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Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 87 - 87
1 Jul 2020
Akhtar RR Khan J Ahmed R
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To determine the number of patients with low back pain who have low serum Vitamin-D levels in our local population and the clinical efficacy of Vitamin-D supplementation on VAS and MODQ scores

This Prospective cohort study was conducted from 20th March 2016 to 19th March 2017. 600 patients were included in the study who met the inclusion criteria, i.e. patients presenting to the Out Patient Department (OPD) with low back pain for a duration of less than six months aged between 15 to 55 years. Venous blood withdrawn and serum levels of Vitamin-D measured. According to serum Vitamin-D levels, categorized as deficient, sufficient or excess. Those having deficient Vitamin-D levels (< 2 0 ng/dL) were given Vitamin-D supplementation as Oral 50,000 IU Vitamin-D3 daily for 05 days, then once weekly for 08 weeks while those having insufficient levels (20–30 ng/dL) given Oral 50,000 IU Vitamin-D3 once weekly for 08 weeks. Vitamin-D levels, Visual Analog Pain Scale (VAS) and Modified Oswestry Disability Questionnaire (MODQ) scoring done at baseline, 02, 03 and 06 months. Data analyzed using SPSS version 23.

Mean age of patients included in the study 44.21 ± 11.92 years. Out of the total, 337 (56.17%) were males and 263 (43.83%) females. Out of the total, 20.67%, 26.17% and 28.83% had mild, moderate and severe Vitamin-D deficiency, respectively. Predominantly patients with severe Vitamin-D deficiency presented in winters (October – February) (17.16%) as compared to other seasons. The most pre-dominant risk factor in patients with low Vitamin-D levels was smoking (21.33%). Mean baseline Vitamin-D levels were 13.32 ± 6.10 ng/dL and after supplementation these levels improved to 37.18 ± 11.72 ng/dL. VAS score improved from a mean baseline value to 81 to 36 at 6 months (p < 0 .01). Likewise, MODQ score decreased from a baseline mean of 46 to 25 at 6 months (p < 0 .01)

Vitamin D plays a crucial role in the musculoskeletal framework of the body. The deficiency is more prevalent in the youth due to sedentary lifestyle and indoor preference. Improvement in pain & functional disability with Vitamin-D supplementation

For any reader queries, please contact virgo_r24@hotmail.com


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 92 - 92
1 Jul 2020
Khan J Akhtar RR Ahmed R
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To compare the efficacy of intra-articular and intravenous modes of administration of tranexamic acid in primary Total Knee Arthroplasty in terms of blood loss and fall in haemoglobin level.

This randomized controlled trial was conducted from 12th May 2017 to 11th May 2017. Seventy eight patients were included in the study. Patients were randomly divided into group A and B. Group A patients undergoing unilateral primary total knee replacement (TKR) were given intravenous tranexamic acid (TXA) while group B were infiltrated with intra-articular TXA. Volume of drain output, fall in haemoglobin (Hb) level and need for blood transfusion were measured immediately after surgery and at 12 and 24 hours post operatively in both groups.

The study included 35 (44.87%) male and 43 (55.13%) female patients. Mean age of patients was 61±6.59 years. The mean drain output calculated immediately after surgery in group A was 45.38±20.75 mL compared with 47.95±23.86 mL in group B (p=0.73). 24 hours post operatively, mean drain output was 263.21±38.50 mL in intravenous group versus 243.59±70.73 mL in intra-articular group (p=0.46). Regarding fall in Hb level, both groups showed no significant difference (p>0.05). 12.82% (n=5) patients in group A compared to 10.26% (n=4) patients required blood transfusion post operatively (p=0.72).

Intra-articular and intravenous TXA are equally effective in patients undergoing primary total knee arthroplasty in reducing post operative blood loss.

For any reader queries, please contact drjunaidrmc@gmail.com


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 90 - 90
1 Jul 2020
Khan J Ahmed R
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To determine the effect of Dexamethasone on post-operative pain management in patients undergoing Total Knee Arthroplasty in terms of numerical pain rating scale and total opoid consumption.

