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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_6 | Pages 37 - 37
1 May 2019
Windell L Haque A Kulkarni A Alabort E Barba D Reed R Singh H
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Background

Periprosthetic femoral fractures following total hip arthroplasty are relatively uncommon but are associated with significant morbidity. With an increasing number of total hip arthroplasties being carried out in an aging population we need to ensure correct implants are chosen for our patients. A recent review of NJR data suggested a significantly higher revision risk for the Zimmer CPT stems due to periprosthetic fractures when compared to the Stryker Exeter stems.

Objectives

Our aim was to compare the biomechanics of periprosthetic fractures around the CPT and Exeter V40 stems in a composite saw bone model to identify if a difference in fracture risk exists between the two stems. We also compared the engineering design of the two implants in order to analyse the possible effect this may have on fracture risk.


The Bone & Joint Journal
Vol. 98-B, Issue 10 | Pages 1347 - 1354
1 Oct 2016
Palan J Smith MC Gregg P Mellon S Kulkarni A Tucker K Blom AW Murray DW Pandit H

Aims

Periprosthetic fracture (PF) after primary total hip arthroplasty (THA) is an uncommon but potentially devastating complication. This study aims to investigate the influence of cemented stem designs on the risk of needing a revision for a PF.

Patients and Methods

We analysed data on 257 202 primary THAs with cemented stems and 390 linked first revisions for PF recorded in the National Joint Registry (NJR) of England, Wales and Northern Ireland to determine if a cemented femoral stem brand was associated with the risk of having revision for a PF after primary THA. All cemented femoral stem brands with more than 10 000 primary operations recorded in the NJR were identified. The four most commonly used cemented femoral stems were the Exeter V40 (n = 146 409), CPT (n = 24 300), C-Stem (n = 15 113) and Charnley (n = 20 182).

We compared the revision risk ratios due to PF amongst the stems using a Poisson regression model adjusting for patient factors. Compared with the Exeter V40, the age, gender and ASA grade adjusted revision rate ratio was 3.89 for the cemented CPT stem (95% confidence interval (CI) 3.07 to 4.93), 0.89 for the C-Stem (95% CI 0.57 to 1.41) and 0.41 for the Charnley stem (95% CI 0.24 to 0.70).


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 212 - 212
1 Jan 2013
Malviya A Kulkarni A Reed M
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Since its introduction in 2007 the UKITE exam has been an annual event in the diary of Orthopaedic trainees. It aims to simulate the written FRCS (T&O) examination style and offers trainees practice, immediate feedback and an update of the progress they have made through their training. It also allows bench marking against their peers nationally. The editorial process has been overhauled to allow online editing of questions throughout the year, and this has streamlined the question selection process.

The fifth edition of UKITE was held in December 2011. 669 trainees and 35 non-trainees sat for the examination. Consistently over the five years of UKITE we have seen a similar distribution of results showing improving performance until the final year (64.5% for 2011) and a drop in the performance in the last year (56.6% for 2011). Overall 80% of the trainees felt the exam was fair and better than last year. 80% of the trainees who had sat FRCS (T&O) previously thought that the UKITE 2011 was similar in difficulty. 98% trainees want to sit it again and 95% thought there was educational value in sitting the exam. Over 93% were satisfied with central and local provisions made for the exam. Some examining centres in NHS hospitals faced server failure issues and provision was made to sit for their trainees to sit un-invigilated from home. The mean score for the invigilated examination (53.6%) was significantly (p< 0.001) lower than that of un-invigilated examination (63.6%).

UKITE continues to evolve and has become a regular feature in the post-graduate orthopaedic calendar. It is perceived as a useful way of revising and maintaining a core level of knowledge as part of the exam preparation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 201 - 201
1 Sep 2012
Malviya A Kulkarni A Reed M
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Since its introduction in 2007 the UKITE exam has been an annual event in the diary of Orthopaedic trainees. It aims to simulate the written FRCS (T&O) examination style and offers trainees practice, immediate feedback and an update of the progress they have made through their training. It also allows bench marking against their peers nationally.

UKITE 2010 has made further progress and for the first time trainees from all the deaneries in UK participated. A total of 645 trainees appeared for the examination that was held in December 2010. We introduced remote access from home for trainees (N=171, 26.5%) who could not appear in an “examination centre”. An online editorial process was also introduced, which made the work of the question editing team easier.

