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The Bone & Joint Journal
Vol. 106-B, Issue 3 | Pages 256 - 261
1 Mar 2024
Goodall R Borsky K Harrison CJ Welck M Malhotra K Rodrigues JN

Aims

The Manchester-Oxford Foot Questionnaire (MOxFQ) is an anatomically specific patient-reported outcome measure (PROM) currently used to assess a wide variety of foot and ankle pathology. It consists of 16 items across three subscales measuring distinct but related traits: walking/standing ability, pain, and social interaction. It is the most used foot and ankle PROM in the UK. Initial MOxFQ validation involved analysis of 100 individuals undergoing hallux valgus surgery. This project aimed to establish whether an individual’s response to the MOxFQ varies with anatomical region of disease (measurement invariance), and to explore structural validity of the factor structure (subscale items) of the MOxFQ.

Methods

This was a single-centre, prospective cohort study involving 6,637 patients (mean age 52 years (SD 17.79)) presenting with a wide range of foot and ankle pathologies between January 2013 and December 2021. To assess whether the MOxFQ responses vary by anatomical region of foot and ankle disease, we performed multigroup confirmatory factor analysis. To assess the structural validity of the subscale items, exploratory and confirmatory factor analyses were performed.


Bone & Joint Open
Vol. 3, Issue 6 | Pages 455 - 462
6 Jun 2022
Nwankwo H Mason J Costa ML Parsons N Redmond A Parsons H Haque A Kearney RS

Aims

To compare the cost-utility of removable brace compared with cast in the management of adult patients with ankle fracture.

Methods

A within-trial economic evaluation conducted from the UK NHS and personnel social services (PSS) perspective. Health resources and quality-of-life data were collected as part of the Ankle Injury Rehabilitation (AIR) multicentre, randomized controlled trial over a 12-month period using trial case report forms and patient-completed questionnaires. Cost-utility analysis was estimated in terms of the incremental cost per quality adjusted life year (QALY) gained. Estimate uncertainty was explored by bootstrapping, visualized on the incremental cost-effectiveness ratio plane. Net monetary benefit and probability of cost-effectiveness were evaluated at a range of willingness-to-pay thresholds and visualized graphically.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIII | Pages 3 - 3
1 Sep 2012
Hakim Z James M Lattouf G Shoaib A
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Introduction. Morton's Neuroma is routinely treated by excision of the interdigital nerve. Traditional surgery works by denervation, but the results are variable, and recurrence is common. Multiple Morton's Neuromas present a difficult clinical challenge. MR and ultrasound often demonstrate a normal nerve or an interdigital bursa. Some experts advise division of the intermetatarsal ligament rather than excision. This case series evaluates an alternative method of treatment. Methods. Patients with a clinical diagnosis of Morton's Neuroma, with symptoms only on weight bearing, were treated with division of the intermetatarsal ligaments and Weil's osteotomies. The nerve was not excised. Patients wore a postoperative shoe for six weeks. If radiographs were satisfactory, they returned to weight bearing in a normal shoe. They were evaluated at 12 weeks with AOFAS scoring, as part of the routine clinical pathway. Results. 14 patients were treated with Weil's osteotomy, including one who had recurrence of symptoms following traditional surgery. The mean AOFAS score rose from 71 to 91. No patient had recurrent symptoms after surgery. The patient who had previously been treated with excision of the nerve also had some improvement. Discussion. The success of this surgery in relief of symptoms in this case series raises questions about the pathology, diagnosis and treatment of Morton's Neuroma. Many MR studies find abnormal nerves in asymptomatic patients, and no neuroma in symptomatic patients. Patients have symptoms exacerbated by weight bearing, and nerve compression may play an important part in the pathophysiology. Weil's osteotomy works by decreasing the effective weight bearing in the involved rays. It is particularly useful if symptoms exist in multiple intermetatarsal areas. Conclusions. Multiple Weil's osteotomies are an effective method for treatment of Morton's Neuroma. The basis for the traditional approach of excision of the nerve may be flawed and merits further study


Bone & Joint Open
Vol. 2, Issue 4 | Pages 216 - 226
1 Apr 2021
Mangwani J Malhotra K Houchen-Wolloff L Mason L

Aims

The primary objective was to determine the incidence of COVID-19 infection and 30-day mortality in patients undergoing foot and ankle surgery during the global pandemic. Secondary objectives were to determine if there was a change in infection and complication profile with changes introduced in practice.

Methods

This UK-based multicentre retrospective national audit studied foot and ankle patients who underwent surgery between 13 January and 31 July 2020, examining time periods pre-UK national lockdown, during lockdown (23 March to 11 May 2020), and post-lockdown. All adult patients undergoing foot and ankle surgery in an operating theatre during the study period were included. A total of 43 centres in England, Scotland, Wales, and Northern Ireland participated. Variables recorded included demographic data, surgical data, comorbidity data, COVID-19 and mortality rates, complications, and infection rates.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIII | Pages 65 - 65
1 Sep 2012
Singh V Parthipun A Sott A
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Aim. Single-photon emission computed tomography is a new imaging modality combining high detail CT with highly sensitive triple phase nuclear bone scanning to help clinicians in diagnosis and management of various conditions. Little has been published about its particular usefulness in foot and ankle pathology. We conducted a prospective study to evaluate the role of SPECT for the same. Material and Methods. Fifty patients were seen in a tertiary referral foot and ankle clinic presenting with a variety of foot and ankle conditions. SPECT-CT was requested when a definitive clinical diagnosis could not be reached after thorough clinical examination and plain radiography. Pathology shown by SPECT-CT was taken as the final diagnosis and interventional surgical management carried out accordingly. Patients were subsequently seen in the follow up clinic to evaluate the outcome of their treatment. Results. In eleven (22%) cases, clinical correlation matched with the findings of the SPECT-CT and no change in treatment was necessary. However, in 39 patients (78%) findings of SPECT-CT did not correlate exactly with clinical findings and led to a modified treatment plan. Of these 39 patients, 35 (88%) improved after the intervention based on SPECT-CT findings. Conclusions. We found SPECT-CT to be a very useful investigation in complex foot and ankle cases where definite diagnosis after clinical and simple radiographic examination was still somewhat unclear. Our study suggests that SPECT-CT helps clinical decision making and improves outcome


