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Bone & Joint Research
Vol. 12, Issue 1 | Pages 58 - 71
17 Jan 2023
Dagneaux L Limberg AK Owen AR Bettencourt JW Dudakovic A Bayram B Gades NM Sanchez-Sotelo J Berry DJ van Wijnen A Morrey ME Abdel MP

Aims

As has been shown in larger animal models, knee immobilization can lead to arthrofibrotic phenotypes. Our study included 168 C57BL/6J female mice, with 24 serving as controls, and 144 undergoing a knee procedure to induce a contracture without osteoarthritis (OA).

Methods

Experimental knees were immobilized for either four weeks (72 mice) or eight weeks (72 mice), followed by a remobilization period of zero weeks (24 mice), two weeks (24 mice), or four weeks (24 mice) after suture removal. Half of the experimental knees also received an intra-articular injury. Biomechanical data were collected to measure passive extension angle (PEA). Histological data measuring area and thickness of posterior and anterior knee capsules were collected from knee sections.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 78 - 78
1 Jul 2012
Talawadekar G Rose B Elnikety S Grigoras I Jeer P
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Introduction. As intra-operative fluoroscopic identification of the isometric MPFL attachment to the femur can be imprecise and laborious in a surgical setting, we used clinical criteria to identify the isometric point and then studied post-operative radiographs to find out whether it was achieved and compared it with functional outcome. Materials and Methods. Sixteen patients underwent 17 MPFL reconstructions using autologous semi-tendinosis tendon graft. Clinical judgement was used to identify the optimal point for femoral attachment of the MPFL without fluoroscopy control. Post-operative radiographs at 2 weeks were analysed to confirm whether an isometric point for the reconstructed MPFL was achieved by dividing the distal femur into 4 quadrants by 2 lines on the lateral radiograph. Telephonic interview was conducted to assess functional scores using the Kujala score at a mean follow-up of 13 months. Results. In only 4 of the 17 cases, the femoral point of attachment lay in the radiographically isometric (antero-proximal) quadrant. In 8 of 17 knees, the point of MPFL attachment lay in the antero-distal quadrant. However, there was an improvement in the functional score in 14 of 16 patients, with none reporting recurrence of patellar instability. The position of the reconstructed MPFL did not correlate with functional score. Conclusion. Over-reliance on a clinical method alone for identification of the optimal point for MPFL attachment without an intra-operative radiograph leads to radiographically non-isometric positioning in a majority of cases. In the clinical setting, however, this does not correlate with adverse functional outcome, although intra-operative fluoroscopy may improve the anatomical isometry, and we therefore suggest the use of a qualitative clinical method to achieve optimal