This Randomized Controlled Trail (RCT) was conducted for 02 years (7th September 2015 to 6th September 2017). All patients undergoing primary Unilateral Total Knee Replacement (TKR) for Osteoarthritis knee were included in the study. Patients with poor glycemic control (HbA1c > 7.6), Hepatic/Renal failure, corticosteroids/ Immunosuppression drug usage in the last 06 months, known psychiatric illnesses were excluded from the study. All patients were operated by consultant Orthopaedic surgeon under Spinal Anaesthesia and tourniquet control using medial para-patellar approach. Patients were randomly divided into 02 groups, A and B. 79 patients were placed in each group. Group A given 0.1mg/kg body weight Dexamethasone Intravenously 15 minutes prior to surgery and another dose 24 hours post-operatively while in group B (control group) no Dexamethasone given. Post-operative pain using the numerical pain rating scale (NRS) and total narcotics consumed converted to morphine dose equivalent noted immediately post-op, 12-, 24- and 48-hours post-operatively. Data analysis done using SPSS version 23.

A total of 158 patients were included in the study. Of the total, 98 (62.02%) were females and 60 (37.98%) males. Average BMI of patients 26.94 ±3.14 kg/m2. Patients in group A required less post-operative analgesics (p < 0 .01) and had a better numerical pain rating scale score (p < 0 .01) as compared to group B. Pain scores at 24- and 48-hours post-op were significantly less for Dexamethasone group (p < 0 .01).

Use of Dexamethasone per- and post-operatively reduces the pain and amount of analgesics used in patients undergoing TKA.

For any reader queries, please contact drjunaidrmc@gmail.com


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 88 - 88
1 Jul 2020
Akhtar RR Khan J
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To compare the efficacy of local steroid injection with surgical decompression in treatment of carpal tunnel syndrome (CTS) in terms of frequency of pain.

This randomized controlled study was conducted at the Department of Orthopaedics for a duration of 01 year, i.e. from 20th April 2016 to 19th April 2017. 130 patients with carpal tunnel syndrome with moderate (Grade 2) and severe (Grade 3) pain were included. Lottery method was used to allocate the patients randomly into two groups. Group A contained 65 patients who were subjected to surgical decompression and 65 patients were in Group B who were injected with local steroid injection. Complete history was obtained from all patients. All the surgical decompressions through mini incision technique and injections procedures were performed. Information were recorded in a pre designed Performa.

Efficacy was observed significantly high in group B as compared to group A (87.7% vs. 72.3%, p=0.028).

Carpal Tunnel syndrome symptoms were alleviated with surgical decompression as well as local steroid injection at a follow up done after 1 month. However the steroid injections seem to have greater efficacy than surgical decompression, hence we suggest it for routine treatment of all patients with CTS.

For any reader queries, please contact virgo_r24@hotmail.com


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_10 | Pages 12 - 12
1 May 2016
Lombardo D Prey B Khan J Sabesan V
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Background

A challenge to obtaining proper glenoid placement in total shoulder arthroplasty is eccentric posterior bone loss and associated glenoid retroversion. This bone loss can lead to poor stability and perforation of the glenoid during arthroplasty. The purpose of this study was to evaluate the three dimensional morphology of the glenoid with associated bone loss for a spectrum of osteoarthritis patients using 3-D computed tomography imaging and simulation software.

Methods

This study included 29 patients with advanced glenohumeral osteoarthritis treated with shoulder arthroplasty. Three-dimensional (3D) reconstruction of preoperative CT images was performed using image analysis software. Glenoid bone loss was measured at ten, vertically equidistant axial planes along the glenoid surface at four distinct anterior-posterior points on each plane for a total of 40 measurements per glenoid. The glenoid images were also fitted with a modeled pegged glenoid implant to predict glenoid perforation.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 94 - 94
1 May 2016
Sabesan V Lombardo D Khan J Wiater J
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Purpose

With growing attention being paid to quality and cost effectiveness in healthcare, outcome evaluations are becoming increasingly important. This determination can be especially difficult in reverse shoulder arthroplasty (RSA) given the complex pathology and extensive disabilities in this patient population. Several different scoring systems have been developed and validated for use in various shoulder pathologies. The purpose of this study was to assess the use three outcome scores in a population of patients undergoing RSA. We aim to demonstrate the validity of three outcome scores in patients undergoing RSA, and to determine if one score or a combination of scores is superior to others.

