arthritis of the hip joint.

AIM: To study the adequacy and outcome of tantalum rods implantation in patients with avascular necrosis of the femoral head (up to grade III, according to Ficat’s classification)

PATIENTS AND METHOD: 25 patients with 30 affected hips (5 with bilateral lesions) have been treated, the last 5 years, by tantalum rod implantation. The mean age was 37 years and the mean time of follow up 20 months (6–48), for 24 patients. In four hips we had type III lesions and in the rest type II.

RESULTS: The postoperative evaluation included radiological and clinical (Harris Hip Score – HHS) examination. All patients with type II osteonecrosis had a statistically significant increased HHS score, 6 months and 1 year after tantalum implanting. One patient, with a type III lesion, was subjected in total hip replacement because of disease’s progression, 1 year later. The two others had serious pain relief and improved range of hip motion.

DISCUSSION: Implantation of tantalum rods can be a method of choice in treatment of early stages of AVN of the femoral head. The implant achieves decompression, supports the subchondral plate of the necrotic areas and probably induces bone re-generation. Studies in more patients and with extended follow up time will be helpful for method’s evaluation.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 70 - 71
1 Mar 2009
Pneumaticos S Chatziioannou S Savvidou C Nikolaos V Zoumboulis P Lambiris E
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Introduction: Minimally invasive augmentation techniques of vertebral bodies have been widely used in the treatment of painful osteoporotic vertebral compression fractures (VBCFs). Kyphoplasty seems to achieve pain relief and improvement in quality of life. However, the effect of kyphoplasty on the height and the kyphotic deformity of the vertebrae is now yet clear. The present study reports our experience in kyphoplasty procedures for osteoporotic VBCF’s.

Materials and Methods: A total of 105 VBCF (45 thoracic and 60 lumbar vertebrae) in 56 patients (16 male, 40 female; mean age: 69 years, range 32–87 years) were treated with kyphoplasty between 2002–2005. All patients were preoperatively evaluated with radiographs, MRI and bone scintigraphy, and postoperatively immediately following the procedure and 6 months later with radiographs. Eight patients were treated within a week from their injury (new fractures). All patients completed the Oswestry Disability Index Questionnaire pre- and immediately post-operatively and at 6 months. The height of the treated vertebrae and the kyphotic deformity were measured before, after the kyphoplasty and at 6 months. All procedures were performed under general anaesthesia and fluoroscopy guidance.

Results: 54 patients were included in the study; 2 patients expired from causes unrelated to the procedure. All patients experienced pain relief following the procedure and the average Oswestry Disability Index score decreased from 76% preoperatively to 12.4% postoperatively (P< 0.001) and to 18.5% (P< 0.001) at 6 months. The observed mean height restoration at 6 months was 3mm (range 0–15mm) (P=NS) and the kyphotic deformity correction was 3.70 (0–120) (P=NS). In the new fractures the height restoration was 7.1mm and the kyphotic correction 7.80 (P=0.01). There were no cases of pulmonary embolism nor were any significant cement leakages noted.

Conclusion: The treatment of painful osteoporotic VBCFs with kyphoplasty is safe and reduces pain and disability. However, it does not lead to restoration of the vertebral height nor to correction of the kyphotic deformity, except in new fractures.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 37 - 38
1 Mar 2009
Syggelos S Lambiris E Skouteris G Athanaselis E Giannakopoulos A Sourgiadaki E Panagiotopoulos E
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INTRODUCTION: Cases of aseptic non-unions in patients with a femoral shaft fracture, who have initially been subjected to internal fixation by plating, are not rare. The aim of this retrospective, polycentric study was to evaluate intramedullary nailing as method of treatment of these patients.

MATERIALS AND METHODS: Thirty patients with aseptic femoral shaft non-union, after plating, were treated by reamed intramedullary nailing (IMN). The type of nailing was chosen according to the type of non-union. The mean follow-up time was 30 months and for statistical analysis, the student’s t-test was used.

RESULTS: All non-unions were healed in a mean time of 7.8 months (5–18) after nailing. The mean healing time after fracture was about 18.6 months (9–54). The healing times were irrelevant to whether the fracture was open or closed, the type non-union (atrophic or hypertrophic) and the type of fracture, according the AO classification. On the contrary, the delay from the initial plating to definitive treatment (IMN) affected the healing time and the final outcome, in a statistically significant way. Healing time was increased by 34.45% when the definitive operation was performed after between 8 and 16 months compared to the ones before the 8th month and by 72.28% if the IMN was delayed to between 16 and 24 months.

