The purposes of this study were to review retrospectively the 25-year survival of cemented and cementless THA for hip dysplasia and to compare the effect of fixation methods on the long-term survival in patients with DDH. We retrospectively reviewed all patients with OA secondary to hip dysplasia treated with a cemented Bioceram hip system between 1981 and 1987, and a cementless cancellous metal Lübeck hip system between 1987 and 1991. The studied subjects were 76 hips of cemented THA (Group-C) and 57 hips of cementless THA (Group-UC). Both hip implants had a 28-mm alumina head on polyethylene articulation. The mean age at operation was 50.5 years (range, 36–60 years) in Group-C and 50.0 years (range, 29–60 years) in Group-UC. The survival at 25 years regarding any revision as the endpoint was 46% in Group-C and 76% in Group-UC. These difference was significant using Log-rank test (P=0.008). The cup survival at 25 years was 47% in Group-C and 83% in Group-UC (P= 0.0003). The stem survivals at 25 years were 95% in Group-C and 92% in Group-UC. (P= 0.416). Cementless THA in patients with DDH showed a higher survival rate at 25 years than cemented THA because of the excellent survival of the acetabular component without cement. We conclude that cementless THA with the cancellous metal Lübeck hip system led to better longevity at 25 years than cemented THA with the Bioceram in patients with OA secondary to DDH

Introduction. Long term results of Total Hip Arthroplasty (THA) are affected by wear of articulation. Ceramic on ceramic articulation have been used especially for young patients because of its low wear and bio-inert property. However, because of its hardness, it is concerned that ceramic fracture, chipping, or squeaking might happen with ceramic on ceramic articulation. Objective. The purpose of this study was to investigate over 10-years clinical and radiographic results of ceramic bearing cementless THA. Methods. Evaluation was performed in 60 patients (68 joints) who underwent primary cementless THA from May 2003 to April 2007. Mean age at surgery was 59 years. Mean follow up period was 11.2 years. Forty-nine patients were female. Mean BMI at surgery was 24.0 kg/m. 2. Fifty-one patients had osteoarthrosis, 6 patients had osteonecrosis, 2 patients had rheumatoid arthraitis, and 1 patient had PSS. A 28mm-size femoral head was used in all patients. Clinical evaluation was performed with Japanese Orthopaedic Association Hip Score (JOA score). Radiographic results were evaluated with standard bilateral hip radiograph in supine position. Results. Mean clinical score at surgery was 45 (pain: 13/40, ROM: 12/20, gait: 9/20, ADL: 12/20). Mean clinical score at final follow up was 92 (pain: 39/40, ROM: 17/20, gait: 17/20, ADL: 18/20). Pain score was dramatically improved from 13 to 39 (maximum pain score: 40). One stem was revised because of recurrent dislocation. Two other patients experienced one time dislocation during follow up. One stem showed 5mm of subsidence. ALL cups and stems showed bone ingrowth at final follow up. Cortical hypertrophy was seen in 17 joints. However, there was no patient complained thigh pain. Stress shielding was seen in 55 joints (81%). First, second and third degree of stress shielding were seen in 12, 40, and 3 joints, respectively. Most of the female patients who had surgery at the age over 60 years showed second and third degree of stress shielding. There was no measurable wear. No osteolysis was found around the implants. There were no ceramic fracture, chipping, and squeaking. Conclusion. This study demonstrated excellent clinical and radiographic results of ceramic bearing cementless THA. Excellent long term results will be expected with this system

Introduction:. The outcome of previous cemented total hip arthroplasty has been reported to be inferior in renal transplant patients because of poor bone stock resulting from long-term steroid use. Moreover, as renal transplant patients remain on immunosuppressant therapy for life, higher levels of overall morbidity must be considered. We evaluated the mid-term results of cementless total hip arthroplasty in renal transplant recipients with osteonecrosis of the femoral head, and compared those with age and sex matched osteonecrosis patients that had not undergone organ transplantation or been treated with long-term steroid. Materials & Methods:. Between October 1997 and October 2008, 45 consecutive primary cementless total hip arthroplasties were performed in 30 patients with advanced osteonecrosis of the femoral head after renal transplantation. There were 18 males (27 hips) and 12 females (18 hips) of overall mean age 44 years (22 to 68). The clinical and radiographic results of cementless total hip arthroplasty in these 45 hips were compared with those of 96 sex and age-matched osteonecrotic hips of 72 patients that had not undergone organ transplantation or long-term steroid use. Patients were evaluated at surgery and at a mean of 7.2 years (range, 2–13 years) postoperatively. Results:. The mean Harris hip score of patients improved from 48 points preoperatively to 94 points at last follow-up (p < 0.05). Three hips in patient group had massive osteolysis with polyethylene wear requiring revision surgery. One hip in the patient group underwent revision surgery because of recurrent dislocation at 11 years postoperatively. No intergroup differences in overall rates of complications or revisions were observed. However, patients had a significantly higher rate of ectopic ossification. Conclusion:. Despite diffuse osteopenia and chronic immunosuppression in renal transplant patients with osteonecrotic hips, contemporary cementless total hip arthroplasty showed durable implant fixation to bone and did not increase complications

