Aims. To evaluate whether low-intensity pulsed ultrasound (LIPUS) accelerates bone healing at osteotomy sites and promotes functional recovery after open-wedge high tibial osteotomy (OWHTO). Methods. Overall, 90 patients who underwent OWHTO without bone grafting were enrolled in this nonrandomized retrospective study, and 45 patients treated with LIPUS were compared with 45 patients without LIPUS treatment in terms of bone healing and functional recovery postoperatively. Clinical evaluations, including the pain visual analogue scale (VAS) and Japanese Orthopaedic Association (JOA) score, were performed preoperatively as well as six weeks and three, six, and 12 months postoperatively. The progression rate of gap filling was evaluated using anteroposterior radiographs at six weeks and three, six, and 12 months postoperatively. Results. The pain VAS and JOA scores significantly improved after OWHTO in both groups. Although the LIPUS group had better pain scores at six weeks and three months postoperatively, there were no significant differences in JOA score between the groups. The lateral hinge united at six weeks postoperatively in 34 (75.6%) knees in the control group and in 33 (73.3%) knees in the LIPUS group. The progression rates of gap filling in the LIPUS group were 8.0%, 15.0%, 27.2%, and 46.0% at six weeks and three, six, and 12 months postoperatively, respectively, whereas in the control group at the same time points they were 7.7%, 15.2%, 26.3%, and 44.0%, respectively. There were no significant differences in the progression rate of gap filling between the groups. Conclusion. The present study demonstrated that LIPUS did not promote bone healing and functional recovery after OWHTO with a locking plate. The routine use of LIPUS after OWHTO was not recommended from the results of our study. Cite this article: Bone Jt Open 2022;3(11):885–893

Total knee arthroplasty (TKA) is becoming more prevalent as the average age of the general population increases and is generally considered to be a very effective and successful surgery. However, functional recovery post-surgery can often be less than optimal. Neuromuscular electrical stimulation (NMES) is a beneficial therapy proven to improve haemodynamics and muscle strength and may be of great benefit in improving functional recovery in the acute phase post-TKA. The objective of the study was to assess functional recovery in the period immediately following TKA and hospital discharge in response to a home-based NMES programme. Twenty-six TKA patients were randomized into a NMES stimulation or placebo-controlled group. All participants were given a research muscle stimulator to use at home post-discharge for 90 minutes per day over a period of 5 weeks. In the stimulation group, application of stimulation resulted in an electrically activated contraction of the soleus muscle. Patients in the placebo-controlled group received sensory stimulation only. Outcome measures were physical activity levels, joint range of motion and lower limb swelling, which were measured pre-surgery and on a weekly basis post-discharge up until the sixth post-surgical week. 90 minutes per day NMES stimulation significantly increased the Activity Time (P = 0.029 week 1 post-discharge) and the number of Stepping Bouts (P < 0.05 weeks 1 to 4 post-discharge) in the early post-discharge phase. While there was a trend towards a greater knee flexion with use of NMES, this did not reach statistical significance (P = 0.722). No effect of NMES was observed on swelling (P > 0.05 for all measures). Compliance to the NMES therapy was measured by an on-board SIM card in the NMES device, with a 95% and 94% time compliance rate for the stimulation and placebo-controlled groups respectively. The results of this study suggest that NMES may be very useful in improving functional recovery through increasing physical activity levels in the early post-TKA discharge phase. The results of this study warrant further investigation into the use of an optimized NMES protocol whereby improvements in knee range of motion and swelling may also be observed

Aims: The purpose of this study is to evaluate the functional recovery and mortality after the sequential fracture of both hips in elderly patients. Methods: Eight hundred forty-two patients (over 64 years of age) with hip fractures (nonpathologic) consecutively admitted to our hospital between January 1, 1999, and December 31, 2001, were included in this prospective study. A total of 765 were admitted of their þrst hip fracture, and the other 77 patients had a second contralateral fracture. All patients were identiþed at the time of admission, had fracture treatment and were followed untill six months or death. Information of complications and postinjury function was collected. Differences between the two groups were explored in contingency tables. Results: Most recurrent hip fractures (90%) are the same pattern the þrst contralateral fracture was. Functional recovery, postoperative complications and the length of stay of the patients affected by recurrent fracture were similar to the ones of the patients suffering from a single fracture. Hemoglobin level at admittance was 13 g/dl (mean) for single group and 12 g/dl (mean) for recurrent group; blood transfusion was needed for 30% from the single group and 50% from the recurrent group. Six months mortality was 17% for recurrent group and 28% for single group (p=0.033). Conclusions: Our data suggest that the functional recovery in elderly patients with hip fractures is not inßuenced by a previous fracture of the contralateral hip. Lower mortality after recurrent hip fracture shows us older patients and those with more concomitant diseases died before suffering the second fracture

