Background. Frozen Shoulder is a common condition which causes significant morbidity in people of working age. The 2 most popular forms of surgical treatment for this condition are Manipulation under Anaesthesia (MUA) or MUA plus Arthroscopic Capsular Release (ACR). Both treatment modalities are known to give good results, but no-one has compared the two to see which is better. Aim. To compare the outcome in patients with primary frozen shoulder, who are treated by either MUA or MUA plus ACR. Methods. 56 patients with primary frozen shoulder were treated by either MUA or MUA plus ACR. Each patient had their American Shoulder and Elbow Score (ASES), and their Oxford Shoulder Score (OSS) measured pre- and post-operatively. Results. The patients who had MUA plus ACR had a mean ASES of 19.6 pre-operatively, 78.3 at 6 months, and a mean of 80.1 at 12 months. The mean OSS was 32.5 pre-operatively, 53.6 at 6 months and 53.8 at 12 months. The patients who had a MUA had a mean ASES of 28.7 pre-operatively, 57.9 at 6 months and 58 at 12 months. The mean OSS was 33 pre-operatively, 42.5 at 6 months and 48 at 12 months. Conclusions. Both treatments give good results; MUA plus ACR give significantly superior results at 6 to 12 months post-operatively. However, there is no significant difference beyond 12 months

Background – Frozen Shoulder is a common condition which causes significant morbidity in people of working age. The 2 most popular forms of surgical treatment for this condition are Manipulation under Anaesthesia (MUA) or MUA plus Arthroscopic Capsular Release (ACR). Both treatment modalities are known to give good results, but no-one has compared the 2 to see which is better. Aim – To compare the outcome in patients with primary frozen shoulder, who are treated by either MUA or MUA plus ACR. Method – 61 patients with primary frozen shoulder were treated by either MUA or MUA plus ACR. Each patient had their American Shoulder and Elbow Score (ASES), and their Oxford Shoulder Score (OSS) measured pre and post-operatively. Results – The patients who had MUA plus ACR had a mean ASES of 24.8 preoperatively, 64 at 4 months, and a mean of 75.4 at 12 months. The mean OSS was 32.5 pre-operatively, 48.5 at 4 months and 53.4 at 12months. The patients who had a MUA had a mean ASES of 28.7 pre-operatively, 60.9 at 4months and 69.6 at 12months. The mean OSS was 33 preoperatively, 46.5 at 4 months and 50.9 at 12 months. Conclusions – Both treatments give good results. MUA plus ACR give superior numerical results at 6 to 12 months post-operatively, however, these figures did not reach statistical significance

Aims. The management of completely displaced fractures of the distal radius in children remains controversial. This study evaluates the outcomes of surgical and non-surgical management of ‘off-ended’ fractures in children with at least two years of potential growth remaining. Methods. A total of 34 boys and 22 girls aged 0 to ten years with a closed, completely displaced metaphyseal distal radial fracture presented between 1 November 2015 and 1 January 2020. After 2018, children aged ten or under were offered treatment in a straight plaster or manipulation under anaesthesia with Kirschner (K-)wire stabilization. Case notes and radiographs were reviewed to evaluate outcomes. In all, 16 underwent treatment in a straight cast and 40 had manipulation under anaesthesia, including 37 stabilized with K-wires. Results. Of the children treated in a straight cast, all were discharged with good range of mo (ROM). Five children were discharged at six to 12 weeks with no functional limitations at six-month follow-up. A total of 11 children were discharged between 12 and 50 weeks with a normal ROM and radiological evidence of remodelling. One child had a subsequent diaphyseal fracture proximal to the original injury four years after the initial fracture. Re-displacement with angulation greater than 10° occurred for 17 children who had manipulation under anaesthesia. Four had a visible cosmetic deformity at discharge and nine had restriction of movement, with four requiring physiotherapy. One child developed over- granulation at the pin site and one wire became buried, resulting in a difficult retrieval in clinic. No children had pin site infections. Conclusion. Nonoperative management of completely displaced distal radial fractures in appropriately selected cases results in excellent outcomes without exposing the child to the risks of surgery. This study suggests that nonoperative management of these injuries is a viable and potentially underused strategy. Cite this article: Bone Joint J 2021;103-B(5):902–907

Aims. Manipulation under anaesthesia (MUA) remains an effective intervention to address restricted range of motion (ROM) after total knee arthroplasty (TKA) and occurs in 2% to 3% of primary TKAs at our institution. Since there are few data on the outcomes of MUA with different anaesthetic methods, we sought to compare the outcomes of patients undergoing MUA with intravenous (IV) sedation and neuraxial anaesthesia. Methods. We identified 548 MUAs after primary TKA (136 IV sedation, 412 neuraxial anaesthesia plus IV sedation) from March 2016 to July 2019. The mean age of this cohort was 62 years (35 to 88) with a mean body mass index of 31 kg/m. 2. (18 to 49). The mean time from primary TKA to MUA was 10.2 weeks (6.2 to 24.3). Pre-MUA ROM was similar between groups; overall mean pre-MUA extension was 4.2° (p = 0.452) and mean pre-MUA flexion was 77° (p = 0.372). We compared orthopaedic complications, visual analogue scale (VAS) pain scores, length of stay (LOS), and immediate and three-month follow-up knee ROM between these groups. Results. Following MUA, patients with IV sedation had higher mean VAS pain scores of 5.2 (SD 1.8) compared to 4.1 (SD = 1.5) in the neuraxial group (p < 0.001). The mean LOS was shorter in patients that received IV sedation (9.5 hours (4 to 31)) compared to neuraxial anaesthesia (11.9 hours (4 to 51)) (p = 0.009), but an unexpected overnight stay was similar in each group (8.6%). Immediate-post MUA ROM was 1° to 121° in the IV sedation group and 0.9° to 123° in the neuraxial group (p = 0.313). Three-month follow-up ROM was 2° to 108° in the IV sedation group and 1.9° to 110° in the neuraxial anaesthesia group (p = 0.325) with a mean loss of 13° (ranging from 5° gain to 60° loss), in both groups by three months. No patients in either group sustained a complication. Conclusion. IV sedation alone and neuraxial anaesthesia are both effective anaesthetic methods for MUA after primary TKA. Surgeons and anaesthetists should offer these anaesthetic techniques to match patient-specific needs as the orthopaedic outcomes are similar. Also, patients should be counselled that ROM following MUA may decrease over time. Cite this article: Bone Joint J 2021;103-B(6 Supple A):126–130

Aims. Postoperative range of movement (ROM) is an important measure of successful and satisfying total knee arthroplasty (TKA). Reduced postoperative ROM may be evident in up to 20% of all TKAs and negatively affects satisfaction. To improve ROM, manipulation under anaesthesia (MUA) may be performed. Historically, a limited ROM preoperatively was used as the key harbinger of the postoperative ROM. However, comorbidities may also be useful in predicting postoperative stiffness. The goal was to assess preoperative comorbidities in patients undergoing TKA relative to incidence of postoperative MUA. The hope is to forecast those who may be at increased risk and determine if MUA is an effective form of treatment. Methods. Prospectively collected data of TKAs performed at our institution’s two hospitals from August 2014 to August 2018 were evaluated for incidence of MUA. Comorbid conditions, risk factors, implant component design and fixation method (cemented vs cementless), and discharge disposition were analyzed. Overall, 3,556 TKAs met the inclusion criteria. Of those, 164 underwent MUA. Results. Patients with increased age and body mass index (BMI) had decreased likelihood of MUA. For every one-year increase in age, the likelihood of MUA decreased by 4%. Similarly, for every one-unit increase in BMI the likelihood of MUA decreased by 6%. There were no differences in incidence of MUA between component type/design or fixation method. Current or former smokers were more likely to have no MUA. Surprisingly, patients discharged to home health service or skilled nursing facility were approximately 40% and 70% less likely than those discharged home with outpatient therapy to be in the MUA group. MUA was effective, with a mean increased ROM of 32.81° (SD 19.85°; -15° to 90°). Conclusion. Younger, thinner patients had highest incidence of MUA. Effect of discharge disposition on rate of MUA was an important finding and may influence surgeons’ decisions. Interestingly, use of cement and component design (constraint) did not impact incidence of MUA. Level of Evidence II: Prospective cohort study. Cite this article: Bone Joint J 2020;102-B(6 Supple A):66–72

