Background. The posterior slope of the tibial component in total knee arthroplasty (TKA) has been reported to vary widely even with computer assisted surgery. In the present study, we analyzed the influence of posterior tibial slope on one-year postoperative clinical outcome after posterior-stabilized (PS) -TKA to find out the optimal posterior slope of tibial component. Materials and Method. Seventy-three patients with varus type osteoarthritic (OA) knees underwent PS-TKA (Persona PS. R. ) were involved in this study. The mean age was 76.6 years old and preoperative HKA angle was 14.3 degrees in varus. Tibial bone cut was performed using standard extra-medullary guide with 7 degrees of posterior slope. The tibial slopes were radiographically measured by post-operative lateral radiograph with posterior inclination in plus value. The angle between the perpendicular line of the proximal fibular shaft axis and the line drawn along the superior margin of the proximal tibia represented the tibial slope angle. We assessed one-year postoperative clinical outcomes including active range of motion (ROM), patient satisfaction and symptoms scores using 2011 Knee Society Score (2011 KSS). The influences of posterior tibial slope on one-year postoperative parameters were analyzed using simple linear regression analysis (p<0.05). Results. The average posterior tibial slope was 6.4 ± 2.0 °. The average active ROM were −2.4 ± 6.6 ° in extension and 113.5± 12.6 ° in flexion. The mean one-year postoperative patient satisfaction and symptom scores were 29.3 ± 6.4 and 19.6 ± 3.9 points respectively. The active knee extension, satisfaction and symptom scores were significantly negatively correlated to the posterior tibial slope (r = −0.25, −0.31, −0.23). Discussion. In the present study, we have found significant influence of the posterior tibial slope on the one-year postoperative clinical outcomes in PS-TKA. The higher posterior slope would induce flexion contracture and deteriorate patient satisfaction and symptom. We had reported that the higher tibial posterior slope increased flexion gap and the component gap change during knee flexion in PS-TKA. Furthermore, another study reported that increase of the posterior tibia slope reduced the tension in the collateral ligaments and resulted in the knee laxity at flexion. The excessive posterior slope of tibial component would result in flexion instability, and adversely affected the clinical results including patient satisfaction and symptom. Conclusion. In the PS-TKA for varus type OA knees, excessive tibial posterior slope was found to adversely affect one-year postoperative knee extension and clinical outcome including patient satisfaction and symptom. Surgeons should aware of the importance of tibial slope on one-year postoperative clinical results and pay more attentions to the posterior tibial slope angle not to be excessive

Anthropometric anatomical factors may influence mechanical and functional stability of joints. An increased posterior tibial slope places the anterior cruciate ligament at a theroretical biomechanical disadvantage. An increased posterior tibial slope can potentially alter forces during landing tasks by either increasing anterior tibial translation and/or ACL loading. The purpose of this study is to investigate the relationship between posterior tibial slope and anterior cruciate ligament injuries. It is hypothesised that subjects with an ACL injury have an increased posterior tibial slope compared to a normal population. Posterior tibial slope in 211 patients (154 male, 57 female), aged 15–49, who underwent anterior cruciate ligament reconstruction was measured using the posterior tibial cortex as reference. A matched control group was used for comparison. The average posterior tibial slope in the ACLR population was 6.1 degrees, whilst the control group had average values of 5.4 degrees. This finding nearly reached statistical significance (p=0.057). In the male population, average values were 5.5 degrees in the ACLR group and 5.9 in the control group. This was not significant (p=0.21). However, there was a significant difference (p=0.04) in the female group. ACLR females had higher values 6.5 degrees whereas the control group had average values of 5.2 degrees. Increased posterior tibial slope decreases the inclination of the ACL and potentially decreases vector force during dynamic tasks. We could not confirm the results of previous studies demonstrating an increased degree of posterior tibial slope in ACL injured patients. However, we demonstrated a significant difference in tibial slope in females. Based on our results, an increased posterior tibial slope is not a risk factor in males but possibly contributes to ACL injuries in females. Increased posterior tibial slope may be one of the reasons why females have a higher incidence of ACL injuries

