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Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_2 | Pages 3 - 3
1 Mar 2022
Guta D Santini A Fountain J Scott S Rourke H Davidson J Folb J
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Aims

The International Consensus Meeting on Musculoskeletal Infection (ICM, Philadelphia 2018) recommended histology as one of the diagnostic tests although this is not routinely used in a number of UK hospitals. This study aims to explore the role of histology in the diagnosis of infection and whether it is of practical use in those cases where the microbiology samples are either diagnostically unclear or do not correspond to the pre-operative diagnosis or the clinical picture.

Patients and Methods

We identified 85 patients who underwent revision knee arthroplasty for either septic or aseptic loosening and for whom both microbiology and histology samples were taken. The procedures were performed by the senior experienced surgeons specialised in revision knee arthroplasty in two centres from Liverpool. Each patient had a minimum of five tissue samples taken, using separate knife and forceps and each sample was divided in half and sent for microbiology and histology in different containers.

Fifty-four patients (63.5%) underwent a single-staged revision; ten patients (11.8%) underwent the 1st stage of a two staged revision; eleven patients (12.9%) underwent the 2nd stage of a two staged revision; one patient (1.2%) underwent an additional revision stage; three patients (3.5%) were treated with a DAIR; three patients (3.5%) had a 2-in-1 revision; two patients (2.4%) had a debridement and polyethylene exchange; and one patient (1.2%) had an arthroscopy biopsy of knee replacement.

The cost to process five microbiology samples for each patient was £122.45 on average and for the five histology samples was £130.


The Bone & Joint Journal
Vol. 103-B, Issue 1 | Pages 164 - 169
1 Jan 2021
O'Leary L Jayatilaka L Leader R Fountain J

Aims

Patients who sustain neck of femur fractures are at high risk of malnutrition. Our intention was to assess to what extent malnutrition was associated with worse patient outcomes.

Methods

A total of 1,199 patients with femoral neck fractures presented to a large UK teaching hospital over a three-year period. All patients had nutritional assessments performed using the Malnutrition Universal Screening Tool (MUST). Malnutrition risk was compared to mortality, length of hospital stay, and discharge destination using logistic regression. Adjustments were made for covariates to identify whether malnutrition risk independently affected these outcomes.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 57 - 57
1 Mar 2017
Ul Islam S Carter P Fountain J Afzaal S
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Implant choice was changed from cemented Thompson to Exeter Trauma Stem (ETS) for treatment of displaced intra-capsular neck of femur fractures in University Hospital Aintree, Liverpool, United Kingdom (a major trauma center), following the NICE guidelines that advised about the use of a proven femoral stem design rather than Austin Moore or Thompson stems for hemiarthroplasties.

The aim of our study was to compare the results of Thompson versus ETS hemiarthroplasty in Aintree.

We initially compared 100 Thompson hemiarthroplasties that were performed before the start of ETS use, with 100 ETS hemiarthroplasties.

There was no statistically significant difference between the two groups in terms of patients' demographics (age, sex and ASA grade), intra-operative difficulties/complications, post op medical complications, blood transfusion, in-patient stay and dislocations.

The operative time was statistically significantly longer in the ETS group (p= .0067). Worryingly, the 30 days mortality in ETS group was more than three times higher in ETS group (5 in Thompson group versus 16 in ETS group. P= .011).

To corroborate our above findings we studied 100 more consecutive patients that had ETS hemiarthroplasty. The results of this group showed 30 day mortality of 8 percent. However the operative time was again significantly longer (p= .003) and there was 18 percent conversion to bipolar hemiarthropalsty. Moreover there was statistically significant increased rate of deep infection (7%, p = .03) and blood transfusion (27%, p = .007).

This we feel may be due to longer and more surgically demanding operative technique including pressurised cementation in some patients with significant medical comorbidities.

Our results raise the question whether ETS hemiarthoplasty implant is a good implant choice for neck of femur fracture patients. Randomised control trials are needed to prove that ETS implant is any better than Thompson hemiarthroplasty implants in this group of patients.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 575 - 575
1 Sep 2012
Selvaratnam V Fountain J Donnachie N Thomas T Carroll F
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INTRODUCTION

Tranexamic Acid (TA) has been shown to decrease peri-operative bleeding in primary Total Knee Replacement (TKR) surgery. There are still concerns with regards to the increased risk of thromboembolic events with the use of TA. The aim of this study was to assess whether the use of pre-operative TA increased the incidence of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) in TKR.

