Objectives The objective of this study was to investigate accelerated bone healing in patients with femoral shaft fractures.

Methods Data on patients with diaphyseal femoral fractures admitted to our trauma unit between 1997 and 2002 was collected and analysed. Patients were categorised into three groups by the presence or absence of head injury, and the reamed or undreamed nailing technique used. Severity of head injury was quantified using abbreviated injury score (AIS) and Glasgow Coma Scale (GCS). Time to bony union was assessed from serial of x-rays and clinical examination.

Patients were followed to discharge in outpatient clinics until bony union.

Results Group 1 ( Patients with head injury)

In total 17 patients (14 male, 3 female)

mean age 29.4(14–53)

open fractures 2

Mean AIS 3.2 (2–5)

Fracture treatment was reamed femoral nail

Bony union 10.5(6–22)weeks

Group 2 ( Patients without head injury)

Intotal 25 patients(19 male, 6 female)

Mean age 32(16–81)

Open fractures 2

Fracture treatment was reamed femoral nail

Bony union 20.5(14–32)weeks

Group 3 ( Patients without head injury)

In total 24 patients(18 male, 6 female)

Mean age 47(17–83)

Open fractures 2

Fracture treatment was unreamed femoral nail

Bony union 26.9 (21–32) weeks

Conclusion This study supports rapid bone union in the presence of head injury. Further research is indicated to provide a definate answer, specially mesenchymal cell and their control pathways which could allow further development of their potential therapeutic uses.

Total Knee Replacement (TKR) is one of the commonest and successful orthopaedic operations performed in the UK with good long term results. The Natural knee (Sulzer – Centerpulse ) is one of the various types of prostheses available. This implant is unique because of the trochlear notch over the anterior surface of the femoral prosthesis that allows natural tracking of the patella and an asymmetric anatomical tibial component. To our knowledge there are no studies reviewing outcome of Natural Knee Replacement from the UK.

We reviewed 177 consecutive TKRs in 147 patients including 30 bilateral simultaneous or staged procedures using Natural Total Knee prosthesis performed during 1994 to 1998, with a minimum of five years follow up. All these surgeries were performed at a single NHS District General Hospital by different grades of surgeons including consultants and trainees.

12 patients died and 10 were lost to follow up. 155 knees were available for final follow up and evaluation. We carried out an outcome related to patient satisfaction using Oxford Knee questionnaire system. We compared the preoperative and post operative scoring using the questionnaire and found an improvement of the score after the procedure. The average improvement in scores before and after surgery was 30 (20 pre op to 50 post op). Out of 155 knees evaluated, 143 knees (92%) were happy with the results while the rest did not have satisfaction with surgery. Complications included anterior knee pain in 12, DVT in 40 , non fatal pulmonary embolism in 2, wound infection in 3, stiffness in 8 of which 5 needed manipulation under anaesthesia, there were 2 revisions of which one knee was done for infection and one for a loose femoral component.

Our results suggest that the five year follow-up results of this prosthesis are at par with other commonly used knee replacement prostheses in the UK.