Aims. A local injection may be used as an early option in the treatment of Morton’s neuroma, and can be performed using various medications. The aim of this study was to compare the effects of injections of hyaluronic acid compared with corticosteroid in the treatment of this condition. Methods. A total of 91 patients were assessed for this trial, of whom 45 were subsequently included and randomized into two groups. One patient was lost to follow-up, leaving 22 patients (24 feet) in each group. The patients in the hyaluronic acid group were treated with three ultrasound-guided injections (one per week) of hyaluronic acid (Osteonil Plus). Those in the corticosteroid group were treated with three ultrasound-guided injections (also one per week) of triamcinolone (Triancil). The patients were evaluated before treatment and at one, three, six, and 12 months after treatment. The primary outcome measure was the visual analogue scale for pain (VAS). Secondary outcome measures included the American Orthopaedic Foot and Ankle Society (AOFAS) score, and complications. Results. Both groups showed significant improvement in VAS and AOFAS scores (p < 0.05) after 12 months. The corticosteroid group had a significantly greater reduction in VAS and increase in AOFAS scores compared with the hyaluronic acid group, at one, three, and six months, but with no significant difference at 12 months. There were no complications in the hyaluronic acid group. There were minor local complications in six patients (six feet) (25.0%) in the corticosteroid group, all with discolouration of the skin at the site of the injection. These minor complications might have been due to the three weekly injections of a relatively high dose of corticosteroid. No patient subsequently underwent excision of the neuroma. Conclusion. An ultrasound-guided corticosteroid injection showed statistically significantly better functional and
To describe outcome reporting variation and trends in non-pharmacological randomized clinical trials (RCTs) of distal tibia and/or ankle fractures. Five electronic databases and three clinical trial registries were searched (January 2000 to February 2022). Trials including patients with distal tibia and/or ankle fractures without concomitant injuries were included. One reviewer conducted all searches, screened titles and abstracts, assessed eligibility, and completed data extraction; a random 10% subset were independently assessed and extracted by a second reviewer at each stage. All extracted outcomes were mapped to a modified version of the International Classification of Functioning, Disability and Health framework. The quality of outcome reporting (reproducibility) was assessed.Aims
Methods
In this retrospective cohort study, we analysed
the incidence and functional outcome of a distal tibiofibular synostosis.
Patients with an isolated AO type 44-B or C fracture of the ankle
who underwent surgical treatment between 1995 and 2007 were invited
for clinical and radiological review. The American Orthopaedic Foot
and Ankle Society score, the American Academy of Orthopaedic Surgeons
score and a visual analogue score for pain were used to assess outcome. A total of 274 patients were available; the mean follow-up was
9.7 years (8 to 18). The extent of any calcification or synostosis
at the level of the distal interosseous membrane or syndesmosis
on the contemporary radiographs was defined as: no or minor calcifications
(group 1), severe calcification (group 2), or complete synostosis
(group 3). A total of 222 (81%) patients were in group 1, 37 (14%) in group
2 and 15 (5%) in group 3. There was no significant difference in
incidence between AO type 44-B and type 44-C fractures (p = 0.89).
Severe calcification or synostosis occurred in 21 patients (19%)
in whom a syndesmotic screw was used and in 31 (19%) in whom a syndesmotic screw
was not used.(p = 0.70). No significant differences were found between
the groups except for a greater reduction in mean dorsiflexion in
group 2 (p = 0.004). This is the largest study on distal tibiofibular synostosis,
and we found that a synostosis is a frequent complication of surgery
for a fracture of the ankle. Although it theoretically impairs the
range of movement of the ankle, it did not affect the outcome. Our findings suggest that synostosis of the distal tibiofibular
syndesmosis in general does not warrant treatment. Cite this article:
