Advertisement for orthosearch.org.uk
Results 1 - 20 of 90
Results per page:
Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 445 - 446
1 Apr 2004
Powles DP Aston WJS
Full Access

Object: To determine whether moderate bone loss in revision total knee arthroplasty can be corrected using an uncemented prosthesis combined with cancellous bone grafting. Methods and results: 23 revision total knee replacements for aseptic loosening or sepsis were undertaken by the senior author between May 1999 and August 2002. All cases involved bone loss of grades F2 and or T2 according to the Anderson Orthopaedic Research Institute Classification (Engh 1998). Bone loss was treated with a mixture of morselized autograft, morselized allograft and bone reamings loosely packed into any contained or uncontained defects following the technique of Whiteside (1992). Uncemented pros-theses with long contact bearing stems were then inserted. All 23 cases were able to partially weight bear immediately postoperatively, indicating satisfactory early press fit. No cases of loosening or cases suspicious of loosening have been noted. Of the 23 cases 19 have been followed for at least 1 year. 18/19 showed consolidation of bone defects and in 1 case there was significant bone resorption under the tibial base plate due to stress shielding. Conclusion: This technique is successful in building up moderate bone loss in revision total knee arthroplasty, therefore avoiding the need for excessive bone resection, large metal augments, mass allografts or custom prostheses


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 574 - 574
1 Aug 2008
Aston WJS DeRoeck N Powles DP
Full Access

Aim: To determine whether moderate bone loss in revision total knee arthroplasty can be corrected using an uncemented prosthesis combined with cancellous bone grafting. Methods and Patients: 40 revision total knee replacements were undertaken by the senior author between May 1999 and June 2004. 27 one stage revisions for aseptic loosening and 13 two stage revisions for infection. All cases involved bone loss of grades F1/2 and or T1/2 according to the Anderson Orthopaedic Research Institute Classification (Engh 1998). Bone loss was treated with a mixture of morselized autograft, morselized allograft and bone reamings loosely packed into any contained or uncontained defects following the technique of Whiteside (1992). Uncemented prostheses with long contact bearing stems were then inserted. Patients were followed up prospectively with Oxford and HSS knee scores. Results: All 40 cases were able to partially weight bear immediately postoperatively, indicating satisfactory early press fit. No cases of loosening or cases suspicious of loosening have been noted. Mean follow up of 37 months with no patients requiring re revision, no persistent stem pain and no infection in the one stage revisions. 2 cases of infection in the 2 stage group are discussed, neither have required implant removal. Intraoperative and postoperative complications are discussed as well as range of motion, pain and patient satisfaction. In 39/40 cases bone stock has been restored. In 1 case there was significant bone resorption under the tibial base plate due to stress shielding. Conclusions: This technique is successful in building up moderate bone loss in revision total knee arthroplasty, therefore avoiding the need for excessive bone resection, large metal augments, mass allografts or custom made prostheses


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 334 - 334
1 Sep 2012
Engesaeter L Dale H Hallan G Schrama J Lie S
Full Access

Introduction

Infection after total hip arthroplasty is a severe complication. Controversies still exist as to the use of cemented or uncemented implants in the revision of infected THAs. Based on the data in the Norwegian Arthroplasty Register (NAR) we have studied this topic.

Material and Methods

During the period 2002–2008 45.724 primary THAs were reported to NAR. Out of these 459 were revised due to infection (1,0%). The survival of the revisions with uncemented prostheses were compared to revisions with cemented prostheses with antibiotic loaded cement and to cemented prostheses with plain cement. Only prostheses with the same fixation both in acetabulum and in femur were included in the study. Cox-estimated survival and relative revision risks were calculated with adjustments for differences among groups in gender, type of surgical procedure, type of prosthesis, and age at revision.


The Bone & Joint Journal
Vol. 103-B, Issue 3 | Pages 522 - 529
1 Mar 2021
Nichol T Callaghan J Townsend R Stockley I Hatton PV Le Maitre C Smith TJ Akid R

Aims

The aim of this study was to develop a single-layer hybrid organic-inorganic sol-gel coating that is capable of a controlled antibiotic release for cementless hydroxyapatite (HA)-coated titanium orthopaedic prostheses.

Methods

Coatings containing gentamicin at a concentration of 1.25% weight/volume (wt/vol), similar to that found in commercially available antibiotic-loaded bone cement, were prepared and tested in the laboratory for: kinetics of antibiotic release; activity against planktonic and biofilm bacterial cultures; biocompatibility with cultured mammalian cells; and physical bonding to the material (n = 3 in all tests). The sol-gel coatings and controls were then tested in vivo in a small animal healing model (four materials tested; n = 6 per material), and applied to the surface of commercially pure HA-coated titanium rods.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 74 - 75
1 Jan 2003
Doets HC Olsthoorn PGM Lems WF
Full Access

Introduction

Total hip arthroplasty (THA) is the only successful treatment for patients in whom the hip joint is destroyed by inflammatory arthritis. Due to the effects of both the disease and its treatment elevated rates of complications and of aseptic loosening have been described. Whether with modern uncemented hip prostheses the results can be improved is not fully known. Therefore, we decided to carry out a prospective study.

Material and methods

At the introduction of a new press-fit acetabular component a prospective study on the results of uncemented THA was started. From 1995 to 1999 85 primary THAs were carried out in 72 patients (57 women, 15 men) suffering from inflammatory arthritis. Diagnosis: RA 76, adult-onset Still 4, JIA 3, miscellaneous 2. Mean age at operation was 60 years (SD 15. 9). Clinically, the Harris Hip Score was used for evaluation. Radiographically, the Larsen classification was used and at follow-up radiolucencies and signs of migration were registered.

The implants used in this study were the EPF-PLUS® acetabular component and the SL-PLUS® femoral component (PLUS Endoprothetik AG, Rotkreuz-CH). The EPF-PLUS® acetabular component is a novel modular press-fit cup. Its shell has a triple radius profile on cross-section, thereby creating a gradual lowering of the polar part of the cup. This produces a small gap of about 2 mm. between the acetabulum and the pole of the cup. Therefore, forces are mainly transmitted to the peripheral part of the acetabulum, leading to an enhanced primary stability. Originally, the shell had a gritblasted surface for osseointegration. Since 1996, the outer surface of the cup has been coated with a ground layer of pure titanium and a superficial layer of a crystalline hydroxyapatite (Ti-HA). The gritblasted version was used in 14 hips (1995–1996), the Ti-HA coated version in 71 hips. In 68 hips the cup was implanted by press-fit fixation, in 17 screws were added.

Results

Larsen classification was as follows: 0-1: 6; 3: 17; 4: 60; 5: 2. At follow-up, 5 patients (6 THAs) were deceased. Deep infection required revision in one hip. Another revision was carried out for recurrent dislocations. One grit-blasted cup developed late subsidence and was revised almost 4 years postoperatively. One Ti-HA coated cup failed early due to severe acetabular bone loss. Finally, one femoral component developed a varus tilt and became symptomatic 2 years after implantation, requiring revision. In all 62 patients with 74 THAs in follow-up cup and stem are functioning well, both clinically and radiographically. Harris Hip Score increased from 36. 6 (SD 17. 7) to 87. 9 (SD 11. 8).

Discussion

The medium-term results of the EPF®-PLUS cup show that its primary stability is good and that, as the polar gap rapidly disappears, osseointegration is secure. Only severe acetabular deficiency appears to be a contra-indication for this implant. Also, the SL-PLUS® stem performs well in inflammatory arthritis.


