Abstract

Tibial shaft fractures require surgical stabilization preferably by intramedullary nailing. However, patients often report functional limitations even years after the injury. This study investigates the influence of the surgical approach (transpatellar vs. parapatellar) on gait performance and patient reported outcome six months after surgery.

Twenty-two patients with tibial shaft fractures treated by intramedullary nailing through a transpatellar approach (TP: n=15, age 41±15, BMI 24±3) or a parapatellar approach (PP: n=7, age 34±15, BMI 23±2) and healthy, matched controls (n=22, age 39±13, BMI 24±2) were assessed by instrumented motion analysis six months after intramedullary nailing. Short musculoskeletal function assessment questionnaire (SMFA) as well as kinematic and kinetic gait data were collected during level walking. Comparisons among approach methods and control group were performed by analysis of variance and Mann-Whitney test.

Six months after surgery, knee kinetics in both groups differed significantly compared to controls (p <.04). The approach method affected gait speed (TP: p = .002; PP: p = .08) and knee kinematics in the early stance phase (TP: p = .011; PP: p = .082), with the parapatellar approach showing a more favorable outcome. However, the difference between patient groups was not significant for any of the assessed gait parameters (p > .2). Also, no differences could be found in the bother index (BI) or function index (FI) of SMFA between surgical approach methods (BI: TP: Mdn = 7.2, PP: Mdn = 9.4; FI: TP: Mdn = 10.3, PP: Mdn = 9.2, p > .7).

Our study demonstrates, that six months after surgery for tibial shaft fractures functional limitations remain. These limitations appear not to be different for either a trans- or a parapatellar approach for the insertion of the intramedullary nail. The findings of this study are limited by the relatively short follow up time period and small number of patients. Future studies should investigate the source of the functional limitation after intramedullary nailing of tibial shaft fractures.

Malalignment is a common complication following tibial surgery, occurring in 10% of fractures. This is associated with prolonged healing time and non-union. It occurs due to inability to maintain a satisfactory reduction. A reduction device, such as the Staffordshire Orthopaedic Reduction Machine (STORM), permits the surgeon to manipulate the fracture and hold it reduced.

A retrospective parallel case series was undertaken of all patients undergoing tibial nails over a six-year period from 2014 to 2021. Patient demographics were obtained from medical records. Operative times obtained from the theatre IT system and included the time patient entered theatre and surgical start and finish times for each case.

Anteroposterior and lateral long leg post-operative radiographs were reviewed. Angulation was measured in both coronal and sagittal planes, by two separate orthopaedic surgeons. A reduction was classified to be ‘mal-aligned’ if the angle measured was greater than 5 degrees. One tailed unpaired t-test was used to compare alignment in each plane. Bony union was assessed on subsequent radiographs and was determined according to the Radiographic Union Score for Tibial Fractures

31 patients underwent tibial nail during the time period. 8 patients were lost to follow up and were excluded. Of the remaining 23 patients, the STORM device was utilised in 11.

The overall mean alignment was acceptable across all groups at 2.17° in the coronal plane and 2.56° in the saggital plane. Analysing each group individually demonstrated an improved alignment when STORM was utilised: 1.7° (1°–3°) vs 2.54° (0°–5°) for the coronal plane and 1.6° (0°–3°) vs 3.31° (0°–9°) in the saggital plane. This difference was significant in saggital alignment (p=0.03) and showed a positive trend in coronal alignment, although was not significant (p=0.08)

The time in theatre was shorter in the control group with a mean of 113 minutes (65 to 219) in comparison to STORM with a mean of 140 minutes (105 to 180), an increased theatre time of 27 minutes (p=0.04).

This study demonstrates that STORM can be used in the surgical treatment of tibial fractures resulting in improved fracture alignment with a modest increase in theatre time.