The Pronator Quadratus (PQ) is commonly damaged in the surgical approach to the distal radius during volar plating. This study explored the functional strength of the PQ muscle, 12 months after volar plating of a distal radial fracture. Testing of treated and contralateral forearms was carried out using a custom-made Torque Measuring Device (TMD) and surface Electromyography (sEMG). To assess both the direct and indirect function of PQ in participants treated with volar plating and compared to the contralateral non-injured forearms. The angle of elbow flexion was varied from 45o, 90o and 135o when measuring forearm pronation. Mean peak torque of the major pronating muscles, PQ and Pronator Teres (PT) was directly measured with the TMD and the indirect activation of the PQ and PT was measured with sEMG. In total 27 participants were studied. A statistically significant reduction in mean peak pronation torque was observed in the volar plated forearms (P<0.05 SE 0.015, CI 95%). This is unlikely to be of clinical significance as the mean reduction was small (13.43Nm treated v 13.48Nm none treated). Pairwise comparison found no statistically significant reduction in peak torque between 45o, 90o and 135o of elbow flexion. There was an increase in PQ muscle activation at 135o compared to 45o elbow flexion. The converse was identified in PT. The small but statistically significant difference in mean peak torque in treated and uninjured forearms is unlikely to be of clinical significance and results suggest adequate functional recovery of the PQ after volar plating

Introduction and purpose: A large amount of studies discuss risk factors that lead to higher mortality and a worse functional recovery in patients who sustain a hip fracture, namely age, a previous pathology and gender. The purpose of this study is to determine what role is played by obesity in the evolution of this pathology. Materials and methods: This is a prospective study that includes all the patients older than 65 who were admitted to our hospital for a non-pathological hip fracture between 1999 and 2002. Of a total 1142 patients, 15.5% were obese (BMI> 30). No differences were detected as to the type of fracture, time to surgery or length of hospitalization. The group of obese patients required fewer postoperative blood transfusions since their postop hemoglobin levels were significantly higher than those of the other group. All patients were followed up for up to six months after having sustained the fracture or until exitus. Results: Mortality was 24% for the control group and 39.1% for obese patients. Significantly, this group also had a higher complications rate (pneumonias, deep venous thrombosis, pulmonary thromboembolism and digestive bleeding). Lastly, functional recovery took significantly less time. Conclusions: Vital and functional prognosis after sustaining a hip fracture is bleaker for obese patients. In our study we quantified it at a RR = 1.62 for mortality and at a RR=2.01 for poor functional recovery. The higher frequency of postop complications lead us to indicating more stringent prophylactic measures for these patients

Purpose. We explored the role of patients beliefs and attitudes towards their likelihood of recovery from severe physical trauma. Method. We developed and validated an instrument designed to capture the impact of patients beliefs and attitudes towards functional recovery from injury; the Somatic Pre-Occupation and Coping (SPOC) questionnaire. At six weeks post-surgical fixation, we administered the SPOC questionnaire to 359 consecutive patients with operatively managed tibial shaft fractures. We constructed multi-variable regression models to explore the association between SPOC scores and functional outcome at one year, as measured by return to work and Short Form-36 (SF-36) physical component summary (PCS) and mental component summary (MCS) scores. Results. In our adjusted regression models that included pre-injury SF-36 scores, SPOC scores at six weeks post-surgery accounted for 18% of the variation in SF-36 PCS scores and 18% of SF-36 MCS scores at one year. Our adjusted analysis found that for each 14-point increment in SPOC score (14 points being half the standard deviation of the aggregate score) at six weeks the odds of returning to work at 12 months decreased by 40% (odds ratio = 0.60; 95% CI = 0.50 to 0.73). In all models, six week SPOC scores were a far more powerful predictor of functional recovery than age, gender, fracture type, smoking status, or the presence of multi-trauma. Conclusion. The SPOC questionnaire is a valid measurement of illness beliefs and attitudes in tibial fracture patients and is highly predictive of their long-term functional recovery

