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The Bone & Joint Journal
Vol. 98-B, Issue 9 | Pages 1189 - 1196
1 Sep 2016
McDonald DA Deakin AH Ellis BM Robb Y Howe TE Kinninmonth AWG Scott NB

Aims

This non-blinded randomised controlled trial compared the effect of patient-controlled epidural analgesia (PCEA) versus local infiltration analgesia (LIA) within an established enhanced recovery programme on the attainment of discharge criteria and recovery one year after total knee arthroplasty (TKA). The hypothesis was that LIA would increase the proportion of patients discharged from rehabilitation by the fourth post-operative day but would not affect outcomes at one year.

Patients and Methods

A total of 242 patients were randomised; 20 were excluded due to failure of spinal anaesthesia leaving 109 patients in the PCEA group and 113 in the LIA group. Patients were reviewed at six weeks and one year post-operatively.


Bone & Joint Research
Vol. 3, Issue 6 | Pages 212 - 216
1 Jun 2014
McConaghie FA Payne AP Kinninmonth AWG

Objectives

Acetabular retractors have been implicated in damage to the femoral and obturator nerves during total hip replacement. The aim of this study was to determine the anatomical relationship between retractor placement and these nerves.

Methods

A posterior approach to the hip was carried out in six fresh cadaveric half pelves. Large Hohmann acetabular retractors were placed anteriorly, over the acetabular lip, and inferiorly, and their relationship to the femoral and obturator nerves was examined.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XV | Pages 2 - 2
1 Apr 2012
Reston SC McDonald DA Seigmeth R Deakin AH Scott NB Kinninmonth AWG
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The CALEDonian Technique™, promoting enhanced recovery after surgery, is a multimodal multidisciplinary technique. This has demonstrated excellent analgesic control allowing early mobilisation and discharge following TKA, whilst maintaining patient safety.

All patients follow a planned programme beginning with pre-operative out-patient education at the pre-assessment visit. An anaesthetic regimen consisting of pre-emptive analgesia is combined with a spinal/epidural with propofol sedation. Intra-articular local anaesthetic soft tissue wound infiltration by the surgeon under direct vision is supplemented by post-operative high volume intermittent boluses via an intra-articular catheter. Early active mobilisation is positively encouraged.

A prospective audit of over 1000 patients demonstrated 35% of patients mobilised on day 0 and 95% by day 1, with rescue analgesia required in only 5% of cases. 79% of patients experienced no nausea or vomiting helping reduce length of stay from six to four postoperative days. A catheterisation rate of 7%, a DVT rate of 0.6% and a PE rate of 0.5% remained within or below previously published levels.

Laboratory studies examining the performance of the epidural filter and injection technique used for the post-operative intra-articular injections demonstrated this to be robust and effective at preventing bacterial ingress. This in-vitro data is supported by clinical results demonstrating no increase in the deep infection rate of 0.7% since the implementation of the technique at our institution.

We conclude that the CALEDonian Technique™ effectively and safely improves patient post-operative recovery following TKA.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 12 - 12
1 Mar 2012
Kinninmonth AWG McDonald D Siegmeth R Monaghan H Deakin AH Scott N
Full Access

Purpose

We report our initial results of a new comprehensive patient care plan to manage peri-operative pain, enable early mobilisation and reduce length of hospital stay in TKA.

Methods and Results

A prospective audit of 1081 patients undergoing primary TKA during 2008 and 2009 was completed. All patients followed a planned programme including pre-operative patient education, pre-emptive analgesia, spinal/epidural anaesthesia with propofol sedation, intra-articular soft tissue wound infiltration, post-operative high volume intermittent ropivacaine boluses with an intra-articular catheter and early mobilisation. The primary outcome measure was the day of discharge from hospital. Secondary outcomes were verbal analogue pain scores on movement, time to first mobilisation, nausea and vomiting scores, urinary catheterisation for retention, need for rescue analgesia, maximum flexion at discharge and six weeks post-operatively, and Oxford score improvement.

The median day of discharge was post-operative day four. Median pain score on mobilisation was three for first post-operative night, day one and two. 35% of patients ambulated on the day of surgery and 95% of patients within 24 hours. 79% patients experienced no nausea or vomiting. Catheterisation rate was 6.9%. Rescue analgesia was required in 5% of cases. Median maximum flexion was 85° on discharge and 93° at six weeks post-operatively. Only 6.6% of patients had a reduction in maximum flexion (loss of more than 5°) at six weeks. Median Oxford score had improved from 42 pre-operatively to 27 at six weeks post-operatively. The infection rate was 0.7% and the DVT and PE rates were 0.6% and 0.5% respectively.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 560 - 560
1 Aug 2008
Clarke JV Dillon JM Deakin AH Kinninmonth AWG Picard F
Full Access

Total knee replacement (TKR) has become the standard procedure in management of degenerative joint disease with its success depending mainly on two factors: three dimensional alignment and soft tissue balancing. The aim of this work was to develop and validate an algorithm to indicate appropriate medial soft tissue release during TKR for varus knees using initial kinematics quantified via navigation techniques.

Kinematic data was collected intra-operatively for 46 patients with primary end-stage osteoarthritis undergoing TKR surgery using a CT-free navigation system. All patients had preoperative varus knees and medial release was made using the surgeon’s experience. From this data an algorithm was developed to define the medial release based on the pre-operative mechanical femoral-tibial angle with valgus stress;

No release (tibial cut only) when valgus stress > −2/3°. Moderate release (medial aspect of tibia +/− semimembranosous tendon) when valgus stress > −5° and < −2°. Extensive release (proximal) when valgus stress < −5°. If there was a fixed flexion deformity > 5° then a posterior release was performed.

This algorithm was validated on a further set of 35 patients where it was used to determine the medial release based only on the kinematic data. The post-operative varus and valgus stress angles for the two groups were compared and showed good outcomes in terms of distribution and outliers.

The results showed that the algorithm was a suitable tool to indicate the type of release required based on intra-operatively measured pre-implant valgus stress and extension deficit angles. It reduced the percentage of releases made and the results were more appropriate than the decisions made by an experienced surgeon.