Aims: Our objectives is to evaluate the functional outcome of tibial nailing in 29 patients operated at the South Birmingham Trauma unit in the period between 1992–1996. Methods: This is a retrospective study; all patients included had a tibial nail inserted for two or more years. Assessment was made by reviewing the notes, interviewing and examining the patients. A pro-forma was for each patient was collected covering various activities and outcomes. Results: The results showed that the majority of patients demonstrated a compromised activity level, both in their leisure activity and occupation. No statistical difference was observed between reamed and unreamed nails in their functional outcome measurements. Conclusions: Our conclusion that the functional outcome of tibial nailing is not as good as the anatomical restoration would predicts.

The aim of our study was to compare the incidence of post-operative anterior knee discomfort after anterograde tibial nailing by suprapatellar and infrapatellar approaches.

95 subjects presenting with a tibial fracture requiring an intramedullary nail were randomised to treatment using a suprapatellar (SP) or infrapatellar (IP) approach. Anterior knee discomfort was assessed at 4 months, 6 months and 1 year post operatively using the Aberdeen Weightbearing Test-Knee (AWT-K), knee specific patient reported outcome measures and the VAS pain score. The AWT-K is an objective measure which uses weight transmitted through the knee when kneeling as a surrogate for anterior knee discomfort.

53 patients were randomised to an SP approach and 42 to an IP approach. AWT-K results showed a greater mean proportion of weight transmitted through the injured leg compared to the uninjured leg when kneeling in the SP group compared to the IP group at all time points at all follow-up visits. This reached significance at 4 months for all time points except 30 seconds. It also reached significance at 6 months at 0 seconds and 1 year at 60 seconds.

We conclude that the SP approach for anterograde tibial nailing reduces anterior knee discomfort post operatively compared to the IP approach.

Closed intramedullary nailing of the tibia is a well accepted method of treating tibial fractures. There are advantages to perfoming surgery via smaller incisions. These advantages include less muscle dissection, less pain, less blood loss and quicker recovery and discharge from hospital and improved cosmesis.

We have used an existing tibial nail (Zimmer M/DN) to carry out percutaneous nailing of tibial shaft fractures using a modified surgical technique. This report describes the operative technique and our early results.

We have used this technique in 10 patients. The main difference in the technique is the use of a Steinman pin under fluoroscopy to identify the entry point. The average incision length in these patients has been 2.5cm. We have had no early or medium term complications. Length and rotation was restored in all cases. There was no increase in the surgical time or fluoroscopy time for the operation. Post-operative analgesic use was significantly less in these patients when compared with the standard technique. The average length of hospital stay has been reduced by 25% in this early cohort.

Aim: Vascular complications associated with locked intramedullary tibial nailing are rare but always serious. The purpose of this cadaveric study is to define the risk of vascular complications after proximal locking in intramedullary tibial nailing.

Material and Methods: Seven fresh cadaver legs were obtained from the University Hospital of loannina. The Grosse & Kempf Tibial Locking Nail was used with anterior-posterior locking. Each procedure was performed according to a standard protocol. The insertion point of the tibial nail was just above the level of the tibial tuberosity. The direction of the proximal locking screw was oblique from caudal to cranial and from lateral to medial. For imaging, both the nail and screws were removed and titanium screws were inserted, thereby allowing good visualization.

Results: MRI sections combined with CT and 3D-CT have been used to illustrate the findings, as they clearly demonstrate the relationships between the locking screws and adjacent vascular structures. Analysis of these findings highlighted the surgical risks associated with this type of proximal locking and its direction.

Conclusions: Proximal anterior-posterior locking in intramedullary tibial nailing is a hazardous procedure because of the small distance between tibia and vascular structures. The use of a new direction for proximal anterior-posterior locking is recommended.

Purpose: Vascular complications associated with locked intramedullary tibial nailing are rare but always serious. The purpose of this cadaveric study is to deþne the risk of vascular complications after proximal locking in intramedullary tibial nailing. Methods: Seven fresh cadaver legs were obtained from the University Hospital of Ioannina. The Grosse & Kempf Tibial Locking Nail was used with anterior-posterior locking. Each procedure was performed according to a standard protocol. The insertion point of the tibial nail was just above the level of the tibial tuberosity. The direction of the proximal locking screw was oblique from caudal to cranial and from lateral to medial. For imaging, both the nail and screws were removed and titanium screws were inserted, thereby allowing good visualization. Results: MRI sections combined with CT and 3D-CT have been used to illustrate the þndings, as they clearly demonstrate the relationships between the locking screws and adjacent vascular structures. Analysis of these þndings highlighted the surgical risks associated with this type of proximal locking and its direction. Conclusions: Proximal anteriorposterior locking in intramedullary tibial nailing is a hazardous procedure because of the small distance between tibia and vascular structures. The use of a new direction for proximal anterior-posterior locking is recommended as an alternative procedure to eliminate the potential for iatrogenic lesions.