DISCUSSION: In conclusion IMN can be an ideal and cost effective method in treating patients with aseptic femoral non-union, after plating failure. This definitive operation should be performed as soon as the non-union is diagnosed in order to avoid unnecessary delay in fracture healing.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 155 - 155
1 Mar 2009
Panagopoulos A Tyllianakis M Deligianni D Pappas M Sourgiadaki E Mavrilas D Papadopoulos A Lambiris E
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Purpose: Little has been written about the size of bone defect that could be restored with one-stage lengthening over a reamed intramedullary nail. The aim of this study was to investigate the mechanical properties of the callus created at gaps of various sizes in sheep tibiae treated with reamed intramedullary nailing.

Material-Methods: Sixteen adult female sheep were divided into four main groups: a simple osteotomy group (group I) and three segmental defect groups (1, 2, and 3 cm gap; groups I to III). One intact left tibia from each group was also used as the non-osteotomized intact-control group (group V). In all cases the osteotomy was fixed with an interlocked Universal Humeral Nail after 7 mm reaming. The osteotomized site was closed in layers including the periosteum without additional bone grafting and the limb was protected with long soft cast for 5 weeks postoperatively. Healing of the osteotomies was evaluated after 16 weeks by biomechanical testing. The examined parameters were torsional stiffness, shear stress and angle of torsion at the time of fracture.

Results: Samples with a simple osteotomy or 1 cm gap were fractured distally to the callus zone, whereas samples with 2 and 3 cm gaps were fractured at the callus zone or at distal metaphysis. The regenerate bone obvious in the x-rays in the group of 1 cm and 2 cm gap had considerable mechanical properties. Torsional stiffness in these two groups was nearly similar and its value was about 60% of the stiffness of the simple osteotomy group. A gradually decreased stiffness was observed as the osteotomy gap increased. There was a decrease in maximum shear stress from simple osteotomy to osteotomy with a fracture gap of 3 cm. No significant differences were found among the angles of torsion at fracture for the various osteotomies or the intact bone. Our results showed that the group of 1 cm gap had the 65% of the shear stress at failure of the simple osteotomy group.

Conclusion: We believe that there is evidence indicating that intramedullary nailing would be a reasonable option when one-stage lengthening of a long bone of 1 or 2 cm is contemplated.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 141 - 141
1 Mar 2009
Matzaroglou C Sourgiadaki E Panagiotopoulos E Saridis A Megas P Kouzelis A Filos K Lambiris E
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Purpose: The purpose of this prospective investigation is to determine if soft tissue and intra-articular local anaesthetic injection with bupivacaine and adrenaline have beneficial post-operative effects in patients who had total knee replacement (TKR) for osteoarthritis.

Material and Methods: 97 patients were divided randomly into 2 groups. The mean age was 74.7 years. In control group I there were 17 men and 33 women with a mean age of 73.5 years, in group II 16 men and 31 women of mean age of 74.9 years. The patients who were allocated to control group I (n =50) had no intraarticular treatment. We used general anaesthesia in all these patients. The study group II of 47 patients had received intraoperative injection of 0.25% bupivacaine(8ml) with epinephrine (1ml – 1mg) with 2/3 injected into the soft tissues and 1/3 injected into the joint. Clinical parameters evaluated included pain, blood use and bleeding index (calculated by preoperative haemoglobin minus postoperative hemoglobin plus the number of units of packed red blood cells transfused) and range of motion (ROM) at discharge.

Results: Flexion at discharge was improved from 70 (60–90)° in the control group to 90 (80–120)° in study group II (p = 0.005), the difference between the two groups receiving different amounts of analgesics were statistically significant. Number of days until 90 degrees of flexion and until discharge was reduced in group II compared with the control group I (p = 0.003 and 0.002). Also and the blood loss decreased.

Conclusion: This simple method is effective in improving all the postoperative course of primary TKR and should be considered as a part of a perioperative patient treatment program.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 158 - 159
1 Mar 2006
Karabasi A Giannikas D Vandoros N Lambiris E
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Purpose: End results analysis of surgical treatment of posttraumatic bone defects in the lower extremity by Ilizarov method and intramedullary nailing augmentation during consolidation.