The scores ranged from 25.5 to 93.4% with a mean of 54.2% (sd=11.8). The score consistently improved from ST1 (41.8%) to ST7 (64.3%) level and then declined at ST8 (54.7%) level. The mean score for candidates sitting at home (53.3%, sd=11.4) was similar (p=0.23) to those sitting at an invigilated examination venue (54.6%, sd=11.9). The extreme low and high scores were more frequent invigilated exam. The feedback suggested that 95% trainees felt that UKITE has educational benefit and 98% wish to sit again. 75% want it as an annual self-assessment tool. 80% feel that it was better than last year and of those who had sat FRCS (T&O) nearly 80% felt it was very similar.

UKITE continues to evolve and has become a regular feature in the post-graduate orthopaedic calendar. It is perceived as a useful way of revising and maintaining a core level of knowledge as part of the exam preparation.


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 9 | Pages 1170 - 1175
1 Sep 2012
Palan J Roberts V Bloch B Kulkarni A Bhowal B Dias J

The use of journal clubs and, more recently, case-based discussions in order to stimulate debate among orthopaedic surgeons lies at the heart of orthopaedic training and education. A virtual learning environment can be used as a platform to host virtual journal clubs and case-based discussions. This has many advantages in the current climate of constrained time and diminishing trainee and consultant participation in such activities. The virtual environment model opens up participation and improves access to journal clubs and case-based discussions, provides reusable educational content, establishes an electronic record of participation for individuals, makes use of multimedia material (including clinical imaging and photographs) for discussion, and finally, allows participants to link case-based discussions with relevant papers in the journal club.

The Leicester experience highlights the many advantages and some of the potential difficulties in setting up such a virtual system and provides useful guidance for those considering such a system in their own training programme. As a result of the virtual learning environment, trainee participation has increased and there is a trend for increased consultant input in the virtual journal club and case-based discussions.

It is likely that the use of virtual environments will expand to encompass newer technological approaches to personal learning and professional development.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXII | Pages 73 - 73
1 May 2012
Kulkarni A Ramaskandhan J Pagnamenta F Siddique M
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Introduction

Ankle replacement is a major surgery with significant soft tissue dissection and bleeding. The skin quality is often poor in these patients due to age, edema, venous congestion, arteriopathy or previous procedures and soft tissue injury. The chances of wound infection increase with delayed wound healing. Absorbent non-adherent dressing (ABD) and VAC dressing applied in theatre after ankle replacement were assessed in a cohort of 147 patients with wound complications, pain, satisfaction and length of stay as outcome measures.

Patients and methods

71 consecutive patients were treated with ABD post-operatively after ankle replacement. The practice was then changed to VAC dressings for 76 consecutive patients. 44 patients had additional procedures performed with ankle replacement (11 from ABD group and 33 from VAC group). Retrospective analysis of prospectively collected data was performed. All patients had daily pain score, wound status, hospital stay, satisfaction and range of movement recorded.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXII | Pages 31 - 31
1 May 2012
Kulkarni A Soomro T Siddique M
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TMTJ fusion is performed for arthritis or painful deformity. K-wire and trans-articular screws are usually used to stabilize the joints. We present our experience with LP for TMTJ fusion in first 100 joints.

Patients and methods

100 TMTJ in 74 patients were fused and stabilised with LP between January 2007 and December 2010. The indication was Lisfranc arthritis and hallux valgus. Iliac crest bone autograft was used in 64 joints. Auto graft was used in 22/53 first TMT fusions. All patients post-operatively had below knee plaster immobilization and protected weight bearing walking for first 6 weeks. Clinical and radiological surveillance continued until bone. AOFAS midfoot scale was used as outcome measure.

Results

There were 18 male and 56 female patients with average age of 51 (14 -68). AOFAS midfoot scale improved 42% for pain, 30% for function and 53% for alignment. Average AOFAS overall score improved from 30 pre-op to 67 post op.

