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Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 381 - 381
1 Jul 2011
Munro J Shim V Anderson I Pitto R
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Aseptic loosening is the leading cause for revision in total hip arthroplasty. Retro-acetabular lysis is often a silent process until severe bone loss causes catastrophic failure. This presents a technically difficult problem for the surgeon and a poorer result for the patient compared to primary arthroplasty. While the major cause of osteolysis is reaction to polyethylene particles, there is little data on the initiation and progression of such lesions. Further, alterations in the mechanical environment caused by such pathology is unclear. We present our use of 3D, finite element (FE) models of retro-acetabular pathology to investigate the biomechanical effects of osteolysis in total hip arthroplasty. Axial CT scan slices from a patient with cystic osteolysis were selected. Areas of cortical bone, cancellous bone, the cup and the cyst are accurately identified. The axial images are matched to a predetermined grid and used to build a complex finte element model. In this way complex anatomy can be built into the FE model and used to map cystic lesions. Force is then applied to the acetabulum.

Initial analysis shows similar stress transmission in cystic disease compared to the post operative pelvis. Pelvic bone still behaves as a sandwich construct with transmission from the acetabulum to the SI joints, pubic symphysis and medial wall. In the setting of pelvic medial wall deficiency, stress transmission is altered with areas of low stress around the defect.

The FE models containing pathology can be compared to models with generic bone density values immediately after total hip arthroplasty. The presence of a cyst in cancellous bone with intact cortical bone, demonstrates strain patterns similar to the post operative pelvis. Once cortical bone loss occurs strain patterns begin to change. This may mark a critical point in osteolytic progression. We present a developing new tool to be used in the assessment of a patient population with retroacetabular cystic disease.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 381 - 381
1 Jul 2011
Segar A Malak S Anderson I Pitto R
Full Access

Correct positioning of the femoral component in resurfacing hip arthroplasty (RHA) is an important factor in successful long-term patient outcomes. Computer-assisted navigation (CAS) shows potential to improve implant positioning and possibly prolong survivorship in total hip and knee arthroplasty. The purposes of CAS systems in resurfacing the femoral head are to insert the femoral head and neck guide wire with greater accuracy and to help in sizing the femoral component, thus reducing the risk of notching of the head and neck junction. Several recent studies reported satisfactory precision and accuracy of CAS in RHA. However, there is little evidence that computer navigation is useful in the presence of anatomical deformities of the proximal femur, which is frequently observed in young patients with secondary degenerative joint disease.

The purpose of this in-vitro study was to determine the accuracy of an image-free resurfacing hip arthroplasty navigation system in the presence of two femoral deformities: pistol grip deformity of the head and femoral neck junction and slipped upper femoral epiphysis deformity. An artificial phantom leg with a simulated hip and knee joint was constructed from machined aluminum. Implant-shaft angles for the guide wire of the femoral component reamer were calculated, in frontal and lateral planes, with both a computer navigation system and an electronic caliper combined with micro-CT.

With normal anatomy we found close agreement between the CAS system and our measurement system. However, there was a consistent disagreement in both the frontal and lateral planes for the pistol grip deformity. Close agreement was found only on the frontal plane angle calculation in the presence of the slipped upper femoral epiphysis deformity, but calculation of the femoral head size was inaccurate.

This is the first study designed to assess the accuracy of a femoral navigation system for resurfacing hip arthroplasty in the presence of severe anatomical deformity of the proximal femur. Our data suggests CAS technology should not be used to expand the range of utilisation of resurfacing surgery, but rather to improve the surgical outcome in those with suitable anatomy.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 202 - 202
1 Mar 2010
Anderson I Shim V Pitto R Malcolm D Mithraratne K Hunter P
Full Access

Patient- specific orthopaedic models are currently used in computer navigation. They provide realistic 3-D geometries for assessment of device placement (e.g. tibial trays, hip implants). Models are generated at time of operation by the surgeon. But patient-specific models have other uses. We envisage a future in which realistic 3-D patient models are routinely used for predicting the outcome of surgical procedures and new devices and for general patient health monitoring.

We are currently developing accurate 3-D models directly from CT scan post-operation. They are being used in investigations of the progress of bone remodeling. Such work can provide valuable feedback on the outcome of new procedures and how bone remodels under load. Such models would eventually include other tissue such as muscles and skin.

