School of Mechanical Engineering, University of Birmingham, Birmingham, UK. This study investigated the effects on friction of changing the dimensions of a ball-and-socket Total Disc Arthroplasty (TDA). A generic ball-and-socket model was designed and manufactured based on the dimensions and geometry of a metal-on-metal Maverick (Medtronic, Minneapolis, USA) device. Keeping the radial clearance similar to the Maverick, the ball and socket dimensions varied between 10 to 16 mm and 10.015 to 16.015 mm, respectively, in order to enable the comparison between different dimensions. The implants were made out of Cobalt Chrome Molybdenum alloy, with a surface roughness of 0.05 μm. A Bose spine simulator (Bose Corporation, ElectroForce Systems Group, Minnesota, USA) was used to apply an axial compressive force to the TDA. Axial rotation of ±2° was then applied at various frequencies and the resulting frictional torque measured. The tests were performed under an axial load of 50, 600 and 1200 N and frequencies of 0.5, 1.0, 1.5 and 2.0 Hz, for four different samples of radii 10, 12, 14 and 16 mm (48 combinations in total). The results showed variation of frictional torque in different frequencies for all four samples under constant axial load. It was observed that the frictional torque had the lowest value for the implant with ball radius of 16mm. It might be concluded that the implant with larger ball radius may create less friction and hence offer a longer life