Materials and method: Between 1990–2000,83 patients with posttraumatic bone defect (femur 26, tibia 57) with an average age of 38 years (11–65y.) were surgically treated. Open fracture was the cause of bone defect in 50 patients (60%). In the rest 33 (40%) patients, the bone defect was the result of a surgical removal of a nonviable bone due to osteomyelitis or infected non-union. The average length of bone defect was 8,5 cm. (4–20 cm.). In all cases corticotomy and application of Ilizarov device was necessary to initiate bone transport. In 26 patients the Ilizarov device was removed during consolidation and interlocking intramedullary nailing was performed. Selection criteria for changing method were: 1) delayed union at the docking site (13 pt.), 2) Intolerance of the Ilizarov device (6 pt.), 3) Angular deformity > 10 degrees (7 pt.). Radiological and clinical assessment was performed periodically. Functional recovery and bone healing were evaluated according to A.S.A.M.I criteria.

Results: Forty-eight patients (58%) presented delayed union at the docking site. In 35 patients compression- distraction was necessary to promote union. The rest 13 patients were healed using an interlocking intramedullary nailing. Three refractures needed reapplication of the Ilizarov device. Angular deformity of more than 10 degrees was found in 13 patients. Seven of them needed an osteotomy and intramedullary nailing. All bone defects were finally covered and solid bone formation resulted.

Conclusions: The Ilizarov method offers unique advantages in treatment of bone defects. The use of an interlocking intramedullary nail during consolidation, is a treatment option for delayed docking site union and prolonged treatment time.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 81 - 81
1 Mar 2006
Karabasi A Giannikas D Saridis A Vandoros N Lambiris E
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Purpose: A clinical retrospective study of surgical treatment of chronic posttraumatic osteomyelitis by the Ilizarov method was conducted by analyzing the end results.The aim was to evaluate the efficacy of distraction osteogenesis in covering large bone defects and eradicate infection.

Materials and method: Between 1990–2000, twenty-one patients with chronic osteomyelitis were surgically treated. Inclusion criteria were: 1) active infection of more than six months and 2) bone defect (after the surgical debridement was completed) > 4cm.The average length of bone defect was 9,5 cm. (4–28cm.). In all cases corticotomy and application of the Ilizarov device was necessary to initiate bone transport.The protocol of the Association for the Study and Application of the Method of Ilizarov (A.S.A.M.I), was used to evaluate the results. All patients were examined clinically and radiographically in order to assess the proper alignment, the progress of bone healing and possible signs of infection.

Result: Thirteen patients (62%) presented delayed union at the docking site. In 4 patients compression –distraction was necessary to promote union. In 9 patients (43%) the Ilizarov device was removed and interlocked intramedullary nailing was performed after eradication of the infection was confirmed by clinical and laboratory data. Recurrence of infection occurred in one patient. Elimination of infection and solid bone formation was the end result for all patients. Two refractures at the docking site needed reapplication of an Ilizarov device. In one case angular deformity of more than 10 degrees needed correctional osteotomy.

Conclusions: The Ilizarov method addresses successfully infection, bone defect, deformity, and leg length discrepancy simultaneously. All these may coexist in difficult cases of chronic osteomyelitis. Complications associated specifically with bone transport in exceeded bone defects ,after radical resection of infected bone, include certainly delayed union or non-union at the docking site and prolonged treatment time.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 188 - 188
1 Mar 2006
Dimakopoulos P Giannikas D Pappas M Papadopoulos A Lambiris E
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Aim: End result study of closed intramedullary nailing of humerus fractures.

Materials & methods: Between 1995–2003, 42 patients with fracture of the humeral shaft, were selected to be treated by I.N. The average age was 48 years old (17years–82years) The Selection criteria were: α) loss of closed reduction (24 patients), b) pathological fractures (5 patients), c) non-union following external fixation (2 patients) and d) delay of union (7 patients). The intramedullary nail was inserted through a proximal entry point via a transdeltoid incision. In 25 cases the entry point was below the greater tuberosity to avoid rotator cuff injury and in 18 cases the entry point was intraarticular. All nails were locked either proximal (41) or distally (1). Open technique was required for 21 cases. Passive full range of motion of elbow and shoulder joint was encouraged after the second postoperative day. Active assisted exercises were initiated the second postoperative week. Bone healing was confirmed by clinical and radiological findings. Shoulder mobility was evaluated by the Constant-Murley scoring system.