Purpose of study: To study the effect of an additional locking screw on fracture strain and stability in tibias undergoing intramedullary nailing.

Methods: An additional locking hole was drilled into four tibial nails, 185 mm from the proximal end of the 8 mm x 315 mm solid tibial nails. The nails were locked proximally and distally into a triple strain-gauged sawbone. An osteotomy was created distal to the additional hole, and the construct loaded axially, in flexion and extension, and in torsion with and without the extra locking screw. With the additional locking screw in place, strain increased at the proximal strain gauge site during loading in neutral by 17% (139 mϵ, 91–198) (p=0.01) and flexion by 8% (65 mϵ, 60–73) (p< 0.005). Strain decreased on loading in extension by 10% (141 mϵ, 62–243) (p=0.0497). The extra locking screw decreased strain at the gauge closest to the osteotomy site in all loading positions. Strain showed an overall increase with axial loading of 14% (47 mϵ, 4–105) (p=0.16), an increase with loading in flexion of 2% (9 mϵ, −38 to 62) (p=0.75) but a decrease of 47% (254 mϵ, 6–549) (p=0.18) with loading in extension. A significant reduction in angular motion at the osteotomy site occurred with the addition of the extra locking screw (21° at 34.5 Nm without the screw, 13° at 34.5 Nm with the screw, p=0.001). Additional hole in the shaft of the nail lead to increase the stress from 29 – 48 mPa (29 – 48 N/mm2) but did not fail when vertically loaded with 450 Newtons applied at rate of 5Hz sinusoidal waves for 2 million cycles.

Conclusion: Nails with additional locking options, by altering strain and motion at the fracture site, may have the clinical potential to affect fracture healing with relatively low risk of implant failure.

Introduction: We sought to determine the 1 year patient based outcomes and return to activities for patients with tibia fractures in a randomized trial of reamed and unreamed nail insertion.

Methods: 1226 patients with 830 closed and 392 open tibial shaft fractures were enrolled in a randomized trial comparing reamed with unreamed tibial nail insertion and completed one year follow-up. The average age was 39±16 and 74% were male. Patient based outcomes were determined using the validated SF-36 PCS, the SMFA, and a published return to activity questionnaire. Statistical analysis was performed as a stratified analysis comparing the groups with p < 0.05 designated as significant.

Results: There was no difference in any outcome parameter for any time frame between the reamed and unreamed groups. The 1 year SF36 PCS (a 100 point scale with a mean of 50 in the general population, higher better) was 42.9±11 for the reamed group and 43.5±11 for unreamed group as compared with 52.5±9 for the reamed group and 53.1±9 for the unreamed group pre-injury. The 1 year SMFA (100 point scale, higher is worse) was 18±17 for the reamed group and 17.5±17 for the unreamed group as compared with 7.9±13 for the reamed group and 7.7±13 unreamed group pre-injury.

Conclusion: In patients with tibial shaft fractures treated with intramedullary nails, patient based outcomes are not related to reamed or unreamed insertion. Patients do not return to their preinjury status based on validated outcomes assessments or return to activity by one year after injury.

Purpose: Tibial shaft fractures are a common injury. Tibial nailing is the current standard of care for these injuries, yet there is little information regarding patient based outcomes after nailing. We sought to determine the 1 year patient based outcomes and return to activities for patients with tibia fractures in a randomized trial of reamed and unreamed nail insertion.

