Disc 1(control) contained Palacos R or CMW1 cement without any added antibiotic. Disc2 contained Palacos R or CMW1 with gentamicin. Disc 3 contained Palacos R or CMW1 with teicoplanin. Disc 4 contained Palacos R or CMW1 with gentamicin and teicoplanin powder. The discs containing teicoplanin were prepared by adding teicoplanin powder (2gm) to the respective cement powder (40 gm with or without 0.5gm of gentamicin) and then adding the monomer (vacuum mixing). All the discs were immersed in 50 ml normal saline bath in a sterile pot and maintained at temperature of 37 deg Celsius. 24 hours later a 5ml sample was taken from each pot for assay, to measure the amount of antibiotic eluted, using fluorescence polarization immuno-assay technique. The discs were then removed from the pots, washed with normal saline and reimmersed in a fresh 50 ml saline pot. This procedure was repeated at hours 48, 72, 120 and week 1, 2, 3 &
6 for all discs.
Gentamicin eluted from disc4 was higher than disc2 (94.9 v 34.37. p<
0.0003). Teicoplanin eluted from disc4 was higher than disc3 (202.1 v 147.57. p<
0.004).
Gentamicin eluted from disc4 was higher than disc2 (144.17 v 86.43. p<
0.0004). Teicoplanin eluted from disc4 was less than disc3 (140.17 v 213.73. p<
0.008)
Comparing only the cylindrical subgroup (three missing patients), the DEXA measurements at 2, 3 and 7 years of follow-up were: 0.88, 0.84 and 0.80 g/cm2 under the internal baseplate; 0.79, 0.78 and 0.77 under the external one, and 0.99, 0.96 and 0.99 under the stem.
The survival was calculated used Kaplan-Meier method, considering revision surgery as the analyzed event. Age and gender relation with survival were analyzed using the Log-Rank test.
A patient with a fractured coracoid process in association with a dislocation of the shoulder is reported. The fracture was not recognised initially, and early mobilisation was encouraged; the widely separated fracture did not heal and a painful pseudarthrosis developed. We believe that this association may not be as rare as generally supposed, and emphasise the importance of careful clinical examination in patients with shoulder dislocation. If a coracoid fracture is suspected, lateral or oblique radiographs should be taken to confirm the diagnosis. A further radiograph after reduction is a useful precaution.
Severe crush injuries affecting the bones of the carpus are rare. We review the nine cases that have previously been described and report four additional cases which we have treated and followed up. All 13 present remarkable similarities, with disruption of the carpal arch through the capitate-hamate articulation distally and the piso-triquetral joint proximally. Three slightly different variations of this pattern of fracture-dislocation are identified. The flexor retinaculum must be involved to allow the displacement which is seen, and there is usually an extensive laceration of the thenar eminence. Treatment by closed reduction is usually successful. Long-term follow-up shows that, in the absence of nerve or vascular damage, the results are surprisingly good.