Introduction. The influences of posterior tibial slope on the knee kinematics have been reported in both TKA and UKA. We hypothesized the posterior tibial slope (PTS) would affect the sagittal knee alignment after UKA. The influences of PTS on postoperative knee extension angle were investigated with routine lateral radiographies of the knee after UKA. Materials & Methods. Twenty-four patients (26 knees; 19 females, 7 males) underwent medial UKA were involved in this study. Average age was 74.8 ± 7.2 years. The mean preoperative active range of motion were − 4.1° ± 6.3°in extension and 123.2° ± 15.5° in flexion. All UKAs were performed using fixed bearing type UKA (Zimmer Biomet, ZUK), with adjusting the posterior slope of the proximal tibial bone cut according to the original geometry of the tibia. Routine lateral radiographies of the knee were examined preoperatively, 6 months after the surgery. PTS and knee extension angles with maximal active knee extension (mEXT) and one-leg standing (sEXT) were radiographically measured. We used the fibular shaft axis (FSA) for the sagittal mechanical axis of the tibia. PTS was defined as the angle between the medial tibial plateau and the perpendicular axis of FSA. Extension angles (mEXT and sEXT) were defined as the angles between FSA and distal femoral shaft axis (positive value for hyperextension). The changes of PTS and the influences of PTS on sEXT at each time period were analyzed using simple linear regression analysis (p<0.05). Results. The mean PTSs were 10.0° ± 3.0° and 9.9° ± 2.7° preoperatively, 6m after surgery respectively. The mean mEXTs were −4.1° ± 6.3° and −2.0° ± 5.4°, and sEXTs were −9.4° ± 7.6° and −7.3° ± 6.7° at each time period. Preoperative and postoperative PTS had positive correlation (r = −0.65). PTS significantly negatively correlated to sEXT at 6 months after the surgery (r = −0.63). Discussions. We found patient tended to stand with slight knee flexion (sEXT) which was smaller than the flexion contracture measured by mEXT. Interestingly, postoperative PTS significantly correlated to the knee flexion angle during one-leg standing. Patients with the higher PTS after UKA were more likely to stand with the higher knee flexion. The higher PTS had been reported to increase tibial anterior translation and strain or tear of the anterior cruciate ligament with load bearing in the normal knee. Slight knee flexion during one-leg standing would be beneficial to keep the joint surface parallel to the ground depending on PTS and reduce the anterior shearing force on the tibia after UKA. Conclusion. Postoperative posterior tibial slope reduced knee extension angle during one-leg standing after UKA. For any figures or tables, please contact authors directly

INTRODUCTION. Total knee arthroplasty (TKA) is an effective technique to treat end-stage osteoarthritis of the knee. One important goal of the procedure is to restore physiological knee kinematics. However, fluoroscopy studies have consistently shown abnormal knee kinematics after TKA, which may lead to suboptimal clinical outcomes. Posterior slope of the tibial component may significantly impact the knee kinematics after TKA. There is currently no consensus about the most appropriate slope. The goal of the present study was to analyze the impact of different prosthetic slopes on the kinematics of a PCL-preserving TKA. The tested hypothesis was that the knee kinematics will be different for all tested tibial slopes. MATERIAL. PCL-retaining TKAs (Optetrak Logic CR, Exactech, Gainesville, FL) were performed by fellowship trained orthopedic surgeons on six fresh frozen cadaver with healthy knees and intact PCL. The TKA was implanted using a computer-assisted surgical navigation system (ExactechGPS®, Blue-Ortho, Grenoble, FR). The implanted tibial baseplate was specially designed (figure 1) to allow modifying the posterior slope without repeatedly removing/assembling the tibial insert with varying posterior slopes, avoiding potential damages to the soft-tissue envelope. METHODS. Knee kinematics was evaluated by performing a passive range of motion (ROM) from full extension to at least 100 degrees of flexion. Passive ROM was repeated three times at each of the 4 posterior slopes selected: 10°, 7°, 4°, and 1° using the adjustable tibial component (figure 1). Respective 3D positioning of femur and tibia implants was recorded by the navigation system. Hip-knee-ankle (HKA) angle, femoro-tibial antero-posterior (AP) translation and internal-external (I/E) rotation were plotted according to the knee flexion angle. RESULTS. HKA angle (figure 2B): all 4 different tibial slopes induced a physiologic motion curve, and the kinematic differences between 10°, 7°, 4°, and 1° of posterior slope with the native knee were small. All slopes induced a varus angle beyond 60° of flexion, most likely was due to the external rotation of the femoral component. Femoro-tibial AP translation (figure 2C): all 4 different tibial slopes induced a physiologic motion curve and all slopes induced a large posterior translation before 80° of flexion, which was proportional to the slope. I/E rotation (figure 2A): all slopes induced an excessive internal rotation before 60° of flexion. DISCUSSION. A change in the tibial slope may impact significantly the TKA kinematics. Slopes of 1° and 4° seemed to be the better compromise with the specific implant used. Navigation systems are able to assess the knee kinematics after TKA. The test protocol has been assessed for reproducibility in a separate study with satisfactory results. Changing the tibial slope significantly impacted the TKA kinematics. With the specific implant used, rotational and coronal kinematics was only marginally impacted by the change in tibial slope. AP kinematics was significantly impacted by the change in tibial slope. These changes may be related to a change in the PCL strain. Slopes of 1° and 4° induced the more physiologic compromise