Background Adhesive capsulitis of the shoulder is a painful condition that results in gradual loss of joint movement. Numerous treatment modalities have been utilised with variable benefits. Because of the risk of brachial plexus injury and fracture, manipulation under anaesthesia is considered with caution. Aim To determine the rate of manipulation under anaesthesia (MUA) following primary distension arthrogram for adhesive capsulitis of the shoulder. Patients and Methods The case notes of 40 patients (42 shoulders) between 1998 to 2004 at Glenfield Hospital, Leicester under the care of one consultant with adhesive capsulitis of the shoulder treated with distension arthrogram by using intra-articular injection of local anaesthetic, corticosteroid, contrast media and air were reviewed. Results Capsular disruption into the subscapular bursa was demonstrated in all cases. 15 of 42 (36%) shoulders underwent MUA following distension arthrogram. The average period of pain prior to distension arthrogram for these patients was 42 weeks (range: 7–156). 35 of 40 (88%) patients were pain free following primary distension arthrogram. One patient experienced a vasovagal episode during the distension arthrogram. Conclusion Distension arthrogram can be used as a therapeutic procedure for achieving symptomatic pain relief in the early phase of adhesive capsulitis and decreasing the risk of MUA of the shoulder

The optimal timing of when to perform manipulation under anesthesia (MUA) for stiffness following total knee arthroplasty (TKA) is unclear. This study aimed to identify the risk factors for MUA following primary TKA and whether performing an “early” MUA within 3 months results in a greater improvement in range of motion. Primary TKAs performed between January 2013 and December 2018 at three tertiary New Zealand hospitals were reviewed. International Classification of Diseases discharge coding was used to identify patients who underwent an MUA. Multivariate Cox regression was performed to identify patient and surgical risk factors for MUA. Pre- and post-MUA knee flexion angles were identified through manual review of operation notes. Multivariate linear regression was performed to compare the mean flexion angles pre- and post-MUA, as well as the mean gain in flexion, between patients undergoing “early” (<3 months) versus “late” MUA (>3 months). 7386 primary TKAs were analyzed in which 131 underwent subsequent MUA (1.8%). Patients aged <65 years were two times more likely to undergo MUA compared to patients aged ≥65 years (2.5% versus 1.3%, adjusted hazard ratio = 2.1, p<0.001). Gender, body mass index, patient comorbidities or a history of cancer were not associated with the risk of MUA. There was no difference in the final post-MUA flexion angle between patients who underwent early versus late MUA (104.7 versus 104.1 degrees, p = 0.819). However, patients who underwent early MUA had poorer pre-MUA flexion (72.3 versus 79.6 degrees, p = 0.012), and subsequently had a greater overall gain in flexion compared to patients who underwent late MUA (mean gain 33.1 versus 24.3 degrees, p<0.001). Younger age was the only patient risk factor for MUA. A greater overall gain in flexion was achieved in patients who underwent early MUA within 3 months

Introduction. Manipulation under anesthesia (MUA) after total knee arthroplasty (TKA) helps restore range of motion. This study identifies MUA risk factors to support early interventions to improve functionality. Methods. Data was retrospectively reviewed in 2,925 primary TKAs from October 2013 through December 2015 from 13 orthopedic surgeons using hospital and private practice electronic medical records (EMR). Statistical analysis evaluated MUA and non-MUA groups, comparing demographic, operative, hospital-visit, and clinical factors. T-test, chi-square test, ANOVA and regression analysis were performed. Significance was set at p<0.05. Results. Of 2,925 TKAs, 208 MUAs were performed (7.1%) with no significant differences between groups in sex, BMI, or diabetes status. Mean age of the MUA group was 61.98 years old, and 66.89 years old in the non-MUA group (p<0.005). The ratio of MUA patients with high cholesterol was 3.37% (7/208), and 1.10% (30/2717) in the non-MUA group (p=0.014). The ratio of African-American patients in the MUA group was 6.73% (14/208), and 2.94% (80/2717) in the non- MUA group (p=0.003). Of cases with device data recorded in the EMR (n=1890), MUA incidence in patients receiving a cruciate-retaining (CR) device was 14.58% (50/343), and 9.57% (148/1547) in patients receiving a posterior-stabilized (PS) device (p=0.006). A CR-device patient was 52.35% more likely to undergo MUA than a PS-device patient (95% CI, 1.13–2.05). MUA rate by surgeon training was 6.7% for joint fellowship, 6.8% for general fellowship, and 12.0% for sports medicine fellowship (p=0.015). Further analysis showed that rate of CR-device use was 13.3% for joint-fellowship trained surgeons, 10.2% for general fellowship, and 74.7% for sports medicine fellowship (p<0.001). With the numbers available for this investigation, there were no significant differences found between groups in relation to surgeon, high-volume (>150 TKAs annually) or low-volume surgeons, length of stay, discharge disposition, or smoking status. Conclusion. MUA risk factors include a lower mean age, high cholesterol, African-American, surgeon fellowship training, and receiving a cruciate-retaining device

