The purpose of this study is to quantify the distribution of bone density in the scapulae of patients undergoing reverse shoulder arthroplasty (RSA) to guide optimal screw placement. To achieve this aim, we compared bone density in regions around the glenoid that are targeted for screw placement, as well as bone density variations medial to lateral within the glenoid. Specimen included twelve scapula in 12 patients with a mean age of 74 years (standard deviation = 9.2 years). Each scapula underwent a computed tomography (CT) scan with a Lightspeed+ XCR 16-Slice CT scanner (General Electric, Milwaukee, USA). Three-dimensional (three-D) surface mesh models and masks of the scapulae containing three-D voxel locations along with the relative Hounsfield Units (HU) were created. Regions of interest (ROI) were selected based on their potential glenoid baseplate screw positioning in RSA surgery. These included the base of coracoid inferior and lateral to the suprascapular notch, an anterior and posterior portion of the scapular spine, and an anterosuperior and inferior portion of the lateral border. Five additional regions resembling a clock face, on the glenoid articular surface were then selected to analyze medial to lateral variations in bone density including twelve, three, six, and nine-o'clock positions as well as a central region. Analysis of Variance (ANOVA) tests were used to examine statistical differences in bone density between each region of interest (p < 0 .05). For the regional evaluation, the coracoid lateral to the suprascapular notch was significantly less dense than the inferior portion of the lateral border (mean difference = 85.6 HU, p=0.03), anterosuperior portion of the lateral border (mean difference = 82.7 HU, p=0.04), posterior spine (mean difference = 97.6 HU, p=0.007), and anterior spine (mean difference = 99.3 HU, p=0.006). For the medial to lateral evaluation, preliminary findings indicate a “U” pattern with the densest regions of bone in the glenoid most medially and most laterally with a region of less dense bone in-between. The results from this study utilizing clinical patient CT scans, showed similar results to those found in our previous cadaveric study where the coracoid region was significantly less dense than regions around the lateral scapular border and scapular spine. We also have found for medial to lateral bone density, a “U” distribution with the densest regions of bone most medially and most laterally in the glenoid, with a region of less dense bone between most medial and most lateral. Clinical applications for our results include a carefully planned trajectory when placing screws in the scapula, potentially avoiding the base of coracoid. Additionally, surgeons may choose variable screw lengths depending on the region of bone and its variation of density medial to lateral, and that screws that pass beyond the most lateral (subchondral) bone, will only achieve further purchase if they enter the denser bone more medially. We suspect that if surgeons strategically aim screw placement for the regions of higher bone density, they may be able to decrease micromotion in baseplate fixation and increase the longevity of RSA

Percutaneous cannulated screw placement (PCSP) is a common method of fixation. In pelvic trauma neurovascular structures are in close proximity to the screw path. Pre-operative planning is needed to prevent injury. This study aims to the safety margin and accuracy of screw placement with computer navigation (CAS). A control had no pathology in the pelvis but CT scans were performed for suspected trauma. The treated group had pelvic and acetabular fractures and were treated with CAS PCSP at our institution. Using a new technique involving CT 3D modelling of the whole (3D) safe corridor, the dimensions of the Posterior elements (PE) of the pelvic ring and the anterior column of the acetabulum (AC) were measured in the control group. The accuracy of screw placement (deviation between the actual screw and planned screw) was measured in treated patient using a screenshot method and post-operative CTs. There were 22 control patients and 30 treated patients (40 screws). The mean ± (standard deviation, SD) minimum measurement of the safe corridor at the PE was 15.6 ± 2.3 mm (range 11.6 mm to 20.2 mm) and at the AC was 5.9 ±1.6 mm (range 3.0 mm to 10.0 mm). The mean ± (SD) accuracy of screw placement was 6.1 ± 5.3 mm and ranged from a displacement of 1.3 mm to 16.1 mm. There was a notable correlation between Body Mass Index, duration of surgery and inaccuracy of screw placement in some patients. The largest inaccuracy of screw placement was due to reduction of the fracture during screw insertion, causing movement of the bone fragments relative to the array and therefore also the computerised screw plan. There were no screw breakages, non-unions, neurological or vascular complications. CAS PCSP is a safe and accurate technique. However, the safe corridor is variable and often very narrow. We recommend that the dimensions of the safe corridor be assessed pre-operatively in every patient using 3D modelling to determine the number and size of screw that can be safely placed