METHODS

Patients who underwent primary TKR between August 2007 and August 2009 were identified from the databases of three surgeons within the lower limb arthroplasty unit. A retrospective case notes analysis was performed. DVT was diagnosed on Duplex Ultrasound Scan and PE on CT Pulmonary Angiogram. A positive result was a diagnosis of DVT or PE within 3 months of surgery.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 81 - 81
1 Jul 2012
Haughton D Fountain J Barton-Hanson N
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Purpose

Investigate the functional outcome of medial patellofemoral ligament (MPFL) surgery for patella instability.

Compare functional outcome of direct MPFL repair and reconstruction using hamstring graft.

Methods

All patients that underwent MPFL surgery for patella instability between 2007-2010 were retrospectively identified from operative records. Patients were divided based on whether they underwent direct repair of MPFL, or reconstruction using hamstring graft. The Kujala scoring questionnaire for patellofemoral disorders (max score 100) was used to assess their functional outcome following surgery.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 192 - 193
1 May 2011
Robinson S Fountain J Pennis B
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Aims: To assess whether patients undergoing one or two level open decompression of their lumbar spinal stenosis could have an interspinous device inserted with equal or less risk of complications and whether patient satisfaction is improved.

Background: The reported incidence of lumbar spinal stenosis [LSS] varies [1.7% to 8%], as do the results of open surgical decompression. Implanting interspinous devices [ID] to relieve symptoms of LSS is a newer concept which has good short term results.

Patients: Data was collected from 48 consecutive patients undergoing one or two level decompressions for symptoms of lumbar spinal stenosis from February 2008 to March 2009.

Methods: Retrospective case note analysis of clinic letters, operation notes and inpatient stays was carried out. Two types of interspinous device (BacJac and X-stop) were used and the results have been collated.

Results: 29 open decompressions [22 one level, 7 two level] were performed compared to 19 interspinous device insertions [7 one level, 9 two level]. Surgery was performed for patients with leg pain although 27 patients had concomitant back pain.

The average age of the patients for open decompression (63yrs +/− 11) compared to interspinous device (63yrs +/− 9) was equal. Male to female ratio for Open Vs ID [1.4:1 Vs 1.1:1] did not differ significantly (p = 0.39). The ASA grades were higher for the interspinous device group with an average of 2.5 compared to 2.1 in the open group.

The length of anaesthetic was on average shorter for the interspinous devices, which included a higher proportion of 2 level decompressions. The average length of stay on average was identical at 1.3 days, complications were similar [5% Vs 7%] with patient satisfaction higher [81% Vs 68%], although statistically insignificant [p=0.79]

Conclusion: There are certain criteria advised by the American Academy of Orthopaedic Surgeons to aid in selection of suitable patients for interspinous device insertion. 10 of the 29 patients for open decompression fitted these criteria.

Interspinous device insertion is a less invasive procedure and can be carried out on patients with a higher anaesthetic risk, even being performed under sedation. It should be considered for patients with symptoms of LSS instead of open decompression as there is no effect on length of stay or complication rate and there is a trend toward a decrease in anaesthetic time with improved patient satisfaction in the short term.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 580 - 580
1 Oct 2010
Mahmood A Fountain J Theodoridis A Vasireddy N Waseem M
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The aim of the study was to compare the radiological findings of wrist arthrogram with wrist arthroscopy. This allowed us to establish the accuracy (sensitivity, specificity) of MRI arthrogram as a diagnostic tool. Thirty patients (20 female and 10 male) have undergone both wrist MRI arthrogram and wrist arthroscopy over the last 3 years at Macclesfield District General Hospital. The mean age at arthrogram was 42.4 years with an average 6.7 month gap between the two procedures.

The MRI arthrogram was reported by a consultant radiologist with an interest in musculoskeletal imaging and the arthrosopies performed by two upper limb surgeons. Patients undergoing both procedures were identified. The arthrogram reports and operation notes were examined for correlation. Three main areas of pathology were consistently examined: TFCC (triangular fibrocartilage complex), scapholunate and lunatotriquetral ligament tears. The sensitivity and specificity of arthrogram was calculated for each. Other areas of pathology were also noted.

In the case of TFCC tears MRI arthrogram had a 92.3% sensitivity and 54.6% specificity. The lunatotriquetral ligament examination with this technique was 100% sensitivity and specificity. However for scapholunate ligament tears it only had 50% sensitivity and 77.8% specificity.

Wrist arthrogram and arthroscopy are both invasive techniques and equally time consuming. In cost terms the arthrogram remains cheaper but is superseded by arthroscopy as it is both diagnostic and therapeutic.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 407 - 408
1 Jul 2010
Fountain J Jakaraddi C Pope J Davidson J Santini A
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We present a prospective trial examining the effect of posterior tibial slope at total knee arthroplasty (TKA) on the range of movement and functional outcome.