Total knee arthroplasty (TKA) is an effective technique to treat end-stage knee osteoarthritis, targeting the restore a physiological knee kinematics. However, studies have shown abnormal knee kinematics after TKA which may lead to suboptimal clinical outcomes. Posterior slope of the tibial component may significantly impact the knee kinematics. There is currently no consensus about the most appropriate slope. The goal of the present study was to analyse the impact of different prosthetic slopes on the kinematics of a PCL-preserving TKA, with the hypothesis that posterior slopes can alter the knee kinematics. A PCL-retaining TKA (Optetrak CR, Exactech, Gainesville, FL) was performed by a board-certified orthopaedic surgeon on one fresh frozen cadaver that had a non arthritic knee with an intact PCL. Intact knee kinematic was assessed using a computer-assisted orthopaedic surgery (CAOS) system (ExactechGPS®, Blue-Ortho, Grenoble, FR) Then, TKA components were implanted using the guidance of the CAOS system. The implanted tibial baseplate was specially designed to allow modifying the posterior slope without repeatedly removing/assembling the tibial insert with varying posterior slopes, avoiding potential damages to the soft-tissue envelope. Knee kinematic was evaluated by performing a passive range of motion 3 separate times at each of the 4 posterior slopes: 10°, 7°, 4° and 1°, and recorded by the navigation system. Femorotibial rotation, antero-posterior (AP) translation and hip-knee-ankle (HKA) angle were plotted with regard to the knee flexion angle. Tibial slopes of 1° and 4° significantly altered the normal rotational kinematics. Tibial slopes of 7° and 10° led to a kinematics close to the original native knee. All tibial slopes significantly altered the changes in HKA before 90° of knee flexion, without significant difference between the different slopes tested. The magnitude of change was small. There was no significant change in the AP kinematics between native knee and all tested tibial slopes. Changing the tibial slope significantly impacted the TKA kinematics. However, in the implant studied, only the rotational kinematics were significantly impacted by the change in tibial slope. Tibial slopes of 7° and 10° led rotational kinematics that were closest to that of a normal knee. Alterations in knee kinematics related to changing tibial slope may be related to a change in the PCL strain. However, these results must be confirmed by other tests involving more specimens

Introduction. Pre-clinical assessment of total knee replacements (TKR) can provide useful information about the constraint provided by an implant, and therefore help the surgeon decide the most appropriate configurations. For example, increasing the posterior tibial slope is believed to delay impingement in deep flexion and thus increase the maximal flexion angle of the knee, however it is unclear what effect this has on anterior-posterior (AP) constraint. The current ASTM standard (F1223) for determining constraint gives little guidance on important factors such as medial- lateral (M:L) loading distribution, flexion angle or coupled secondary motions. Therefore, the aim of the study was to assess the sensitivity of the ASTM standard to these variations, and investigate how increasing the posterior tibial slope affects TKR constraint. Methods. Using a six degree of freedom testing rig, a cruciate-retaining TKR (Legion; Smith & Nephew) was tested for AP translational constraint. In both anterior and posterior directions, the tibial component was displaced until a ‘dislocation limit’ was reached (fig. 1), the point at which the force-displacement graph started to plateau (fig. 2). Compressive joint loads from 710 to 2000 N, and a range of medial-lateral (M:L) load distributions, from 70:30% to 30:70% M:L, were applied at different flexion angles with secondary motions unconstrained. The posterior slope of the tibial component was varied at 0°, 3°, 6° and 9°. Results. AP translation was significantly larger at 60° and 90° flexion (22 ± 1 mm and 24 ± 1 mm respectively) than at 0° (14 ± 1 mm), whilst increasing the compressive joint load increased the force required to translate the tibia to limits of AP constraint at all flexion angles tested. When the M:L load distribution was shifted medially, a coupled internal rotation was observed with anterior translation and external rotation with posterior translation; this was reversed with a lateral shift in load distribution. It was also found that increasing the posterior slope of the tibial tray moved the neutral position of the tibia relative to the femur more anteriorly at all flexion angles tested. The constraint under anterior drawer was then reduced with increasing slope, which meant that the tray dislocated at lower drawer force and translations. Conclusions. When intraoperative tibial bone cuts are made, surgeons should be aware that by increasing posterior slope angles the TKR may offer less anterior constraint under body-weight loads, therefore relying more heavily on surrounding soft-tissue and muscle action to prevent dislocation. The ASTM test protocol could be refined to stipulate the variation of the M:L loading distribution. It has been shown to vary between patients and activities, and the AP constraint and associated secondary motions in this study were very sensitive to this distribution. The secondary motions observed should be measured and recorded to provide more information about the device's stability characteristics. The tests could also be extended to include a higher axial load such as 2000 N, approximately three times body weight, in order to investigate coupled rotations and M:L distribution effects whilst under normal walking gait loads