But there are a number of research and development challenges associated with the creation of patient-specific models. They include

minimal use of radiation for data collection;

need for an automated method of generating patient specific models as clinicians (not engineers) should be able to create computer models easily and quickly;

need for improvements in computational efficiency. An ultimate goal would be to run simulations on computer hardware that is available to the clinician;

How to deal with missing data. We need techniques for supplementing patient data with data from a “model library”;

Research to provide techniques for dealing with multiple organs (muscles, skin and bone altogether).

We are working to meet these challenges. They include the use of generic data to supplement patient data, efficient ways of morphing models to fit the patient, and multi-scale modeling strategies. Work in progress at the Auckland Bio-engineering Institute will be presented in this talk.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 166 - 166
1 Mar 2010
Clarke I Lazennec Y Cattonne Y Kubo K Anderson I McPherson E Donaldson T
Full Access

FDA approval of metal-on-metal (MOM: 28, 32mm) bearings has provided 10 years of clinical experiences in USA. However there has been no detailed mapping of wear phenomena in retrieval cases. We present an analysis of 28 cases, MOM retrievals with 1 to 10 years follow-up, radiographic reviews and metal ion studies. Ball diameters ranged from 28mm to 42mm. Two balls were the early design with skirts. Main indicators for revision were the progressive radiographic changes indicative of osteolysis, with associated hip pain. Approximately 54% of patients were males and ages ranged from 36 to 76 years of age. Only 7 femoral stems were recovered but all had impingement marks. Only three cases lacked any evidence of stripe wear and these were in very elderly patients. Approximately 85% of these cases showed some evidence of stripe wear and multiple stripes were clearly visible on 50% of the femoral balls. The medial ball stripes were twice as common as lateral. Stripe wear was identified in 25% of CoCr liners.

In the hip simulator studies generally show ‘run-in’ wear rates of 1–7mm3 per million cycles (Mc). We noted that above the 5mm3/Mc threshold, the serum generally appeared black. In contrast, the ‘steady-state’ wear rates of 0.1–1.6 mm3/Mc showed the true potential of MOM bearings. However there were often examples of higher wear (7–20 mm3/Mc), which gave confounding trends in published studies. Our studies of metal ions in the simulator lubricant provided a very accurate representation of MOM wear.

There are many limitations in comparing in-vitro to in-vivo wear performance. Our retrieval data are biased to cases that failed due to hip pain, had radiographic signs of progressive osteolysis and some showed high levels of metal ions. There was also the bias of having predominantly a CoCr sandwich design (polyethylene adaptor). Use of the small ball added the well-known risks of impingement, subluxation and dislocation with rigid cups. Using the ‘damage modes’ from McKellop, we found only normal Mode-1 wear to be rare in these cases, whereas Modes# 2–4 had an incidence approaching 30% each. Signs of impingement were evident in 85% of our cases. Thus summarizing these MOM wear phenomena in retrieved 28mm sandwich cups, the evidence implicated impingement and 3rd-body wear modes (#2–4) as the clinical risk for adverse wear effects at 10 years follow-up. The in-vitro wear studies have not yet simulated such adverse clinical effects.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 154 - 154
1 Mar 2010
Clarke I Kubo K Lazennec Y Cattonne Y Anderson I Smith E Turnbull A Donaldson T
Full Access

From 1985 metal-on-metal (MOM) designs of resurfacing (RSA) and total hip arthroplasties (THR) have been available over a large diameter range (28–60mm). In-vitro studies indicated satisfactory low wear performance for all designs and diameters tested (wear = 0.1 to 7 mm3). While reports from many centers have been encouraging, some have reported adverse effects. We reviewed clinical and metal ion studies in large diameter retrievals and compared these to 28mm MOM cases. Patients with the latter THR ranged 36–76 years of age and were followed 9–11 years. Main finding in our revisions was osteolysis and pain. The 28mm ball was represented 86% of cases; 71% balls had stripe wear. For liners, 25% had circumferential stripe wear and impingement was evident in 64% cases. Seven cemented stems were recovered with impingement marks; 26 stems were undamaged and therefore not revised. Using the concept of ‘damage modes’ from McKellop, normal wear mode #1 was evident in only 14% of 28mm retrievals whereas incidence of ‘abnormal’ modes #2-4 approached 30% each. Thus the 28mm MOM appeared susceptible to impingement risks with CoCr liners. Summarizing MOM retrievals, damage modes 2–4 were most likely implicated in revisions. The performance of such ‘small diameter’ THRs will be contrasted to our large diameter THR and RSA experience. The questions to be reviewed include, how much of the reported MOM adversity was predictable and how much risk was due to

wear of small diameter MOM,

adverse cup positioning and hip instability,

cup-stem impingement issues or

design conformity issues?