95 joints had clinical and radiological fusion. 1 patient needed removal of metalwork and 3 had delayed wound healing and 4 had radiological non- . All non- s were in 1st TMTJ where bone graft failed and were revised. None of the lesser ray TMTJ had non- . Average satisfaction score was 7 out of 10. 86% said they would recommend it to a friend and 91% would have it again.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 13 - 13
1 Mar 2012
Kulkarni A Jameson S James P Woodcock S Reed M
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Background

Total Knee Replacement (TKR) is technically demanding, time consuming and has higher complication rates in super obese (BMI>45) patients. Bariatric surgery can be considered for such patients prior to TKR although its effect on complications is unknown.

Methods

All patients who underwent bariatric surgery and a TKR in the NHS in England between 2005 and 2009 were included. Hospital episode statistics data in the form of OPCS, ICD10 codes were used to establish 90-day DVT, PE and mortality rates (inpatient and outpatient). In addition, readmission to orthopaedics, joint revision and ‘return to theatre for infection’ rates were also established. Code strings for each patient were examined in detail to ensure the correct gastric procedures were selected. Fifty-three patients underwent bariatric surgery then TKR (44-1274 days) (group 1). Thirty-one patients underwent TKR then bariatric surgery (33-1398 days) (group 2).


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 483 - 483
1 Nov 2011
Kulkarni A Soomro T Siddique M
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Introduction: Tarsometatarsal joint (TMTJ) fusion is performed for arthritis or painful deformity. First TMTJ fusion may be performed as a part of corrective surgery for hallux valgus deformity. K-wires and trans-articular screws are often used to stabilize the joints. We present our experience with the use of locking plates (LP) for TMTJ fusion.

Patients and Methods: Thirty-three TMTJ’s in 19 patients were fused and stabilised with LP’s between January and September 2008. The procedure was performed for Lisfranc arthritis in 13 patients and Lapidus procedures in six. Two out of 6 were revisions after failed fusion using transarticular screws. Iliac crest bone autograft was used in 26 joints in 12 patients. All patients post-operatively had below knee plaster immobilization and protected weight bearing walking for first 6 weeks. Clinical and radiological surveillance continued until bone union. AOFAS midfoot scale was used as outcome measure.

Results: There were 7 male and 12 female patients with average age of 51 (14–68). The American orthopaedic foot and ankle surgery society (AOFAS) midfoot score showed a 42% improvement in pain, 30% improvement in function and 53% improvement in alignment. The average AOFAS overall score improved from 30 preoperativley to 67 postoperativley. All except one joint in one patient had clinically and radiologically fused joints. One patient underwent removal of the metalwork and four had delayed wound healing. The average satisfaction score was 7 out of 10. 86% said of patients said that they would recommend the surgery to a friend, and 91% would undergo the surgery again.

Discussion: Locking plates have been recently introduced for ankle and foot surgery. Biomechanical studies have shown that the plates are not as strong or stiff as trans-articular screw fixation, however, they are easy to use, have more flexibility for realignment and can act as a buttress for bone graft. In our series all, except one, patients achieved bony union without loss of alignment.

Conclusion: Locking plates provide satisfactory stability for TMTJ fusion, without complications.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 296 - 296
1 Jul 2011
Kulkarni A Partington P Reed M
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Introduction: Following successful introduction in 2007, all training programs except two across the UK participated in the examination in 2008. The examination was run along the principles of curriculum based, online delivery with immediate results and providing supportive information for the questions. It remains free of charge as long as the trainee had contributed questions. The project is supported by an educational grant from Depuy, a Johnson and Johnson Company.

Material and Methods: In 2008 trainees from various regions were appointed to a UKITE review board, which creating good quality questions with supportive information. We took on board the feedback from 2007 examination and improved the quality of questions. Some questions from the 2008 examination were reported as ambiguous. The review board met and ambiguous questions were deleted from the exam and scores were recalculated.

Results: 648 trainees took UKITE 2008. The average scores increased up to 5th year SpR and dropped in year 6. Central organisation (86%) and local organisation (90%) were acceptable. 95% felt the examination pages were easy to use. There was difficulty in accessing the examination from NHS networks in some centers on the final day. 95% found there was educational benefit and 99% would like to sit again in 2009.

In the feedback from UKITE 2008, 85% of trainees felt it was better quality than 2007. The trainees wanted more questions on clinical situations. Those approaching the FRCS examination are interested in using the database towards preparation for the real examination. Some enthusiastic trainees would like the facility to submit questions early. We aim to improve on these in 2009.

In 2009 we also aim to open the examination for other surgical specialties and international trainees through elogbook.org.