Introduction. Total hip arthroplasty (THA) is undertaken to relieve pain and to restore mobility. The orthopaedic community remains divided on the influence of surgical approach in achieving functional recovery most quickly and effectively. We report a study comparing THA performed through a posterior (Posterior) against anterior approach (Heuter). Methods. Fifty patients were prospectively enrolled and randomized for Posterior or Heuter procedures. Informed patient consent and local ethics approval was obtained. All patients received an uncemented, ceramic-on-ceramic prosthesis performed by a single surgeon. Functional outcome was assessed by time to achieve milestones of walking, stair climbing, hip movement and balance. Kinematic data on level-ground walking and the effect of fatigue was assessed using a portable gait analysis system at 6-, 12-, and 24-weeks post-operatively. Results. The Heuter group showed significantly quicker balance control, on average 10 days earlier, than the posterior group (p< 0.05). The achievement of the other milestones of independent and distance walking, stair climbing and hip movement also showed quicker recovery overall in the Heuter group; this was, however, not statistically significant (p>0.05). Kinematic data suggested that there were no statistical differences in stance phase stability (p=0.73) or pulling acceleration (p=0.77) between the 2 groups at each time point. Fatigue, effected via timed, gentle mobilisation on a treadmill, also did not significantly result in a difference. Discussion. The Heuter approach is rarely used in the UK, although its recent resurgence can be attributed to its perceived theoretical benefit of sparing muscle; this contrasts with the detachment of muscle required for the Posterior approach. Our experience show that the Heuter approach does not compromise the quality of gait, and it offers advantages in the rate of functional recovery, especially that of balance control

Aims: To evaluate the functional recovery of the complex tibial plateau fractures Schatzker type V and VI treated with hybrid ex. fix. Methods: Twenty-eight patients with intra-articular fractures of the proximal tibia were treated with hybrid external fixation in a three years period (1998–2001).The mean age was 35 years (17–76). According to Schatzker classification, there were 11(39.3%) fractures type V and 17(60.7) type VI, whereas 5(17.8%) fractures were open. Complex injury was recorded in 15(53.5%) patients. Closed reduction and hybrid external fixation was achieved in 21 (75%) fractures. Additional limited internal fixation was performed in 9(32%) cases. Open reduction was necessary in 7(25%) patients. Mobilization of the injured articulation was started at the 3rd postoperative day. Results: Mean follow up period was 18 months. All fractures but one united at an average of 13.5 weeks (range from 11 to 18 weeks). The results were assessed according to the criteria of Honkonen and Jarvinen. An overall 22(78%) excellent and good results was recorded at the final follow up. Complications included one axial deformity, one septic pseudarthrosis, one peronial palsy and five pin tract infections. Conclusions: The use of hybrid external fixation in the comminuted tibial plateau fractures (Schatzker V,VI), insure good restraining and early union, avoid major soft tissue complications and allow early mobilization and functional recovery of the knee joint

The purpose of this study is to determine the indications and effectiveness of hybrid external fixation in the treatment of tibial plateau fractures and to evaluate the patient’s functional recovery. Twenty-seven patients with 28 intra-articular fractures of the proximal tibia were surgically treated with hybrid external fixation in a two years period (1999–2001). There were 25 patients (19 men and 6 women) available for the last follow up evaluation. The mean age was 35 years (17–76). According to Schatzker classification, there were 6 fractures type V and 22 type VI. Three of them were open fractures. The method included, indirect reduction based on ligamentotaxis and compression of the fractured segments with olive pins, in most patients. Additional limited internal fixation with free screws was also performed in 5 cases. Open reduction was necessary in 6 patients. Mobilization of the injured articulation was started at the third postoperative day, while full weight bearing was allowed after three months. The fixator was removed in average 12th week. Final evaluation was done according subjective, functional, clinical and radiological criteria. Mean follow up period was 14 months. All fractures except one united at an average time of 13, 5 weeks. Twenty-two patients (77.6%) graded as excellent and good, hi detail, subjective results were acceptable in 72%, functional in 84%, clinical in 70% and radiological in 80%. Complications included one axial deformity, one septic pseudarthrosis, one peronial palsy and superficial pin path infections. The use of hybrid external fixation in the comminuted tibial plateau fractures (Schatzker V, VI), insure good restraining and early union, avoid major soft tissue complications and allow quick mobilization and functional recovery of the knee joint. Moreover it is an application rather atraumatic because, only occasionally requires open reduction