Introduction. Stiffness after total knee arthroplasty is a common occurrence. Despite its prevalence, little is known as to which patients are at risk for poor range of motion after total knee arthroplasty. The purpose of this study was to determine the risk factors for manipulation under anesthesia (MUA) after total knee arthroplasty (TKA). Methods. Using a single institution registry, 160 patients who underwent a manipulation under anesthesia after total knee arthroplasty between 2007 and 2013 were retrospectively evaluated. Each patient was 1:1 matched by age, gender and laterality to a control group of 160 patients who did not require MUA after TKA. Risk factors for MUA were assessed, and included medical co-morbidities, BMI, prior operations, and preoperative range of motion. Results. There were 160 patients in each group, 48 males and 112 females. Patients who required a MUA after TKA had a significantly higher percentage of overweight patients with a BMI >25 (88% vs 76%, p=0.01, Odds ratio=2.18), and previous surgery including arthroscopy (60% vs 33%, P < 0.0001, Odds ratio=3.12). Patients that underwent an MUA had a higher but not significant prevalence of depression and anxiety (22% vs. 16%, p=0.20, Odds Ratio=1.44) and diabetes (15% vs. 8%, p=0.058, Odds Ratio=2.0). Average ROM was 3–110° (Range −10–130°) and 6–102° (Range 0–140°) in the MUA and control groups respectively. In the MUA group, 29% of patients had pre-operative flexion less than 90 degrees pre-operatively compared to 3% in the control group (p=0.02, Odds Ratio=6.6). While the average preoperative range of motion did not differ between the groups, there were a larger percentage of patients with severe limitations in range of motion who ended up needing a MUA after TKA compared to controls. Conclusion. Patients with increased BMI, preoperative range of motion less than 90°, and a history of prior operations should be counseled on the increased risk of requiring a MUA after TKA

OBJECTIVE. Post TKR manipulation under anesthesia is required when post operatively patients don't achieve desired range of motion. The rates quoted in various western literature ranges from 1 to 2 %. A knee is considered to be stiff when the patient fails to achieve 60 degrees of flexion. The objective of the study was to find out the differentiating factor responsible for low rate of MUA in Indian post TKR patients as compared to Anglo-Saxon population. MATERIAL & METHODS. We studied 100 consecutive patients operated from January 2016. The following parameters of these 100 patients were recorded. Pre-op ROM. Age and Sex of the TKR patient. Duration of home physiotherapy. Post opROM. All patients received post operative physiotherapy at home every day for first 2 weeks, 3 times a week for next 2 weeks and then once a week for next two weeks. The implant used was Maxx Freedom knee (PS design). RESULTS. Of the 300 TKR patients 270 were females and 30 were males. The age range for male patients was 65 to 87 years with a mean of 73 years. The age range of female patients was 65 to 83 years with a mean of 71 years. The mean range of motion achieved was 121 degrees. Only one of our patient required manipulation under anesthesia.(0.333%). CONCLUSION. Our rate of MUA is totally different from that of reported from Western world. According to us home physiotherapy is the main differentiating factor responsible for this low rate. Hence we strongly advocate personalized home physiotherapy post TKR with constant feedback mechanism between the operating doctor and the treating physiotherapist