Bone & Joint Research
Vol. 12, Issue 5 | Pages 331 - 338
16 May 2023
Szymski D Walter N Krull P Melsheimer O Grimberg A Alt V Steinbrueck A Rupp M

Aims. The aim of this investigation was to compare risk of infection in both cemented and uncemented hemiarthroplasty (HA) as well as in total hip arthroplasty (THA) following femoral neck fracture. Methods. Data collection was performed using the German Arthroplasty Registry (EPRD). In HA and THA following femoral neck fracture, fixation method was divided into cemented and uncemented prostheses and paired according to age, sex, BMI, and the Elixhauser Comorbidity Index using Mahalanobis distance matching. Results. Overall in 13,612 cases of intracapsular femoral neck fracture, 9,110 (66.9%) HAs and 4,502 (33.1%) THAs were analyzed. Infection rate in HA was significantly reduced in cases with use of antibiotic-loaded cement compared with uncemented fixated prosthesis (p = 0.013). In patients with THA no statistical difference between cemented and uncemented prosthesis was registered, however after one year 2.4% of infections were detected in uncemented and 2.1% in cemented THA. In the subpopulation of HA after one year, 1.9% of infections were registered in cemented and 2.8% in uncemented HA. BMI (p = 0.001) and Elixhauser Comorbidity Index (p < 0.003) were identified as risk factors of periprosthetic joint infection (PJI), while in THA cemented prosthesis also demonstrated an increased risk within the first 30 days (hazard ratio (HR) = 2.73; p = 0.010). Conclusion. The rate of infection after intracapsular femoral neck fracture was statistically significantly reduced in patients treated by antibiotic-loaded cemented HA. Particularly for patients with multiple risk factors for the development of a PJI, the usage of antibiotic-loaded bone cement seems to be a reasonable procedure for prevention of infection. Cite this article: Bone Joint Res 2023;12(5):331–338


The Bone & Joint Journal
Vol. 102-B, Issue 1 | Pages 11 - 16
1 Jan 2020
Parker MJ Cawley S

Aims. Debate continues about whether it is better to use a cemented or uncemented hemiarthroplasty to treat a displaced intracapsular fracture of the hip. The aim of this study was to attempt to resolve this issue for contemporary prostheses. Methods. A total of 400 patients with a displaced intracapsular fracture of the hip were randomized to receive either a cemented polished tapered stem hemiarthroplasty or an uncemented Furlong hydroxyapatite-coated hemiarthroplasty. Follow-up was conducted by a nurse blinded to the implant at set intervals for up to one year from surgery. Results. A total of 115 patients died in the year after surgery. There was a tendency towards a slightly higher mortality in those treated with the uncemented prosthesis after one year (64 vs 51; p = 0.18). For the survivors, there was no significant difference in pain score at any of the time intervals. Patients treated using the cemented hemiarthroplasty recovered mobility better than those treated with the uncemented hemiarthroplasty (mean decrease in mobility score at one year: 1.7 vs 1.1, SD 1.9; p = 0.008). There was a tendency to more periprosthetic fractures in the uncemented group (five vs two cases; p = 0.45), but overall the need for further surgery was similar in both groups (nine vs seven cases). There were four perioperative deaths in the cemented group. Conclusion. These results indicate that a contemporary cemented hemiarthroplasty gives better results than an uncemented hemiarthroplasty for patients with a displaced intracapsular fracture of the hip. When the condition of the patient permits, a cemented hemiarthroplasty should be used. Cite this article: Bone Joint J. 2020;102-B(1):11–16


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_14 | Pages 12 - 12
1 Nov 2021
Cordero-Ampuero J Velasco P
Full Access