Results: The average follow-up time was 21 months (9 months–8 years).All fractures were finally healed. The average healing time was 13 weeks (8weeks–13weeks). Patients with extraarticular entry point of the nail had full passive shoulder motion between the 2th and the 4th postoperative week, whereas patients with intraarticular nail application presented delayed passive shoulder motion with final limitation of the normal range of motion. Seven patients had painful shoulder motion 3 months postoperatively. There were 4 patients with neurapraxia of the radial nerve installed posttraumatic, who had full recovery 3 months later. There was one proximal migrated nail, which required revision. None of the patients required nail removal.

Conclusions: Intramedullary nailing of humeral shaft fractures seems to be a reliable method of treatment. Shoulder mobilization after anterograde insertion of the nail can be easily restored with proper choice of entry point and proper physiotherapy program. The advantages of this method include: shorter operative time, less blood loss, small incision with minimal soft tissue damage. Extraarticular nail insertion should be the entry point of choice as there is no trauma to the rotator cuff.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 37 - 37
1 Mar 2006
Tyllianakis M Giannikas D Panagopoulos A Lambiris E
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Purpose: The retrospective evaluation of long-term results after reconstructive radial osteotomy for mal-united distal radius fractures.

Material-Method: Twenty-eight patients (21 male and 7 female, average aged 46 years) with 23 dorsal and 5 palmar angulated malunited distal radius fractures were operatively treated during 1994–2002 in our department. The main indications were pain and functional impairment. Dorsal or palmar approach was used in proportion to the site of angulation. The preoperative average radial inclination, radial length and volar or dorsal tilt were 13.5 degrees, 6.3 mm and 23.5 degrees respectively. An open wedge radial osteotomy followed by interposition of trapezoidal iliac crest bone graft and fixation with plate ands crews was performed in all patients four months at least after the initial surgery. An ulnar leveling procedure was considered necessary in 2 patients.

Results: All patients were available in the last follow up evaluation (mean 3.7 years). The functional result according to Mayo wrist score was rated as very good in 15 patients, good in 7 and poor in 6. The average improvement in radial inclination was 14 degrees, in radial length 6.5 mm and in volar or dorsal tilt 21 degrees. The complication rate was 22.7%, including 2 material failures, 1 extensor pollicis longus rupture, 1 nonunion and 3 recurrences of the deformity.

Conclusion: Surgical reconstruction for malunion is technically demanding and may not completely restore the anatomy. Patient satisfaction, however, in terms of increased function, decreased pain and decreased deformity is sufficient high to warrant reconstructive treatment.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 20 - 20
1 Mar 2006
Matzaroglou C Panagiotopoulos E Chanos M Papoutsakis M Lambiris E
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Purpose: The evaluation of midterm results of a proposed surgical technique for the correction of hallux valgus deformity.

Material-Methods: Fifty-one female patients with sixty-two hallux valgus deformities were operatively treated between 1997–2002. The average age was 54.9 years and the mean follow up period was 32.7 months. A modified – 90 degrees angled – chevron osteotomy fixed with a Hebert screw was performed in all patients. Concomitant lesser toes abnormalities were managed at the same time. Preoperative, postoperative and last follow up radiographic intermetatarsal (IMA) and hallux valgus (HVA) angles, were measured and compared. Subjective analysis consisting of the AOFAS hallux scale was performed.

Results: The averaged preoperative HVA was 34.1 (range 22–56) and the averaged IMA 15.5 (range 10–29). The corresponding postoperative angles were 14.2 (range 0–28) and 8.1 (range 6–22). The mean AOFAS score was 94.3 (65–100). All the osteotomies were fused and there was not any case of non-union or loosening. Two patients showed late recurrence of the deformity but refused any further treatment.

Conclusions: Hebert screw is a reliable fixation method of the chevron osteotomy for the treatment of hallux valgus. The osteotomy site is firmly secured, avoiding early displacement of the lateral fragment.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 159 - 159
1 Mar 2006
Matzaroglou C Saridis A Panagiotopoulos E Vandoros N Lambiris E
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Purpose: The purpose of this study was to evaluate the results of 23 patients with septic nonunion of the distal tibial metaphysis type Pilon fractures treated with Ilizarov technique.