Purpose:. A higher posterior tibial slope can potentially result in kinetic and kinematic changes of the knee. These changes may influence knee functionality in ACL-deficient and ACL-reconstructed subjects. The purpose of this study was to investigate the relationship between knee functionality and posterior tibial slope in ACL-deficient and ACL-reconstructed subjects. Methods:. Subjects with isolated ACL injuries and subjects who underwent ACL-reconstruction with bone-patella-bone-tendon (BPTP) between 18 and 24 months post surgery were included in the study. Posterior tibial slope was measured on a lateral radiograph using the posterior tibial cortex as a reference. The Cincinnati scoring system was used to assess knee functionality. Results:. 44 ACL-deficient patients with a mean age of 26.6 years and 24 ACL-reconstructed patients with a mean age of 27.2 (25–49) years were included. The posterior tibial slope in the ACL-deficient group averaged 6.10±3.57 degrees (range 0–17 degrees) and 7.20±4.49 degrees (range 0–17) in the ACL-reconstructed group. An anterior tibial slope was not measured in any of the participants. The mean Cincinnati score in the ACL-deficient subject was 62.0±14.5 and 89.3±9.5 in the ACL-reconstructed subject. There was a moderate but non-significant correlation (r=0.47) between knee functionality and slope in the ACL-deficient subject. Dividing posterior tibial slope into intervals, a strong significant correlation (r=0.91, p=0.01) was observed between knee functionality and slope. There was a weak but non-significant correlation (r=0.24) between knee functionality and slope in the ACL-reconstructed patient. Dividing posterior tibial slope into intervals (0–4, 5–9, >10) a strong and significant correlation (r=0.96, p=0.0001) was observed between knee functionality and slope. Conclusion:. The results of this study suggest that subjects with a higher posterior tibial slope have higher knee functionality. This is in contrast to previous research

A higher posterior tibial slope can potentially result in kinetic and kinematic changes of the knee. These changes may influence knee functionality in ACL-deficient and ACL-reconstructed subjects. The purpose of this study is to investigate the relationship between knee functionality and posterior tibial slope in ACL-deficient and ACL-reconstructed subjects. Subjects with isolated ACL injuries and subjects who underwent ACL- reconstruction with BPTP between 18 and 24 months post surgery were included in the study. Posterior tibial slope was measured on a lateral radiograph using the posterior tibial cortex as a reference. The Cincinnati scoring system was used to assess knee functionality. Frty-four ACL-deficient patients with a mean age of 26.6 years, and 44 ACL-reconstructed patients with a mean age of 27.2 (25–49) years were included. The posterior tibial slope in the ACL-deficient group averaged 6.10±3.57 degrees (range 0–17 degrees) and 7.20±4.49 degrees (range 0–17) in the ACL-reconstructed group. The mean Cincinnati score in the ACL-deficient subject was 62.0±14.5 and 89.3±9.5 in the ACL-reconstructed subject. There was a moderate but non-significant correlation (r=0.47) between knee functionality and slope in the ACL-deficient subject. By dividing posterior tibial slope into intervals, a strong significant correlation (r=0.91, p=0.01) was observed between knee functionality and slope. There was a weak but non-significant correlation (r=0.24) between knee functionality and slope in the ACL-reconstructed patient. Dividing posterior tibial slope into intervals (0-4, 5-9, >10) a strong and significant correlation (r=0.96, p=0.0001) was observed between knee functionality and slope. The results of this study suggest that subjects with a higher posterior tibial slope have higher knee functionality. This is in contrast to previous research

Aim. To assess the influence of posterior slope on Knee flexion and function in Asian and Caucasian populations. Material & methods. We have conducted a prospective comparative study of 109 Asian and Caucasian posterior tibial slopes. All data has been collected prospectively and includes personal data (height, weight, tibial measurements), ASA grading, knees scores and range of movement. Analysis was performed for the whole group and comparisons were made between the two sets of patients. Minimum follow-up was two years. Results and conclusion. Patients were well-matched for Age, Sex and ASA grading at time of surgery. The system for TKR we used aims for a slope of 5 degrees. The average posterior slope in Caucasian patients was 3.9 degrees pre-TKR and 4.55 degrees post-TKR. However in Asian patients the average slope was 10 degrees pre-TKR and 4.45 degrees post-TKR. We have analysed the significance of this change in Asian patients and compared this with data for range of movement and Knee score at a minimum of two years. The Asians tend to have greater pre-operative posterior slopes as compared to Caucasians. The changes in knee flexion, knee scores and knee functions (Knee Society Clinical Rating Systems Scores) in the two groups were not statistically significant. Although previous studies have shown that decreasing the posterior slope would reduce the range of flexion after TKR, our study has shown that posterior slope has no role in changes in knee flexion, knee scores and knee functions. We therefore feel that increased posterior tibial slope in Asian patients should not deter one from changing their practice of using normal tibial cuts as final post-operative results have no bearing on it

PURPOSE:. Unicompartmental knee arthroplasty (UKA) is becoming more commonly performed and is more technically challenging than total knee replacement. Retention of the anterior and posterior cruciate ligaments requires more accurate re-creation of the patient's normal anatomic posterior slope with UKA. Purpose of this study was to accurately determine the posterior tibial slope in patients having medial or lateral UKA performed. METHODS:. Retrospective review was performed of 2,395 CT scans performed for a customized UKA implant. Standard CT technique was used and the posterior slope was measured on the involved side of the proximal tibia. RESULTS:. CT measurements from 2031 knees undergoing medial UKAs had an average pre-operative posterior slope of 6.8 deg (SD 3.3), in these patients the posterior slope was between: 0–4 deg in 430 knees (21.2%), 4–7 deg in 696 knees (34.3%), 7–10 deg in 545 knees (26.8%), >10 deg in 360 knees (17.7%), and 13 knees (0.6%) had a reversed (anterior) tibial slope. Measurements from the 364 knees undergoing lateral UKAs showed an average pre-operative posterior slope of 8.0 deg (SD 3.3), in these patients the posterior slope was between: 0–4 deg in 43 knees (11.8%), 4–7 deg in 100 knees (27.5%), 7–10 deg in 118 knees (32.4%), >10 deg in 103 knees (28.3%), and 1 knee (0.3%) had a reversed (anterior) tibial slope. CONCLUSION:. There is marked variability in the posterior slope of the proximal tibial with 44.5% of medial plateaus and 60.7% of lateral plateaus having more than 7 deg of posterior slope pre-operatively. This is the first large CT based review of posterior slope variation of the proximal tibia. If attempting to match the patient's proximal slope during UKA, a routine setting of 5 degrees posterior slope will produce a posterior slope less than the patient's native anatomy in more than 50% of patients

Introduction. Optimal alignment of the tibial component in TKA is an important consideration. General agreement exists on the appropriate coronal alignment. However there is no consensus on sagittal alignment (posterior slope). Some surgeons target a fixed posterior slope (usually between 0 and 10 degrees), while others attempt to match the patient's intrinsic anatomy. The purpose of this study was to evaluate the tibial posterior slope in patients undergoing TKA. Methods. 13,586 CT scans of patients undergoing patient specific were analyzed. Three-dimensional reconstructions were performed and the posterior tibial slope was measured. Mean slope and ranges were determined. Results. Mean tibial posterior slope was 7.2 +/− 3.7 degrees (range −5 to 25 deg.) 35% of patients had tibial slope measurements more than 3 degrees different from the mean slope of this population. Conclusion. This study demonstrated a remarkable variability of tibial slope in patients undergoing TKA. This information may be useful to surgeons in determining “optimum” sagittal alignment of the tibial component for an individual patient. A patient with preoperative tibial slope very different from “average” may be at risk for sagittal malalignment of the tibial component. Additionally, large preoperative to postoperative changes in tibial slope may adversely affect knee kinematics and clinical outcome

The purpose of this study was to compare posterior tibial slope preoperatively and postoperatively in patients undergoing navigational opening-wedge High tibial osteotomy (HTO) and to compare posterior slope changes for 2 and 3-dimentional (D) navigation versions. Between May 2009 and September 2010, 35 patients with unicompartmental osteoarthritis and varus deformity were treated by navigation-assisted open-wedge HTO. Patients were randomly divided into two groups according to the version of the Orthopilot (Aesculap) navigation system used; 2D group (18 patients, 2-D version) and 3D group (17 patients, 3-D version). Radiologic evaluations were conducted using pre- and postoperative leg axes. Posterior slope of proximal tibiae were measured using the proximal tibial anatomic axis method. Postoperatively the mechanical axis was corrected adequately to a mean valgus of 2.81° in 2D group and of 3.15° in 3D group. Mean posterior slopes were well maintained, and measured 7.9° and 10.3° preoperatively and 8.99° and 9.14° postoperatively in 2D and 3D groups, respectively. No significant difference was found between the two navigation versions with respect to posterior tibial slope; mean tibial slope changes were 1.09° and −0.2° in 2D and 3D groups (p = 0.04). Navigation-assisted opening-wedge HTO greatly improves the accuracy of the desired postoperative mechanical femorotibial axis and posterior tibial slope, and the use of 3D navigation results in significantly less change in posterior tibial slope. The authors recommend the use of the 3D navigation because they provide real time intraoperative information about coronal, sagittal, and transverse axis, which are important for the maintenance of a normal posterior tibial slope