Introduction. The success of cementless total hip arthroplasty (THA) depends on the primary stability of the components. One of the biomechanical factors that comes into play is the mechanical quality of the bone. To our knowledge, there are no reported studies in the literature analyzing the impact of the preoperative bone mineral density on the outcomes of cementless THA. The goal of the study was to analyze the clinical results at 2 year follow-up according to the preoperative cancellous bone mineral density (BD). Our hypothesis was that the clinical outcomes were correlated to the BD. Material and methods. From January to June 2013, a prospective study included patients who underwent a cementless THA using a proximally shortly fixed anatomic stem. A 3D preoperative CTscan-based planning was performed according to the routine protocol using the Hip-Plan software in order to determine the hip reconstruction goals as well as the implants size and position. The Hounsfield bone density (BD) of the metaphyseal cancellous bone was computed in a volume (of 1 mm thick and of 1cm² surface) at the level of the calcar 10 mm above the top of the lesser trochanter and laterally to the medial cortical (Figure 1). Intra-and inter-observer repeatability measurements were performed. Patients were clinically assessed at 2 years follow-up using self-administered auto-questionnaires corresponding to the Harris and the Oxford scores. A Multivariate statistical analysis assessed correlations between clinical scores, age, gender, body mass index, and BD. Results. 50 patients were included consisting of 29 men and 21 women, with an average age of 62 ± 12 years and an average BMI of 25.8. The average preoperative BD was 69.4 ± 54 HU. At 2 years follow-up, the hip function scores were significantly correlated with the preoperative BD (0.42, p = 0.002) and the age (0.39, p = 0.005). However, there was no significant correlation between BD and BMI. Discussion Bone density appears to be an important parameter to consider when planning THA. This highlights also the importance of preoperative image calibration. Conclusion. The functional outcomes after cementless THA are correlated with preoperative cancellous bone density. Bone density needs to be integrated into THA 3D planning

Total hip arthroplasty (THA) is frequently performed as a salvage procedure for the acetabular fracture when posttraumatic osteoarthritis, posttraumatic avascular necrosis, or fixation failure with subluxation develop. Special considerations for this situation include previous surgical exposure with dense scar tissue, the type and location of implants, the location and amount of heterotopic ossification, indolent infection, previous sciatic nerve palsy, and the pathoanatomy of existing acetabular defect. These factors can influence the choice of surgical exposure and the reconstructive method. The outcomes of THA after acetabular fracture are generally less favorable than those of the nontraumatic degenerative arthritis. Reason for this high failure is the low mean age and the high activity level of the patient. Other important reasons for failure include the problem of acetabular bone deficiency and compromised bone quality. We evaluated the results of cementless THA in patient who had previous acetabular fracture. We also compared this result with those of patients with posttraumatic avascular necrosis of the femoral head. Forty-five consecutive cementless THAs were performed for the treatment of post-traumatic osteoarthritis after acetabular fracture between December 1993 and December 2008. Of these patients, 15 patients were died or lost to follow-up monitoring before the end of the minimum one year follow-up period. This left 30 patients (30 hips) as the subjects of our retrospective review. We evaluated the clinical and radiographic results of these patients and compared with the results of THA in patients with post-traumatic AVN of the femoral head which had without acetabular damage. Two hips required revision of the cup secondary to early migration of the acetabular cup (1 hip) and postoperative deep infection (1 hip). There was no significant difference in clinical and radiographic results between two groups except implanted acetabular component size and required bone graft (p<0.05). The Kaplan-Meier ten-year survival rate, with revision as the end-point, was 90% and 96.7% with loosening of acetabular component as the end-point. Our series suggested that compared with cemented components, uncemented sockets may improve the results of arthroplasty after previous acetabular fracture. In conclusion, cementless THA following acetabular fracture presents unique challenge to the surgeon, careful preoperative assessment and secure component fixation with proper bone grafting is essential to minimize problems

