Purpose: Malignant primary tumours of the spine require wide resection with preservation of the cord and radicular elements. The purpose of this work was to report our oncological results and complications after spinal surgery for this indication. Material and methods: Twenty-two patients, mean age 30 years (15–65) underwent surgery. The pathology diagnosis was made preoperatively. There were 16 high-grade tumours, Ewing (n=7), osteosarcoma (n=5), other (n=4), and six low-grade tumours, chondrosarcoma (n=5), osteosarcoma (n=1). Four patients experienced local recurrence after an insufficient initial resection and three required emergency laminectomy. Sagittal hemivertebrectomy was performed in 11 patients for pediculotransverse tumours and total vertebrectomy in 10 patients for corporeal tumours. Posterior fixation was not used in one patient (Ewing tumour) in order to preserve the Adamkiewitz artery. Results: Complete oncological resection was achieved in 14 patients. The surgical margins were in a malignant zone in 7. At mean 6-year follow-up, ten patients were surviving disease-free (4 Ewing, 4 osteosarcoma, 2 chondrosarcoma), and one was living with active disease (chondrosarcoma). Eleven patients died: metastasis (n=4), local recurrence (n=6), infarction 3 months after surgery (n=1). Among the seven patients with local recurrence,osteosarcoma (n=5),chondrosarcoma (n=2), three had local recurrence at initial management and only one was living at last follow-up (active chondrosarcoma). There were no neurological complications; there were four mechanical complications (nonunion) after total vertebrectomy which required four re-operations. Discussion: Survival rate in this series was 45% at six years, comparable with rates reported in the literature (40 – 50% at 5 years). Local recurrence was observed in 85% of patients whose surgical margins were in malignant tissue (67–100% in the literature). Among the four patients who had recurrent disease at the time of surgery, complete resection was possible in only one. This patient is living (Ewing sarcoma responding to adjuvant therapy). Incomplete surgery or a poor biopsy procedure aggravates the prognosis. Mechanical failure is observed after total vertebrectomy if anterior osteosynthesis is not associated with the posterior fixation. Conclusion: Wide surgical resection of
Chondrosarcoma is the second most common surgically treated
Aims. Socioeconomic and racial disparities have been recognized as impacting the care of patients with cancer, however there are a lack of data examining the impact of these disparities on patients with bone sarcoma. The purpose of this study was to examine socioeconomic and racial disparities that impact the oncological outcomes of patients with bone sarcoma. Methods. We reviewed 4,739 patients diagnosed with
Aims. The primary aim of this study was to determine the effect of
the duration of symptoms (DOS) prior to diagnosis on the overall
survival in patients with a
Background: And Aims Pathological fractures of the proximal femur due to
Ewing Sarcoma is the second most common
INTRODUCTION. Allograft reconstruction after resection of
The purpose of this study is to investigate the causes and characteristics of the aggressive solitary bone lesion in patients over the age of forty. Over a four year period, 318 patients over the age of forty were referred to our institution with what we would define as an aggressive solitary bone lesion. Further investigation and diagnostic biopsy as appropriate were performed in all patients. The lesions were then defined according to their radiological appearance, pathology and site. The nature of these lesions was then subdivided into several broad groups. A diagnosis of
Our centre has used a specially designed custom-made endoprostheses with curved stems to reconstruct femoral defects in patients with residual short proximal femur after excision of
Patients who have limb amputation for musculoskeletal
tumours are a rare group of cancer survivors. This was a prospective
cross-sectional survey of patients from five specialist centres
for sarcoma surgery in England. Physical function, pain and quality
of life (QOL) outcomes were collected after lower extremity amputation
for bone or soft-tissue tumours to evaluate the survivorship experience
and inform service provision. Of 250 patients, 105 (42%) responded between September 2012 and
June 2013. From these, completed questionnaires were received from
100 patients with a mean age of 53.6 years (19 to 91). In total
60 (62%) were male and 37 (38%) were female (three not specified).