Material and Methods: Between 1990 and 2002 the Ilizarov technique was used in 23 patients with posttraumatic infected nonunion of the distal tibia. Seventeen were males and 6 females. Average age was 40.1 years (range16–68 years). Mean duration of nonunion was 13,8 months and the average number of failed previous surgical procedures 2.2.

According to AO classification there were 3 non-unions with quiescent infection and no drainage, 4 with active infection and no drainage, and 16 with infection and drainage. The ankle joint was ankylosed in 6 patients preoperatively and it was painful in all patients. Thirteen patients had an angular deformity of more than 7 degrees (range 7–30 degrees, mean 16 degrees). Sixteen patients had a mean bone defect of 2.5 cm (range 1 to 6 cm). Monofocal or bifocal compression-distraction osteogenesis technique with or without bridging the ankle joint was performed in all cases. Ankle arthrodesis was necessary in 4 cases. Mean external fixation time was 139.6 days and mean follow-up period was 4 years.

Results: The results were evaluated using the functional and radiological scoring system described by Paley. The results were excellent in 7 patients (30.4%) good in 9 (39.1%) fair in 5 (21.7%) and 2 (8.69%) poor while the functional results were excellent in 4 patients (17.39%) good in 8 (34,8%), fair in 7 (30,4%) and poor in 4 (17,39%). Bone union and eradication of infection were achieved in all cases. Four bone defects required bone grafting and freshening at the docking site. Ankle motion was difficult to record preoperatively but good to very good ankle function was obtained at final follow up evaluation in 12 patients.

Conclusions: The Ilizarov technique is a reliable method in the treatment of metaphyseal septic nonunion of the distal tibia particularly in cases with angular deformity, ankle joint contracture and bone defects. Compliance of the patient is absolutely necessary.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 31 - 31
1 Mar 2006
Athanasiou V Papachristou D Saridis A Scopa C Lambiris E Megas P
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Aims: This experiment study was undertaken to evaluate the differences, in bone response to various grafts.

Methods: Ninety, 3.5 months New Zeland white rabbits, weighing 4kg, were divided randomly in 6 groups of 15 animals. Under anesthesia, a 4.5mm hole was drilled in the 2 posteriors femoral condyles of each rabbit, in totaling 180 condyles. Holes were filled with various grafts as follow: Group I-autograft, Group II-xenograft (Lubboc®), Group III-allograft DBM (Grafton®), Group IV-substitute calcium sulfate (Osteoset®), Group V-substitute calcium phosphate hydroxyapatite (Ceraform®), Group VI- was used control. After the implantation, the animals were sacrificed at 1, 3 and 6 months intervals tissue samples from the implanted areas were processed for histological evaluation.

Results: Group I: At 1 month, autologous grafts were lined with activated osteoblasts and osteoclasts. Lamellar bone and cartilage were evident. Neoangiogenesis was prominent. At 3, 6 months defects were filled with mature bone. Group II: Lubboc® displayed moderate (1 month) to intense (3 months) remodeling activity and pronounced neoangiogenesis. At 3 months, endochondral osteogenesis and lamellar bone production were more prominent. At 6 months graft material was significantly restricted and lamellar had considerably replaced woven bone. Group III: Grafton® putty was present at 1, 3 months. There were few osteoblasts and numerous multinuclaeated cells rimming implant surfaces. Endochondral ossification foci, new bone formation and neovascularisation were observed (1, 3 months). At 6 months DBM fibers were absent. Lamellar and woven bone was evident. Group IV: At 1 month new bone (mostly woven) was present, lined with activated osteoblast and few osteoclasts. Endochondral ossification and angiogenesis were evident. At 3, 6 months bone remodeling was augmented, and Osteoset® graft was diminished. Complete closure of defects was observed, at 6 months. Group V: Ceraform® exhibited almost the same properties as Osteoset®. However, endochondral osteopoiesis and bone remodeling were less intense. Additionally, after 6 months, Ceraform® was still evident. Group VI: The defect areas were clearly observed at 1, 3 months.

Conclusion: Autografts are the most effective graft materials. Although Lubboc® is not totally resorbed, it seems to induce lamellar bone synthesis stronger than Grafton®. Bone substitutes are inferior to allografts.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 2 | Pages 232 - 237
1 Feb 2006
Saridis A Panagiotopoulos E Tyllianakis M Matzaroglou C Vandoros N Lambiris E

We reviewed 13 patients with infected nonunion of the distal femur and bone loss, who had been treated by radical surgical debridement and the application of an Ilizarov external fixator. All had severely restricted movement of the knee and a mean of 3.1 previous operations. The mean length of the bony defect was 8.3 cm and no patient was able to bear weight.