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 340 - 340
1 May 2009
Chou J Anderson I Astley T Poon P
Full Access

Reverse total shoulder replacement is a viable surgical option for Cuff Tear Arthropathy. Short term results have been promising. Longer term follow-up has demonstrated a high rate of scapular notching. This is attributed to mechanical impingement between the humeral cup and scapular neck when the arm is fully adducted. The long term sequelae of scapular notching are unclear but there is concern that it may compromise fixation of the glenoid component and affect functional outcomes.

Design modifications to address this problem include the newly available eccentric glenospheres and larger diameter glenospheres. These glenospheres are designed to offer greater ranges of motion and theoretically may reduce the risk of impingement and notching. The purpose of this biomechanical study is to demonstrate the difference in range of motions with each design of glenosphere. To our knowledge there is no published literature evaluating this design differences.

The SMR (Lima Orthotec) reverse total shoulder prothesis was implanted into a synthetic bone model (Sawbones, Pacific Laboratories, Vashon, Washington). Four different types of glenospheres (Standard 36 mm, Eccentric 36 mm, Standard 44 mm, Eccentric 44 mm) were then implanted into the same model which was fixed on a measurement table. The precision coordinate measurement device (FARO-Arm, SO6/Rev22, FARO Technologies Inc., Lake Mary, Florida) was used to establish the centres of rotation and ranges of motion.

To date, the collection of data has just been completed, but the data are yet to be analysed. In conclusion, this is a biomechanical study evaluating the ranges of motion and risk of notching, comparing different designs of glenospheres in Reverse Total Shoulder Joint Replacement.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 352 - 352
1 May 2009
Graydon A Pitto R Malak S Anderson I
Full Access

Implant malposition remains one of the common causes of total knee replacement (TKR) failure and increased wear. Recent advances in computer technology have made available navigation systems for TKR and other orthopaedic procedures. The purpose of our study was:

to develop a method to assess the accuracy of an image-free TKR navigation system;

to assess its accuracy in a leg with normal or near-normal mechanical axis;

to assess its accuracy in a leg with abnormal mechanical axis.

The system chosen was an image-free system based on electromagnetic technology, the MedTronic AxiEM TKR navigation system. To facilitate measurements, an artificial leg (phantom) was constructed from machined Plexiglas with simulated hip and knee joints. Additional joints located at the midshaft of the tibia and femur allowed deformation in the flexion/extension (y), varus/valgus (x) and rotational (z) planes. Using a highly accurate digital calliper unit (FaroARM Technologies, USA) to precisely measure co-ordinates with pre-machined points on the phantom, a software program was developed to convert these local co-ordinates into a determination of actual leg alignment. This technique was verified using repeated measurement with variable coordinates, giving accuracy to within 0.05 of a degree.

Simulated procedures were then performed with both normal and abnormal leg mechanical axis. At specific points in the procedure, information was compared between the FaroARM digital measurements and the CAS system. Repeated serial measurements were undertaken. In the setting of normal alignment, accuracy to within one degree was demonstrated. In the setting of abnormal x, y and z plane alignment in both femur and tibia, accuracy to within two degrees was demonstrated.

Several clinical studies have been performed to assess the precision of computer navigation in TKR. This study was designed to assess the accuracy of a clinically validated navigation system. The study demonstrates the high level of in-vitro accuracy of the MedTronic AxiEM navigation system in both normal and abnormal mechanical leg alignment settings.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 352 - 352
1 May 2009
Malak S Anderson I Pitto R
Full Access

Implant malposition is one of the most common causes of failure in resurfacing arthroplasty of the hip (RAH). Recent advances in computer technology have made available navigation systems for RAH and other orthopaedic procedures. The purpose of our study was:

to develop a method to assess the accuracy of an image-free RAH navigation system;

to assess its accuracy in a leg with normal anatomy and with deformity of the proximal femur.