Although there are several reports of excellent long-term survival after cemented total hip arthroplasty (THA), cemented acetabular components are prone to become loose when compared with femoral components. On the other hand, the survival of cementless acetabular components has been reported to be equal or better than cemented ones and the use of cementless acetabular components is increasing. However, most of the reports on survival after THA are for patients with primary hip osteoarthritis (OA) and there is no report of 20-year survival of cementless THA for patients with hip dysplasia. It is supposed to be more difficult to fix cementless acetabular components for OA secondary to hip dysplasia than primary OA. The purposes of this study were to review retrospectively the 20-year survival of cemented and cementless THA for hip dysplasia and to compare the effect of fixation methods on the long-term survival for patients with hip dysplasia. We retrospectively reviewed all patients with OA secondary to hip dysplasia treated with a cemented Bioceram hip system between 1981 and 1987, and a cementless cancellous metal Lübeck hip system between 1987 and 1991. We excluded patients aged more than 60 years, males, and Crowe 4 hips. The studied subjects were 70 hips of cemented THA (Group-C) and 57 hips of cementless THA (Group-UC). Both hip implants had a 28-mm alumina head on polyethylene articulation. The mean age at operation was 50.5 years (range, 36–60 years) in Group-C and 50.0 years (range, 29–60 years) in Group-UC. The mean BMI was 23.2 kg/m. 2. in Group-C (range, 17.3–29.3 kg/m. 2. ) and 22.9 kg/m. 2. in Group-UC (range, 18.8–28.0 kg/m. 2. ). There were no significant differences in age and BMI between the two groups. The average follow-up period was 18.0 years in Group-C and 18.4 years in Group-UC. In Group-C, revision was performed in 33 hips due to aseptic cup loosening (30 hips), stem loosening (one hip), and loosening of both components (two hips). In Group-UC, revision was performed in 10 hips due to stem fracture secondary to distal fixation (4 hips), cup loosening (three hips), polyethylene breakage (two hips), and extensive osteolysis around the stem (one hip). The survival at 20 years regarding any revision as the endpoint was 51% in Group-C and 84% in Group-UC. This difference was significant using Log-rank test (P=0.006). The cup survival at 20 years was 54% in Group-C and 92% in Group-UC. This difference was also significant (P = 0.0003). The stem survival at 20 years was 95% in Group-C and 92% in Group-UC. This difference was not significant (P = 0.4826). Cementless THA showed a higher survival rate at 20 years for hip dysplasia than cemented THA because of the excellent survival of the acetabular component without cement. We conclude that cementless THA with the cancellous metal Lübeck hip system led to better longevity at 20 years than cemented THA with the Bioceram for patients with OA secondary to hip dysplasia

Introduction. Preoperative planning is an essential procedure for successful total hip arthroplasty. Many studies reported lower accuracy of two-dimensional analogue or digital templating for developmentally dysplastic hips (DDH). There have been few studies regarding the utility of three-dimensional (3D) templating for DDH. The aim of the present study is to assess the accuracy and reliability of 3D templating of cementless THA for hip dysplasia. Methods. We used 86 sets of 3D-CT data of 84 patients who underwent consecutive cementless THA using an anatomical stem and a rim-enlarged cup. There were six men and 78 women with the mean age of 58 years. The diagnosis was developmental dysplasia in 70 hips and osteonecrosis in 14 hips and primary osteoarthritis in 2 hips. There were 53 hips in Crowe group I, 11 hips in Crowe group II and 6 hips in Crowe group III. Each operator performed 3D templating prior surgery using a planning workstation of CT-based navigation system. Planned-versus-achieved accuracy was evaluated. The templating results were categorized as either exact size or +/− 1 size of implanted size. To assess the intra- and inter-planner reliabilities, 3D templating was performed by two authors blinded to surgery twice at an interval of one month. Kappa values were calculated. The accuracy and the intra- and inter-planner reliabilities were compared between the DDH group (70 hips) and the non DDH group (16 hips). Results. There was no significant difference in accuracy of component sizes between the DDH group and the non-DDH group. The accuracy of templating for cup sizes was 76 % for DDH and 75 % for non-DDH group (p=0.95). If accuracy was expanded to include all cups within one size of the implanted size, the accuracy was 97 % and 94 %, respectively (p=0.51). The accuracy of templating for stem sizes was 60 % for the DDH group and 75 % for the non-DDH group (p=0.27). The accuracy within 1 size was 99 % and 94 %, respectively (p=0.25). Regarding intra-planner reliability, mean kappa value for the cup size was 0.67 in the DDH group and 0.81 for the non-DDH group (p=0.18). Mean kappa value for the stem size was 0.64 in the DDH group and 0.79 for the non-DDH group (p=0.18). There were no significant differences in intra-planner reliability between the DDH and non-DDH group. Regarding inter-planner reliability for the cup size, mean kappa value was 0.33 in the DDH group and 0.37 in the non-DDH group (p=0.14). Mean kappa value for the stem size was 0.46 in the DDH group and 0.69 in the non-DDH group (p=0.07). There were no significant differences in inter-planner reliability between the DDH and non-DDH group. Conclusion. The 3D templating for cementless THA was accurate for hip dysplasia. Intra- and inter-planner reliabilities of the 3D templating were comparable with those of other primary diagnosis, while intra-planner reliability of cup sizes was fair regardless of diagnosis