We designed this study to determine the clinical evidence to support use of the five degree tibial extra-medullary cutting block over the zero degree cutting block. We identified three groups of patients from the databases and clinical notes at St Michaels Hospital, Toronto. Group one were primary total knees performed using the five degree cutting block, group two were primary total knees performed using the zero degree cutting block and the third group were computer navigated primary total knees. Patients in all three groups were age and sex matched. The senior author advocating use of the five degree block aimed to obtain a five degree posterior slope. The senior author who advocated the use of computer navigation, or the traditional zero degree cutting block, aimed to obtain a three degree posterior slope. All operations were performed by residents or clinical fellows, under the supervision of the senior authors. Patient radiographs were assessed to obtain the optimal direct lateral view obtained and they were saved on a database. Two independent blinded researchers assessed the posterior slope using Siemens Magicweb Software Version VA42C_0206. Two methods were used and the results averaged. The average posterior slope for the navigated total knee replacements was 0.1 degrees (−2 to 4). The average posterior slope for the five degree cutting block was 5.2 degrees (−2 to 16). The average posterior slope for the zero degree block was 3.79 degrees (−2 to 13). Computer navigated knee arthroplasty patients had significantly less variation in outlier measurements compared to the traditionally jigged arthroplasty patients. They were however, less accurate. The five degree cutting block tended to provide a more consistent posterior slope angle, but both the five degree and zero degree cutting blocks had variability in outliers. Computer Navigated Total Knee replacement provides a more consistent and reproducible tibial cut with less variability in alignment than extra-medullary jigs. The traditional five degree cutting block tended to provide a more reliable five degree posterior slope than the zero degree block, but was still subject to outliers

The influence of amount of tibial posterior slope changes on joint gap and postoperative range of motion was investigated in 35 patients undergoing unicompartmental knee arthroplasty (UKA). Component gap between the medial tibial osteotomy surface and the femoral trial prosthesis was measured throughout the range of motion using a tensor. The mean tibial posterior slope decreased from 10.2 to 7.3 degrees. Increased tibial slope change was positively correlated with component gap differences of 90° −10°, 120° −10°, and 135° −10° and negatively correlated with postoperative extension angle. Increasing tibial slope should be avoided to achieve full extension angle after UKA

Background. Adjusting the joint gap length to be equal in both extension and flexion is an important issue in total knee arthroplasty (TKA). Tight flexion gaps occur sometimes, particularly with the cruciate-retaining (CR) type of TKA, and it impede knee flexion. In posterior stabilizing (PS) TKA, because sacrificing the PCL increases the flexion gap, the issue of gap balancing with PS-TKA is usually focused on decreasing the enlarged flexion gap to be equal to the extension gap. It is generally known that posterior tibial slope would affect the flexion gap, however, the extent to which changes in the tibial slope angle directly affect the flexion gap remains unclear. This study aimed to clarify the influence of tibial slope changes on the flexion gap in CR- or PS-TKA. Methods. The flexion gap was measured using a tensor device with the femoral trail component in 20 cases each of CR- and PS-TKA. A wedge plate with a 5° inclination was placed on the tibial cut surface by switching its front–back direction to increase or decrease the tibial slope by 5°. The flexion gap in changing the tibial slope was compared to that of the neutral slope measured with a flat plate that had the same thickness of the wedge plate center. Results. When the tibial slope decreased or increased by 5°, the flexion gap decreased or increased by 1.9 ± 0.6 mm or 1.8 ± 0.4 mm, respectively, with CR-TKA and 1.2 ± 0.4 mm or 1.1 ± 0.3 mm, respectively, with PS-TKA. Conclusions. The influence of changing the tibial slope by 5° on the flexion gap was approximately 2 mm with CR-TKA and 1 mm with PS-TKA. Clinical relevance. This information is useful to consider the effect of manipulating the tibial slope on the flexion gap when performing CR- or PS-TKA

The posterior tibial slope angle (PTS) in posterior cruciate retaining total knee arthroplasty influences the knee kinematics, knee stability, flexion gap, knee range of motion (ROM) and the tension of the posterior cruciate ligament (PCL). The current technique of using an arbitrary (often 3–5 degrees) PTS in all cases seldom will restore native slope in cruciate retaining TKA. Questions/Purposes: The primary objective was to determine if we could surgically reproduce the native PTS in cruciate-retaining total knee arthroplasty. The second objective was to determine if reproduction of native slope was significant – ie influenced clinical outcome. We evaluated the radiographic and clinical outcomes of a series of consecutive total knee arthroplasties using the PFC sigma cruciate-retaining total knee system in 215 knees. The tibial bone cut was planned to be parallel to the patient's native anatomical slope in the sagittal plane. An “Angel Wing” instrument was placed on the lateral tibial plateau and the slope of the cutting guide adjusted to make the cutting block parallel to the patient's native tibial slope. All true lateral radiographs of the knee were measured for PTS using a picture achieving and communication system (PACS). PTSs were measured with reference to the proximal tibial medullary canal (PTS-M) and the proximal tibial anterior cortex (PTS-C). The knee ROM, Knee Society Score, Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and SF-12 at the last follow-up were evaluated as clinical outcomes. The mean preoperative PTS-M was 6.9±3.3 degrees and the mean postoperative PTS-M was 7±2.4 degrees. The mean preoperative PTS-C was 12.2±4.2 degrees and the mean postoperative PTS-M was 12.6±3.4 degrees. There was no significant difference form the preoperative and postoperative PTS measurement in both techniques (p>0.05). We used an arbitrary 3 degrees as an acceptable range for PTS-M reproduction. The PTS-M was reproduced within 3 degrees in 144 knees (67%); designated as Group A. The 71 knees with a difference more than 3 degrees in (33%) were designated as Group B. Group A showed significantly larger gain in ROM compared with group B (p=0.04). Group A also had significantly better improvement in Knee society score and WOMAC score and SF-12 physical score when compare with group B (p<0.01). Our modification of standard surgical technique reliably reproduced the native tibial slope in cruciate-retaining total knee arthroplasty. More importantly, reproduction of the patient's native PTS within 3 degrees resulted in better clinical outcomes manifested by gain in ROM and knee functional outcome scores