We used the Ci-CAS RAH navigation system (DePuy - BrainLab). To facilitate measurements, an artificial leg (phantom) was constructed from machined aluminium with simulated hip and knee joints. The hip and knee articulating surfaces were synthetic bone material (Sawbones – Pacific Laboratories). An additional joint located at the trochanteric region allowed deformation in varus/valgus and ante/retroversion of the head/neck segment. Using a highly accurate digital calliper unit (FaroARM Technologies, USA) to precisely measure co-ordinates with pre-machined points on the phantom, a software program was developed to convert these local co-ordinates into a determination of actual anatomy and leg alignment. This technique was verified using repeated measurement with variable co-ordinates, giving accuracy to within 0.05 of a degree.

Simulated procedures were performed with both normal and abnormal anatomy of the proximal femur. At specific points in the procedure, information was compared between the FaroARM digital measurements and the Ci-CAS system. Repeated serial measurements were undertaken. In the setting of normal alignment, accuracy to within 0.5 degrees was demonstrated. In the setting of abnormal alignment (varus/valgus and ante/retroversion) of the proximal femur, accuracy to within 2 degrees was demonstrated.

To our knowledge, this is the first study to assess accuracy of a RAH navigation system. The study demonstrates a satisfactory level of accuracy for the Ci-CAS in both normal and abnormal anatomical settings. Currently, no international standard or methodology exists against which these results can be compared. In the near future, introduction of new navigation technologies will make crucial the development of international standards for pre-clinical validation of computer-assisted navigation systems. The present study is a first attempt to address this issue.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 353 - 353
1 May 2009
Shim V Pitto R Streicher R Anderson I
Full Access

A number of densitometry studies have reported dramatic density losses in the acetabular region after uncemented Total Hip Arthroplasty (THA)1,2. However the mechanical implication of such loss is not yet known. This study aims to perform a mechanical analysis with patient specific Finite Element (FE) models to find out how the stress distribution affects the Bone Mineral Density (BMD) changes after uncemented THA.

An existing patient CT dataset collected for a densitometry study was used to generate patient-specific FE models with a previously validated FE mesh generation method3. Boundary and loading conditions included the hip joint force and the forces of 21 muscles attached to the pelvic bone at eight characteristic phases of a gait cycle 4. Tensile and compressive components of principal stresses were calculated after each simulation.

In general, both compressive and tensile principal stresses decreased after uncemented THA but the magnitude of decrease for tensile stresses was much greater than compressive stresses. The changes in tensile stresses were matched with BMD loss patterns. In particular, the densitometry study revealed that areas dorsal to the prosthesis lost more bone density than areas ventral to the prosthesis1. The stress distribution pattern showed that such areas experienced high tensile stress initially and then a dramatic decrease in their magnitude while their compressive stresses remained relatively unchanged. On the other hand, the regions where BMD was maintained - the areas superior to the cup - experienced high compressive stresses initially, which remained relatively high three years after the surgery.

Although it is a result from one patient, results suggest that changes to tensile and compressive stresses might influence BMD differently after uncemented THA. Our hypothesis is that regions with high tensile stress experience bone loss while BMD of the regions with high compressive stress are maintained. More patient datasets are being processed to test this hypothesis. Findings from this study can explain the phenomena of retroacetabular osteolysis, late migration and implant failure of press-fit cups observed in long-term clinical studies.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 344 - 344
1 May 2009
Blyth P Stott N Peters I Anderson I
Full Access

Cannulated screw fixation is currently the treatment of choice for slipped capital femoral epiphyses (SCFE). A SCFE module of the Bonedoc simulator was created in order to test the ability of advanced trainees to place the screw in the correct position, and the practicality of using the simulator within the orthopaedic surgery training curriculum.

Bonedoc (University of Auckland) is a virtual reality simulator of image guided orthopaedic operations1. This simulator runs in Internet Explorer (Microsoft, USA) using the Octaga (Octaga, Norway) plugin. The total download is around 4 MB. The SCFE module was created from a CT scan of a Grade 2 acute on chronic SCFE. DICOM images were imported into 3DView (www.rmrsystems.co.uk) and a mesh created. The generic femur from the DHS module was morphed within the CAD package Blender (Blender.org) to conform to this reconstructed SCFE mesh.