The mean external fixation time was 309.8 days. According to Paley’s grading system, eight patients had an excellent clinical and radiological result and seven excellent and good functional results. Bony union, the ability to bear weight fully, and resolution of the infection were achieved in all the patients. The external fixation time was increased when the definitive treatment started six months or more after the initial trauma, the patient had been subjected to more than four previous operations and the initial operation had been open reduction and internal fixation.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 273 - 274
1 Mar 2004
Papadopoulos A Tyllianakis M Karageorgos A Sourgiadaki E Papachristou D Chrisanthopoulou A Lambiris E
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Aims: To evaluate the effectiveness of external fixation exchange by intramedullary nailing during consolidation phase following callus distraction phase. Methods: In 12 skeletally mature female sheep, equally divided in two groups (group A and group B), we performed tibial shaft osteotomy and 2cm gradual callus distraction using Ilizarov external fixator in a 0,5mm/12h rate. In group A, Ilizarov fixator was removed immediately after lengthening completion, and static unreamed intramedullary nail was inserted. In group B, Ilizarov device remained during consolidation phase. Formatted callus was studied, with radiographs, ultrasonograms, and triplex. All animals were sacrificed 70 days after osteotomy and bone specimens, were evaluated by DEXA and histopathologic examination. Results: In group A, all animals successfully tolerated intramedullary nailing and limb alignment was attained. All but one formatted mature callus and had started the remodeling phase retaining callus length, before being sacrificed. One animal had delayed callus maturation and 0,5cm loss of callus length, because of failed insertion of distal locking screw in the nail. In group B, all formatted mature callus too, but 2 had serious axis disorder, 3 persistent superficial pin-track infections and 1 deep infection in the same time. Conclusions: Replacement of Ilizarov device by static unreamed intramedullary nail during callus consolidation phase decreases the total duration of external fixation, limits joint stiffness, pin-track infections and axial deformities, and provides protection against refracture. Our results suggest that there is no considerable difference between callus maturation in the two groups.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 320 - 320
1 Mar 2004
Panagiotis Z Kaisidis A Megas P Papoutsakis M Lambiris E
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Aims: To investigate the potential of biological þxation of cementless total hip prosthesis in patients over 75 years old, with diagnosed osteoporosis. Methods: Between 1994Ð2000, 30 patients (mean age 77.3 years) underwent total hip arthroplasty (THA). Twenty-two (22) patients, 10 male and 12 female, were found at the last follow-up, which ranged from 1.5–7 years (mean follow-up, 3 years). THA was performed due to primary osteoarthritis (n=16), subcapital fracture (n=4), or dysplastic hip (n=2). Eight (8) smooth, tapered design (CLS) and 14 proximally porous coated prostheses were implanted. Singh index was used for the evaluation of osteoporosis and modiþed Harris Hip Score was used for the clinical evaluation of each patient. Modiþed Wixon score was used for the evaluation of stability probability of the tapered stem. Engh score was calculated for the evaluation of osseointe-gration of the porous coated implants. Results: Pre and post-operative mean Singh index was grade 4. Mean modiþed Harris Hip Score at the last follow-up was 88.6. For the CLS-Spotorno stem a stable þxation probability was calculated at 74.8%, while possible instability was calculated at 48.17%. Porous coated stems provided +13.45 mean Engh score, implying satisfactory þxation of the implant. Post-operative systematic complications are not reported, in contrast to 3 dislocations in the þrst post-operative period, which were treated by closed reduction. Conclusions: In patients over 75 years old, with possible cardiopulmonary disease, cementless total hip arthroplasty offers a reliable treatment, regardless the presence of osteoporosis. Satisfactory osseointegration and absence of systematic complications is compromised by the high cost of titanium implants.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 244 - 244
1 Mar 2004
Aristotelis K Megas P Zouboulis P Vassilakos P Lambiris E