Introduction. Medial open wedge high tibial osteotomy (HTO) is a generally accepted surgical method for medial unicompartmental osteoarthritis with varus malalignment of the lower extremity. However, several authors have suggested the possibility of unintentional secondary changes during open wedge HTO, which include posterior tibial slope angle (PTS) change, tibial rotation change and medial–lateral slope change of the knee joint line, may influence knee kinematics and produce poor clinical outcomes. We sought to analyze postoperative changes in three-dimensional planes using a virtual wedge osteotomy 3D model. Pre- and post-operative changes in the medial proximal tibial angle (MPTA) in the coronal plane, posterior tibial slope (PTS) in the sagittal plane, and axial tibial rotation were measured as dependent variables. And this study was attempted to determine their mutual relationships and to clarify which independent variables, including hinge axis angle and gap ratio, affect tibial rotation change and PTS change by applying the identified hinge position. Method. A total of 17 patients with 19 knees underwent HTO and were evaluated with 3D-CT before and after surgery. A 3D model was constructed by applying reverse engineering software. Results. No significant linear correlation was observed between the three dependent variables: MPTA, PTS, and rotational change. Gap ratio (β = −0.2830, p = 0.0007) and hinge axis angle (β = 0.7395, p = 0.0005) were significant factors in determining rotation change with moderate correlation (R2 = 0.546 and 0.520, respectively). In univariate regression analysis, gap ratio (p = 0.6284) and hinge axis angle (p = 0.0968) were not significant factors determining the PTS; however, after controlling for confounder, rotation change, they became statistically significant (hinge axis: β = 0.44, p = 0.0059; gap ratio: β = 0.14, p = 0.0174). Discussion and Conclusion. Unchanged axial rotation is a requisite for constant unchanged PTS, and hinge axis angle have to be considered as an important independent variable for limitation of unintended secondary changes. This study might provide clues about the low reliability of intact slope angle, That is, representability of gap ratio as slope change can be interfered by rotational change, as a confounder. Also, the current study reported the external rotation tendency of proximal tibia with increasing hinge axis angle

Introduction. Total knee arthroplasty (TKA) can effectively treat end-stage knee osteoarthritis. For cruciate-retaining (CR) TKA, the posterior tibial slope (PTS) of the reconstructed proximal tibia plays a significant role in restoring normal knee kinematics as it directly affects the tension of the posterior cruciate ligament (PCL) [1]. However, conventional cadaveric testing of the impact of PTS on knee kinematics may damage/stretch the PCL, therefore impact the test reproducibility. The purpose of this study was to assess the reproducibility of a novel method for the evaluation of the effects of PTS on knee kinematics. Materials and Methods. Cemented CR TKAs (Logic CR, Exactech, Gainesville, FL, USA) were performed using a computer-assisted surgical guidance system (ExactechGPS®, Blue-Ortho, Grenoble, FR) on six fresh frozen non-arthritic knees (PCL presumably intact). The tibial baseplate was specially designed (Fig. 1) with a mechanism to modify the PTS in-situ. Knee kinematics, including anteroposterior (AP) translation, internal/external (IE) rotation, and hip-knee-ankle angles, were evaluated by performing a passive range of motion from extension up to ∼110° of flexion, three separate times at 5 PTSs: 10°, 7°, 4°, 1°, and then 10° again. The repeatability of the test was investigated by comparing the kinematics between the first and the last 10° tests. Any clinically relevant deviation (1.5° for the hip knee ankle angle, 1.5mm for anterior-posterior translation and 3° for internal-external rotation) would reflect damage to the soft-tissue envelope or the PCL during the evaluation. Potential damage of PCL was investigated by comparing the kinematic parameters from the first and last 10° slope tests at selected flexion angles (Table 1) by paired t-test, with statistical significance defined as p<0.05. Results. The differences in the kinematic parameters between the two sets of acquisitions at 10° of PTS were small, non-clinically relevant (Fig 2), and statistically insignificant (Table 1). For a given knee, the difference was relatively constant over the range of flexion. Knowing that the PCL is not active in extension and early flexion, this finding suggested the differences were mainly caused by the measurement noises. Discussion. The results suggested our test method does not significantly disrupt the soft tissue environment of the knee. Previous evaluations of the effect of the PTS on passive knee kinematics often overlooked the potential disruption/stretching of the PCL or other soft tissue over the course of aggressive manipulation of the PTS. Other soft tissue preserving test methods for the adjustment of PTS, such as anterior opening wedge osteotomy with gap filling using bone cement [2] but the preservation of the PCL over the course of the experiment hasn't been evaluated. The present study utilized a novel tibial baseplate, which allowed for adjusting the PTS without re-cutting the tibia and removing the components. Knee kinematics can therefore be reliably tested without disrupting the PCL or the soft tissue envelope. As such, the authors promote the proposed test method for future investigations