Forty two advanced trainees operated on the same virtual SCFE during a training weekend. The trainees had 25 minutes to become familiar with the simulator and complete the operative case. The trainees performed all tasks relevant to the operation. At the operation’s conclusion the trainees self-assessed their performance. Subsequently the simulator provided surgically relevant objective feedback on aspects such as exact position of the screw, misplaced attempts and the number of x-rays. The results were analysed using SAS (SAS Institute, USA) in subgroups based on year on the scheme, as well as correlated within each operation.

There was no difference in the accuracy with which the virtual slipped capital femoral epiphysis was pinned by trainees in different years in the training programme. However, 26 of the 39 of the virtual screws were placed in the superior direction. There was no correlation between number of X-ray images taken and final accuracy of screw placement. The number of misplaced drill holes was correlated both with number of X-ray images taken (p< 0.01) and operative time (p< 0.01) but not with final accuracy of the screw. An increase in misplaced attempts was correlated with angulation errors in the anterior plane (p< 0.01). There was no correlation between the trainees’ self assessment and any of the measured variables.

The Bonedoc simulator provides a means to test trainees on technical aspects of a surgical procedure. It provides objective results, which can mimic real world outcomes. In addition, the ability to test all trainees on the same virtual operative case allows standardisation of assessment. All trainees completed the task to a similar level of accuracy, which may reflect the overall skill level in advanced trainees within the New Zealand. However, many trainees placed the screw in the superior portion of the femoral head, which is thought to increase the risk of avascular necrosis2. Further work is required to evaluate how accurately performance on the simulator predicts performance in the operating theatre


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 350 - 350
1 May 2009
Oberhofer K Mithraratne K Stott S Walt S Anderson I
Full Access

Cerebral palsy (CP) results from an injury to the immature brain; and it leads to progressive musculoskeletal (MS) impairment in most affected patients. Orthopaedic surgery involving muscle-tendon lengthening is a method for managing short muscles in CP patients. Knowledge of muscle length prior to surgery is beneficial to surgical success. However, using common assessment methods like 3D gait analysis or physical examination, accurate pre-surgery estimation of muscle lengths during walking is difficult.

Computer models of the lower limbs, which provide more insight into muscle functioning during walking, have become increasingly important within the research field of CP. MS models are commonly driven by joint kinematics from clinical gait analysis. The most often used MS model in CP related research is based on the geometry of an adult human man with muscles modelled as line segments. This approach might be reasonable for small muscles with well-defined paths; however, for long muscles with multiple attachment points and curved paths, a more realistic 3D muscle model is required.

The aim of this study is the development of a clinical assessment tool for CP patients by incorporating kinematic data from gait analysis into a 3D finite-element MS model of the lower limbs. Ethical approval has been obtained to develop subject-specific MS models of 12 children with CP and 12 control children (age 8 – 12 years) based on magnetic resonance images. Kinematic data from 3D gait analysis is used as input data to transform the bony structures. Soft-tissue muscle deformation is modelled according to a variant of free-form deformation called the Host-Mesh Fitting Technique. So far, MS models of the lower limbs of three control children and of one child with CP were developed. The resulting muscle length changes during walking agree reasonably well with published data. The proposed modelling approach together with the library of 24 MS models will enable us to develop a powerful tool to investigate gait of children with CP.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 342 - 342
1 May 2009
Mutu-Grigg J Malak S Anderson I Cullen J
Full Access

The goal of this study was to determine which of two techniques for the treatment of peri-prosthetic femoral shaft fractures has the greatest torsional integrity. The study designed was a laboratory study, using 13 matched pairs of embalmed femurs. The femurs were implanted with a cemented total hip prosthesis, with a transverse osteotomy distal to the stem. These fractures were fixed either with a metal plate with three proximal unicortical screws and three distal bicortical screws or with three proximal cables and three distal bicortical screws. The fracture fixation was tested to failure in torsion. The pattern of failure and torsional limits were recorded.

There was no significant difference to failure level between the two constructs. Failure with the proximal unicortical screws was usually catastrophic versus non-catastrophic with proximal cables. The femurs were significantly more likely to fracture in internal rotation.