Introduction. Total knee arthroplasty is very successful although the clinical assessment and rated outcome does not always match the patients reported satisfaction. One reason for patient dissatisfaction is less than desired range of motion. Poor postoperative motion inhibits many functional activities and may create a perception of dysfunction. Early in the postoperative period when patients are having trouble regaining motion (usually 6–8 weeks), manipulation under anesthesia can be used to advance range of motion by manually lysing adhesions. Comorbidities have been used as predictors for outcome in total knee arthroplasty in population health studies. Likewise, predicting which patients are most susceptible to early postoperative stiffness/manipulation would be valuable for patient education and to predict outcome. Methods. Prospectively collected data was retrieved from the hospital's MARCQI database (Michigan Arthroplasty Collaborative Quality Initiative) for the years 2014–2018. There were 3098 primary total knees performed during the study period and 139 manipulations (4.44%). The registry specifically abstracts patients’ preoperative comorbidities, operative data, and 90-day postoperative complications. Results. There were 2118 Cruciate Retaining/Cruciate Stabilized knees (105 MUA), 801 Posterior Stabilized (33), and 41 Total Stabilized/Hinge (1), 2160 knees were cemented (91) and 799 uncemented (48). No differences were found between the manipulation and non-manipulation groups for gender, race, alcohol consumption, bleeding disorders, history of DVT or PE, Diabetes, or use of pre-op narcotics or anti-coagulents. Patients undergoing manipulation were younger (67.2 vs. 63.8, p= 0.00001), had a lower BMI (32.6 vs. 30.9 p= 0.0007), and were more likely to be non or former (quit) smokers. There were no differences noted for the constraint of the component (cr/ps), or whether the implants were cemented or uncemented (35% vs. 27%, p= 0.064). Conclusions. Understanding the risk for postoperative stiffness and the potential for manipulation is helpful in the preoperative period for patient education and outcome prediction. Assessing comorbidities and patient characteristics may help avoid the need for manipulations postoperatively. This patient cohort may be biased since the manipulations were not based on predetermined criteria. The cohort represents patients whose range of motion was poor enough to cause the surgeon to perform the procedure. The findings do however highlight a patient pool that was surprisingly at risk: younger, thinner, nonsmokers regardless the implant design or use of cement

Introduction. Arthrofibrosis remains a persistent complication following total knee arthroplasty (TKA). Although manipulation under anesthesia (MUA) is an effective early treatment, the risks and value of this procedure beyond 3 months after TKA remain controversial. The purpose of this study was to examine the safety and efficacy of late MUAs for arthrofibrosis. Methods. From our institutional total joint registry, 82 TKAs (77 patients) who underwent MUA >3 months after primary (83%) or revision (17%) TKA were identified. Mean time to MUA was 7 months: 66% performed between 4–6 months, 18% between 7–12 months, 16% beyond 12 months. MUAs were coupled with arthroscopic assistance in 26% (12% limited lysis of adhesions, 13% formal arthroscopic debridement). Mean age was 61 years, 59% females, and mean BMI was 33kg/m. 2. Mean follow-up was 5 years. Results. No fractures, extensor mechanism disruptions, or other complications related to late MUA occurred. The mean ROM gained after MUA was 18° (76° to 94°, p<0.001). Substantial ROM gains (≥20°) occurred in 50%, while 21% made no gains or lost ROM after MUA. ROM gains ≥20° occurred in 54% of primary TKAs and 28% of revision TKAs. While ROM gains were higher when performed between 3–6 months (21°) compared to 6–12 months (13°) and >12 months (11°), these differences did not reach statistical significance (p=0.26). No differences in mean ROM gains were observed in MUAs performed with or without arthroscopic assistance (19° versus 15°, p=0.54). Kaplan Meier survivorship free of repeat MUA and revision TKA were 85% and 80% at 20 years, respectively. Conclusion. Late MUA, coupled with arthroscopic assistance in selected patients, was safe in a broad range of stiff primary and revision TKAs with no fractures or extensor disruptions occurring. While mean ROM improvements were modest, a substantial subset of patients achieved clinically important ROM gains ≥20°. Summary. Late MUA substantially improved ROM in a subset of patients with stiff TKAs and was done safely. In selected patients, arthroscopic lysis of adhesions or formal debridement aided the perceived safety and efficacy