To compare complications, survivorship and results in 2 groups of Furlong-HAP Active, one with ceramic-ceramic and the other with metal-XLPE friction pair. Prospective, non-randomized, comparison of 2 series of JRI uncemented prosthesis, implanted with identical protocol by 1 surgeon in 1 hospital from 2006 to 2014. Friction pair was ceramic (Biolox Forte or Delta) in 35 patients of 53.7+/−10.6 years (25–69) (21 males, 60%), and CrCo-XLPE in 65 cases of 69.0+/−8.9 years (42–81) (36 males, 55%); there were significant differences in age (p<0.00001) but not in sex (p=0.6565). Head diameter: Ce-Ce with 19 of 28mm, 9 of 32 and 7 of 36mm; Me-PE with 63 of 28mm, 1 of 32 and 1 of 36. Follow-up averaged 10.5+/−3.1 years (1–15) in ceramic and 9.8+/−3.8 years (2–15) in XLPE group. Pearson, Fisher, Kolmogorov-Smirnov, Student, Mann-Whitney, calculated with the informatic tools Microsoft Excel 2007 and . https://www.socscistatistics.com/tests/. . Complications in ceramic joints: 2 late infections (Fisher exact test=0.6101) (1 DAIR, 1 one-stage exchange); 1 dislocation (Fisher exact test=0.2549) (closed reduction); 1 Vancouver C fracture (ORIF) (Fisher exact test=0.6548). Complications in Me-XLPE joints: 2 late infections (Fisher=0.6101) (1 DAIR, 1 two-stage exchange); 7 dislocations (Fisher=0.2549) (2 early, open reduction) (5 late: 3 closed reduction, 1 cup revision, 1 constrained cup); 4 Vancouver B fractures (Fisher=0.6548) (2 intraoperative, cerclages; 2 late, exchange). Final follow-up: Harris Hip Score averaged 93.2+/−13.7 (23–100) in ceramic and 94.3+/−8.7 (65–100) in XLPE joints (p=0.64552). Wear: 0.06+/−0.38mm (0–1.5) in ceramic and 0.16+/−0.5mm (0–2) in Me-PE THAs (p=0.30302). Osteolysis in Charnley-De Lee zones: 8 zones (6 patients) (17%) in ceramic cups, 25 zones (15 patients) (23%) in XLPE cups (p=0.980127). Survivorship without any surgery or closed reduction after 15 years: 91.0% in ceramic joints, 83.8% in Me-XLPE joints. Survivorship without component exchange after 15 years: 93.9% in ceramic joints, 93.6% in Me-XLPE joints. At least after 10 years follow-up of Furlong-HAP Active, metal-XLPE and ceramic-ceramic joints present no significant differences in complications, clinical score, wear, acetabular osteolysis, or survivorship without component exchange. On the contrary, survivorship without any surgery or closed reduction is different because of the high rate of dislocation in 28mm metal-poly joints


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 443 - 443
1 Sep 2009
Claassen W Nijs J Jaecques S Van der Perre G Mulier M
Full Access

Radiostereometric analysis (RSA) is a technique that can be used to measure in-vivo micro-motion of the components of hip arthroplasty. 86 patients received a titanium custom-made prosthesis. The average age was 64 year (20y –84y). During the study 30 patients out of 86 received a cementless femoral stem. The choice of stem fixation is determined by the quality of the bone. In all cases a 36 mm cobalt chromium head is used. Spherical tantalum markers, chosen because of the proven biocompatibility, were inserted into stable locations in the femoral bone during surgery using a specialized insertion tool, according to the protocol. Evaluation was done 1, 6, 12, 24, 52 weeks after surgery. Overall subsidence follows a parallel pattern for the cemented and uncemented prosthesis that is slightly stronger in for the uncemented prosthesis. Over the 6 months evaluation period the prosthesis migrates towards the lateral side with 0.25 mm in both groups. An anteroversion of 0.5° to 1° is noted at 6 months follow-up. The varus valgus movement of the prosthesis is similar for both groups at 6 months. At 6 weeks a slight valgus flexion is noted, this is reversed at 3 months. At this point in time the effect is more pronounced in the group with a cemented prosthesis. Micro motion is difficult to assess on plain radiography. In this study more subsidence is noted in the uncemented prosthesis compared to the cemented. The degree of rotation of the stem measured in our study is comparable with those reported by others. In our primary THR we observe a bi-modal micromotion except for the subsidence the initial movement up till 6 weeks is reversed at 3 months follow-up and at 6 months the prosthesis seems stabilized, though longer follow-up is required to confirm stabilization