The diagnosis was
The proximal humerus is the third most common site for
We aimed to identify the incidence, outcome and prognostic factors associated with spindle cell sarcomas of bone (SCSB). We studied 196 patients with a primary non-metastatic tumour treated with the intent to cure. The results were compared with those of osteosarcoma patients treated at our hospital during the same period. The overall incidence of SCSB was 7.8% of all patients with a
Between 1996 and 2003, 16 patients (nine female, seven male) were treated for a
Aims. Extendible endoprostheses have been available for more than 30
years and have become more sophisticated with time. The latest generation
is ‘non-invasive’ and can be lengthened with an external magnetic
force. Early results have shown a worryingly high rate of complications
such as infection. This study investigates the incidence of complications
and the need for further surgery in a cohort of patients with a
non-invasive growing endoprosthesis. Patients and Methods. Between 2003 and June 2014, 50 children (51 prostheses) had a
non-invasive growing prosthesis implanted for a
Intra-articular (IA) tumours around the knee are treated with extra-articular (EA) resection, which is associated with poor functional outcomes. We aim to evaluate the accuracy of MRI in predicting IA involvement around the knee. We identified 63 cases of high-grade sarcomas in or around the distal femur that underwent an EA resection from a prospectively maintained database (January 1996 to April 2020). Suspicion of IA disease was noted in 52 cases, six had IA pathological fracture, two had an effusion, two had prior surgical intervention (curettage/IA intervention), and one had an osseous metastasis in the proximal tibia. To ascertain validity, two musculoskeletal radiologists (R1, R2) reviewed the preoperative imaging (MRI) of 63 consecutive cases on two occasions six weeks apart. The radiological criteria for IA disease comprised evidence of tumour extension within the suprapatellar pouch, intercondylar notch, extension along medial/lateral retinaculum, and presence of IA fracture. The radiological predictions were then confirmed with the final histopathology of the resected specimens.Aims
Methods
Background. Dislocation is a common complication after proximal and total femur prosthesis reconstruction for
The June 2024 Oncology Roundup360 looks at: Chondrosarcoma of the femur: is local recurrence influenced by the presence of an extraosseous component?; Diagnostic challenges in low-grade central osteosarcoma; Single osteotomy technique for frozen autograft (pedicled freezing) in patients with malignant bone tumours; Unplanned resection for small superficial soft-tissue sarcomas: disastrous or simply bad?; Inactivation and replantation of the knee joint: an infeasible surgical method; Active surveillance of diffuse-type tenosynovial giant cell tumours: a retrospective, multicentre cohort study.
Venous tumour thrombus (VTT) is a rare finding in osteosarcoma. Despite the high rate of VTT in osteosarcoma of the pelvis, there are very few descriptions of VTT associated with extrapelvic primary osteosarcoma. We therefore sought to describe the prevalence and presenting features of VTT in osteosarcoma of both the pelvis and the limbs. Records from a single institution were retrospectively reviewed for 308 patients with osteosarcoma of the pelvis or limb treated between January 2000 and December 2022. Primary lesions were located in an upper limb (n = 40), lower limb (n = 198), or pelvis (n = 70). Preoperative imaging and operative reports were reviewed to identify patients with thrombi in proximity to their primary lesion. Imaging and histopathology were used to determine presence of tumour within the thrombus.Aims
Methods
The December 2023 Children’s orthopaedics Roundup360 looks at: A comprehensive nonoperative treatment protocol for developmental dysplasia of the hip in infants; How common are refractures in childhood?; Femoral nailing for paediatric femoral shaft fracture in children aged eight to ten years; Who benefits from allowing the physis to grow in slipped capital femoral epiphysis?; Paediatric patients with an extremity bone tumour: a secondary analysis of the PARITY trial data; Split tibial tendon transfers in cerebral palsy equinovarus foot deformities; Liposomal bupivacaine nerve block: an answer to opioid use?; Correction with distal femoral transphyseal screws in hemiepiphysiodesis for coronal-plane knee deformity.