Introduction. Arthrofibrosis following total knee arthroplasty (TKA) is a complex and multifactorial complication that may require manipulation under anesthesia (MUA). However, patient and surgical factors that potentially influence the development of knee stiffness following TKA are not fully understood. The purpose of this study was to identify patient and surgical factors that may influence arthrofibrosis following TKA by assessing a cohort of patient that underwent MUA and comparing them to a matched cohort of patients without arthrofibrosis. Methods. The joints registry of a university hospital was searched for patient that underwent MUA following primary TKA between 2004 and 2013. Demographic and surgical information was obtained from the electronic medical record including range of motion (ROM), comorbidities and timing of MUA. Patients who underwent MUA were then double-matched by baseline (prior to primary TKA) knee ROM to patients who underwent primary TKA without postoperative arthrofibrosis during the same time period. Results. Fifty-two patients (56 TKAs, 71% female, mean BMI 32.2kg/m2) underwent MUA after TKA during the study period. MUA was performed a mean of 13.6 weeks after primary TKA. Study patient were then double-matched by baseline flexion (mean 107º±2º) to 111 patients (112 TKAs) with a similar mean baseline flexion (104º±2º, p=0.138). Patient requiring MUA were younger (mean age 56 vs. 64 years, p<0.001), had more comorbidities (5 vs. 3, p<0.001), and a higher number of previous knee surgery (56% vs. 21%, p<0.001) compared with controls. The risk for requiring MUA following primary TKA was significantly higher (2.4, p<0.001) in patient with previous knee surgery (arthroscopy for meniscal pathology, ACL reconstruction, osteotomies). Tourniquet time, length of stay, number of physical therapy sessions, blood loss >50 mL and any complication during the hospital stay were not found to be associated with increased risk of requiring MUA. Discussion. Younger patients with more comorbidities and a history of previous knee surgery were found to have significantly higher risk for developing arthrofibrosis and requiring MUA after primary TKA in the current study. Patients with this risk profile need to counseled regarding the risk for arthrofibrosis possibly requiring MUA after primary TKA

A reduced range of movement post total knee replacement (TKR) surgery is a well recognised problem. Manipulation under anaesthesia (MUA) is a commonly performed procedure in the stiff post operative TKR. Long term results have been variable in the literature. We prospectively followed up 48 patients since 1996 from one centre, over an average of 7.5 years, (range 1 to 10 years) and report on the long term results. The mean time to MUA post TKR was 12.3 weeks (range 3 to 48). Pre MUA, the mean flexion was 53°. The mean immediate passive flexion post MUA was 97°, an improvement of 44° (Range 10° to 90°, CI < 0.05). By one year, the mean flexion was 87°, improvement of 34°, (range −15° to 70°, CI< 0.05). At ten years the mean flexion was 86°. We found no difference between those knees manipulated before or after 12 weeks. In addition there was no difference found in those knees which had a pre TKR flexion of greater or less than 90°. There were no complications as a result of MUA. However, one patient was eventually revised at two years secondary to low grade infection. Our findings show that MUA is safe and effective method at improving the range of motion in a stiff post operative TKR. The improvement is maintained in the long term irrespective of time to MUA and range of motion pre TKR