Treatment with proximal cables has the same load to failure in torsion but significantly less complications than with unicortical screws, in agreement with the literature. The findings of the construct being weaker in internal rotation, appears to be a new finding and an area of possible new research.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 352 - 352
1 May 2009
Munro J Shim V Pitto R Anderson I
Full Access

Long term clinical follow-up of total hip arthroplasty (THA) has identified problems associated with cyst formation. Such cysts are formed as a result of expansile osteolysis, which starts on a small area of the skeleton and spreads into the bone away from the surface of the prosthesis. Since large areas of the prosthesis are still in immediate contact with the skeleton the prosthesis is not loose and the patients are usually without pain. However this form of osteolysis may destroy large areas of the skeleton before it is detected and result in a sudden fracture due to a weakened skeleton. While there are some short term prospective trials that have shown changes in bone density in the periacetabular region, one needs a biomechanical model to understand factors that influence bone remodeling leading to cyst formation. This study aims to develop a mathematical model for studying the mechanical effects of bone cysts in the acetabulum of THA patients.

2D finite element (FE) models of patients with known restroacetabular cystic disease were generated using coronal CT images from the central region of the acetabulum. The boundary between bone and soft tissue was segmented and an FE model generated. Mesh convergence tests were performed to identify a suitable level of mesh refinement. Three material zones representing– cortical bone (E=17GPa), cancellous bone (E=1GPa) and a titanium cup (E=120GPa) – were included in the model. A series of simulations were run to investigate how cysts affect stress distribution as well as the mechanical consequence of medial wall deficiency.

The presence of a cyst did not alter the pattern of stress distribution in the lateral and medial wall. But the strain energy function increased significantly at the inferior margin of the cyst within its cancellous bone. This may encourage bone formation at the cyst margin and help to explain the sclerotic walls seen in some cysts. Models with absent medial walls showed that both compressive and tensile stresses lowered in the cortical wall and the strain energy function reduced almost to zero. This suggests that a medial wall defect has a high risk of progression.

The current 2D model cannot incorporate complex acetabular geometry or complex forces acting on the hip. Therefore the current model will be further developed into a 3D FE model of the whole pelvis that also represents the pelvic ring structure more adequately. Physiologically meaningful boundary conditions as well as patient specific geometry and material properties will be used to investigate mechanical effects of bone cysts realistically.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 155 - 155
1 Mar 2008
Shim V Anderson I Rossaak M Streicher R Pitto R
Full Access

In recent years, some attempts have been made to develop a method that generates finite element (FE) models of the femur and pelvis using CT. However, due to the complex bone geometry, most of these methods require an excessive amount of CT radiation dosage. Here we describe a method for generating accurate patient-specific FE models of the total hip using a small number of CT scans in order to reduce radiation exposure.

A previously reported method for autogenerating patient-specific FE models of the femur was extended to include the pelvis. CT osteodensitometry was performed on 3 patients who had hip replacement surgery and patient-specific FE models of the total hip were generated. The pelvis was generated with a new technique that incorporated a mesh morphing method called ‘host mesh fitting’. It used an existing generic mesh and then morphed it to reflect the patient specific geometry. This can be used to morph the whole pelvis, but our patient dataset was limited to the acetabulum. An algorithm was developed that automated all the procedures involved in the fitting process.

Average error between the fitted mesh and patient specific data sets for the femur was less than 1mm. The error for the pelvis was about 2.5mm. This was when a total 18 CT scans with 10mm gap were used – 12 of the femur, and 6 of the pelvis. There was no element distortion and a smooth element surface was achieved.

Previously, we reported a new method for automatically generating a FE model of the femur with as few CT scans as possible. Here we describe a technique that customizes a generic pelvis mesh to patient-specific data sets. Thus we have developed a novel hybrid technique which can generate an accurate FE model of the total hip using significantly less CT scans.

An automated method of generating FE models for the total hip with reduced CT radiation exposure will be a valuable clinical tool for surgeons.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 155 - 155
1 Mar 2008
Shim V Anderson I Rossaak M Streicher R Pitto R
Full Access

In recent years, some attempts have been made to develop a method that generates finite element (FE) models of the femur and pelvis using CT. However, due to the complex bone geometry, most of these methods require an excessive amount of CT radiation dosage. Here we describe a method for generating accurate patient-specific FE models of the total hip using a small number of CT scans in order to reduce radiation exposure.