Conclusion: UKITE has made progress in 2008. We aim to improve it further in 2009.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 312 - 312
1 Jul 2011
Kulkarni A Soomro T Siddique M
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Introduction: TMTJ fusion is performed for arthritis or painful deformity. First TMTJ fusion may be performed for Hallux valgus deformity. K-wire and trans-articular screws are usually used to stabilize the joints. We present our audit of experience with LP for TMTJ fusion.

Patients and Methods: 33 TMTJ in 19 patients were fused and stabilised using LP between January and September 2008. The procedure was performed for Lisfranc arthritis in 13 and Lapidus procedure in 6. Two out of 6 were revisions after failed fusion using transarticular screws. Iliac crest bone autograft was used in 26 joints in 12 patients. All patients post-operatively had below knee plaster immobilization and protected weight bearing walking for first 6 weeks. Clinical and radiological surveillance continued until bone union. AOFAS mid-foot scale was also used as an outcome measure.

Results: There were 7 male and 12 female patients with average age of 51 (14–68). AOFAS midfoot scale showed 42% improvement in pain, 30% improvement in function and 53% improvement in alignment. Average total AOFAS score improved from 30 preoperative to 67 postoperative.

All except 1 joint in one patient had clinical and radiological fusion of their joints. 1 patient needed removal of metalwork and 4 had delayed wound healing. Average satisfaction score was 7/10. 86% Patients would recommend it to a friend and 91% would have it again.

Discussion: Locking plates have been recently introduced for ankle and foot surgery. Biomechanical studies have shown plates are not as strong or stiff as trans-articular screw fixation however they are easy to use, have more flexibility for realignment and can act as a buttress for bone graft. In our review all patients except one had bone union without loss of alignment.

Conclusion: TMTJ fusion improves pain and function. Locking plates provide satisfactory stability for TMTJ fusion


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 21 - 21
1 Jan 2011
Kulkarni A Jameson S Partington P Reed M
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The first United Kingdom In-training Examination (UKITE) was held in 19 training programmes during December 2007. The aims of the project are to offer a national, online examination (providing immediate results to trainees) and to allow practice for the ‘real’ FRCS T& O examination with similarly formatted questions based on the UK T& O curriculum. All Speciality training years (StR2, StR3 and above, and all SpRs) and all deaneries will participate in the future. A total of 450 trainees sat this first examination. This is an online exam (accessed through the eLogbook/OCAP website) which is voluntary and has no bearing on RITA outcomes. To take part in the exam trainees were asked to provide 3 questions for a bank which can be used in subsequent years for both UKITE and the FRCS T& O examination.

The exam was 3 hours and questions were of multi-choice (MCQ) and extended matching question (EMQ) style covering all aspects of orthopaedics. Correct answers and explanations were available to the trainee after their answer had been submitted. Final scores ranged from 35% to 92%. Mean scores increased from 48% (StR2) to 73% in SpR year 5 (StR7 equivalent). This was followed by a drop off in performance in the final year of training. Three candidates had equal top scores at 92%. 97% stated they would sit the UKITE again and 93% felt there was educational benefit. The length and level of difficulty of the exam was felt to be satisfactory. Improvements were suggested for question quality. The UKITE is a powerful tool for self-assessment of trainees. This analysis establishes a baseline for future years.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 57 - 57
1 Jan 2011
Kulkarni A Cloke D Partington P Reed M
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Introduction: Following successful introduction in 2007, all training programs except two participated in 2008. The examination was run along the principles of curriculum based, online delivery with immediate results and providing supportive information for the questions. The examination remains free of charge for the trainees and is supported by an educational grant from Depuy.

Material and methods: In 2008 a UKITE review board was appointed to create good quality questions with supportive information. We took on board the feedback from 2007 examination. Some questions from the 2008 examination were reported as ambiguous. The review board met and ambiguous questions were deleted from the examination and the scores recalculated.

Results: 648 trainees took UKITE 2008. Central organisation (86%) and local organisation (90%) were acceptable. 95% felt the examination pages were easy to use. There was difficulty in accessing the examination from NHS networks in some centers on the final day. 95% found there was educational benefit and 99% would like to sit again in 2009.

In the feedback from UKITE 2008, 85% of trainees felt it was better quality than 2007. The trainees approaching the FRCS examination are interested in using the database towards preparation.