The accuracy of pedicle screw placement is essential for successful spinal reconstructive surgery. The authors of several previous studies have described the use of image-based navigational templates for pedicle screw placement. These are designed based on a pre-operative computed tomographic (CT) image that fits into a unique position on an individual's bone, and holes are carefully designed to guide the drill or the pedicle probe through a pre-planned trajectory. The current study was conducted to optimise navigational template design and establish its designing method for safe and accurate pedicle screw placement. Thin-section CT scans were obtained from 10 spine surgery patients including 7 patients with adolescent idiopathic scoliosis (AIS) and three with thoracic ossification of the posterior longitudinal ligament (OPLL). The CT image data were transferred to the commercially available image-processing software and were used to reconstruct a three-dimensional (3D) model of the bony structures and plan pedicle screw placement. These data were transferred to the 3D-CAD software for the design of the template. Care was taken in designing the template so that the best intraoperative handling would be achieved by choosing several round contact surfaces on the visualised posterior vertebral bony structure, such as transverse process, spinous process and lamina. These contact surfaces and holes to guide the drill or the pedicle probe were then connected by a curved pipe. STL format files for the bony models with planned pedicle screw holes and individual templates were prepared for rapid prototype fabrication of the physical models. The bony models were made using gypsum-based 3D printer and individual templates were fabricated by a selective laser melting machine using commercially pure titanium powder. Pedicle screw trajectory of the bony model, adaptation and stability of the template on the bony model, and screw hole orientation of the template were evaluated using physical models. Custom-made titanium templates with adequate adaptation and stability in addition to proper orientation of the screw holes were sterilised by autoclave and evaluated during surgery. During segmentation, reproducibility of transverse and spinous processes were inferior to the lamina and considered inadequate to select as contact surfaces. A template design with more bone contact area might enhance the stability of the template on the bone but it is susceptible to intervening soft tissue and geometric inaccuracy of the template. In the bony model evaluation, the stability and adaptation of the templates were sufficient with few small round contact surfaces on each lamina; thus, a large contact surface was not necessary. In clinical patients, proper fit for positioning the template was easily found manually during the operation and 141/142 screws were inserted accurately with 1 insignificant pedicle wall breach in AIS patient. This study provides a useful design concept for the development and introduction of custom-fit navigational template for placing pedicle screws easily and safely

Introduction: Percutaneous cannulated screw placement (PCSP) is a safe method of internal fixation, indicated for pelvic ring fractures. Due to the close proximity of neurovascular structures to the path of the screw placed in either the Posterior elements (PE) or Anterior column (AC), pre-operative planning is needed to prevent injury. This study aims to develop a pre-operative protocol for the Australian population, regarding the safe number of screws and size of screw that may be placed. Additionally, results from the study may help identify patients at increased risk of injury during PCSP. Methods: All patients were from the Australian population and had been admitted into the emergency department at The Royal Melbourne Hospital. Control patients had no pathology in the pelvis, while treated group patients had pelvic ring fractures and were treated with PCSP. Safe corridor measurements of the PE and AC were taken in the control patients. Pelvic CT scans, taken as part of trauma protocol, were reconstructed using 3D modelling and the dimensions of the whole (3 dimensional) safe corridor measured. The accuracy of screw placement was determined in each treated patient. Accuracy was assessed by the screenshot method, the post-operative CT method or by both methods. In both methods, accuracy was taken as the deviation between the positions of the actual screw and planned screw. Results: There were 22 control patients and 12 treated patients. The mean ± (standard deviation, SD) minimum measurement of the safe corridor at the PE was 15.6 ± 2.3 mm (range 11.6 mm to 20.2 mm) and at the AC was 5.9 ±1.6 mm (range 3.0 mm to 10.0 mm). The mean ± (SD) accuracy of screw placement was 6.1 ± 5.3 mm and ranged from a displacement of 1.3 mm to 16.1 mm. Conclusion: The minimum dimensions of the safe corridor and the accuracy of screw placement occurred over a wide range. We recommend that dimensions of the safe corridor be assessed pre-operatively in every patient using 3D modelling to determine the safe number and size of screw that can be placed