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXII | Pages 76 - 76
1 May 2012
Ciapryna M Palmer S Alvey J
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Background. Morton's Neuroma is a proximal neuralgia that affects the web spaces of the toes and is currently of unknown aetiology. Currently surgical excision is considered the gold standard treatment based on RCT and cohort studies. However patient derived outcomes have not previously been assessed. We addressed these aspects with our study. Methods. The validadated patient derived Manchester Oxford Foot and Ankle Questionnaire (MOXFQ) was used to assess patient derived outcomes of surgery prospectively. The MOXFQ enables the generation of four scores, a combined global score as well as a pain, walking and social score. Participants were asked to fill out the 16 item questionnaire prior to surgery and were followed up after a minimum of 6 months. All participants were treated with neurectomy following clinical diagnosis. Results. 3 patients (13.6%) were lost to follow up. Final Cohort: 19 feet from 17 participants (F=16, M=1), mean age of 56. The mean reduction in the total MOXFQ score was significant (p=0.001). The pre surgical mean score was 38.1 (95% confidence interval = 33.4 - 42.8) and after a mean follow up period of 20 months was 13.1 (95% confidence interval = 7.5 – 18.6). The reductions observed in the three metric scores of pain, walking and social were all significant (p=0.005, p=0.008, p=0.006 respectively). Eighty four percent of patients in the study experienced a clinically significantly improved pain domain, 95% in the walking domain and 58% in the social domain of the MOXFQ. Conclusions. Surgical excision is an effective intervention for treating Morton's interdigital Neuroma with improvements seen in all three domains of the MOXFQ. The pain metric scores were consistent with previous studies. Neurectomy produces excellent functional improvements for patients. However patient derived social outcomes from surgical excision were slightly more modest than for those of pain and walking


The Bone & Joint Journal
Vol. 98-B, Issue 4 | Pages 498 - 503
1 Apr 2016
Mahadevan D Attwal M Bhatt R Bhatia M

Aims

The objective of this double-blind randomised controlled trial was to assess whether ultrasound guidance improved the efficacy of corticosteroid injections for Morton’s neuroma (MN).

Patients and Methods

In all, 50 feet (40 patients) were recruited for this study but five feet were excluded due to the patients declining further participation. The mean age of the remaining 36 patients (45 feet) was 57.8 years (standard deviation (sd) 12.9) with a female preponderance (33F:12M). All patients were followed-up for 12 months. Treatment was randomised to an ultrasound guided (Group A) or non-ultrasound guided (Group B) injection of 40 mg triamcinolone acetonide and 2 ml 1% lignocaine, following ultrasound confirmation of the diagnosis.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 5 | Pages 646 - 650
1 May 2010
Healy B Beasley R Weatherall M

We report an audit of 208 patients with a mean age of 39 years (16 to 65) attending the Orthopaedic Assessment Unit at the Wellington Hospital between January 2006 and December 2007 with an injury of the tendo Achillis requiring immobilisation in a cast. Information on assessment of venous thromboembolism (VTE) risk, prophylactic measures and VTE events for all patients was obtained from the medical records. A VTE risk factor was documented in the records of three (1%) patients. One of the 208 patients received aspirin prophylaxis; none received low molecular weight heparin. In all, 13 patients (6.3%, 95% confidence interval 3.4 to 10.5) developed symptomatic VTE during immobilisation in a cast, including six with a distal deep-vein thrombosis (DVT), four with a proximal DVT, and three with a confirmed pulmonary embolus. This incidence of symptomatic VTE is similar to that reported following elective hip replacement.

We propose that consideration is given to VTE prophylaxis during prolonged immobilisation of the lower limbs in a cast, to ensure that the same level of protection is provided as for patients undergoing elective hip replacement.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 8 | Pages 1055 - 1059
1 Aug 2007
Schock HJ Pinzur M Manion L Stover M

Supination-external rotation (SER) fractures of the ankle may present with a medial ligamentous injury that is not apparent on the initial radiographs. A cadaver gravity-stress view has been described, but the manual-stress view is considered to be the examination of choice for the diagnosis of medial injuries. We prospectively compared the efficacy of these two examinations.

We undertook both examinations in 29 patients with SER fractures. Of these, 16 (55%) were stress-positive, i.e. and had widening of the medial clear space of > 4 mm with a mean medial clear space of 6.09 mm (4.4 to 8.1) on gravity-stress and 5.81 mm (4.0 to 8.2) on manual-stress examination, and 13 patients (45%) were stress-negative with a mean medial clear space of 3.91 mm (3.3 to 5.1) and 3.61 mm (2.6 to 4.5) on examination of gravity- and manual-stress respectively. The mean absolute visual analgoue scale score for discomfort in the examination of gravity stress was 3.45 (1 to 6) and in the manual-stress procedure 6.14 (3 to 10).

We have shown that examination of gravity-stress is as reliable and perceived as more comfortable than that of manual stress. We recommend using it as the initial diagnostic screening examination for the detection of occult medial ligamentous injuries in SER fractures of the ankle.