Background. Nutrient arteries appear as radiolucent lines (Fig. 1) on account of their topography and may erroneously suggest fracture lines. Question/purpose. (1) How frequently the nutrient artery canals of the femur are seen after cementless THA and their distribution patterns are; (2) How to distinguish visible nutrient artery canal from fracture lines; and (3) Whether clinical significance of the nutrient artery canals of the femur in patients with primary cementless THA is evident or not. Methods. Between March 2010 and December 2013, 93 patients 102 hips were enrolled for this retrospective analysis. The number, location, direction of obliquity, length of the nutrient artery canals of the femur, the distance between the tip of the greater trochanter and the proximal end of the nutrient artery canal were measured. Results. The nutrient artery canal of the femur in the cortex on preoperative cross-table lateral hip radiograph (NACL) was seen in 32 of 102 hips (31.4%), the nutrient artery canal of the femur in the medullary cavity on preoperative anteroposterior hip radiograph (NAMA) was seen in 17 hips (16.6%), and the nutrient artery canal of the femur in the medullary cavity on preoperative cross-table lateral hip radiograph (NAML) was seen in 5 hips (4.9%). The nutrient artery canal of the femur in the cortex on anteroposterior hip radiograph was not seen at all. Entire visible NACLs coursed upward obliquely from postero-distal to antero-proximal direction. An average length of NACL was 32.6 ± 13.9 mm and an average distance between the tip of the greater trochanter and the proximal end of the NACL, NAMA and NAML was 130.1 ± 15.8 mm, 105.1 ± 13.4 mm and 102.5 ± 7.4 mm, respectively. NACL was seen postoperatively in 37 of 102 hips (36.3%), in 24 of which (23.5% overall) both ends of the nutrient artery canal were distal to the implant tip and in 13 of which (12.8% overall) one of the ends of the nutrient canal was at least proximal to the implant tip. NAMA was seen postoperatively in 8 of 102 hips (7.8%) and NAML was seen postoperatively in 6 hips (5.9%), in 5 of which (4.9% overall) femoral stems fully masked the nutrient artery canal and in 9 of which (8.8% overall) a nutrient artery canal was visible postoperatively, but its proximal end was not defined because of implant shadowing. The length of stems which fully masked the nutrient artery canals postoperatively were at least 150 mm or larger. Six (5.9%) intraoperative periprosthethic femoral fractures were detected (Fig. 2 and 3). One was type TL, one was type A1, three were type B2 and one was type B3. Type B2 fractures showed new or additional radiolucent lines on intraoperative and/or postoperative radiographs by comparison with the preoperative radiographs. Conclusions. The knowledge of radiographic features of the nutrient artery canals of the femur may be useful to distinguish them from intraoperative fractures after cementless THA

Total hip arthroplasty (THA) is associated with high intraoperative and postoperative blood loss. Antifibrinolytic drugs have been used to minimize the potential risks of bleeding and blood transfusion. Studies on the effect of tranexamic acid on decreasing blood loss in THA have revealed interesting results, but most have focused on cemented THA. Yet its benefits in THA, especially in cementless THA, have not been proved. We conducted a prospective double-blind randomized controlled study on 64 patients who were candidates for cementless THA under epidural anesthesia between 2006 and 2008. Patients were randomly assigned into study and control groups. Patients in both groups were well matched regarding preoperative characteristics. Five minutes preoperatively 32 patients of the study and control groups received 15 mg/kg tranexamic acid or normal saline intravenously respectively. Our findings showed a significantly smaller decrease in 6- and 24-hour postoperative hemoglobin levels, less intraoperative and postoperative bleeding, and less need for allogenic blood transfusion in the tranexamic acid group. Our results also revealed a higher mean of 6- and 24-hour hematocrit level and shorter hospital stay in the tranexamic acid group compared to the control group, which were not statistically meaningful. In our study no thromboembolic event was seen; except 1 patient in the control group. Our study showed that administering tranexamic acid before the start of cementless THA under epidural anesthesia can reduce intraoperative and postoperative bleeding as well as need for blood transfusion

Background. Although thigh pain is an annoying problem after total hip arthroplasty (THA), little information has been known about its natural course. Methods. To determine the frequency, time of onset, and duration of thigh pain after cementless THA, we evaluated 240 patients (240 hips) who underwent primary THA because of femoral head osteonecrosis with the use of a single tapered stem. Results. Twenty-seven patients (11.3%) experienced thigh pain during the follow-up of 3–11 years(mean, 84 months). The pain developed 2–78 months (median, 25 months) after THA. The 75% of pain developed within 36 months. In 25 patients, the pain disappeared postoperatively 1 month-64 months (mean, 17.4 months), and 2 patients (7.4%, 2/27) had persistent thigh pain. There were no differences in the latest Harris Hip Score between the thigh pain group and no thigh pain group. Conclusion. Our results provided basic information about the natural history of thigh pain after cementless THA with a tapered stem design