We present an analysis of manual and computer-assisted preoperative pedicle screw placement planning. Preoperative planning of 256 pedicle screws was performed manually twice by two experienced spine surgeons (M1 and M2) and automatically once by a computer-assisted method (C) on three-dimensional computed tomography images of 17 patients with thoracic spinal deformities. Statistical analysis was performed to obtain the intraobserver and interobserver variability for the pedicle screw size (i.e. diameter and length) and insertion trajectory (i.e. pedicle crossing point, sagittal and axial inclination, and normalized screw fastening strength). In our previous study, we showed that the differences among both manual plannings (M1 and M2) and computer-assisted planning (C) are comparable to the differences between manual plannings, except for the pedicle screw inclination in the sagittal plane. In this study, however, we obtained also the intraobserver variability for both manual plannings (M1 and M2), which revealed that larger differences occurred again for the sagittal screw inclination, especially in the case of manual planning M2 with average differences of up to 18.3°. On the other hand, the interobserver variability analysis revealed that the intraobserver variability for each pedicle screw parameter was, in terms of magnitude, comparable to the interobserver variability among both manual and computer-assisted plannings. The results indicate that computer-assisted pedicle screw placement planning is not only more reproducible and faster than, but also as reliable as manual planning

Background. Accurate insertion of pedicle screws in scoliosis patients is a great challenge for surgeons due to the severe deformity of thoracic and lumbar spine. Meanwhile, mal-position of pedicle screw in scoliosis patients could lead to severe complications. Computer-assisted navigation technique may help improving the accuracy of screw placement and reducing complications. Thus, this meta-analysis of the published researches was conducted concentrating on accuracy of pedicle screw placement and postoperative assessment in scoliosis patients using computer-assisted navigation technique. Methods. PubMed, Cochrane and Web of Science databases search was executed. In vivo comparative studies that assessed accuracy and postoperative evaluation of pedicle screw placement in scoliosis patients with or without navigation techniques were involved and analysed. Results. One published randomised controlled trial (RCT) and seven retrospective comparative studies met the inclusion criteria. These studies included 321 patients with 3821 pedicle screws inserted. Accuracy of pedicle screw insertion was significantly increased with using of navigation system, while average surgery time was not significantly different with non-navigated surgery. And Correction rate for scoliosis in navigated surgery was not significantly different with non-navigated surgery. Conclusions. Navigation technique does indeed improve the accuracy of pedicle screw placement in scoliosis surgery, without prolong the surgery time or decrease the deformity correction effect

Pedicle screw fixation is an effective and reliable method for achieving stabilization in lumbar degenerative disease. The procedure carries a risk of violating the spinal and neural canal which can lead to nerve injury. This audit examines the accuracy of screw placement using intra-operative image guidance. Retrospective audit of patients undergoing lumbar pedicle screw fixation using image guidance systems over an 18-month period. Case records were reviewed to identify complications related to screw placement and post-operative CT scans reviewed to study the accuracy of screw position. Of the 98 pedicle screws placed in 25 patients, pedicle violation occurred in 4 screw placements (4.1%). Medial or inferior breach of the pedicle cortex was seen in 2 screws (2%). Nerve root injury as a consequence of this violation was seen in one patient resulting in irreversible partial nerve root dysfunction. Mean set up time for the guidance system was 42 minutes. The mean operative time was 192 minutes. Violation of either the medial or inferior pedicle cortex during placement of fixation screws is a rare, but potentially serious complication bearing lasting consequences. Image-guided placement can be helpful and possibly improve accuracy; particularly in patients with distorted spinal anatomy

Objectives. Percutaneous iliosacral screw placement is a standard, stabilization technique for pelvic fractures. The purpose of this study was to assess the effectiveness of a novel biplanar robot navigation aiming system for percutaneous iliosacral screw placement in a human cadaver model. Methods. A novel biplanar robot navigation aiming system was used in 16 intact human cadaveric pelvises for percutaneous iliosacral screw insertion. The number of successful screw placements and mean time for this insertion and intra-operative fluoroscopy per screw-pair were recorded respectively to evaluate the procedure. The accuracy of the aiming process was evaluated by computed tomography. Results. Sixteen intact human cadaveric pelvises were treated with percutaneous bilateral iliosacral S1 screw placement (32 cannulated screws, diameter-7.3mm, Synthes, Switzerland). All screws were placed under fluoroscopy-guided control using the biplanar robot navigation aiming system (TINAV, GD2000, China). There was no failed targeting for screw-pair placements. Computed tomography revealed high accuracy of the insertion process. 32 iliosacral screws were inserted (mean operation time per screw-pair 56 ± 3 minutes, mean fluoroscopy time per screw-pair 11.7 ± 9 seconds). In post-operative CT-scans the screw position was assessed and graded as follows: I. secure positioning, completely inserted in the cancellous bone (86%); II. secure positioning, but contacting cortical bone structures (9%); III. malplaced positioning, penetrating the cortical bone (5%). Conclusion. This cadaver study indicated that an aiming device–based biplanar robot navigation system is highly reliable and accurate. The promising results suggest that it has the advantages of high positioning accuracy, decreased radiation exposure, operational stability and safety. It can be used not only for the percutaneous iliosacral screw placement but also for other orthopedic surgeries that require precise positioning