Aims. We wished to assess the feasibility of a future randomised controlled trial of parathyroid hormone (PTH) supplements to aid healing of trochanteric fractures of the hip, by an open label prospective feasibility and pilot study with a nested qualitative sub study. This aimed to inform the design of a future powered study comparing the functional recovery after trochanteric hip fracture in patients undergoing standard care, versus those who undergo administration of subcutaneous injection of PTH for six weeks. Patients and Methods. We undertook a pilot study comparing the functional recovery after trochanteric hip fracture in patients 60 years or older, admitted with a trochanteric hip fracture, and potentially eligible to be randomised to either standard care or the administration of subcutaneous PTH for six weeks. Our desired outcomes were functional testing and measures to assess the feasibility and acceptability of the study. Results. A total of 724 patients were screened, of whom 143 (20%) were eligible for recruitment. Of these, 123 were approached and 29 (4%) elected to take part. However, seven patients did not complete the study. Compliance with the injections was 11 out of 15 (73%) showing the intervention to be acceptable and feasible in this patient population. Take home message: Only 4% of patients who met the inclusion criteria were both eligible and willing to consent to a study involving injections of PTH, so delivering this study on a large scale would carry challenges in recruitment and retention. Methodological and sample size planning would have to take this into account. PTH administration to patients to enhance fracture healing should still be considered experimental. Cite this article: Bone Joint J 2016;98-B:840–5

Aims: To evaluate the functional recovery of the complex tibial plateau fractures Schatzker type V and VI treated with hybrid ex. þx. Methods: Twenty-eight patients with intra-articular fractures of the proximal tibia were treated with hybrid external þxation in a three years period (1998–2001). The mean age was 35 years (17–76). According to Schatzker classiþcation, there were 11(39.3%) fractures type V and 17(60.7) type VI, whereas 5(17.8%) fractures were open. Complex injury was recorded in 15(53.5%) patients. Closed reduction and hybrid external þxation was achieved in 21 (75%) fractures. Additional limited internal þxation was performed in 9(32%) cases. Open reduction was necessary in 7(25%) patients. Mobilization of the injured articulation was started at the 3rd postoperative day. Results: Mean follow up period was 18 months. All fractures but one united at an average of 13.5 weeks (range from 11 to 18 weeks). The results were assessed according to the criteria of Honkonen and Jarvinen. An overall 22(78%) excellent and good results was recorded at the þnal follow up. Complications included one axial deformity, one septic pseudarthrosis, one peronial palsy and þve pin tract infections. Conclusions: The use of hybrid external þxation in the comminuted tibial plateau fractures (Schatzker V, VI), insure good restraining and early union, avoid major soft tissue complications and allow early mobilization and functional recovery of the knee joint

Objective. As the aging society progresses rapidly in Japan, the number of elderly patients underwent TKA is increasing. These elderly patients do not expect to do sports, but regain independency in the activity of daily living. Therefore, we measured basic ambulatory function quantitatively using 3m timed up and go (TUG) test. We clinically experienced patient with medially unstable knee after TKA was more likely to result in the unsatisfactory outcome. We hypothesized that post-operative knee stability influenced ambulatory function recovery after TKA. In this study, we evaluated ambulatory function and knee stability quantitatively, and analyzed the effect of knee stability on the ambulatory function recovery after TKA. Materials & Methods. Seventy nine patients with varus type osteoarthritic knees underwent TKA were subjected to this study. The mean age of surgery was 72.4 years old. Preoperative standing coronal deformity was 9.6 degrees in varus. TUG test results in less duration with faster ambulatory function. TUG (seconds) was measured at 3 time periods; pre-operatively, at hospital discharge and 1year after surgery. To standardize TUG recovery time during 1 year after TKA, we defined TUG recovery rate as the percentage of recovery time to the pre-operative TUG as shown in the following equation. TUG recovery rate (%) = (TUG pre-op –TUG 1y po) / TUG pre-op ×100. We also evaluated the knee stability at hospital discharge and 1year after surgery. The knee stability at extension and flexion were assessed by varus and valgus stress radiography using Telos (10kg) and stress epicondylar view with 1.5kg weight at the ankle respectively. Image analyzing software was used to measure joint separation distance (mm) at medial as medial joint opening (MJO) and at lateral as lateral joint opening (LJO) at both knee extension and flexion. (Fig.1). The sequential change of TUG was analyzed using repeated measures ANOVA (p<0.05). The influence of joint opening distances (MJO and LJO at extension and flexion) on TUG 1y po and TUG recovery rate were analyzed using simple linear regression analysis (p<0.05). Results. The mean TUGs were 13.4, 13.7 and 10.8 seconds pre-operatively, at hospital discharge and 1 year after TKA respectively. Significant decrease was found at 1 year after surgery. TUG pre-op did not show significant correlation to any joint openings. TUG 1y po was positively correlated with both flexion and extension MJO at hospital discharge. (Fig.2) TUG recovery rate negatively correlated to flexion-MJO at hospital discharge. (Fig.3). Discussions. The most interesting findings in the present study were that both flexion and extension MJO at hospital discharge were positively correlated with TUG 1y po and negatively correlated with TUG recovery rate. This indicated that early post-operative medial stability played an important role in the recovery of ambulatory function. The early post-operative medial instability would cause pain and deteriorate functional recovery after surgery. There is some disagreement regarding the importance of pursuing the perfect ligament balance, which would be more likely to result in medial instability. Consequently, surgeons should prioritize medial stability for better ambulatory functional recovery after TKA

