Aims. We present a case series of five patients who had revision surgery following magnetic controlled growing rods (MGCR) for early onset scoliosis. Metallosis was found during revision in four out of five patients and we postulated a mechanism for rod failure based on retrieval analysis. Patients and Methods. Retrieval analysis was performed on the seven explanted rods. The mean duration of MCGR from implantation to revision was 35 months (17 to 46). The mean age at revision was 12 years (7 to 15; four boys, one girl). Results. A total of six out of seven rods had tissue metallosis and pseudo-capsule surrounding the actuator. A total of four out of seven rods were pistoning. There were two rods which were broken. All rods had abrasive circumferential markings. A significant amount of metal debris was found when the actuators were carefully cut open. Analytical electron microscopy demonstrated metal fragments of predominantly titanium with a mean particle size of 3.36 microns (1.31 to 6.61). Conclusion. This study highlights concerns with tissue metallosis in MCGR. We recommend careful follow-up of patients who have received this implant. Cite this article: Bone Joint J 2016;98-B:1662–7

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CRP is an acute-phase protein that is used as a biomarker to follow severity and progression in infectious and inflammatory diseases. Its pathophysiological mechanisms of action are still poorly defined. CRP in its pentameric form exhibits weak anti-inflammatory activity. The monomeric isoform (mCRP) exerts potent proinflammatory properties in chondrocytes, endothelial cells, and leucocytes. No data exist regarding mCRP effects in human intervertebral disc (IVD) cells. This work aimed to verify the pathophysiological relevance of mCRP in the aetiology and/or progression of IVD degeneration.

Introduction. Morphological parameters are used to describe curve characters in AIS like curve location, curve magnitude, stiffness etc. Like all other morphological metrics the accuracy is more when digital imaging, archiving and extraction of features is used rather than manual measurements. The content Based Image Retrieval system is anew software that allows rapid, accurate documentation of AIS images and their retrieval by visual content. Classification systems and their shortcomings. Traditional classifications only looked at curve location (Ponsetti/Friedman); this was enhanced to add curve flexibility (to include or exclude secondary curves in fusion) (PUMC, King/Moe etc). Newer classifications like the Lenke have added sagittal profile into the decision making equation. From 5 basic curve types the subtypes have increased to 42 potential curve patterns by the addition of one parameter!! In future as we understand the 3-D geometry of these curves better we may want to add more measureable items (like degree of rotation) and by adding one term the subtypes would be 128!!! This suggests that we need to have a simple easy to remember way of classifying or eliminate classifications altogether. Experimental evidence. Several experiments were conducted with the new CBIR software which showed that similar images of scoliosis cases could be retrieved without resorting to a classification scheme. Even surgical planning can be made by downloading all similar cases operated before. The variability can be set to any level of precision desired. Significance. In future we may eliminate classifications to decide on curve types and for surgical planning and recall from a large multicentre database similar curves and their surgical plan

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To evaluate the histopathological examination of peri-implant tissue samples as a technique in the diagnosis of postoperative spinal implant infection (PSII).

Introduction. It is becoming increasingly more accepted that Patient Reported Outcome Measures (PROMs) should be used to assess surgical interventions. We report on a pilot study of a generic database with complete pre and post-operative data sets in a UK hospital. Method. 19 cases undergoing lumbar surgery in our institution were prospectively reviewed between January and August 2010. Pre and post–operative data assessing pain, back pain specific function, generic health, work disability and patient satisfaction were collected using a core outcome measures index, EuroQol EQ-5D and Oswestry Disability Index (ODI). Details of surgery and assessment of treatment outcome by the operating surgeon was also assessed. Results. There were 11 males and 8 females. 8 cases were coded as disc herniation, and 11 as spinal stenosis. Levels involved included L3/4 (4), L4/5 (8) and L5/S1 (6). ASA status was 1 (4/19), 2 (12/19) and 3 (3/19). The median operation time for all operations was between 1-2 hours and blood loss was under 500ml for all cases. Complications recorded were one dural tear and one wound infection. Post operatively the COMI score improved from 8.7 to 7 overall (p=0.028) and the leg pain score improved from 8 to 7 overall (p=0.009). The EQ-5D improved from 0.09 to 0.36. The ODI improved from 60 to 40 (p=0.03). Patients reported being satisfied in 73% of cases and the surgeon reported a good or excellent result in 65% of cases. Conclusion. The Spine Tango is an effective and user friendly tool for data collection. Data entry and extraction is easy. It is security enhanced and no Patient identifiable data (PID) is transferred outside the host institution. Data retrieval can be done online with clear-cut graphs and data tables or by downloading data and importing into a statistical package for more complex, analyses

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Magnetically controlled growing rods (MCGR) have been gaining popularity in the management of early-onset scoliosis (EOS) over the past decade. We present our experience with the first 44 MCGR consecutive cases treated at our institution.

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The purpose of this study was to investigate the risk of additional surgery in the lumbar spine and to describe long-term changes in patient-reported outcomes after surgery for lumbar disc herniation in adolescents and young adults.

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Chronic low back pain due to degenerative disc disease is sometimes treated with fusion. We compared the outcome of three different fusion techniques in the Swedish Spine Register: noninstrumented posterolateral fusion (PLF), instrumented posterolateral fusion (IPLF), and interbody fusion (IBF).

We validated the North American Spine Society (NASS) outcome-assessment instrument for the lumbar spine in a computerised touch-screen format and assessed patients’ acceptance, taking into account previous computer experience, age and gender.

Fifty consecutive patients with symptomatic and radiologically-proven degenerative disease of the lumbar spine completed both the hard copy (paper) and the computerised versions of the NASS questionnaire. Statistical analysis showed high agreement between the paper and the touch-screen computer format for both subscales (intraclass correlation coefficient 0.94, 95% confidence interval (0.90 to 0.97)) independent of computer experience, age and gender. In total, 55% of patients stated that the computer format was easier to use and 66% preferred it to the paper version (p < 0.0001 among subjects expressing a preference). Our data indicate that the touch-screen format is comparable to the paper form. It may improve follow-up in clinical practice and research by meeting patients’ preferences and minimising administrative work.