Introduction: For plate osteosynthesis (OS) many surgeons use a rigid fixation which prevents callus formation. The present paper applies biomechanical laws and a FE analysis for optimal screw placement to turn a rigid plate OS into a dynamic and biological OS. Methods: A Finite Element Analysis was performed. The bone was modeled as a cylinder with an outer diameter of 30 mm and an inner diameter of 22 mm. An E-modul of 18 GPa was assumed for cortical bone. A DC steel plate was modeled with a preload of 300 N for each screw. Fracture motion and stress on the screw head was calculated for different screw placements and a load of 300 N angulated at 30 deg. Results: The number of screws did not influence fracture motion. This could only be controlled by the distance of the first screw to the fracture site, the use of a lag screw and the material of the plate. When one screw hole was omitted close to the fracture site, motion doubled. Using A lag screw reduced fracture motion dramatically. The stress was greatest at the screw closest to the fracture site. Conclusions: In order to achieve a dynamic plate OS with callus formation a long plate with a minimal amount of screws and no lag screws should be used. To adjust the flexibility of the OS, the distance of the first screw to the fracture site is the most crucial parameter. Additional screws do not influence the stiffness. The stress is highest at the screw head close to the fracture site. This screw is endangered for fatigue failure. To reduce the stress on this screw it must not be placed oblique and also not eccentric. However, the last screw has little stress and should be placed oblique to increase the pull out strength

Pedicle screws allow for biomechanically secure fixation of the spine. However if they are misplaced they may effect the strength of the fixation, damage nerve roots or compromise the spinal cord. For these reasons image guidance systems have been developed to help with the accuracy of screw placement. The accuracy of pedicle screw placement outside the lumbar spine is not well published. To determine the accuracy of pedicle screw placement using CT scanning post operatively. Cortex perforations were graded in 2mm steps. Prospective observational study. Plain x-rays are inaccurate for determining screw placement and therefore high definition CT scanning was used. The screw positioning on the post-operative CT scans was independently determined by a research registrar who was not present at the time of surgery. Screw position and clinical sequelae of any malposition. Thirty patients (13 F:17 M) with segmental instability. Twelve were for metastatic disease, seven for trauma, seven for spondylolisthesis, three for atlanto-axial instability and one for a vertebral haemangioma. All patients were operated on by the senior author. One hundred and seventy six pedicle screws were inserted in the thirty patients over the 20 month study period. Six screws violated the lateral cortex of the pedicle but none perforated the medial cortex. There were no adverse neurological sequelae. The findings from this study will serve as a good comparison with future studies on pedicle screw placement, which may claim to improve accuracy and safety by the use of image guidance systems, electrical impedance or malleable endoscopes

Aim: To test the null hypothesis that plain X-rays can provide the same assessment of sacral screw placement as CT. Introduction: Engaging the anterior cortex of the sacrum provides additional strength to fixation and is a goal of surgery. The sacrum with its unique anatomy makes it a difficult bone to assess screw placement radiologically. This study examines the positioning of sacral screws as seen on X-rays and compares the result with spiral CT “gold standard”. Materials and methods: Inclusion criteria: Sacral fixation using Diapason (Stryker) Titanium pedicle screws by one surgeon. Spiral CT, plain AP and lateral X-rays of the sacrum. Exclusion criteria: X-rays with more than three level fixation. There were 66 patients (132 S1 screws). Surgical technique engaged the anterior cortex to enhance fixation. Two independent observers (a musculoskeletal radiologist and spinal fellow) who were blinded to outcome, reported findings in forms with constrained fields. Assessment of plain X-ray and CT was at separate times not less than three weeks apart. Variables noted: Screw position in pedicle, screw tip position, and angle of screw (sagittal on axial CT scans). AP X-ray was divided, for each screw, into nine zones based on the first sacral foramina. The position of the screw tip in the zones was noted. The lateral X-ray was divided into three zones to note the tip of the screw in relation to the cortex. The extent of screw protrusion was measured. X-ray technique: Supine AP centred on fusion and lateral X-ray standing, X-ray source 200 cm from the film. CT: Images acquired on Picker PQ 6000 spiral CT with collimated thickness of 3 mm, pitch 1.25 and reconstructive index of 1.Para-sagittal and coronal reconstructions. Spiral CT was used to note the position of the screw within the pedicle and the relation of the screw tip to the anterior cortex. For screws within the pelvis any structure in close proximity was noted. Results: On CT 10% of the screws had breached the pedicle compared with 2% on the plain X-rays. Anterior cortical perforation had been achieved in 48 out of 132 screws on CT. The sensitivity of the plain X-rays to perforation was 40% with a specificity of 92%. There was an average under estimation of the extent of screw perforation by 4.4 mm (95% confidence ±1 mm). There was a correlation between the position of the screw tip on the AP X-ray and the sensitivity of the lateral X-ray to detect a perforation. The sensitivity ranged from 52% for zone 1 to 15% in zone 8. 15/31 perforations were missed in zone 1, compared with 11/13 in zone 8. For screws penetrating 5 mm or more, in zone 8, 9 out of 10 were missed on lateral X-rays. Eighty-five screws were placed at an angle of less than or equal to 25° to the sagittal; this included 28 out of 34 screws placed in zone 8. The inter-observer variance of screw angle measurement was 1.1° and intra-observer difference 1.7°. Overall 95% confidence of a single measurement was ±3.3°. Conclusion: Plain X-rays and CT do not provide the same assessment of sacral screw placement. This is particularly true for sagitally placed screws with screw tips in zones 7–8

INTRODUCTION. Isolated injuries of the sacral bone are rare. The pathomechanism of these injuries are usually high velocity accidents or falls from large heights. The computer-assisted implantation of iliosacral screws (SI-screw) becomes more important in the treatment of dorsal pelvic ring fractures. The advantage of the minimal-invasive screw placement is the reduction of the non-union and deep wound infection rate. Another advantage of computer-navigated SI-screw placement is the reduction of intraoperative radiation for the patient and the surgical staff. The purpose of this study was to analyse the position of navigated iliosacral screws. METHODS. In the study group 74 screws (49 patients) were included and radiologically analysed. All screws were implanted using 3D-navigation (BrainLAB Vector Vision, Brainlab, Germany). Navigation was always executed with the same 3D c-arm (ARCADIS Orbic 3D, Siemens, Germany) and navigation system. We determined the grade of perforation and angular deviation in the postoperative CT-scans in all screws. The classification was performed according to Smith et al in 4 grades. Grade 0 implies no perforation and grade 1 a perforation less than 2 mm. Grade 2 correlates a perforation of 2–4 mm and grade 3 a perforation of more than 4 mm. Furthermore the intra- and postoperative complications as well as the body-mass-index, the co-morbidities and the duration of radiation were documented. The statistical analysis was executed using Microsoft Excel 2003. RESULTS. The mean age of the 49 patients was 42.2 years ± 18 (16–79 years). 28 male and 21 female patients were included. 25 patients received a single iliosacral screw in S1. In 19 cases a screw in S1 and S2 was placed on the same side. Four patients got bilateral SI-screws in S1 and another patient received bilateral screw placement in S1 as well as an additional screw in S2. The mean operation time was 100 min ±103 (20–540 min). The isolated time for SI-placement was 50 min ± 20 (20–93 min). The mean radiation time was 3 min ± 1.7 (0.9–7.4 min) (n = 28). Altogether 84% of the screws showed an intraosseous position (grade 0). In the axial plane 7 screws perforated ventrally, 5 screws penetrated the adjacent neural foramen. In the frontal plane the screws showed greater variations, 61% deviated less than 5° (grade 0). In the study group 5 screws needed surgical revision because of either malplacement or postoperative pain. There were no infections or neurological complications. There was no statistical correlation between screw perforation and the body-mass-index. CONCLUSION. The computer-assisted implantation of iliosacral screws is a safe method in relation to screw perforation. It shows a high security and accuracy concerning the ventral and dorsal cortical perforation. There is a frequent angular deviation in the frontal view without appearance of screw perforation or mechanic, neurologic and angiologic complications. The minimal-invasive procedure shows a low postoperative revision rate