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 1 | Pages 116 - 122
1 Jan 2010
Parker MI Pryor G Gurusamy K

We undertook a prospective randomised controlled trial involving 400 patients with a displaced intracapsular fracture of the hip to determine whether there was any difference in outcome between treatment with a cemented Thompson hemiarthroplasty and an uncemented Austin-Moore prosthesis. The surviving patients were followed up for between two and five years by a nurse blinded to the type of prosthesis used. The mean age of the patients was 83 years (61 to 104) and 308 (77%) were women. The degree of residual pain was less in those treated with a cemented prosthesis (p < 0.0001) three months after surgery. Regaining mobility was better in those treated with a cemented implant (p = 0.005) at six months after operation. No statistically significant difference was found between the two groups with regard to mortality, implant-related complications, re-operations or post-operative medical complications. The use of a cemented Thompson hemiarthroplasty resulted in less pain and less deterioration in mobility than an uncemented Austin-Moore prosthesis with no increase in complications


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 48 - 48
1 Mar 2006
Garcia-Sandoval M Gava R Cervero J Hernandez-Vaquero D
Full Access

Background: Measurement of quality of life (QOL) and functional status provides important additional information for priority setting in health policy formulation and resource allocation. Our aim was to define the differences in the health-related quality of life between hip artroplasties with cementation and without cementation. The last objective was to reunite evidences on the advantages and disadvantages of both systems of hip arthroplasty fixation. Methods: We analyzed a random sample of patients in surgical waiting list of total hip arthroplasty, between 65 and 75 years, divided in two groups of 40 patients who received a cemented or uncemented THA, respectively. We compared the pre-operative characteristics and at a year after operation changes in the Nottingham Health Profile (NHP) and SF-12 self-administered questionnaires. We also performed the specific Harris hip score. To make the different scoring systems comparable, all scores were transformed to a 0-to 100-point scale, with 100 points indicating best health. Differences among these groups were compared using the Mann-Whitney U test. Results: All patients increased their QOL scores. Both groups had similar QOL scores before surgery. At 1 year, patients with the uncemented prosthesis had slightly higher scores for energy, pain, and emotional reaction. Changes in QOL scores were, however, very similar. Conclusions: The use of an uncemented prosthesis does not impair early outcome


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 291 - 291
1 May 2010
Rud-Sørensen C Pedersen A Johnsen S Riis A Overgaard S
Full Access

Introduction: We studied the survival of primary total hip arthroplasty (THA) in patients undergoing surgery because of rheumatoid arthritis (RA) and compared our results to the survival of primary THA in patients undergoing surgery because of osteoarthritis (OA). Furthermore, we evaluated the effect of primary THA-survival in RA-patients concerning multiple confounders such as age, gender, comorbidity, and cemented/uncemented prosthesis. Material and Methods: Using the Danish Hip Arthroplasty Register we gathered info concerning 1.302 primary THA’s in 1.106 RA-patients and 41.848 primary THA’s in 35.729 OA-patients. These patients underwent surgery from 1995 to 2004. Using the Cox regression model we estimated the relative risk (RR) for revision due to aseptic loosening, other reasons, and all reasons and adjusted for above mentioned confounders. Results: The adjusted RR’s for cup-revision of primary THA’s in patients with RA (compared to OA) were 1.22 (aseptic loosening − 95% Confidence Interval (CI) 0.75–1.99), 0.90 (other causes for revision − 95% CI 0.61–1.32), and 1.00 (all revisions − 95% CI 0.74–1.35). For the stem the RR’s were 0.50 (aseptic loosening − 95% CI 0.25–0.99), 0.58 (other causes for revision − 95% CI 0.35–0.95), and 0.54 (all revisions − 95% CI 0.36–0.80). RR for all revisions (both cup and stem) was 0.83 (95% CI 0.64–1.09). The RAsubanalysis showed an increased RR (all revisions) for men compared to women (RR 2.60; 95% CI 1.19–5.66). No significant result concerning all revisions for age, comorbidity, and cemented/ uncemented prosthesis was found. The mean follow-up was 5,4 years for RA and 4,8 years for OA. Conclusion: The survival of primary THA’s in RA could not be associated with any clearly overall increased risk of revision when compared to OA. However, male gender seems to be a risk factor for undergoing revision-THA in the RA-subgroup