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Aims: To evaluate the value of 99mTc-labeled mono-clonal Fab antibodies (Leukoscan) in the diagnosis of septic loosening of total hip arthroplasty (THA). Methods: 16 patients (mean age 63.2 years) with hip arthroplasty (5 hemi,9 cementless,2 cemented THAs) were investigated for deep infection with the use of Leukoscan. Patient selection was based on a “high-risk protocol”. All patients were clinically evaluated using modified HHS and each patient’s workout included x-rays, WBC, ESR, CRP, dynamic bone scan 99mTc-MDP and Leukoscan. Two (2) patients were treated by wide debridement and continuous lavage,6 with revision surgery and 8 with Girdlestone. Histologic samples and cultures were received and their results were compared with Leukoscan’s findings. Results: Preoperative evaluation of the patients revealed as major risk factors:pathologic blood tests (16), previous surgical interventions (13), implant loosening (8), wound infection (7). Mean mHHS was 58 (28–80), mean ESR 51 (23–87 mm/h), mean CRP 4,1 (0,9–18 mg/dl). Bone scans were evaluated as 15 positive and 1 negative and they were matched with 15 positive and 1 negative Leukoscan respectively. Twelve (12) positive histopathologic results and 2 positive tissue cultures were matched with 14 positive Leukoscans, while 1 positive Leukoscan was not verified by positive histopathologic findings of chronic infection. Bacteriae identified were: S.epidermidis 5x, S.aureus 2x, Escherichia Coli 1x, S.saprophyticus 1x, Klebsiella pneumoniae 1x. Conclusions: Leukoscan seems to offer a reliable diagnostic tool for investigation of septic bone infection in presence of hip arthroplasty, presenting a senstitivity of 100% and spesitivity of 93,75%. Proper patient selection, based on diagnostic criteria and risk factors is essential.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 316 - 316
1 Mar 2004
Lambiris E Megas P Athanasiou V Triandafillopoulos P
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Aims: To investigate the effect of tibial reamed intramedullary nailing in treating tibial shaft aseptic nonunion. Method: Between 1990 to 2002, the intramedullary nailing was used in100 patients with aseptic tibial nonunion. Seventy-þve were men and 25 women with a mean age of 31 years (ranging from 18 to 76 years). Thirty-eight (38%) of the fractures were initially open (A:9, B:12, C:15) according to Gustilo-Anderson classiþcation. Sixty-seven (67%) cases were initially treated with external þxation, 13 (13%) with plate and screws, 6 (6%) with I.N., and 14 (14%)with plaster of Paris. The time that elapsed from injury to intramedullary nailing ranged from 6 months to 7 years (mean 15,6 months). Fibular osteotomy was performed in 76 cases through a separate incision. In 6 cases bone grafts from the iliac crest were used. Results: During a follow-up period of one to seven years (mean: 2 years), all of the cases achieved consolidation an average of 6 months after nailing. In 4 cases a late infection was observed which settled after nail removal. One patient developed impending compartment syndrome which was detected on the þrst post-operative day and was treated with a fasciotomy. Transient peroneal nerve palsy occurred in one patient and this recovered in 3 months. In nine patients a clinically acceptable deformity was noticed. Conclusions: Because of its high union rate and low complication rate, we believe that the reamed nailing technique should be considered preferentially for all aseptic tibial shaft nonunion cases.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 330 - 330
1 Mar 2004
Panagiotis M Athanasiou V Kargados A Lambiris E
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Aims: Outcome of the distal tibial fractures treated with interlocking nail. Method: We reviewed 108 patients with distal tibial fractures which were treated in our clinic between 1990 using interlocking intramedullary nailing. 94 patients (63 men and 31 women) were found in the recent follow up. AO fracture classiþcation system was used Seventy-eight patients had concomitant fractures of the lateral malleolar and 4 had medial malleolar fractures. Eight (8,5%) of the fractures were open grade I. All fractures were managed with closed reamed nailing. In fourteen cases the nail had to be shortened. The lateral malleolar fractures were þxed before tibial nailing to ensure overall alignment. Results: Union was achieved in 89 (94,6%) fractures with a mean time of union of 4,2 months (range:3–10 months). One deep infection (1,06%) lead to nonunion. Three aseptic cases had delay union which required nail dynamization. In one more nonunion case bone grafting and þbulectomy required. Postoperative transient peroneal palsy occurred in 2 (2,12%) patients which were fully recovered. One patient developed deep posterior compartment syndrome leading to FHL conctracture, needed tendon lengthening. Conclusions: Interlocking intramedullary nailing is a reliable, safe and effective method of managing distal tibial fractures with or without minimal ankle joint involvement.