Aims: to evaluate effects of trombocyte growth factors derived from platelets concentrate associate to intra-medullary nailing in stimulation of healing of diaphy-seal lower limbs pseudoarthroses.

Methods: 4 patients with atrophic tibial pseudoarthrosis and 2 patients with atrophic femoral pseudoartrhrosis were treated with high diameter reamed intramedullary nail. The site of pseudoarthrosis was stimulated using percutaneous injection of platelets concentrate under image intensifier control without opening. We evaluate healing of pseudoarthrosis with radiographic controls at 15 days, 1 month after surgery and after every month until consolidation. We gave partial weight bearing two days after surgery for 2 weeks and then total weight bearing.

Results: All patients with tibial fractures had radiological healing of pseudoarthrosis site within 3 months. All patient with femoral fracture healed in 4 months.

Conclusions: Although the number of treated patients is low and follow up is short, our results are remarkable either about consolidation or about early weight bearing.