Method: Over a 5 year period 1226 patients with 842 closed and 406 open tibial shaft fractures were enrolled in a randomized trial comparing reamed with unreamed tibial nail insertion in 29 trauma centers and had one year follow-up. The average age was 39±16 years and 74% were male. Patient based outcomes were determined using the validated Short Form-36 (SF-36) Physical Component Summary, the Short Musculoskeletal Functional Assessment (SMFA) Dysfunction Index, and a published return to activity questionnaire. Questionnaires were administered during the initial hospitalization to obtain pre-injury status, and then the same outcome instruments were used at the 2 week, 3 month, 6 month, and one year follow-up. Statistical analysis was performed comparing the groups with p < 0.05 designated as significant.

Results: There was no difference in any outcome parameter for any time frame between the reamed and unreamed groups. The 1 year SF-36 PCS (a 100 point scale with a mean of 50 in the general population, higher better) was 42.9±11 for the reamed group and 43.5±11 for unreamed group as compared with 52.5±9 for the reamed group and 53.1±9 for the unreamed group pre-injury. The SMFA Dysfunction Index (100 point scale, higher is worse) at 1 year was 18.2±17 for the reamed group and 17.5±17 for the unreamed group as compared with 7.9±13 for the reamed group and 7.7±13 unreamed group pre-injury.

Conclusion: In patients with tibial shaft fractures treated with intramedullary nails, patient based outcomes are not related to reamed or unreamed insertion. Patients sustaining tibial shaft injuries do not return to their pre-injury status based on validated outcomes assessments or return to activity by one year after injury.

Aims

The study objective was to prospectively assess clinical outcomes for a pilot cohort of tibial shaft fractures treated with a new tibial nailing system that produces controlled axial interfragmentary micromotion. The hypothesis was that axial micromotion enhances fracture healing compared to static interlocking.

Reducing exposure to radiation is a concern to physicians and supporting staff. Little is known about the factors leading to increased exposure in intramedullary nailing of long bone fractures. This study examines antegrade and retrograde nailing of femur and tibia fractures. Factors that increased radiation exposure were obesity, severely comminuted fractures, nails inserted through the piriformis fossa, and insertion of more locking bolts in femoral nails. In addition, femoral nails required more radiation exposure than tibial nails.

Exposure to radiation is a concern to physicians. The purpose of this study was to determine factors associated with increased radiation exposure with intramedullary nailing of long bone fractures.

Femoral nailing through the piriformis fossa, highly comminuted fractures, insertion of more locking bolts (femur), and obesity are each associated with the higher radiation exposure.

Factors associated with increased radiation exposure are identified for tibial and femoral nailing.

Radiation exposure was higher for nailing of femur fractures (ninety-two seconds) compared to nailing of tibia fractures (sixty seconds). Exposure was greatest for insertion through the piriformis fossa (one hundred and twenty-one seconds) and least for retrograde insertion (seventy-four seconds) and intermediate for insertion through the trochanter (eighty-seven seconds). Obese patients (BMI > 30) had higher exposure times for both femoral (obese-one hundred and sixty seconds, non-obese-eighty-five seconds) and tibial nailing (obese-seventy-nine seconds, non-obese-fifty-five seconds). Only the most severely comminuted fracture patterns (Winquist IV) were associated with increased fluoroscopy time. Increasing number of interlocking bolts was associated with higher exposure for the femur but not the tibia.

One hundred and thirty-nine consecutive patients treated with intramedullary nailing for either a femoral shaft (OTA 32, n=71) or tibial shaft (OTA 42, n=68) fracture were prospectively evaluated in this IRB approved study. Radiation exposure (c-arm fluoroscopy time) was measured. Femur fractures were treated with either a retrograde nail (n=24), an antegrade nail inserted through the piriformis fossa (n=20), or an antegrade nail inserted through the tip of the greater trochanter (n=27).

Funding: Smith & Nephew

Intramedullary nailing of tibial fractures is commonplace and freehand techniques are increasingly popular. The standard freehand method has the knee of the injured leg flexed over a radio-lucent bolster. This requires the imaging C-arm to swing from antero-posterior to lateral position several times. Furthermore, guide wire placement; reaming and nail insertion are all performed well above most surgeons' shoulder height. If instead the leg is hung over the edge of the table, the assistant must crouch and hold the leg until the nail is passed beyond the fracture.