A previously reported method for autogenerating patient-specific FE models of the femur was extended to include the pelvis. CT osteodensitometry was performed on 3 patients who had hip replacement surgery and patient-specific FE models of the total hip were generated. The pelvis was generated with a new technique that incorporated a mesh morphing method called ‘host mesh fitting’. It used an existing generic mesh and then morphed it to reflect the patient specific geometry. This can be used to morph the whole pelvis, but our patient dataset was limited to the acetabulum. An algorithm was developed that automated all the procedures involved in the fitting process.

Average error between the fitted mesh and patient specific data sets for the femur was less than 1mm. The error for the pelvis was about 2.5mm. This was when a total 18 CT scans with 10mm gap were used – 12 of the femur, and 6 of the pelvis. There was no element distortion and a smooth element surface was achieved.

Previously, we reported a new method for automatically generating a FE model of the femur with as few CT scans as possible. Here we describe a technique that customizes a generic pelvis mesh to patient-specific data sets. Thus we have developed a novel hybrid technique which can generate an accurate FE model of the total hip using significantly less CT scans.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 166 - 166
1 Mar 2008
Graydon A Malek S Anderson I Pitto R
Full Access

The correct positioning of implant components in total knee replacement (TKR) is important for a successful long-term outcome. In order to address the problems inherent with conventional alignment methods, several computer-assisted navigation systems (CAS) have been developed. Despite numerous reports of clinical outcomes and system reliability, there is a lack of studies independently evaluating the precision and accuracy of such systems. We report on the design and development of a method and device to evaluate the accuracy of such a computer-assisted navigation system in two situations; 1) Normal or near-normal lower limb mechanical axis, and 2)Simulated femoral and/or tibial extra-articular deformity in either varus/valgus (x), internal/external rotation (y) or flexion/extension (z) planes.

The system assessed was the Ci Knee-CAS navigation system (BrainLab/De Puy). This image-free system requires the registration of specific anatomical points to identify the mechanical axis of the lower limb and therefore provide information on resection level and alignment. In order to precisely measure and accurately reproduce these points we constructed a phantom device along anatomical guidelines, with lockable joints located at the mid-shaft of both femur and tibia. We then identified geometric CAS data; 1) Tibial resection height, and 2) Tibial resection plane, and using specially written software compared this against validated co-ordinate measurements independently obtained by a FaroArm co-ordinate measurement system (FARO Technologies, USA). This enabled data from the navigation system to be directly compared against highly accurate reference measurements.

Accuracy of the system was then assessed with both normal mechanical alignment of the lower limbs and simulated extra-articular deformity.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 320 - 320
1 May 2006
Blyth P Stott NS Anderson I
Full Access

There is increasing pressure to develop virtual reality surgical simulation that can be used in surgical training. However, little is known of the attitudes of the surgical community towards such simulation, and which aspects of simulation are most important.

A postal survey on attitudes to surgical simulation was sent to all New Zealand orthopaedic surgeons and advanced trainees. This comprised 44 questions in ten sections, using either a visual analogue scale (0 to 10) or free text box replies. Results were analysed for two sub-groups; surgeons qualified before 1990 and those qualified in or after 1990 or still in training.

Of 208 possible responses, 142 were received, a response rate of 68%. Only 4 respondents had tried a surgical based simulator. Earlier qualified surgeons were more likely to agree that simulation was an effective way to practice surgical procedures, median score 7.7 versus 5.6 (p=0.03). Both groups thought the most important task for simulation was practicing angulation/spatial orientation (median score 8.4/10), while a realistic view of the operation was the most important requirement (median score 9/10). Both groups were unconvinced that simulation would impact on their practice in the next five years, with this statement being scored lower by later qualified surgeons, median score 2.4 versus 4.1 (p=0.04).

Orthopaedic surgeons in New Zealand are supportive of surgical simulation but do not expect simulation to have an impact in the near future. Intriguingly, later qualified surgeons and trainees are more sceptical than their earlier qualified colleagues.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 364 - 365
1 Sep 2005
Shim V Anderson I Faraj S Pitto R
Full Access

Introduction and Aims: CT is one of the most versatile and useful medical imaging modalities for computer assisted surgery (CAS) and monitoring bone remodelling. However, the high radiation dosage hinders its widespread use. We describe a method for generating smooth and accurate Finite Element (FE) meshes using CT data with reduced radiation exposure.

