Anterior stabilisation has been shown to be superior in the treatment of the lumbar and thoraco-lumbar scoliosis, both in regard to the correction of the curves and to the number of fused vertebrae. Since 1995, with the emergence of third-generation locking devices, we have extended the indication of anterior fixation to double major scoliosis with lumbar predominance, operating exclusively on the lumbar curve and allowing the thoracic curve to correct itself. We report this experience with respect to 12 patients. The patients consisted of 11 girls and one boy, mean age 16.6 years (range 12–29). The mean preoperative Cobb angle was: lumbar: 51° (41–72), dorsal 28° (range 21–45). All patients showed a lateral deviation of the trunk with asymmetry of the lumbar region. Of the 12 patients, 11 received stabilisation by EUROS instruments from D11 to L3 and one from D10 to L3. The mean follow-up is 44 months (range 15–77 months). A vertebral fusion was achieved for 94 % of the spaces (46/49). In the fixation zone, a 72% correction rate was achieved, whereas in the non-treated zone of the dorsal rachis, the rate of spontaneous correction was 32 %. In total the angle loss has been on average 4°. The study assessed the horizontal position of the disk underlying the zone of the arthrodesis; in other words the L3 – L4 disk showed the presence of an average gradient angle of 7° with a range from 0° to 17°. No post-operative complications were observed, but 7 of 12 patients have had immediate and transient sympathectomy after-effects, with a modification of the ipsilateral limb temperature at the level of the instrumental access site. Anterior stabilization of the thoracolumbar curve in double major scoliosis with lumbar predominance seems to be preferred to posterior correction. This technique, by preserving the posterior musculature, makes it possible to save from 1 to 2 disk downwards. In turn, this makes it possible to correct the lateral translation and the realignment of the trunk starting with fusion limited to the lumbar spine. It is imperative to avoid hypercorrection of the thoraco-lumbar curve and even leave a bit of curve in the in situ modelling of the rod. Then the lumbar curve can be balanced with the dorsal curve and avoid an increase in the lumbosacral counter-curve with the risk in of rotatory dislocation in adult age. Since we have started using this technique, we have not had to perform double correction, anterior and posterior, for double major scoliosis with lumbar predominance.