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 84 - 84
1 Mar 2006
Winkler H Krems K
Full Access

Aims: Infection of total hip replacement still is considered a devastating complication. One stage revision, meaning removal of implant and debris together with insertion of a new prosthesis during the same operation, reduces rehabilitation time and costs. To overcome the disadvantages of using cement, uncemented techniques seem to be favourable. Methods: After removal of the implants debridement is performed as in conventional septic surgery. After thorough cleaning and rinsing, bone voids are filled with bone graft using an impaction technique. We use cancellous bone that is free from antigenic material but intact structures concerning collagen and mineral content. The bone is impregnated with high loads of antibiotic, using a proprietory incubation technique. There are two options of antibiotic impregnation: vancomycin or tobramycin. The impregnation procedure guarantees high levels of antibiotics at the grafting site for several weeks during which the antibiotic is released into the surrounding. Systemic drug levels usually are undetectable. Consequently an uncemented prosthesis is inserted. Wounds are drained and closed immediately, rehabilitation is performed as after non-septic surgery. Between 1996 and 2003 35 patients have been revised because of culture proven infection of a hip endoprostheses. All hips could be followed with a minimum of 3months and a maximum of 6years. Results: Wound healing was uneventful in all cases. Mean hospital stay was 16days (10–32days). In three hips there was recurrence of the infection, diagnosed between 6 and 12 weeks after surgery. One could be successfully re-operated using the same technique, the other two were converted to a girdlestone situation. All other 32 hips showed no sign of infection until the last follow up. Conclusion: One stage non-cemented revision may provide an excellent solution for infected total hip replacement. However, several principles need to be observed. Bone processed in an adequate way represents an excellent carrier for vancomycin and tobramycin. Using an antibiotic graft compound eradication of pathogens, grafting of defects and re-insertion of an uncemented prosthesis may be accomplished in a one stage procedure. Since the graft gradually is replaced by healthy own bone, improved conditions may be expected even in the case of another revision


Bone & Joint Research
Vol. 13, Issue 10 | Pages 611 - 621
24 Oct 2024
Wan Q Han Q Liu Y Chen H Zhang A Zhao X Wang J

Aims

This study aimed to investigate the optimal sagittal positioning of the uncemented femoral component in total knee arthroplasty to minimize the risk of aseptic loosening and periprosthetic fracture.

Methods

Ten different sagittal placements of the femoral component, ranging from -5 mm (causing anterior notch) to +4 mm (causing anterior gap), were analyzed using finite element analysis. Both gait and squat loading conditions were simulated, and Von Mises stress and interface micromotion were evaluated to assess fracture and loosening risk.


The Bone & Joint Journal
Vol. 106-B, Issue 6 | Pages 540 - 547
1 Jun 2024
Nandra RS Elnahal WA Mayne A Brash L McBryde CW Treacy RBC

Aims

The Birmingham Hip Resurfacing (BHR) was introduced in 1997 to address the needs of young active patients using a historically proven large-diameter metal-on-metal (MoM) bearing. A single designer surgeon’s consecutive series of 130 patients (144 hips) was previously reported at five and ten years, reporting three and ten failures, respectively. The aim of this study was to extend the follow-up of this original cohort at 25 years.