The study aims to compare the short-term results of cemented and cementless total hip arthroplasty {THA} in active patients > 80 years of age with femoral neck fractures. Sixty two consecutive patients underwent THA during the study period {cemented -31 and cementless -31}. The mean age was 84 years {81–94 years}. Patients in both groups were comparable in their preoperative variables. Functional and radiological assessments were carried out using validated outcome measures. Complications were recorded. 51 patients were available for final analysis after accounting for deaths and cases lost in follow up. Of the 51 patients, 25 {49%} regained their pre-injury mobility status and 36 {70%} were community ambulant. Cementless THA was associated with significantly less surgical time, blood loss, transfusion rates and hospital stay. The overall mortality rates, complications, functional and radiological results were similar in both groups though the number of deaths in the perioperative period were significantly high in patients undergoing cemented THA. Satisfactory improvement in function with low reoperation rates can be achieved irrespective of the technique used. Complication rates are higher when compared to younger patients undergoing the procedure. Risks and benefits should be carefully assessed and explained before subjecting these patients to THA

‘Getting It Right First Time’ guidance recommends the universal use of cemented prostheses in patients aged over 65 within the UK. This cut off has since been raised to 70. The report claims that the increased cost of uncemented technology is not justifiable in terms of patient outcomes. Our aim was to evaluate any disparity between patients across these age thresholds, in terms of functional outcomes, complication and costs following elective uncemented THR.

We utilised a single surgeon prospectively updated database, to compare functional outcome of patients aged over and under 65 and again at 70 following elective uncemented THR. We measured functional outcome using Oxford Hip Score (OHS). Patients were followed routinely for up to 2 years and subsequently up to 6 years.

Patient ages ranged from 23–89. Over 97% of patients reported an improvement in hip function, with an average increase of 24.1 in OHS. There was no statistical significance between patient age and functional hip outcome, p=0.108 with a cut off at 65 and p=0229 at 70. 1.1% of under 65s required revision surgery, compared to 2.3% of over 65s. 1.4% of patients under 70 required revision surgery, compared to 2.5% in those above. The most common reason for revision surgery was debridement, antibiotics and implant retention. Patients under 65 had a 1.4% chance of experiencing a fracture or dislocation, compared to 2.5% of patients over 65. 2.0% of patients under 70 experienced a fracture or dislocation, in comparison to 2.2% in those over 70. There was 1 recorded mortality, a patient aged over 70. Cost analysis is challenging accounting for all variables between techniques. Cementing invariably requires additional operating time and diminished theatre efficiency, with direct cost estimated at £364 in theatre running fees per case.

Within the series, uncemented THRs was found to be a safe and efficacious procedure irrespective of age. Functional hip outcome was not correlated to patient age, conflicting with GIRFT recommendations. The extra duration of cemented surgery may equilibrate the financial disparity of uncemented practice.

Background. Polyethylene wear in both cemented and uncemented total hip arthroplasty (THA) lead to generation of particles with their access to the interface which has been responsible for periprosthetic osteolysis and subsequent loosening of cup and stem. Many studies have been published studying the pattern of polyethylene wear and its relation to the type of implant (cemented/ uncemented cup or ceramic/metal head) used. No study in our knowledge has strictly focused on the effect of cemented versus uncemented stem on the polyethylene wear rates. We tried to compare the polyethylene wear rates reckoned with software (Poly Ware REV 7) of ultra high molecular weight polyethylene (UHMWPE) in hybrid and uncemented THA and its effect on complications of total hip replacements. Method. We retrospectively reviewed pre-matched 56 patients in uncemented group with 112 patients in hybrid group on the basis of polyethylene wear rate, revision rates and clinical issues, with mean follow up of 9.42 and 7.25 years (yrs.) respectively. Results. Mean polyethylene wear rate in uncemented group was 0.048 milli metres per year (mm/yr.) and it was 0.082 mm/yr. in hybrid. Wear rate in hybrid group ceramic head (0.072mm/yr.) was significant when compared to wear rate ceramic head in uncemented group (0.053mm/yr.), also we found significant difference of poly wear in the metallic group as well. There was no difference in stem loosening and cup osteolysis in low wear (<.05 mm/yr.) and high wear group (>.05mm/yr.) in both uncemented and hybrid THA. Conclusion. The revision was significantly higher in uncemented group but when adjusted with the age, it is equivocal. We found significant difference in polyethylene wear rates, but no significant difference in clinical performance and revisions among the two groups of uncemented THA and hybrid THA when compared on a mid-term 8 to 10 yrs. Follow up. Keywords. Total Hip Arthroplasty; Polywear; Uncemented THA; Hybrid THA

