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The Bone & Joint Journal
Vol. 103-B, Issue 7 | Pages 1238 - 1246
1 Jul 2021
Hemmerling KJ Weitzler L Bauer TW Padgett DE Wright TM

Aims

Dual mobility implants in total hip arthroplasty are designed to increase the functional head size, thus decreasing the potential for dislocation. Modular dual mobility (MDM) implants incorporate a metal liner (e.g. cobalt-chromium alloy) in a metal shell (e.g. titanium alloy), raising concern for mechanically assisted crevice corrosion at the modular liner-shell connection. We sought to examine fretting and corrosion on MDM liners, to analyze the corrosion products, and to examine histologically the periprosthetic tissues.

Methods

A total of 60 retrieved liners were subjectively scored for fretting and corrosion. The corrosion products from the three most severely corroded implants were removed from the implant surface, imaged using scanning electron microscopy, and analyzed using Fourier-transform infrared spectroscopy.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 94 - 94
1 Mar 2008
Schemitsch E Togawa D Reid J Bauer TW Sakai H Hawkins M Dimaano F
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The purpose of this study was to evaluate trabecular bone response, at fifty-two week follow-up, to four different synthetic graft materials (CaSO4 and CaSO4 – HA/TCP composites) as compared to autograft in a canine defect model. The group with the highest HA/ TCP proportion had the greatest amount of residual graft material and total mineralized material. Increasing the proportion of HA/TCP reduces the rate of dissolution, and appears to have little effect on bone formation at long term follow-up. This study further suggests that a range of composites could be created to match the spectrum of resorption rates demanded by clinical applications.

The purpose of this study was to evaluate trabecular bone response to four synthetic graft materials (CaSO4 and CaSO4 – HA/TCP composites) as compared to autograft in a canine defect model, at long term follow-up.

Both 85% CaSO4 – 15% HA/TCP and 65% CaSO4 – 15% HA/TCP showed bone formation similar to autograft. The group with the highest proportion of HA/TCP lasted longer than the other formulations. The results suggest that increased HA/TCP proportions reduce the rates of dissolution, without compromising bone formation in the current model.

Results suggests that a range of composites could be created to match the spectrum of resorption rates demanded by clinical applications.

In this REB-approved RCT, bilateral humeral and femoral cylindrical defects were filled with one of four types of pellets with varying proportions of CaSO4 – HA/TCP, autograft bone, or left unfilled. After sacrifice at six, twelve, twenty-six or fifty-two weeks, defect sites were evaluated histologically for tissue and inflammatory response, area fractions of residual graft material, and bone ingrowth in the defects.

The area of the defect occupied by residual graft material in the group with the highest percentage of HA/TCP was greater than in other composite groups (p< 0.0001). This group contained the greatest amount of total mineralized material (graft material + bone) (p< 0.03. The extent of new bone formation increased from twelve to twenty-six weeks (p< 0.0001). Both 85% CaSO4 – 15% HA/TCP and 65% CaSO4 – 15% HA/TCP showed bone formation similar to autograft.

Funding: Research grant from Stryker Howmedica, Matwah, NJ.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 436 - 436
1 Apr 2004
Bauer TW Takikawa S Togawa D
Full Access

The results of wear testing using hip simulators have suggested that highly cross-linked polyethylene (PE) is more resistant to abrasive wear than “conventional” polyethylene that has been sterilized by 2.5 – 4 Mrad of radiation. Optimum methods for testing other mechanical properties of PE are controversial, but some studies have suggested that highly cross-linked polyethylenes have reduced impact strength when compared to either “conventional” PE or PE that has never been cross-linked. T he principle mechanism of loosening of most total hip prostheses is bone loss induced by debris particles that have been generated by abrasive wear, hence the rationale for using highly cross-linked PE for total hip arthroplasty. The principle mechanism of failure of bipolar hips, however, is less clear. If abrasive wear is important in bipolars, then the use of highly cross-linked PE is reasonable, but if impingement is an important complication of bipolar arthroplasty, then the use of highly cross-linked polyethylene might We revewied the implant registry of the Cleveland Clinic and identified 62 retrieved bipolar implants. The peripheral rim of each was evaluated, and a previously published scoring system used to grade the extent of rim damage due to impingement. A subset of implants were disassembled, and the shadowgraph method was used to measure the extent and rate of polyethylene abrasive wear. Adequate clinical information and radiographs were available in relatively few cases, but when available, the results of implant evaluation were correlated with clinical and radiographic findings.

The results suggest that both abrasive wear and rim damage due to impingement are common findings in retrieved bipolar devices. Further studies with better clinical and radiographic correlation are needed to clarify the most significant factors with respect to osteolysis and implant failure, but our results suggest caution in implementing highly cross-linked polyethylene for bipolar devices.


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 6 | Pages 901 - 909
1 Aug 2000
Böhler M Mochida Y Bauer TW Plenk H Salzer M

We compared wear particles from two different designs of total hip arthroplasty with polycrystalline alumina-ceramic bearings of different production periods (group 1, before ISO 6474: group 2, according to ISO 6474). The neocapsules and interfacial connective tissue membranes were retrieved after mean implantation times of 131 months and 38 months, respectively. Specimen blocks were freed from embedding media, either methylmethacrylate or paraffin and digested in concentrated nitric acid. Particles were then counted and their sizes and composition determined by SEM and energy-dispersive x-ray analysis (EDXA).

The mean numbers and sizes of most alumina wear particles did not differ for both production periods, but the larger sizes of particle in group 1 point to more severe surface destruction. The increased metal wear in group 2 was apparently due to alumina-induced abrasion of the stems. In this study the concentrations of particles in the periprosthetic tissues were 2 to 22 times lower than those observed previously with polyethylene and alumina/polyethylene wear couples.


The Journal of Bone & Joint Surgery British Volume
Vol. 80-B, Issue 4 | Pages 745 - 745
1 Jul 1998
BAUER TW