In 2009 we aim to open the examination for SAS doctors, other surgical specialties and international trainees through elogbook.org.

Conclusion: UKITE has made progress in 2008. We aim to improve it further and open it to SAS doctors, other specialties and international trainees in 2009.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 528 - 529
1 Oct 2010
Ramappa M Bajwa A Kulkarni A McMurtry I Port A
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Introduction: Uncemented sockets have been used for revision with good results in the literature. Tantalum coated acetabular uncemented implant is the next generation implant. We used Tritanium (Stryker Corp. Kalamazoo, USA) for revision of acetabulum and present the early results.

Aim: To determine early results of porous tantalum coated modular acetabular cups in revision hip arthroplasty.

Patients and methods:41 acetabular revisions in 41 patients were performed using Tritanium acetabular uncemented sockets between March 2007 and March 2008. Posterior approach was used for all procedures. AAOS system for acetabular bone deficiency and Harris hip score for function was used for assessment.

Results: Mean age of the patients was 67 yrs (range 45–88). 95% of cups were fixed with screws for initial stability. AAOS classification showed there were 17 % Type 1, 49 % Type 2, 24% Type 3 and 5% Type 4 defects and 5 % had no defect. Bone graft was used to in 70% of patients, mostly autograft from the reamings. Mean Harris Hip Score improved from 68 pre-operatively to 84 at the last follow-up. Cup integration was seen in 93% patients. In two patients with pelvic discontinuity there was migration and in one loosening of the implant. One patient was treated for deep vein thrombosis and one patient for infection.

Conclusion: Early results of tantalum coated acetabular socket are encouraging, in providing adequate initial stabilisation for biologic fixation in segmental, cavitatory and combined defects. Facility to use locking screws in multiple directions may help in addressing pelvic discontinuity.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 549 - 549
1 Oct 2010
Hoang-Kim A Beaton D Bhandari M Kulkarni A Santone D Schemitsch E
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Background: Hip fracture trials have employed a wide range of patient-reported outcomes (PRO) suggesting a lack of consensus among clinicians on what are considered the most relevant outcomes. Variability in functional outcome reporting in hip fracture management creates challenges in the comparison of results across trials. The purpose of this study was to conduct a systematic review of the functional outcomes fielded in randomized controlled trials in post-operative hip fracture treatment for the aged. We hypothesized that over time there had been an increase in patient-reported outcomes along with aggregate scoring systems of hip function.

Methods: An electronic database search was conducted using key terms combining: ‘hip fracture’ with ‘RCT’ with ‘age 65 years and over’. s and titles were screened in duplicate and independently. All of the articles that met eligibility criteria were reviewed using the 21-point Detsky Quality Assessment Scale.

Results: In 2451 citations, 86 studies were included and also met accepted standards of inter-observer reliability (kappa, 0.92; 95% confidence interval, 0.87 to 0.98). The mean score (and standard error) for the quality of the randomized trials was: 75.8% ± 1.76% (95% confidence interval, 72.3%–79.3%) and 27 (32.6%) of the trials scored < 75%. Medical trials had a higher mean quality score than did surgical trials (83.7% compared with 72.7 %, p = 0.025). 59 trials (30 Surgical, 11 medical and 18 rehabilitation trials) scored > 75% in quality. Out of 86 trials, 8 (13.6%) used EQ-5D for utility and 6 (10.1%) used the SF-36 health status measures. At most, 12 trials used the same composite score: 12 (13.9%) ADL Katz Index, 9 (10.4%) trials used the HHS and 8 (9.3%) trials used Parker’s mobility score.

Conclusion: Although in the past decade more studies have made use of outcome instruments that capture both impairment and functional status in one aggregate score, there is a lack of standardized assessment.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 12 | Pages 1623 - 1626
1 Dec 2008
Kulkarni A Partington P Kelly D Muller S

Digital radiography is becoming widespread. Accurate pre-operative templating of digital images of the hip traditionally involves positioning a calibration object at its centre. This can be difficult and cause embarrassment. We have devised a method whereby a planar disc placed on the radiographic cassette accounts for the expected magnification. Initial examination of 50 pelvic CT scans showed a mean hip centre distance of 117 mm (79 to 142) above the gluteal skin. Further calculations predicted that a disc of 37.17 mm diameter, placed on the cassette, would appear identical to a 30 mm sphere placed at the level of the centre of the hip as requested by our templating software. We assessed accuracy and reproducibility by ‘reverse calibration’ of 20 radiographs taken three months after hip replacement using simultaneous sphere and disc methods, and a further 20 with a precision disc of accurate size. Even when variations in patient size were ignored, the disc proved more accurate and reliable than the sphere.