Despite the variety of implants or techniques that exist to treat displaced distal radial fractures, the majority fail to provide sufficient stability to permit early functional recovery. However, locking plates have the advantage over other implants in that locking screws add considerably to the overall stability. The aim of this study was to assess the functional outcome of patients with displaced distal radial fractures treated with a volar distal radial locking plate (Synthes). During a two year period, details of 98 patients admitted to our unit with inherently unstable dorsally displaced distal radial fractures treated with volar locking plates were collected prospectively. For the purpose of this analysis, only those patients (55) with unilateral fracture, able to attend the study clinic at 6 months post-injury were considered. Patients were immobilised in wool and crepe for a 2 week period. The group consisted of 15 males and 40 females with an average age of 54 (28 to 83). At 6 months, patients' perceived functional recovery averaged 80%. Objective assessment was considered in relation to the uninjured side: grip strength 73%; pinch strength 83%; palmarflexion 77%, dorsiflexion 80%; radial deviation 74%; ulnar deviation 74%; pronation 93%, and supination 92%. Seven patients complained of symptoms relating to prominent metalwork. Good/excellent early subjective and objective functional recovery was made following open reduction and internal fixation using volar locking plates of dorsally displaced distal radial fractures. We suggest that objective assessment of grip strength and dorsiflexion can be used as a measure of patient perception of function

Aims. The objective of this study was to compare early postoperative functional outcomes and time to hospital discharge between conventional jig-based total knee arthroplasty (TKA) and robotic-arm assisted TKA. Patients and Methods. This prospective cohort study included 40 consecutive patients undergoing conventional jig-based TKA followed by 40 consecutive patients receiving robotic-arm assisted TKA. All surgical procedures were performed by a single surgeon using the medial parapatellar approach with identical implant designs and standardized postoperative inpatient rehabilitation. Inpatient functional outcomes and time to hospital discharge were collected in all study patients. Results. There were no systematic differences in baseline characteristics between the conventional jig-based TKA and robotic-arm assisted TKA treatment groups with respect to age (p = 0.32), gender (p = 0.50), body mass index (p = 0.17), American Society of Anesthesiologists score (p = 0.88), and preoperative haemoglobin level (p = 0.82). Robotic-arm assisted TKA was associated with reduced postoperative pain (p < 0.001), decreased analgesia requirements (p < 0.001), decreased reduction in postoperative haemoglobin levels (p < 0.001), shorter time to straight leg raise (p < 0.001), decreased number of physiotherapy sessions (p < 0.001) and improved maximum knee flexion at discharge (p < 0.001) compared with conventional jig-based TKA. Median time to hospital discharge in robotic-arm assisted TKA was 77 hours (interquartile range (IQR) 74 to 81) compared with 105 hours (IQR 98 to 126) in conventional jig-based TKA (p < 0.001). Conclusion. Robotic-arm assisted TKA was associated with decreased pain, improved early functional recovery and reduced time to hospital discharge compared with conventional jig-based TKA. Cite this article: Bone Joint J 2018;100-B:930–7