Methods

The study extends the reporting on the first consecutive 144 resurfacing procedures in 130 patients for all indications. All operations were undertaken between August 1997 and May 1998. The mean age at operation was 52.1 years (SD 9.93; 17 to 76), and included 37 female patients (28.5%). Failure was defined as revision of either component for any reason. Kaplan-Meier survival analysis was performed. Routine follow-up with serum metal ion levels, radiographs, and Oxford Hip Scores (OHSs) was undertaken.


The Bone & Joint Journal
Vol. 105-B, Issue 5 | Pages 467 - 470
1 May 2023
McBryde CW Prakash R Haddad FS


The Bone & Joint Journal
Vol. 106-B, Issue 5 Supple B | Pages 59 - 65
1 May 2024
Liu WKT Cheung A Fu H Chan PK Chiu KY

Aims

Isolated acetabular liner exchange with a highly crosslinked polyethylene (HXLPE) component is an option to address polyethylene wear and osteolysis following total hip arthroplasty (THA) in the presence of a well-fixed acetabular shell. The liner can be fixed either with the original locking mechanism or by being cemented within the acetabular component. Whether the method used for fixation of the HXLPE liner has any bearing on the long-term outcomes is still unclear.

Methods

Data were retrieved for all patients who underwent isolated acetabular component liner exchange surgery with a HXLPE component in our institute between August 2000 and January 2015. Patients were classified according to the fixation method used (original locking mechanism (n = 36) or cemented (n = 50)). Survival and revision rates were compared. A total of 86 revisions were performed and the mean duration of follow-up was 13 years.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 134 - 134
1 May 2016
Lapaj L Mroz A Wendland J Markuszewski J
Full Access

Introduction. Titanium nitride (TiN) coatings are used in total hip arthroplasty to reduce friction of bearing couples or to decrease the allergic potential of orthopaedic alloys. Little is known about performance of currently manufactured implants, since only few retrieval studies were performed, furthermore they included a small number of implants manufactured over 15 years ago. Aim of study. To examine wear and degradation of retrieved TiN coated femoral heads articulating with ultra-high molecular weight polyethylene (UHMWPE). Methods. We included eight femoral heads with a made od TiAl6V4 alloy and coated with TiN using Physical Vapour Deposition (PVD). All heads (28 and 32 mm) were retrieved after at least 12 months of use (range 12–56). The reason for revision was aseptic loosening in 6 cases, septic loosening in one case and recurrent dislocations (five episodes) in one uncemented prosthesis. One unused head was included as reference sample. All implants were evaluated with light microscopy, Scanning Electron Microscopy (SEM) with Energy-Dispersive X-ray Spectroscopy (EDS). 30 SEM images from each implant were digitally analysed using ImageJ software to compare damage in loaded and non weight-bearing parts of the heads. Results. Studies with light microscopy revealed severe damage to the dislocated femoral head, with multiple metallic scratches. SEM studies indicated presence of multiple scratches and pinholes with a diameter of 1–10 µm (Fig1a,b,). Residue from the manufacturing process was present in all implants in form of pure Ti droplets found in round voids. In all implants we found irregular areas (diam. 20–50 µm, Fig 1c,d) where the coating was delaminated from the substrate metal with cracks arising from coating defects (Fig1e-h). Some of these debonded fragments were embedded into the PVD layer in weight-bearing parts of all heads. In one head, which was subjected to dislocations we observed deposits of titanium alloy from the acetabular shell (Fig 2a,b). The deposits were accompanied by large patches of delaminated coating as well as multiple cracks (Fig 2c,d). Small fragments of the acetabular titanium alloy damaged the coating in third body mechanism. Surprisingly in three implants we EDS analysis revealed similar spheres (diam. 1–10 µm) containing Niobium (Nb), although this element is not a part of any of the components used in the implants(Fig 2e,f). Interestingly presence of Nb droplets were associated with a higher number of other defect in these heads both in weight-baring and non weight-bearing parts of the heads suggesting inferior coating quality in these cases (Fig 2 g,h; Fig3, cases H2,H5,H8). Conclusions. Compared to previous studies we did not observe severe wear or the coating, however we observed some degradation of the film in vivo. Our results indicate that dislocation can lead to severe failure of the coating in vivo. Moreover presence of Nb residues and coexisting defects in some implants suggests inferior coating quality in these implants and indicates the need for strict monitoring of the production process. This study was funded by a grant from the National Science Centre nr 2012/05/D/NZ5/01840