Introduction. Manipulation under anesthesia (MUA) remains the gold standard to address restricted range of motion (ROM) within 3–6 months after primary total knee arthroplasty (TKA). However, there is little data on the outcomes of MUA with different types of anesthesia. We sought to compare the outcomes of patients undergoing MUA with intravenous (IV) sedation and neuraxial anesthesia. Methods. We identified 548 MUAs after primary TKA (136 IV sedation, 413 neuraxial anesthesia) at a single institution from 2016–2019. Mean age was 62 years and 349 patients (64%) were female. Mean body mass index was 32 kg/m. 2. The mean time from primary TKA to MUA was 10 weeks. Mean pre-MUA ROM was similar between each group; mean pre-MUA extension was 4.2° (p=0.35) and mean pre-MUA flexion was 77° (p=0.56). Patient demographics were statistically similar between both groups. We compared immediate complications, including fracture, extensor mechanism disruptions, and wound complications, Visual analogue pain scores (VAS), length of stay (LOS), and immediate and 3 month follow-up ROM between these groups. Results. No patients in either group sustained an immediate post-MUA complication. Patients undergoing MUA with IV sedation had significantly higher day of MUA average VAS of 5.1 compared to 4.1 in the neuraxial group (p<0.001). The average LOS was shorter in patients that received IV sedation (9 hours) compared to neuraxial anesthesia (12 hours) (p=0.009). Immediate-post MUA ROM was 1° – 121° in the IV sedation group and 0.9° – 123° in the neuraxial anesthesia group (p=0.21). Three month follow-up ROM was 2° – 108° in the IV sedation group and 1.9° – 110° in the neuraxial anesthesia group. Conclusion. IV sedation and neuraxial anesthesia are both effective anesthetic methods for patients undergoing MUA after primary TKA with minimal perioperative differences. Surgeons and anesthesiologists should cater anesthetic technique to patient specific needs as the orthopedic outcomes are similar for both methods; however, IV sedation resulted in a shorter LOS

BACKGROUND. The need for post-operative manipulation under anesthesia (MUA) for stiffness after primary total knee arthroplasty is a frustrating complication that can lead to suboptimal outcomes if range-of-motion to a functional level is not regained. Implant morphology and kinematics, PCL imbalance, and soft-tissue balancing can all contribute to post-operative stiffness. Utilization of total knee arthroplasty components that replicate the native knee's medial ball and socket kinematics may lead to easier maintenance of flexion post-operatively compared to conventional components. PURPOSE. To determine if a medial pivot total knee arthroplasty design can reduce the need for post-operative MUA after primary total knee arthroplasty. METHODS. A retrospective chart review of primary total knee arthroplasties performed between 2013 and 2016 by a single fellowship-trained joint replacement surgeon was performed. Cases that met criteria for inclusion were: primary total knee arthroplasty, identifiable implant based on operative report and/or post-operative radiographs, immediate post-operative passive flexion against gravity of at least 110 degrees, and availability of post-operative follow-up notes documenting range-of-motion that was either satisfactory or necessitating need for MUA. The need for a MUA was deemed necessary if post-operative flexion was not beyond 90 degrees within six weeks of surgery. The percentage of patients requiring MUA for a group implanted with the EVOLUTION Medial Pivot System was compared to a group implanted with all other designs (Stryker Triathlon CR, PS, TS). RESULTS. One hundred fifty-six cases met criteria for inclusion and were reviewed. The Triathlon system was used predominantly in the first half of the study period and accounted for 65 (42%) of the cases performed. Six patients in this group underwent MUA and two patients required repeated MUA. An additional patient in the Triathlon group met the criteria for MUA but had other conditions which prevented the investigators from performing it. The percentage of patients who met the indication for MUA in the Triathlon group was 10.8%. The EVOLUTION system was used predominantly in the second half of the study period and accounted for 91 (58%) of the cases performed. There were two patients (2.2%) who met criteria for MUA and both patients subsequently underwent MUA. There was a statistically significant reduction in the number of patients meeting criteria for MUA in the EVOLUTION group compared with the Triathlon group (p=0.024). CONCLUSION. Utilization of a medial ball and socket design for primary total knee arthroplasty allows the polyethylene implant to control the position of the femur on the tibia. This design possibly allows for improved early maintenance of post-operative flexion, which may minimize the need for post-operative MUA. For any figures or tables, please contact authors directly (see Info & Metrics tab above).

Hallux rigidus is the second most common pathological condition of the first metatarsophalangeal joint, after hallux valgus. Manipulation of the joint and injection with steroid and local anaesthetic (MUA and Injection) is widely practiced, but the literature contains little information on the results of such treatment. We report the results of this procedure performed on thirty-seven joints, with a minimum follow-up of 1 year (mean 41.2 months). Patients with mild (Grade I) changes gained symptomatic relief for a mean of 6 months and only one third required further surgery. Two thirds of patients with moderate (Grade II) disease proceeded to open surgery. In advanced (Grade III) hallux rigidus little symptomatic relief was obtained and all patients required operative treatment. We recommend that joints are Graded before treatment and that MUA and injection be used only in early (Grades I and II) hallux rigidus.