Background: Misplaced pedicle screws are associated with significant complications during posterior spinal instrumentation. Purpose: The purpose of this study is to evaluate the efficacy of triggered electromyographic stimulation in predicting the appropriate placement of pedicle screws. Study Design: Prospective clinical trial. Patient Sample: Fifteen consecutive patients (3 males; 12 females). Outcome Measures: Not applicable. Materials and Methods: All patients underwent posterior thoracolumbar spine fusion. Surgery was performed for spondylolisthesis, spinal stenosis, degenerative scoliosis and fractures. All patients received continuous electromyographic monitoring during surgery. During insertion of pedicle screws the integrity of the medial pedicle cortex was tested by stimulating each screw head with a monopolar pedicle probe stimulator and recording the compound muscle action potentials. A threshold of 7 mA and below was considered indicative of pedicle breach. Intraoperative screw placement was verified with the use of image intensifier. Finally, all patients following surgery underwent plain radiographs and CT scan of the operated region to evaluate the position of the pedicle screws. Results: One hundred and fourteen pedicle screws were inserted from T7 to S1 in all patients. There were no myogenic responses at the threshold tested. No screw had to be repositioned intraoperatively. There were no new neurologic deficits recorded following surgery. Review of the radiographs and CT scans obtained following surgery revealed no medial pedicle cortex breach. There were two screws that violated the lateral pedicle cortex, without any subsequent complications for the patients. Conclusions: Our study suggests that the absence of myogenic responses following stimulation at a threshold of 7 mA and below during pedicle screw placement, is a strong indicator that no medial pedicle cortex breach has occurred

Purpose of study:. Reverse shoulder arthroplasty is effective in the management of symptomatic arthritic shoulders with a non-reconstructable rotator cuff. Optimal orientation and initial fixation of the glenoid component is correlated with improved outcomes. This may be difficult to achieve with distorted glenoid morphology. The authors present a previously undescribed system for accurate, consistent and reliable screw placement for fixation of the glenoid component with the desired version during reverse shoulder arthroplasty. Description of methods:. The pre-operative CT scan images are used to construct a scapula model (Medical Image Processing software, CustomMed Orthopaedics)allowing the surgeon to determine the optimal position for screw placement based on available bone stock. A custom drill guide is made from polyamide, which is sterilized in an autoclave and fitted to the glenoid intra-operatively prior to reaming. The system minimizes the likelihood of malposition of glenoid components and is compatible with all arthroplasty systems. Summary of results:. The technique has been performed on 5 patients after informed consent. Post-operative CT images demonstrate intended component version and screw position in all cases. Patients are being recruited for a multicenter prospective trial. Conclusion:. The authors present a new technique for achieving optimal screw position in fixation of glenoid components. A prospective trial is underway which aims to prove through post-operative imaging that intended glenoid version and screw placement was achieved and show improved long term results

Percutaneous placement of pedicle screws is a well-established technique, however, no studies have compared percutaneous and open placement of screws in the thoracic spine. The aim of this cadaveric study was to compare the accuracy and safety of these techniques at the thoracic spinal level. A total of 288 screws were inserted in 16 (eight cadavers, 144 screws in percutaneous and eight cadavers, 144 screws in open). Pedicle perforations and fractures were documented subsequent to wide laminectomy followed by skeletalisation of the vertebrae. The perforations were classified as grade 0: no perforation, grade 1: < 2 mm perforation, grade 2: 2 mm to 4 mm perforation and grade 3: > 4 mm perforation. In the percutaneous group, the perforation rate was 11.1% with 15 (10.4%) grade 1 and one (0.7%) grade 2 perforations. In the open group, the perforation rate was 8.3% (12 screws) and all were grade 1. This difference was not significant (p = 0.45). There were 19 (13.2%) pedicle fractures in the percutaneous group and 21 (14.6%) in the open group (p = 0.73). In summary, the safety of percutaneous fluoroscopy-guided pedicle screw placement in the thoracic spine between T4 and T12 is similar to that of the conventional open technique. Cite this article: Bone Joint J 2015;97-B:1555–61