Method: We have performed serial CT assisted osteodensitometry measurement on seven patients who had a total hip replacement. FE models were generated automatically with cubic Hermite basis functions for both geometry and density. The meshes were fitted to the geometric and density data sets using least square’s fitting. Density was displayed over the surface of the elements using a colour spectrum. The effect of reducing radiation dosage was studied by generating five different types of FE meshes from each patient with different numbers of CT slices. The different mesh types were generated by varying the gap between slices.

Results: The mesh with the smallest number of CT slices used seven CT scans, with the gap between slices of 3cm on average while the mesh with the largest number of slices used 22 scans with the gap of 0.8cm. For the mesh with the largest number of CT slices, the average error after the geometric fitting was less than 0.5mm. The average error for the density fitting was 70.2 mg/ml. When expressed as the percentage to the overall density data range (0 ~ 1500 mg/ml), the average error was 4.7%. Meshes generated with a smaller number of CT slices had larger errors, and this increased as the number of slices used decreased. The error in geometry dropped dramatically (more than 50%) when more than 10 slices were used, whereas the error in density decreased approximately linearly as the number of slices increased. Overall, it was possible to generate realistic and smooth meshes with a geometrical error of less than 1.5mm and a density error less than 7% using 10 CT slices.

Conclusion: One strength of the current study is that we have used cubic Hermite elements, which requires much less information in generating FE meshes without sacrificing too much accuracy. Our study has shown that we can generate realistic and smooth meshes with about 10 CT slices of the proximal femur. This is important to enhance the power of CT in clinical applications.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 27 - 27
1 Mar 2005
Anderson I MacDiarmid A Malak S
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Bone autograft contains living cells that participate in the healing process. Fragmentation and heat production during cutting will kill cells. We have investigated how excessive graft fragmentation and heating can be avoided.

Two prototype cutters were fabricated. Each had a single cutting edge at the front end of a 12 mm diameter collection barrel. The principal difference between the cutters was the rake angle (at the cutting edge): 23° on cutter #1 and 45° on cutter #2.

Thrust load, feed-rate, and torque were measured using an instrumented drill press. A total of 58 tests on specimens of fresh bovine cancellous bone (distal femur, ex-abattoir) and medium density polyurethane foam (Sawbones, WA. USA) (density 252 kg/m3) were conducted: twenty-four at 100 rpm and thirty-four at 200 rpm.

Small flake-like fragmented bone chips were encountered at low thrust loads. As thrust load was increased the chips became thicker. The average cutting energy for bone was 43.7 Nm (s.d. 48.2 Nm) for cutter 1 and 37 Nm (s.d. 27 Nm) for cutter 2. The average cutting energy for the foam was 13.9 Nm (s.d. 6.0 Nm) for cutter 1 and 8.1 Nm (s.d. 3.0 Nm) for cutter 2. Polyurethane results showed a similar trend.

A higher rake angle on a bone graft tool is associated with a lower cutting energy. In turn, a lower cutting energy will generate a lower temperature in the graft, a result that is beneficial for cell survival. Graft tool design can also influence bone chip size. These experimental results are being used for the development of cell-friendly tooling.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 27 - 27
1 Mar 2005
Shim V Anderson I Pitto R
Full Access

Periprosthetic bone density (BD) changes can be tracked using computed-tomography (CT) assisted osteodensitometry. Patient-specific computer-generated models allow for good visualisation of density changes in bone. We describe techniques for generating smooth and realistic finite element (FE) models that contain both BD and geometry from quantitative CT data using cubic Hermite elements.

FE models were created for three patients who had a total hip replacement. CT-scans were performed at 10 days, one year, and 3 years after the operation and calibrated using a synthetic hydroxyapatite phantom. FE models of the proximal femur were automatically generated from the CT data. Each model had on average 300 tri-cubic Hermite elements. Models were least squares fitted to the entire dataset. BD data was also sampled and fitted using the same cubic interpolation functions. Density was displayed using a colour spectrum.

Realistic patient-specific FE models were obtained. Density and changes in BD were easy to identify. The error in the geometric fitting (RMS distance between data points and the model surface) was generally less then 0.5 mm. The average error for the density fitting (RMS difference between each density data point and the interpolation function value at the same point) was 61.64 mg/ml or 3.08%.

CT osteodensitometry’s potential use as a clinical tool for monitoring changes to BD can be significantly enhanced when used in conjunction with realistic patient-specific finite element (FE) models. Realistic models can be generated with an economic use of scan data, thus keeping radiation dosage down.