Introduction. The optimal bearing for hip arthroplasty is still a matter of debate. in younger and more active patients ceramic-on-polyethylene (CoP) bearings are frequently chosen over metal-on-polyethylene (MoP) bearings to reduce wear and increase biocompatibility. However, the fracture risk of ceramic heads is higher than that of metal heads. This can cause serious issue, as ceramic fractures pose a serious complication often necessitating major revision surgery – a complication more frequently seen in ceramic-on-ceramic bearings. To date, there are no long-term data (> 20 years of follow-up) reporting fracture rates of the ceramic femoral heads in CoP bearings. Patients and Methods. We retrospectively evaluated the clinical and radiographic results of 348 cementless THAs treated with 2nd generation Biolox® Al2O3 Ceramic-on-Polyethylene (CoP) bearings, which had been consecutively implanted between January 1985 and December 1989. At implantation the mean patient age was 57 years. The cohort was subsequently followed for a minimum of 20 years. At the final follow-up 111 patients had died, and 5 were lost to follow-up (Fig. 1). A Kaplan-Meier survivorship analysis was used to estimate the cumulative incidence of ceramic head fractures over the long-term. Results. (Figs. 2, 3):. After 22-years the cumulative incidence of ceramic head fracture was estimated at 0.3% (95%-CI, 0–2.4%; 38 hips at risk). No impending failures could be noted on radiographic analysis at final follow-up. Discussion. The fracture rate of second-generation ceramic heads using a CoP articulation remains very low into the third decade after cementless THA; ceramic heads appear to be a safe alternative to metal femoral heads. Summary. This study evaluates the long-term (20–25 year) survivorship of cement on polyethylene bearings in uncemented THA

Introduction and Aims. The 21. st. Century has seen ceramic bearings become an increasingly popular choice in total hip arthroplasty due to their high wear resistance and inert wear debris without osteolysis promising a long term bearing solution. Early ceramic bearings were hindered by fracture but improved manufacturing processes and materials subsequently produced stronger ceramics. These third generation ceramics showed greatly reduced fracture rates but there is limited evidence in the literature reporting their long term survival and wear characteristics. The purpose of this study was to determine osteolysis and survival rates of Alumina ceramic bearings in cementless total hip arthroplasties with a minimum follow-up of 15 years. Methods. We analyzed a series of 301 third-generation alumina-on-alumina cementless primary total hip replacements in 283 patients. The average age of the patients at the time of the arthroplasty was fifty-eight years, 51% were in women and 54% were right sided. All procedures were performed using the same surgical technique and the same implant at a single centre. Patients were followed up at six weeks, one, two, five, ten and 15 years. At 15 years postoperatively 46 patients (17%) had died of unrelated causes and 31 (10.2%) were lost to follow-up. Patients were assessed clinically and radiographically. Retrieved bearings were analyzed for wear. Results. At the time of the latest follow-up the mean Harris Hip Score was 94 points and 97% of the patients scored an excellent or good result with less than 4% having moderate residual pain. Radiographically, all patients assessed had evidence of stable bony ingrowth. Minor osteolysis was seen adjacent to 4% of cups and in none of the stems. There were eleven revisions in all, four stem revisions due to periprosthetic fracture, one secondary to aseptic loosening and one to facilitate a femoral shortening osteotomy. One cup was revised for aseptic loosening and one cup was revised for soft tissue impingement. One cup underwent revision due to acetabular osteolysis due to metallosis with some ceramic wear caused by neck impingement. There were two revisions for ceramic fracture, one liner and one femoral head. Overall, the survival rate of the implants for any cause revision was 96% at 15 years, with. The rate of survival of both components, with revision because of aseptic loosening or osteolysis as the end point, was 99% at 15 years. Analysis of retrieved femoral heads identified a median wear rate of 0.2mm3/year. Conclusion. Ceramic bearings were designed to overcome the problem of osteolysis due to wear from polyethylene bearings. This study has shown that Alumina bearings in cementless primary total hip arthroplasty have an excellent survival rate at 15 years with good function, low wear rate and no adverse radiographic changes typical of osteolysis. The fracture rate was low in our study. These findings strongly supporting the use of Ceramic as a bearing choice for the 21. st. Century

Femoral stem design affects periprosthetic bone mineral density (BMD), which may impact long term survival of cementless implants in total hip arthroplasty (THA). The aim of this study was to examine proximal femoral BMD in three morphologically different uncemented femoral stems designs to investigate whether one particular design resulted in improved preservation of BMDMethods: 119 patients were randomised to receive either a proximally coated dual taper wedge stem, a proximally coated anatomic stem or a fully coated collarless triple tapered stem. All surgeries were performed via the posterior approach with mobilization on the day of surgery. Dual energy x-ray absorptiometry scans (Lunar iDXA, GE Healthcare, Madison, WI) assessed BMD across the seven Gruen zones pre-operatively, and post-operatively at 6-weeks, 1-year, and 2-years and compared to the unoperated contralateral femur as a control. Patient reported outcome measures of pain, function and health were also included at these corresponding follow-ups.