To evaluate the clinical accuracy of computer-assisted fluoroscopy for the placement of percutaneous lumbosacral (LS) pedicle screws. A prospective computed tomographic (CT) analysis was performed in forty consecutive patients. Three independent observers were utilised. Postoperative CT scans of one hundred and fifty-nine titanium pedicle screws (n = 6(L3); thirty-eight(L4); sixty-five(l5) and fifty(S1)) were reviewed. All screws were percutaneously placed using the two-dimensional FluoroNavTM system. The relative position of the screw to the pedicle was graded as follows: I-completely in; II – < 2mm breach; III - = 2–4mm breach; IV – > 4mm breach. The direction of the breach was further classified as well as its trajectory. Correlation between observers was near perfect. The three observers rated 74.2%, 78.6%, and 78.0% of screws were completely contained within the pedicle. The data from the observer with the most significant pedicle breaches is as follows: thirty-five (22%) pedicle breaches (grade II -n=30; III - n=4; IV - n=1/n= 11 medial; n=19 lateral; 5 superior). Only one clinically significant breach occurred medially (grade III) at L5. This required screw revision (performed with a minimal access technique) with complete resolution of acute post-op L5 radiculopathy. The in-vivo percutaneous pedicle breach rate in this study was higher than that reported for similar open navigational techniques. The majority (85.7%) of breaches were minor (< 2mm) and over half (54.3%) were lateral with no potential for clinical squealae. This high lateral breach rate is due to a modified lateral starting point required for the percutaneous technique. However, there is concern that this technique resulted in one clinically significant medial breach and highlights the increased risk associated with percutatneous pedicle screw placement. The findings of this study suggest that improved screw placement accuracy for minimal access instrumented fusions is required

Introduction. Pedicle screw fixation is considered gold standard as it provides stable and adequate fixation of all the three columns of spine. Mal-placement of screws in dorso-lumbar region, using fluoroscopic control only, varies from 15% to 30 %. The aim of this study was to determine whether accuracy of pedicle screw placement can be improved using CT based navigation technique. Material & methods. 15 patients with fracture of D12 in 4 patients, L1 in 6 patients, L2 in 4 patients, and L4 in 1 patient underwent pedicle screw fixation using CT based navigation. Each fracture was fixed with 4 pedicle screws, 2 each in one level above and one level below the fractured vertebrae. A total of 60 pedicle screws was inserted. A pre-operative 1mm slice planning CT scan was taken from two levels above to two levels below the fractured vertebrae. It was loaded into the workstation and pre-operative planning was made of screw trajectory and screw size i.e. thickness and length, according to the dimensions of the pedicle and vertebral body. Screws were then inserted using opto-electronic navigation system. Screw placement was analysed in all patients using post-operative CT scan and graded according to the Laine's system. Results. The average time for matching was 10.8 minutes and average time for screw insertion was 4.3 minutes (range 2-8 minutes). One screw in right sided pedicle of L2 perforated the lateral cortex (1.66%). There was no neuro-vascular complication. Conclusion. The incidence of a misplaced screw in the present study is only 1.66% which is much less than reported with conventional technique, reflecting enhanced accuracy with computer assisted navigation. Thus computer assisted navigation is a potent tool in the hands of a spine surgeon in improving the accuracy of pedicle screw placement

Using finely reconstructed helical pelvis CT scans of ninety-three cases and image analysis software, we define the “Safe Zone” for the extra-articular placement of screws during internal fixation of the acetabulum, using a Stoppa approach. Screws should be at most: 11mm from the top of the Sciatic notch, 23mm from the tip of the Ischial Spine, and at most 5mm posterior to the top of the Obturator canal, along the pelvic brim. The purpose of this study was to identify a “safe zone” in the inner pelvis, to allow extra-articular screw placement using the Stoppa approach. Acetabulum internal fixation screws can safely (extra-articular position) be placed through the Stoppa approach using three identifiable landmarks. Surgeons can use these identifiable anatomic landmarks for the safe placement of screws along the inner aspect of the acetabulum. Study Population: males:females 47%:53%, mean age: 51,3yrs (18–88). Reference measurements (means): Femoral Head (FH): 45,5mm (36–6), Inter-SI joint:177,9mm (102–34). Safe distance to joint: 1) from Sciatic notch: 11mm; 2) from Ischial Spine: 23mm; 3) from Obturator roof: 5mm. The Ischial Spine Distance (ISD) showed clustering (p< 0.05) into two groups according to Femoral Head diameter: FH< 47mm: Safe ISD=23mm ; FH≥47mm: Safe IS=28mm. Ninety-three Helical Pelvis CT scans with fine reconstruction were done between July 1, 1999-June 30, 2000. Axial images were analyzed using GE Vox Tool® v.3.0.3 image analysis software. The femoral head diameter and the Inter-SI joint distance were used as reference. The distance between three identifiable bony landmarks and the point which would allow the placement of a 4mm screw outside the hip joint were measured. Inter and Intra-observer reliability study showed a difference < 1mm in > 90% of cases. Surgical approaches which avoid extensive dissection and manipulation of the gluteal musculature are gaining in popularity. The Stoppa is such an approach which gives access to the medial acetabular wall and to the inner pelvis from the SI joint to the symphysis along the pelvic brim. This blind approach does not allow visualisation of the joint and confirmation of screw placement. The present paper offers surgeons these reference points