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_30 | Pages 38 - 38
1 Aug 2013
Baird E Spence S Ayana G
Full Access

Displaced fractures of the neck of femur are routinely treated in the elderly by either cemented hemiarthoplasty, in the fit, or uncemented hemiarthroplasty, in the less fit. In Scotland the Scottish Intercollegiate Guidelines Network (SIGN) guidelines are followed to identify which patients should have a cemented prosthesis. This is based on cardiovascular status, and the age and fragility of the patient. An uncemented prosthesis should be a final operation. A peri-prosthetic fracture is considered a failure of treatment as the patient then has to undergo an operation with a far greater surgical insult. We looked at all neck of femur fractures over a period of Jan 2007 to June 2010. The number of the peri-prosthetic fractures for uncemented hip hemiarthroplasties was established, and a case note review was carried out. There was 1397 neck of femur fractures. 546 hemiarthroplasties were carried out, of which 183 were cemented, and 363 uncemented. 15 patients (4% of uncemented hemiarthoplasties) had peri-prosthetic fractures. There were no peri-prosthetic fractures in the cemented group, p = 0.004 using Fisher's exact test. The case notes of these patients were analysed. We found there was a common link of significant cardiovascular risk, lack of falls assessment (only 14% of the patients had a completed falls assessment and 21% sustained their fracture during an admission to hospital) and confusion (50% had a degree of dementia that caused significant confusion). Cemented implants should be considered in all patients, especially those who are cognitively impaired or have failed falls assessments; even if the cardiovascular risk is significant. This decision should be made in conjunction with a senior anaesthetist. This is being implemented in our unit and a prospective audit is being carried out over the same time period (July 2010 to Dec 2013) to assess the benefit


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 30 - 30
1 Sep 2012
Al-Atassi T Chou D Boulton C Moran C
Full Access

Introduction. Cemented hemiarthroplasty for neck of femur fractures has been advocated over uncemented hemiarthroplasty due to better post-operative recovery and patient satisfaction. However, studies have shown adverse effects of bone cement on the cardio-respiratory system which may lead to higher morbidity and mortality. Therefore, in some institutes, the use of an uncemented prosthesis has been adopted for patients with a high number of co-morbidities. The aim was to compare early mortality rates for cemented vs. uncemented hemiarthroplasties. Method. Cohort study of displaced intracapsular hip fractures treated with hemiarthroplasty between 1999–2009 at one institute. A total of 3094 hemiarthroplasties performed; out of which 1002(32.4%) were cemented and 2092(67.6%) were uncemented. 48hour and 30day mortality rates for the two groups were compared and a multivariate Cox regression model used to eliminate confounding factors. Significant confounding factor included age, sex, mini mental test score, medical co-morbidities, Nottingham Hip Fracture Score and delay to surgery. Results. The study showed that, after eliminating confounding factors, 48hour mortality in the cemented group was 0.3% compared to 0.5% in the uncemented group (p=0.388). However, the adjusted 30day mortality rate for the cemented group (4%) was shown to be significantly lower than for the uncemented group (10.8%) (p< 0.001). Conclusion. The use of cement in hip hemiarthroplasty is not associated with an increased rate of mortality at 48hours or at 30days. Along with emerging evidence of better post-op recovery and patient satisfaction with the use of a cemented prosthesis, we support the use of cement for all patients undergoing hip hemiarthroplasty