BMD increased in zones one (2.5%), two (17.1%), three (13.0%), five (10%) and six (17.9%) for all stems. Greater preservation of BMD was measured on the lateral cortex (zone 2) for both the dual taper wedge and anatomic stems (p = 0.019). The dual taper wedge stem also demonstrated preservation of BMD in the medial calcar (zone 7) whilst the anatomic and triple taper stem declined in this region, however this was not statistically significant (p = 0.059). BMD decreased on average by 2.1% inthe mid-diaphysis region, distal to the stem tip (zone 4) for all implants. All stems performed equivalently at final follow-up in all patient reported outcome measures.

This study demonstrated maintenance of femoral BMD in three different cementless femoral stem designs, with all achieving excellent improvements in patient reported outcomes. There was no significant stress shielding observed, however longer follow-up is required to elucidate the impact of this finding on implant survivorship.

Background. Subtrochanteric femoral shortening and corrective osteotomy are considered to be an integral part of total hip arthroplasty for a completely dislocated hip or severe deformity of the proximal femur. A number of alternative femoral osteotomy techniques, transverse, oblique, step-cut, and V-shaped, have been described. Becker and Gustilo reported the “double-chevron subtrochanteric shortening derotational femoral osteotomy,” which is reasonable in that the osteotomy site is torsionally more stable and can be stabilized with a shorter stem. We have simplified this procedure, and performed it without a trochanteric osteotomy. We describe a simplified double-chevron osteotomy and provide the clinical results from a series of 22 successful procedures. Methods. In this series, we performed 22 cementless total hip arthroplasties combined with double-chevron subtrochanteric osteotomies between 1997 and 2002. There were 17 females and 2 males. Their average age at the time of the operation was 59 years old (range, 41–74 years old). Thirteen of these hips were congenitally dislocated hips (Crowe IV), and 8 hips were after proximal femoral osteotomies using a procedure described by Schanz or valgus osteotomy, and 1 hip was an ankylosed hip in malposition. Results. The mean length of the operation was 128 minutes (range, 80–215 minutes). The mean total blood loss was 1442 g (range, 809–2007 g), which included both the intraoperative blood loss and postoperative blood loss. After an average of 7.6 years of follow-up, the Japanese Orthopaedic Association Hip Score improved from 48 to 79. The mean amount of intraoperative femoral resection was 29 mm (range, 10–45 mm). The postoperative highest point of the greater trochanter was lowered by a mean of 50 mm (range, 6–74 mm) compared with its preoperative point on the radiograph. The calculated measurement (lowered greater trochanter minus intraoperative femoral resection) of leg lengthening was a mean 21 mm (range, −4–51 mm). Two acetabular component migrated, and one case required revision surgery. The other components showed no evidence of migration or loosening. There were radiolucent lines of less than 2 mm thickness in zones 1, 2, and 3 in one acetabular as previously mentioned revision case. One femoral component had subsidence 3 mm. Four femoral components had radiolucencies. One osteotomy site failed union and was varus deformity. After 6 years after the operation, the case required revision using cementless long stem. All femoral components achieved fixation with an optimal interface at the latest follow-up. Three types of complications were observed. There were no cases of neurologic abnormality, infection. There were 4 early dislocations, 3 proximal splits, and 1 nonunion at the osteotomy site. All femoral fragment fractures during the operation and all dislocations after the operation were in the Crowe IV group. Conclusions. Our study shows that double-chevron subtrochanteric osteotomy provided acceptable results for subtrochanteric femoral shortening and corrective osteotomy. The operation procedure is simple and the operation time is much shorter. However, THA combined with subtrochanteric osteotomy is a technically demanding treatment option