Aims. The aim of this study was to assess the effectiveness of perioperative essential amino acid (EAA) supplementation to prevent rectus femoris muscle atrophy and facilitate early recovery of function after total knee arthroplasty (TKA). Methods. The study involved 60 patients who underwent unilateral TKA for primary knee osteo-arthritis (OA). This was a double-blind, placebo-controlled, randomized control trial with patients randomly allocated to two groups, 30 patients each: the essential amino acid supplementation (9 g daily) and placebo (lactose powder, 9 g daily) groups. Supplementation and placebo were provided from one week before to two weeks after surgery. The area of the rectus femoris muscle were measured by ultrasound imaging one month before surgery and one, two, three, and four weeks postoperatively. The serum albumin level, a visual analogue knee pain score, and mobility were also measured at each time point. The time to recovery of activities of daily living (ADLs) was recorded. Postoperative nutrition and physiotherapy were identical in both groups. Results. The mean relative change from baseline was as follows for the amino acid group: 116% in rectus femoris muscle area (71% to 206%); 95% in serum albumin (80% to 115%) and 39% in VAS pain (0% to 100%) at four weeks after surgery. These values in the placebo group were: 97% in muscle area (68 to 155); 89% in serum albumin (71% to 100%) and 56% in VAS pain four weeks after surgery (0% to 100%). All changes were statistically significant (p < 0.05). The mean time to recovery of ADLs was shorter in the amino acid group compared with the placebo group (p = 0.005). Conclusion. Perioperative essential amino acid supplementation prevents rectus femoris muscle atrophy and accelerates early functional recovery after TKA. Cite this article: Bone Joint J 2020;102-B(6 Supple A):10–18

Introduction. Low serum Vitamin D (VitD) levels are often found in patients being investigated for Total Knee Arthroplasty (TKA). VitD deficiency is associated with poor pre/post-operative functional scores and higher rate of complications. Studies report VitD as an important modifiable risk factor to improve outcomes post TKA. Aim. Aim of our study was 1) To examine the trajectory of VitD in TKA patients over 2 weeks, which included VitD sufficient and deficient patients who were supplemented orally or intramuscularly (IM) for comparision. 2) To compare early (2weeks) functional recovery in VitD sufficient and deficient patients. Material & Methods. We prospectively enrolled patients undergoing primary TKA by a single surgeon. Based on preoperative VitD levels (25OH VitD ≥30 being sufficient or <30 ng/mL being deficient) and means of supplementation(none, IM or Oral Injection Arachitol, Cholecalciferol IP 6,00,000 IU), we formed three groups: Group A (VitD sufficient, no supplementation); Group B (VitD deficient, IM supplementation); and Group C (VitD deficient, Oral supplementation). Study was approved by ethics committee. All patients gave informed consent and underwent TKA by same surgeon with uniform intra/post-operative protocols. VitD deficiency was supplemented orally/IM on the morning of surgery based on their randomization sequence. VitD levels (ng/mL) and outcome parameters of Flexion (degrees) and Timed up-and-go (TUG) test in seconds were assessed preoperatively and postoperatively on Day 3 and 14. 60 patients (20 per group) were enrolled. Demographics of all three groups were comparable. Results. VitD:. Group A:. Mean preoperative level of 42.3, fell to mean 40.4 by Day 3 (p < 0.001), and further to mean 38.9 by Day 14 (p<0.001). 6 and 4 patients became VitD deficient by Day 3 and Day 14 respectively. Group B:. Mean preoperative level of 21.5 rose to 31.2 by Day 3 (p=0.06), and further to 36.9 by Day 14 (p=0.001). 7 and 11 patients became sufficient by Day 3 and Day 14 respectively. Group C:. Mean preoperative level of 20.2 rose to mean 69.9 by Day 3 (p<0.001) and to a mean of 67.2 by Day 14 (p < 0.001). 19 and 20 patients became sufficient by Day 3 and Day 14 respectively. Outcome. Flexion:. Preoperative Flexion in Groups A, B, C was 133, 129 & 125 respectively (p=0.5). Day 3 Flexion was 88, 84 & 83 (p=0.2); Day 14 Flexion was 99, 90 & 95 (p=0.013) respectively. Posthoc Schaffe test showed statistical significance (p<0.05) only between Group A (99) and Group B (90) at Day 14. This indicated better flexion achieved in VitD sufficient patients at 2 weeks than in deficient patients with IM supplementation. TUG Test. was 17.1, 14.1 & 14.7 preoperatively in Groups A, B, C (p=0.5); on Day 3, it was 52.5, 62.6 & 58.2 (p=0.07); on Day 14, it was 33, 38.8 & 37.8 (p=0.2) respectively. Day 3 TUG time was longest (62.6) in Group B and shortest (52.5) in Group A indicating that IM supplemented patients had poor function compared to sufficient group though without statistical significance (p=0.07) with numbers available. Conclusion. We found that VitD deficient patients can be rapidly supplemented on the morning of surgery. High dose oral VitD increased levels by Day 3, whereas IM VitD increased levels only by Day 14 which remained significantly lesser than oral group. Interestingly, about 25% of VitD sufficient patients who were not supplemented, became deficient postoperatively. Flexion achieved on Day 14 was significantly better with VitD sufficiency, compared to deficient patients treated with IM VitD. Significance. VitD deficiency can be rapidly corrected by high dose oral supplementation on the morning of surgery. Also, TKA can deplete VitD and can make VitD sufficient patients deficient as early as Day 3 post surgery. For figures, tables, or references, please contact authors directly

