This prospective clinical study investigates the relationship between intra-compartmental pressure and soft tissue oxygenation (StO2) measured non-invasively by near-infrared spectroscopy (NIRS) in patients at risk of acute compartment syndrome.

Patients (over 13 years) with fractures of the tibial diaphysis or high-energy fractures of the forearm or distal radius, or patients with soft tissue injury were recruited. Non-invasive and invasive monitoring was carried out pre and post operatively. The ‘Delta P’ value (DP) was calculated as the compartment pressure subtracted from the diastolic blood pressure. The threshold for fasciotomy was a DP < 30mmHg. Non-invasive tissue saturation measurements and pressure measurements were taken from the same compartment (anterior tibial or volar forearm). StO2 values were simultaneously recorded from the contralateral (uninjured) limb at the same anatomical site. All patients had the difference between the StO2 value on the injured and uninjured sides calculated (‘StO2 difference’).

42 patients with tibial diaphyseal fractures, 2 patients with forearm fractures and one case with thigh swelling were recruited to the study. The mean age was 40 years (SD 17 years). 11 patients underwent a four-compartment lower leg fasciotomy determined by a DP < 30mmHg. Patients who required a fasciotomy had an ‘StO2 difference’ that was 20% lower (p = 0. 002) compared to those who did not develop acute compartment syndrome. This suggests that patients who require a fasciotomy have reduced StO2 values on their injured legs compared to the contralateral (uninjured) side.

We have observed that non-invasive StO2 measurements for patients over 13 years at risk of acute compartment syndrome, correlates with the requirement for a fasciotomy as defined by P < 30mmHg. We are optimistic that near-infrared spectroscopy (NIRS) will be a reliable new non-invasive technique for detection of an acute compartment syndrome.

A carbonated apatite cement with a high compressive strength was used in the treatment of tibial plateau fractures. There were 41 patients (20 male; 21 female; mean age 59 years). All patients had isolated tibial plateau fractures.

There were 15 B2.2, 23 B3.1 and 3 B2.3 fractures. Fractures were fixed with limited internal fixation using a short anterior parapatellar incision. Reduction and fixation were initially achieved. Once this was carried out the void under the elevated plateau was filled using calcium phosphate cement. A buttress plate was used in one case, screws or K-wires in 33 cases and calcium phosphate cement alone in 7 cases. Patients were mobilised partially weight bearing in a hinged knee brace and allowed full weight bearing at 6 weeks.

Reductions were anatomic (< 2mm displacement in 32 (78%) cases, satisfactory (3-5mm displacement) in 7 (17%) cases and imperfect (> 5mm) in 2 (5%) patients. Extrusion of some calcium phosphate cement into surrounding soft tissue occurred in one case. This material resorbed with no adverse effects. Loss of reduction was observed in 6 (15%) cases. There were no other significant complications. Thirty-seven patients (90%) had more than 120 degrees of knee flexion at 6 months.

Calcium phosphate cement is an alternative to the use of bone grafting in any area of cancellous subject to compressive load. It is ideal for use in tibial plateau fractures with compressed subchondral bone after elevation. It obviates the need for buttress plating and bone grafting and there is no bone graft donor site morbidity. Patients are able to mobilise more rapidly and early discharge is facilitated.

Calcium phosphate cement is a promising development in the management of tibial plateau fractures and initial results suggest it may be more effective in maintaining reduction that standard methods of fixation and grafting.

The detection and treatment of acute compartment syndrome following trauma is critical if contractures, delayed fracture healing and possible amputations are to be avoided. The current standard for monitoring relies on invasive compartment pressure measurements. These require an additional procedure and cause discomfort to the patient. This prospective clinical study investigates the relationship between the intra-compartmental pressure and soft tissue oxygenation (%StO₂) measured non-invasively by near-infrared spectroscopy (NIRS) in patients at risk of acute compartment syndrome.

Adults with acute tibial or radial diaphyseal fractures were recruited on admission to the orthopaedic trauma unit. Non-invasive and invasive monitoring over anterior tibial or volar forearm compartments was carried out from admission and continued post-operatively. The differential pressure (ΔDP) was calculated as the compartment pressure subtracted from the diastolic blood pressure. The threshold for fasciotomy was a ΔDP < 30mmHg. StO₂ values were simultaneously recorded from the contralateral (uninjured) limb at the same site. All patients had the difference between the StO₂ value on the injured and uninjured sides calculated (‘StO₂ difference’).

Sixty patients with tibial fractures and 5 patients with forearm fractures were recruited. The mean age was 39 years (S.D.18 years). Fourteen patients underwent a four-compartment lower leg fasciotomy determined by a ΔDP < 30mmHg.

We have observed that the difference in StO₂ between limbs (measured non-invasively) was significantly lower in patients undergoing a fasciotomy. This suggests that NIRS is able to detect a change in oxygenation of the soft tissues in trauma patients developing an acute compartment syndrome. We are optimistic that near-infrared spectroscopy (NIRS) will be a reliable new non-invasive technique for detection of an acute compartment syndrome.

We performed a prospective, randomised trial on 120 patients with redisplaced fractures of the distal radius comparing four methods of treatment. The four treatment groups, each containing 30 patients, were remanipulation and plaster, open reduction and bone grafting, and closed external fixation with and without mobilisation of the wrist at three weeks.

The radiological results showed improvement in angulation of the distal radius for the open reduction and bone grafting group. Functional results at six weeks, three and six months and at one year, however, showed no difference between any of the four groups. The main influence on final outcome was carpal malalignment which had a statistically significant negative effect on function.