The August 2024 Research Roundup. 360. looks at: Effect of vitamin D deficiency on periprosthetic joint infection and complications after primary total joint replacement; Postoperative angiotensin receptor blocker use associated with decreased rates of manipulation under anaesthesia in patients undergoing total knee arthroplasty; Central sensitization: the missing link between psychological distress and poor outcome following primary total knee arthroplasty; Thromboprophylaxis for the trauma and orthopaedic surgeon; Life expectancy after treatment of metastatic bone disease: an international trend analysis

Aims. A pragmatic multicentre randomized controlled trial, UK FROzen Shoulder Trial (UK FROST), was conducted in the UK NHS comparing the cost-effectiveness of commonly used treatments for adults with primary frozen shoulder in secondary care. Methods. A cost utility analysis from the NHS perspective was performed. Differences between manipulation under anaesthesia (MUA), arthroscopic capsular release (ACR), and early structured physiotherapy plus steroid injection (ESP) in costs (2018 GBP price base) and quality adjusted life years (QALYs) at one year were used to estimate the cost-effectiveness of the treatments using regression methods. Results. ACR was £1,734 more costly than ESP ((95% confidence intervals (CIs) £1,529 to £1,938)) and £1,457 more costly than MUA (95% CI £1,283 to £1,632). MUA was £276 (95% CI £66 to £487) more expensive than ESP. Overall, ACR had worse QALYs compared with MUA (-0.0293; 95% CI -0.0616 to 0.0030) and MUA had better QALYs compared with ESP (0.0396; 95% CI -0.0008 to 0.0800). At a £20,000 per QALY willingness-to-pay threshold, MUA had the highest probability of being cost-effective (0.8632) then ESP (0.1366) and ACR (0.0002). The results were robust to sensitivity analyses. Conclusion. While ESP was less costly, MUA was the most cost-effective option. ACR was not cost-effective. Cite this article: Bone Jt Open 2021;2(8):685–695

Aims. This systematic review places a recently completed multicentre randomized controlled trial (RCT), UK FROST, in the context of existing randomized evidence for the management of primary frozen shoulder. UK FROST compared the effectiveness of pre-specified physiotherapy techniques with a steroid injection (PTSI), manipulation under anaesthesia (MUA) with a steroid injection, and arthroscopic capsular release (ACR). This review updates a 2012 review focusing on the effectiveness of MUA, ACR, hydrodilatation, and PTSI. Methods. MEDLINE, Embase, PEDro, Science Citation Index, Clinicaltrials.gov, CENTRAL, and the World Health Organization (WHO) International Clinical Trials Registry were searched up to December 2018. Reference lists of included studies were screened. No language restrictions applied. Eligible studies were RCTs comparing the effectiveness of MUA, ACR, PTSI, and hydrodilatation against each other, or supportive care or no treatment, for the management of primary frozen shoulder. Results. Nine RCTs were included. The primary outcome of patient-reported shoulder function at long-term follow-up (> 6 months and ≤ 12 months) was reported for five treatment comparisons across four studies. Standardized mean differences (SMD) were: ACR versus MUA: 0.21 (95% confidence interval (CI) 0.00 to 0.42), ACR versus supportive care: -0.13 (95% CI -1.10 to 0.83), and ACR versus PTSI: 0.33 (95% CI 0.07 to 0.59) and 0.25 (95% CI -0.34 to 0.85), all favouring ACR; MUA versus supportive care: 0 (95% CI -0.44 to 0.44) not favouring either; and MUA versus PTSI: 0.12 (95% CI -0.14 to 0.37) favouring MUA. None of these differences met the threshold of clinical significance agreed for the UK FROST and most confidence intervals included zero. Conclusion. The findings from a recent multicentre RCT provided the strongest evidence that, when compared with each other, neither PTSI, MUA, nor ACR are clinically superior. Evidence from smaller RCTs did not change this conclusion. The effectiveness of hydrodilatation based on four RCTs was inconclusive and there remains an evidence gap. Cite this article: Bone Jt Open 2021;2(9):773–784