The technique is reliable, robust, cost effective and acceptable to patients and radiographers. It can easily be used in any radiography department after a few simple calculations and manufacture of appropriately-sized discs.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 29 - 30
1 Mar 2008
Kulkarni A Abudu A Tillman R Carter S Grimer R
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130 consecutive patients with metastastic tumours of the extremity bones treated with resection with or without major endoprosthetic reconstruction were studied retrospectively to determine the indication for surgery, complications, clinical outcome and oncological results of treatment.

The mean age at diagnosis was 61 (22 – 84). The tumours originated from a variety of organs. Lower extremity was involved in 104 and upper extremity in 26. Metastatic disease was solitary in 55 patients and multiple in 75 at the time of surgery. The median follow-up possible from the time of operation to review was 48 months (0-103).

The indication for surgery was radical treatment of solitary metastases with curative intent in 33, pathological fracture in 46, impending fracture in 27, failure of prior fixation devices in 17, painful swelling or extremity in 37. Surgical treatment included excision of expendable bones without reconstruction in 20 patients and resection with endoprosthetic reconstruction in 110 patients. 7 patients received adjuvant chemotherapy and the majority received adjuvant radiotherapy.

At the time of review, 58 patients had died at a mean time of 23 months (0–90) from surgery (53 from progressive metastatic disease and 5 from other causes). 72 were alive at mean follow-up of 22 months (1–103) from surgery. 36 patients (28%) were alive at 2 years post-surgery and 8 (6%) at 5 years. One patient died intra-operatively. Post-operative complications occurred in 32 patients (25%). 18 patients required further surgical procedures for dislocation, infection haematoma, stiff joint, plastic surgical procedures. All the patients had control of pain and 90% achieved desired mobility.

There was no difference in the survival of patients who presented with solitary and multiple metastases, renal and non-renal metastases, and upper or lower limb metastases.

Conclusion: Selected patients with bone metastases can benefit from resection and major bone reconstruction with acceptable morbidity. We have not identified predictable prognostic factors in these selected patients.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 30 - 30
1 Mar 2008
Kulkarni A Fiorenza F Grimer R Carter S Tillman R
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Only 1% of all primary bone tumours are situated in the distal humerus. Destruction of the distal humerus by tumour is rare and reconstruction of the distal humerus is challenging. Because of the amount of bone loss following tumour excision, excision arthroplasty or arthrodesis is impossible and hence some form of reconstruction is usually required. Allograft reconstruction and hemiarthroplasty are uncommon and lead to an unpredictable outcome.

Ten patients underwent endoprosthetic replacement of the distal humerus for bone tumours over a thirty one-year period. There were 8 primary and 2 secondary tumours and male to female ratio was 2:3. Average age of the patients was 47.5 years (15–76 years). Mean follow up was 8 years (9 months - 31 years). Four patients required further surgery, three having revision for asceptic loosening and two of these and one other later needing a rebushing. There were no permanent nerve palsies, infections, local recurrences or mechanical failures of the implant. Four patients died of their disease between 12 and 71 months after operation, all with their prosthesis working normally.

Average flexion deformity was 15 degrees (0–35) and average flexion of these patients was 115 degrees (110–135). The average TES Score for these patients was 73% (29% to 93%). The activities which the patients found to be no problem (TES score more than 4.5 out of 5) were: brushing hair, drinking from a glass, putting on make up or shaving, picking up small items, turning a key in a lock, doing light household chores and socialising with friends, whilst activities that proved difficult (TES score less than 3 out of 5) were: gardening and lifting a box to an overhead shelf. Pain was not a problem and only 1 of the surviving patients reported ever having to use regular analgesics.

Conclusions: Endoprosthetic replacement of the distal humerus and elbow joint is a satisfactory method of dealing with these unusual tumours in the long term.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 19 - 19
1 Mar 2008
Kulkarni A Ahrens H Abudu A Carter S Tillman R Grimer R
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Non-union of long bone fractures can be a challenging problem. There are several methods of treatment and they depend upon various patient factors, biology of non-union, and presence of infection. When faced with failure of treatment with biological reconstructive procedures patients have little choice. At our institute we have treated 10 such patients with radical excision and reconstruction using tumour endoprostheses as a last attempt to save the limb.

Median age of the patients was 71 years (25–85). 2 patients were male and 8 were female. Median follow-up was 49 months (8–229). 5 had infected non-union. Resection and massive endoprosthetic reconstruction involved the distal femur in 4 patients, proximal femur 3, distal humerus 2 and total Humerus in 1 patient. Time from diagnosis of non-union to treatment was 0 to 96 months (median 11 months) and patients had had 0 to 6 (median 3) previous operations 5 infected non-unions were operated as 2 stage procedures and received long term antibiotics. 4 out of 5 infected non-unions were salvaged. There were 5 complications, namely periprosthetic fracture, infection, a dislocated shoulder, radial nerve palsy, suture of bosing.

All the patients achieved immediate mobility and stability. Extendible prosthesis allowed partial correction of limb shortening.

Conclusion: Resection of established non-union and reconstruction with endoprostheses is a good salvage operation for elderly and low demand patients in whom time consuming biological reconstruction is not desirable.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 404 - 405
1 Sep 2005
Kulkarni A Hee-Kit W Chan Y
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Introduction Thoracic pedicle screws are increasingly being used for internal fixation. Surgeons and radiologists are often required to make decisions about the position of the screws in relation to the pedicle based on AP and lateral plain radiographs alone. We ventured to assess the value of orthogonal radiographs in determining the position of thoracic pedicle screws in 23 cadaveric thoracic vertebrae

Methods Disarticulated cadaveric thoracic vertebrae were used in this study. Pedicle screws were inserted in three positions: 1) within the pedicle, deliberately violating the 2) lateral cortex of the pedicle and 3) medial cortex of the pedicle. AP (antero-posterior) & lateral radiographs were obtained and presented to 6 readers (4 surgeons & 2 radiologists) in booklets consisting of AP views alone, lateral views alone and both AP & lateral views together in a sequential manner. The readers were asked to indicate the position of the screws and the results of the evaluation were compared to the actual position (axial views).

Results On AP views alone, the accuracy in detecting screws placed out of the pedicle laterally and medially were 93% and 76% respectively, while the accuracy for screws placed inside the pedicle was 85% . On LATERAL views alone, the accuracy for the same screw positions were 69%, 58% and 64% respectively. When AP + LATERAL views were considered together, the accuracy for the same screw positions were 93%, 80% and 87% respectively. Comparing the three groups, it was observed that screw positions were read more accurately in AP + LATERAL views (87%) compared to AP views alone (85%), or LATERAL views alone (64%). The sensitivity of correctly identifying screws placement is highest in AP + LATERAL (90%) views with a specificity of 94%. The specificity of detecting screws placed inside the pedicle is highest in AP (94%). The positive predictive value (PPV) of radiographs in general (AP +LATERAL) in detecting screws placed inside the pedicle, out of the pedicle laterally and medially were 73%, 92% and 86% respectively. The negative predictive value (NPV) of radiographs in general for the same screw locations were 90%, 96% and 76% respectively. On AP and AP + LATERAL views respectively, 25% and 23% of screws placed inside the pedicle were read as medially ‘out’. 10% of screws placed medially ‘out’ were read as ‘in’ on both AP and AP + LATERAL views. Inter-observer difference was substantial. In general, surgeons appeared to have consistently higher accuracy, sensitivity, specificity, PPV and NPV values compared to radiologists and fellows in determining screw position.

Discussion The positions of the screws appear to be most accurately detected when both AP and lateral x-rays are provided compared to AP or lateral alone. Screws that perforated the lateral cortex were the easiest and those that were medially out were the most difficult to identify. Screws passed inside the pedicle may create an unnecessary apprehension that they may be medial and screws passed medially may give a false sense of security that the screw is inside the pedicle. Radiographs are just one component in ensuring accurate pedicle screw placement and surgeon’s experience, in the use of tactile skills and anatomical knowledge continue to be vitally important in the safe placement of thoracic pedicle screws.