115 patients undergoing primary unilateral THA were randomized to either DAA or MPA. Groups did not differ in mean age, sex, or mean body mass index. Functional results included time to discontinue gait aids, discontinue all narcotics, and independence with various activities of daily living. Activity in study subjects was measured with 5 wearable activity monitoring sensors with tri-axial MEMS accelerometers and validated custom algorithms and conducted over three days at pre-op, 2 weeks, 8 weeks, and one year. SF-12, WOMAC, and HHS scores to one year were also tabulated. Early functional recovery slightly favoured DAA compared to MPA; time to discontinue walker (10 vs. 14.5 days), time to discontinue all gait aids (17.3 vs 23.6 days), ascend stairs with gait aid (5.4 vs. 10.3 days), and to walk 6 blocks (20.5 vs. 26.0 days). There were no other differences in early functional milestones. Activity monitoring at two weeks postoperatively slightly favoured DAA; mean steps per day were 3897 versus MPA 2,235, percent of day active, DAA 10.5% versus MPA 6.9%. There was no difference in activity monitoring pre-operatively, at two months, or at one year. There was no difference at one year with the SF-12. There was no difference in the SF-12 mental component or the HOOS at any time point. There was no loosening or subsidence of any of the components in any hip. Both the direct anterior and posterior approach provided excellent early postoperative recovery with a low complication rate. The direct anterior patients had slightly faster recovery than the mini-posterior approach patients, with slightly shorter times to achieve milestones of function and as measured by advanced, quantitative activity monitoring at 2 weeks postoperatively

INTRODUCTION. Motion analysis is routinely used in the clinical and research sectors to quantify joint biomechanics. It plays an important role in clinical assessments by aiding the physician to distinguish between primary movement abnormalities and any secondary compensatory mechanisms that may overshadow the cause of the problem. During a data collection session, a wealth of biomechanical data regarding joint and segment kinematics and kinetics are collected from patients performing daily activities. Objective classification can be used to automate a diagnosis from this data and has been used previously to analyse measurements of level gait [1]. It is of interest to assess the knee during stair-gait as this activity involves greater range of motion (ROM) of the lower limbs, larger forces and moments acting at the knee. AIM. The aim of the current study is to explore the use of an objective classifier [1] to characterise knee osteoarthritis (OA) and monitor functional recovery following a total knee replacement (TKR) using measurements from stair-gait. METHODS. Motion analysis techniques were used to quantify knee OA kinematics and kinetics during stair-gait for six patients with knee osteoarthritis (OA) and nine subjects without pathology (NP). One OA subject, forming a TKR sample, was also assessed at 4, 8 and 12 post-operatively. Each subject performed three trials of stair ascent and descent. 3D motion capture was performed using 8 Qualisys MCUs, capturing at 60Hz and a 1000Hz force plate (Bertec Corporation). Forces were measured from the first step of the staircase [2]. Independent t-tests were performed on biomechanical measures to compare the NP and OA cohorts (p<0.05). This identified the adaptations associated with knee OA. Principal components of salient kinematic and kinetic waveforms were used as inputs to train the classifier and subsequently characterise recovery of the TKR sample. RESULTS. The OA cohort adapted their stair-gait by reducing their peak: (i) external flexion moment in stance during both stair ascent and descent; (ii) medial ground reaction force (GRF) (iii) vertical GRF during stair descent and increasing their external adduction moment during stair ascent. The classifier was used to characterise knee function of the OA and NP subjects with 100% classification accuracy, defined using a Leave-one-out cross-validation. The TKR sample was classified as having dominant OA functional characteristics pre-operatively. At all subsequent measurements the subject was classified as having NP stair-gait characteristics. These changes correlated significantly with Knee Outcome Survey and Oxford Knee scores. CONCLUSION. Classification is a powerful tool for characterising data into two groups where a simplex plot provides a simple clinical interpretation of the results from a motion analysis assessment. This study demonstrates the use of objective classification to quantify NP, OA and TKR function from stair-gait. It also demonstrates its capability to monitor functional changes during a subject's recovery

