There is a paucity of studies analyzing the rates of revision total knee arthroplasty in diabetic patients stratified by glycated hemoglobin levels. The purpose of this study was to: 1) determine the incidence of revision TKA; 2) correlate the percent of glycated hemoglobin with incidence of revision; and 3) determine the cause of revision in diabetic patients stratified by glycated hemoglobin level. We utilized a national private payer dataset within the PearlDiver database from 2007 to 2015 quarter 1 to determine who had diabetes and underwent TKA. There were 424,107 patients who were included in the analysis. We determined the incidence of revision TKA in the overall cohort, in addition to stratifying the incidence by glycated hemoglobin levels. To determine the effect of glycated hemoglobin levels on revision TKA rate, we performed a correlation analysis between the level of glycated hemoglobin and the incidence of revision TKA. We performed descriptive statistics of the underlying cause of revision TKA in both the overall and stratified cohortsIntroduction
Methods
It is well established that diabetic patients undergoing total knee arthroplasty (TKA) are more susceptible to infection, problematic wound healing, and have overall higher complication rates. However there is a paucity in current literature investigating the effects of hypoglycemia on TKA. The purpose of this study was to determine the effect of hypoglycemia on TKA revision (rTKA) incidence analyzing a national private payer database for procedures performed between 2007 and 2015 Q1. A retrospective review of a national private payer database within the PearlDiver Supercomputer application (Warsaw, IN, USA) for patients undergoing TKA with blood glucose levels ranging from 20 to 219 mg/ml, in increments of 10 mg/ml, was conducted. Patients who underwent TKA were identified by Current Procedural Terminology (CPT)-27447 and International Classification of Disease (ICD) code 81.54. Glucose ranges were identified by filtering for lab identifier values unique to the PearlDiver database. Revision TKA and causes for revision, including mechanical loosening, failure/break, periprosthetic fracture, osteolysis, infection, pain, arthrofibrosis, instability, and trauma) were identified with CPT and ICD-9 Codes. Statistical analysis of this study was primarily descriptive.Introduction
Methods