Anterior-posterior (AP) x-rays are routinely taken following total hip replacement to assess placement and orientation of implanted components. Pelvic orientation at the time of an AP x-ray can influence projected implant orientation.1However, the extent of pelvic orientation varies between patients.2Without compensation for patient specific pelvic orientation, misleading measurements for implant orientation may be obtained. These measurements are used as indicators for post-operative dislocation stability and range of motion. Errors in which could result in differences between expectations and the true outcome achieved. The aim of this research was to develop a tool that could be utilised to determine pelvic orientation from an AP x-ray. An algorithm based on comparing projections of a statistical shape model of the pelvis (n=20) with the target X-ray was developed in MATLAB. For each iteration, the average shape was adjusted, rotated (to account for patient-specific pelvic orientation), projected onto a 2D plane, and the simulated outline determined. With respect to rotation, the pelvis was allowed to rotate about its transverse axis (pelvic flexion/extension) and anterior-posterior axis (pelvic adduction/abduction). Minimum root mean square error between the outline of the pelvis from the X-ray and the projected shape model outline was used to select final values for flexion and adduction. To test the algorithm, virtual X-rays (n=6) of different pelvis in known orientations were created using the algorithm described by Freud et al.3The true pelvic orientation for each case was randomly generated. Angular error was defined as the difference between the true pelvic orientation and that selected by the algorithm. Initial testing has exhibited similar accuracy in determining true pelvic flexion ( Although the algorithm is still under development, the low mean, maximum, and standard deviations of error from initial testing indicate the approach is promising. Ongoing work will involve the use of additional landmarks for registration and training shapes to improve the shape model. This tool will allow surgeons to more accurately determine true acetabular orientation relative to the pelvis without the use of additional x-ray views or CT scans. In turn, this will help improve diagnoses of post-operative range of motion and dislocation stability.