Older fracture patients frequently ask whether their osteoporosis will affect fracture healing. There is only limited previous data about this. We investigated recovery after distal radial fracture, and compared it with BMD of the other distal radius and the lumbar spine (measured using quantitative CT). All 28 patients had sustained a dorsally displaced distal radial fracture which was deemed to require treatment by intrafocal wire fixation. All patients had acceptable correction of dorsal and radial angle at final x ray (3 months). Wrist function was measured using the Patient Rated Wrist Evaluation (PRWE – a validated outcome measure for use after distal radial fractures), grip strength,and range of motion. All measurements were made at 6, 12 and 26 weeks. BMD was measured in the opposite wrist and the lumbar spine using QCT at 6 weeks after fracture. There was no correlation between recovery of grip strength (% of contralateral grip strength) at 6,12,or 26 weeks with BMD at either site. Similarly, there was no correlation between BMD and either absolute PRWE scores at any time point or improvement in PRWE between time points. The strongest predictor of recovery of grip appeared to be the proportion of grip recovered at 6 weeks (correlation between% grip recovered at 6 weeks and 3 months r = 0.85; at 6 weeks and 6 months r= 0.56; both p < 0.001). This was not affected by age or variations in measured final dorsal or radial angles or length within this group. It was not affected by degree of preoperative fracture displacement. These data suggest that recovery of function after distal radial fractures is not influenced by osteoporosis. The data about the importance of initial recovery of grip suggest that factors other than bone position and bone healing may affect rate of functional recovery after distal radial fracture

Introduction. Rapid increase of aged population has been one of major issue affecting national health care plan in Japan. In 2006, Japanese Orthopaedic Association proposed the clinical entity of musculoskeletal ambulation disorder symptom complex (MADS) to define the elderly population with high risk of fall and ambulatory disability caused by musculoskeletal disorders. Osteoarthritis of the knee is one of major cause of MADS. The number of patients with MADS underwent total knee arthroplasty (TKA) had been increased in Japan, and also expected to increase worldwide in the near future. The effectiveness of TKA for the patient with MADS has not been well evaluated. In the present study, we analyzed the early post-operative functional recovery after TKA using 2 simple performance tests to diagnose MADS. Material & Method. Fifty patients with varus type osteoarthritic knees implanted with posterior-stabilized (PS) TKAs were subjected to this study. There were 44 female and 6 male patients. The mean age of the patients was 71.6 years (range, 59 to 84 years). Patients were subjected to 2 functional performance tests which were essential tests for MADS diagnosis. Firstly, 3 meter timed up and go test (TUG) was used to evaluate ambulation. Secondary one leg standing time with open eyes was measured to assess balancing ability. 2 tests were performed pre-operatively, 2 weeks after surgery and at discharge (23.8 days po). MADS was defined to be diagnosed if TUG and one leg standing time was not less than 11 seconds and/or less than 15 seconds respectively. Each parameter was compared among at above mentioned three time points -using a repeated measured analysis of variance (p<0.05). Results. The number of the patients with MADS were 37, 44 and 38 in 50 patient pre-operatively, 2 weeks after surgery and at hospital discharge respectively. Mean TUG was 12.9, 16.9 and 14.0 sec. respectively [fig 1]. TUG significantly increased during 2 weeks after TKA, followed by significant decrease at discharge. There were no significant improvements in ambulation during hospital stay. Mean one leg standing time with operated and non-operated side leg at three time points were 11.0, 12.4, 17.9 sec, and 18.4, 17.9, 24.2 sec. each respectively [fig 2]. There were no significant improvements during initial 2 weeks after surgery. Significant increase of one leg standing time was found after 2 weeks, and balancing ability was found to be improved during hospital stay. Discussion & Conclusion. Although both parameters assessing ambulatory and balancing function were found to be improved post-operative 2 weeks, still as much as 76% of patients were suffered from MADS at hospital discharge in our patient population. These results indicate that the patient after TKA has still exposed to high risk of fall and ambulatory dysfunction at discharge. We should reconsider the appropriate rehabilitation protocol especially for the elderly patient with MADS to meet with patient expectation and enhance early post-operative care