Methods

Using a database of patients treated with RSA, we assessed preoperative and postoperative Constant Scores, American Shoulder and Elbow Surgeons (ASES) scores, and subjective shoulder values (SSV) in 148 shoulders. The outcomes at each scoring period were described and the scores were compared to one another as well as to active range of motion using linear regression modeling.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 28 - 28
1 Jan 2011
Swamy G Gangopadhyay S Khan J Calthorpe D
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Pyogenic haematogenous spinal infection in the elderly, described as spondylodiscitis, vertebral osteomyelitis and epidural abscess is considered a rare but life threatening condition. Our objective was to test the hypothesis that low index of suspicion leads to delayed diagnosis and referral for definitive treatment resulting in increased and perhaps avoidable medical morbidity, social drift including early mortality and to analyse pathological entities, complications and optimum treatment options.

We performed a retrospective review of medical records over 10-year period. Post-operative infections and patients under 65 years old excluded. Initial presentation, investigations and differential diagnosis, time to diagnosis, date and day of referral, mode of definitive treatment, pathologic entities, complications and outcomes were noted. Patient outcomes were measured as duration of treatment, length of hospital stay, complications, ambulatory status, complications, discharge destination and death. Outcomes were correlated with delayed diagnosis and referral.

46 elderly (age> 65) patients with a mean age of 71 years (range=65–91). 62% referral from physicians. Fever with malaise associated with chronic LBP was the commonest presenting complaint. There were 31 patients with discitis, 12 epidural abscess and 3 osteomyelitis. Lumbar spine was affected in 63% patients. Time to diagnosis ranged from 2–17 days with mean of 8 days. Mean referral time was 9 days with 39% referrals on Friday. Staphylococcus aureus (47%) was the commonest organism isolated. Duration of hospitalisation ranged from two to twelve weeks. 46% required surgical decompression with four cases of related mortality during acute hospital stay.

Time duration to spinal referral had direct correlation with increase in morbidity, social drift and mortality. The incidence of haematogenous spinal infection in the elderly has increased over the years in our series, contrary to popular belief. A high index of suspicion in elderly patients with PUO promotes early diagnosis and optimises outcome.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 483 - 483
1 Sep 2009
Swamy G Gangopadhyay S Khan J Calthorpe D
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Background: Pyogenic haematogenous spinal infection in the elderly, described as spondylodiscitis, vertebral osteomyelitis and epidural abscess is still considered a rare but life threatening condition.

Objective: To test our hypothesis that low index of suspicion leads to delayed diagnosis.

Late referral for definitive treatment may result in increased and perhaps avoidable medical morbidity, social and psychological drift, including early mortality.

Method: Retrospective review of medical records over 10-year period.

Patient pool obtained from theatre records, radiology and coding departments.

Post-spinal operative infections and patients under 65 years old excluded.

Initial presentation, admitting speciality, initial investigations and differential diagnosis, time to diagnosis, date and day of referral, mode of definitive treatment, pathologic entities, complications and outcomes were noted.

Patient outcomes were measured as duration of treatment, length of hospital stay, complications, ambulatory status, complications, discharge destination and death.

Outcomes were correlated with delayed diagnosis and referral.

Results: Single largest series [n=46] of elderly [age> 65] patients with pyogenic spinal infections to our knowledge.

Age ranged from 65–91 with mean of 71.

62% referral from Physician colleagues.

Fever with malaise associated with chronic LBP was the commonest presenting complaint.

34 patients had discitis and 12 had epidural abscess.

Time to diagnosis ranged from 2–17 days with mean of 8 days. Mean referral time to spinal team was 9 days with 39% referrals on Friday.

Duration of hospital ranged from two weeks to three months.

46% required surgical decompression with four cases of related mortality during acute hospital stay.

Conclusions: Time duration to Spinal referral had direct correlation with increase in morbidity, social and psychological drift, and mortality.

The incidence of haematogenous spinal infection in the elderly has increased over the years in our series, contrary to popular belief.

A high index of suspicion in elderly patients with PUO promotes early diagnosis and optimises outcome.