The use of cervical pedicle screws as anchors in posterior reconstruction surgery has not been widely accepted due to the neurological or vascular injury. We thus sought to investigate the accuracy of free-handed pedicle screw placement in the cervical and upper thoracic spine at the early stage of clinical application. Eight patients (five males and three females) were included in this study. Mean age was 63 years (31 to 78 years). There were three patients with rheumatoid arthritis, three with cervical fracture-dislocation, and two with spinal metastasis. Twenty-four pedicle screws (3.5 mm diameter: Vertex, Medtronic Sofamordanek) were placed into the pedicle from C2 to T2 level by free-handed technique2). Grade of breaching of pedicle cortex was divided into four groups (Grade 0–3). In addition, screw axis angle (SAA) were calculated from the horizontal and sagittal CT images and compared with pedicle transverse angle (PTA). Furthermore, perioperative complications were also examined. Our free-handed pedicle screw placement with carving technique is as follows: A longitudinal gutter was created at the lamina-lateral mass junction and then transverse gutter perpendicular to the longitudinal gutter was made at the lateral notch of lateral mass. The entry point of the pedicle screw was on the midline of lateral mass. Medial pedicle cortex through the ventral lamina was identified using the probes to create the hole within the pedicle. The hole was tapped and the screw was gently introduced into the pedicle to ensure the sagittal trajectory using fluoroscopy. In the transverse direction, 22 out of 24 screws (92%) were entirely contained within the pedicle (Grade 0). In contrast, only teo screws (8%) produced breaches less than half the screw diameter (Grade 1). In the sagittal direction, all screws were within the pedicle (Grade 0). Screw trajectories were not consistent with anatomical pedicle axis angle; the mean SAA were smaller than the mean PTA at all levels. The pedicle diameter ranged from 3.9 to 9.2 mm. The mean value gradually increased toward the caudal level. There were no neurological and vascular complications related to screw placement

Using post-operative CT analysis the clinical accuracy of computer-assisted fluoroscopy for the placement of thoracic (n=69) and lumbosacral (n=271) pedicle screws was assessed. All screws were placed using the Fluoro-Nav™ system (Medtronic Sofamor Danek, Memphis, TN, USA). Screw position was completely intrapedicular in 86.5%. There were no clinically significant screw misplacements. Pedicle breaches with a potential for neurological injury (> 2 mm; medial) was 0.6%. The overall pedicle screw misplacement rate in this study is less than or comparable to reported misplacement rates using other techniques. The use of computer-assisted fluoroscopy may improve the safety of pedicle screw placement. The purpose of this prospective study is to evaluate the clinical accuracy of computer-assisted fluoroscopy for the placement of thoracic (T) and lumbosacral (LS) pedicle screws. The overall thoracic and lumbar pedicle screw misplacement rate in this study is less than or comparable to reported misplacement rates using other techniques. The use of computer-assisted fluoroscopy may improve the safety of pedicle screw placement. Postoperative computed tomographs (CT) of three hundred and forty pedicle screws were independently reviewed. All screws were placed using the Fluoro-Nav™ system (Medtronic Sofamor Danek, Memphis, TN, USA). The relative position of the screw to the pedicle was assessed and graded as follows – A- completely in; B – < 2mm breach; C – 2–4mm breach; D – > 4–6mm breach. If an osseous breach occurred, the direction of the breach was further classified. Overall screw position was graded A in 86.5% (294/340) of screws (91.1 % (24/271) -lumbosacral and 68.1.0% (47/69)-thoracic). Forty-six pedicle breaches occurred (24 medial; 22 lateral). Thirty-five percent (16/46) of breaches were unavoidable secondary to a pedicle screw that was larger than the size of pedicle (thoracic-13). Pedicle breaches were Grade B in 11.8%, Grade C in 1.5% and Grade D in 0.3% of screws. There were no clinically significant screw misplacements. Pedicle breaches with a potential for neurological (> 2 mm; medial) or vascular injury was 0.6% and 0% respectively. FluoroNav™ appears to be a safe and practical adjunct for the placement of thoracic and lumbosacral pedicle screws. Funding: Medtronic-Sofamor Danek – research support