A prospective, randomized, double-blind study was done on 50 patients undergoing primary cementless total hip arthroplasty to determine the effect of tranexamic acid on intra- and postoperative blood losses and on the transfusions requirements. 50 patients were randomized to tranexamic acid (15 mg/kg) given as a bolus intravenous injection or placebo (normal saline) given intravenously, 15 minutes before the incision. The intraoperative and postoperative blood loss (at removal of the drain 24 hours after the operation) and the number of blood transfusions required were recorded. The patients were screened for deep venous thrombosis with bilateral compression Ultrasonography using Colour Doppler imaging on the tenth postoperative day. The Hemoglobin level was measured preoperatively and on the 3rd postoperative day. The D-dimer levels were measured preoperatively and 24 hrs postoperatively. Patients receiving tranexamic acid had a mean intraoperative blood loss of 410 ml (range, 300–510 ml) versus 615 ml (range, 515–750ml) (p value<0.05) in patients receiving placebo, a postoperative blood loss of 210 ml(range, 150–325ml) versus 490 ml(range, 370–540ml) (p value<0.05), and a total need for 8 blood transfusions versus 30. Only 6 out 25 patients in tranexamic acid group required blood transfusion whereas 18 out of 25 patients in the placebo group required transfusion. In the group receiving placebo the mean fall in hemoglobin was 2.9g/dl (range, 2.5–3.2) and in the group treated with tranexamic acid 1.6 g/dl (1.3–2) (p<0.05). At 24 hrs postoperatively, mean plasma D-dimer concentration in the Tranexamic group was half of that in the control group. No patient in either group had any evidence of deep vein thrombosis on bilateral compression Ultrasonography using Colour Doppler imaging done on the tenth postoperative day. Tranexamic acid 15 mg/kg given as a single preoperative bolus dose reduces peroperative and postoperative and total blood loss, and transfusion requirements in primary cementless total hip replacement surgery without any increased risk of thrombus formation

A prospective, randomized, double-blind study was done on 50 patients undergoing primary cementless total hip arthroplasty to determine the effect of tranexamic acid on intra- and postoperative blood losses and on the transfusions requirements. 50 patients were randomized to tranexamic acid (15 mg/kg) given as a bolus intravenous injection or placebo (normal saline) given intravenously, 15 minutes before the incision. The intraoperative and postoperative blood loss (at removal of the drain 24 hours after the operation) and the number of blood transfusions required were recorded. The patients were screened for deep venous thrombosis with bilateral compression Ultrasonography using Colour Doppler imaging on the tenth postoperative day. The Haemoglobin level was measured preoperatively and on the 3rd postoperative day. The D-dimer levels were measured preoperatively and 24 hrs postoperatively. Patients receiving tranexamic acid had a mean intraoperative blood loss of 410 ml (range, 300-510 ml) versus 615 ml (range, 515-750ml) (p value<0.05) in patients receiving placebo, a postoperative blood loss of 210 ml(range, 150-325ml) versus 490 ml(range,370-540ml) (p value<0.05), and a total need for 8 blood transfusions versus 30. Only 6 out 25 patients in tranexamic acid group required blood transfusion whereas 18 out of 25 patients in the placebo group required transfusion. In the group receiving placebo the mean fall in haemoglobin was 2.9g/dl (range, 2.5-3.2) and in the group treated with tranexamic acid 1.6 g/dl (1.3-2) (p<0.05). At 24 hrs postoperatively, mean plasma D-dimer concentration in the Tranexamic group was half of that in the control group. No patient in either group had any evidence of deep vein thrombosis on bilateral compression Ultrasonography using Colour Doppler imaging done on the tenth postoperative day. Tranexamic acid 15 mg/kg given as a single preoperative bolus dose reduces peroperative and postoperative and total blood loss, and transfusion requirements in primary cementless total hip replacement surgery without any increased risk of thrombus formation

Introduction:. Demand for total hip arthroplasty (THA) continues to rise and as such there is a concurrent presumed increase in the incidence of periprosthetic femoral fractures. Several studies have previously demonstrated differences in fixation technique and biomechanical advantages of various cerclage constructs in fixation of femoral periprosthetic fractures. The purpose of this study is to determine the most effective combination of cerclage materials and technique in fixation of of periprosthetic fractures during cementless THA. Methods:. Thirty fourth generation synthetic femora were tested in axial compression and torsion. Femurs were placed in a standardized mount and a press fit hip prosthesis was implanted by one senior surgeon. After broaching but prior to implant placement, a band saw was used to create a Vancouver B1 fracture below the level of the lesser trochanter. The implant was then placed in the femur. Four different cerclage constructs were then created using two of the following: 1) hose clamp, 2) metallic cable, 3) synthetic cable, 4) monofilament wire. All cables were placed using tensioning devices to standardize final cerclage tension. Additional constructs were created increasing the number of cerclage cables/wires to three and then four, evenly spaced across the implant. Axial compression and torsion were assessed to failure for all constructs using standard Instrom testing criteria. Cost analysis was performed for each construct. Results:. Data suggests that Construct 1 demonstrated superior results in both axial compression and torsion in all trials, increasing with the number of clamps used. Construct 4 demonstrated inferior results in both axial compression and torsion, although increasing the number of wires significantly increased the strength of the construct. Construct 2 and 3 were equivalent. Conclusion:. Increasing the number of cerclage cables/wires significantly increases the strength of the construct in both axial compression and torsion. Overall strength in order of strongest to weakest is as follows: hose clamp, metallic cable, synthetic cable and monofilament wire. It is reasonable to consider monofilament wires as a viable fixation option given lower cost and overall strength at physiologic loads