Current literature shows little difference clinically in TKA with increasing posterior tibial slope. Previous studies have been retrospective or involved small numbers and may represent poor ligament balancing or inaccurate alignment.

In a prospective, double-blinded, randomised controlled trial, 250 patients undergoing primary Profix TKA, were randomised to receive either a 0 or 4 degree posterior tibial cut. Range of movement (ROM) was measured pre-operatively, at 3 months and 1 year by a single clinical physiotherapist. SF-12 and WOMAC scores were calculated at the same visit. Both patient and physiotherapist were blinded to the angle of tibial slope.

Mean one year post operative ROM was greater by 2 degrees (p=0.470) in those with a 4 degree tibial slope. Post operatively both groups had significant improvement in functional outcome scores. A 0.2 (p= 0.892) and 0.51 (p= 0.707) greater improvement in SF12 physical score and mental scores respectively was found in the 0 degree group at one year. There was also a 1.09 (p=0.718) greater improvement in WOMAC score with a 0 degree slope.

In conclusion increased posterior tibial slope gives a marginally better but non-significant post operative ROM and makes no significant difference to functional outcome.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 60 - 60
1 Mar 2009
Fountain J Anderson A Flowers M Bell M
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Introduction: This study examined the cohort of patients selectively screened over a 5 year period with ultrasonography according to our risk factors (positive Ortolani or Barlow manoeuvre, breech presentation, first degree affected relative and talipes equinovarus) for developmental hip dysplasia (DDH). The aims were to evaluate the success of those managed in a Pavlik harness and identify predictive factors for those that failed treatment.

Methods: 1181 patients were selectively screened between 1999 and 2004. Of those, 128 patients (189 hips) were identified as having hip instability. Failure was defined as inability to achieve or maintain hip reduction in a Pavlik harness. A proforma was designed to document patients’ risk factors and ultrasound findings at time of initial dynamic ultrasound scan where the senior radiographer and treating consultant were present. Each hip was classified according to Graf type. Acetabular indices were recorded prior to discharge.

Results: All 128 patients with hip instability were managed in a Pavlik harness. This was abandoned for surgical treatment in 9 patients (10 hips) giving a failure rate of 5.3 % (0.17 per 1000 live births). All those successfully managed had an acetabular index of less than 30 degrees at follow up (6 – 48 months). 7 hips in the series were classified as Graf type IV, of these, 6 went on to fail management in a Pavlik harness. 67% of those that failed were also breech presentation compared to 22% of those managed successfully. There were no complications associated with management in a Pavlik harness. 16 patients born within our region presented after 12 weeks of age with DDH resulting in a late presentation rate of 0.3 per 1000 live births.

Discussion: Our overall rate of selective screening is 14 per 1000 live births with a subsequent treatment rate of 2.3 per 1000 is comparable with other centres. Our rate of failure for DDH in a Pavlik harness 0.17 per 1000 live births is an improvement on any previously published results. Irreducible hips, Graf type IV hips and breech presentation correlated with a high likelihood of treatment failure.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 267 - 267
1 May 2006
Fountain J Anderson A Bell M
Full Access

Introduction: This study examined the cohort of patients selectively screened over a 5 year period with ultrasonography according to our risk factors (positive Ortolani or Barlow manoeuvre, breech presentation, first degree affected relative and talipes equinovarus) for developmental hip dysplasia (DDH). The aims were to evaluate the success of those managed in a Pavlik harness and identify predictive factors for those that failed treatment.

Methods: 728 patients were selectively screened between 1999 and 2004. Of those, 128 patients (189 hips) were identified as having hip instability. Failure was defined as inability to achieve or maintain hip reduction in a Pavlik harness. A proforma was designed to document patients’ risk factors and ultrasound findings at time of initial dynamic ultrasound scan where the senior radiographer and treating consultant were present. Each hip was classified according to Graf type. Acetabular indices were recorded prior to discharge.

Results: All 128 patients with hip instability were managed in a Pavlik harness. This was abandoned for surgical treatment in 9 patients (10 hips) giving a failure rate of 5.3 %. All those successfully managed had an acetabular index of less than 30 degrees at follow up (6 – 48 months). 7 hips in the series were classified as Graf type IV, of these, 6 went on to fail management in a Pavlik harness. 67% of those that failed were also breech presentation compared to 22% of those managed successfully. There were no complications associated with management in a Pavlik harness.

Discussion: Our overall rate of selective screening is 14 per 1,000 with a subsequent treatment rate of 2.3 per 1,000, which is comparable with other centres. Our rate of failure for DDH in a Pavlik harness (5.3 %) is extremely encouraging. Graf type IV hips and breech presentation correlated with a high likelihood of treatment failure.