We describe a method of nailing which is easier both for the surgeons and the (often inexperienced) radiographer and present a series of 87 consecutive cases managed with this technique.

In our cadaver study plating the fibula in addition to nailing the tibia decreased the mean rotation across the tibial osteotomy site compared to nailing the tibia alone. Although this is statistically significant (p=0.0034) it may not be clinically relevant as the mean values for ROM were 19.10 and 17.96 degrees respectively. Plating the fibula resulted in no statistically significant difference in the mean vertical displacement, angulation or neutral zone.

Therefore, we may conclude that plating the fibula in a combined distal third tibia and fibula fracture does not enhance the stability of tibial IM nailing.

The purpose of this study was to determine if combined distal third tibia and fibula fractures are more stable when fibular fixation is added to the standard tibial IM rodding.

In combined distal third tibia and fibula fractures, plating the fibula does not enhance stability of intramedullary tibial nailing.

No additional incision or soft tissue stripping is required for plating of the fractured fibula.

The average range of motion in rotation was 19.1° for tibial and fibular fixation combined, and 18.0 ° for tibial fixation alone with a difference of 1.1°, which was clinically significant ( p=0.0034). The mean differences in vertical displacement, angulation, and neutral zone were not statistically significant.

Five matched pairs of embalmed cadaveric lower limbs were dissected and stripped of soft tissue. Each tibia received a 9mm solid titanium nail that was locked proximally and distally. Fibular fixation consisted of a seven- hole LCDCP. A 1.5 cm section of tibia and a 1.0 cm section of fibula were removed. Testing was accomplished with an MTS machine. Vertical displacement was tested with an axial load to 500 N, rotation was tested with an internal and external torque of 5 Nm, and angulation was calculated from the vertical displacement data. All displacement data was measured across the osteotomy site.

The mean range of motion in rotation was the only statistically significant finding. However, considering the average range of motion with and without fibular plating of 17.96° and 19.10° respectively, this finding is likely not clinically relevant.

Funding: Tibial nails, bolts, fibular plates and screws provided by Synthes (Paoli, PA, USA)

Introduction: The present study was performed to compare the mechanical properties and fixation stability of tibial nails of the newest generation used in the management of distal metaphyseal fractures. Furthermore, we tried to evaluate whether distal locking with 4 locking screws might increase load-sharing after stabilization of distal metaphyseal tibial fractures. Methods: We used 16 Sawbones third generation large left tibiae (Sawbones Inc., Sweden) to create an unstable distal metaphyseal fracture model (AO type 43-A3). In 8 specimens the fracture was stabilized with 2 nails with 3 distal locking options (4x VersaNail™, DePuy Orthopaedics, Johnson& Johnson, Warsaw, IN; 4x T2 Tibial Nailing System™, Stryker, Kiel, Germany) and in 8 specimens with 2 nails with 4 locking options (4x Connex™, ITS Spectromed, Lassnitzhöhe, Austria; 4x Expert Tibial Nail™, Synthes, Switzerland). Each specimen was loaded cyclically with three loading sequences over a period of 40,000 cycles in each series (700N, 1,500N, 1,800N). Implant stiffnes during axial cyclic loading series in 7° valgus alignement was recorded as well as cycles until failure of the bone-implant-construct. Results: In the second loading series, implant failure was observed in all tibial nails with 3 distal locking screws after a mean period of 57,196.7 cycles. If distal locking was performed with 4 screws, implant failure was recorded in the third and last loading series after a mean period of 87,518.3 cycles (p< 0.001). If distal locking was performed with 3 distal locking screws, implant stiffness was 1776 (±99) N/mm. If distal locking was performed with 4 locking screws, implant stiffness was 2674 (±208) N/mm (p< 0.001). Conclusion: Distal locking with 4 screws improves implant-bone stability. Stability is influenced by the number of locking screws and not by screw diameter. In these fracture type, nails with 4 distal locking options should be used