Introduction. The Oxford Unicompartmental Knee Replacement (OUKA) is the most popular unicompartmental knee replacement (UKR) in the New Zealand Joint Registry with the majority utilising cementless fixation. We report the 10-year radiological outcomes. Methods. This is a prospective observational study. All patients undergoing a cementless OUKA between May 2005 and April 2011 were enrolled. There were no exclusions due to age, gender, body mass index or reduced bone density. All knees underwent fluoroscopic screening achieving true anteroposterior (AP) and lateral images for radiographic assessment. AP assessment for the presence of radiolucent lines and coronal alignment of the tibial and femoral components used Inteliviewer radiographic software. The lateral view was assessed for lucencies as well as sagittal alignment. Results. 687 OUKAs were performed in 641 patients. Mean age at surgery was 66 years (39–90yrs), 382 in males and 194 right sided. 413 radiographs were available for analysis; 92 patients had died, 30 UKRs had been revised and 19 radiographs were too rotated to be analysed the remainder were lost to follow-up. Mean radiograph to surgery interval was 10.2 years (7.1–16.2yrs). RLLs were identified in zone 1 (3 knees), zone 2 (2 knees), zone 3 (3 knees), zone 5 (3 knees), zone 6 (2 knees) and zone 7 (42 knees). No RLL had progressed, and no case had any osteolysis or prosthesis subsidence. Alignment in the coronal plane: mean 2.90° varus (9.30° varus - 4.49° valgus) of the tibial component to the tibial anatomic axis and the femoral component in mean 4.57° varus (17.02° varus - 9.3° valgus). Sagittal plane posterior tibial slope was a mean 6.30° (0.44° -13.60° degrees) and mean femoral component flexion of 8.11° (23.70° flexion – 16.43° extension). Conclusion. The cementless OUKA demonstrates stable fixation with low revision rates at our centre supporting results earlier published by the design centre

Introduction. Opening wedge high tibial osteotomy is an attractive surgical option for physically active patients with early osteoarthritis and varus malalignment. Unfortunately use of this surgical technique is frequently accompanied by an unintended increase in the posterior tibial slope, resulting in anterior tibial translation, and consequent altered knee kinematics and cartilage loading(1). To address this unintended consequence, it has been recommended that the relative opening of the anteromedial and posterolateral corners of the osteotomy are calculated pre-operatively using trigonometry (1). This calculation assumes that the saw-cut is made parallel to the native posterior slope; yet given the current reliance on 2D images and the ‘surgeon's eye’ to guide the saw-cut, this assumption is questionable. The aim of this study was to explore how accurately the native posterior tibial slope is reproduced with a traditional freehand osteotomy saw-cut, and whether novel 3D printed patient-specific guides improve this accuracy. Methods. 26 fourth year medical students with no prior experience of performing an osteotomy were asked to perform two osteotomy saw-cuts in foam cortical shell tibiae; one freehand, and one with a 3D printed surgical guide (Embody, London) that was designed using a CT scan of the bone model. The students were instructed to aim for parallelity with a hinge pin which had been inserted (with the use of a highly conforming 3D printed guide) parallel to the posterior slope of the native joint. For the purpose of analysis, the sawbones were consistently orientated along their mechanical and anatomical tibial axes using custom moulded supports. Digital photographs taken in the plane of the osteotomy were analysed with ImageJ software to calculate the angular difference in the sagittal plane between the hinge-pin and saw-cut. Statistical analysis was performed with SPSS v21 (Chicago, Illinois); a paired t-test was used to compare the freehand and patient-specific guide techniques. Statistical significance was set at a p-value <0.05. Results. Using the traditional freehand technique, the mean difference in angle between the hinge pin and osteotomy saw-cut was 5.40 (SD 4.6), which contrasted with 1.40(SD 1) when the osteotomy was performed using a 3D printed guide [See Figure 1]. This difference was significant (p<0.001). Discussion. This study highlights the large degree of error in the posterior slope of an osteotomy saw-cut when performed using a freehand technique, and which is likely to be a factor in the unintended change in tibial slope commonly observed in post-operative patients. We found that a 3D printed patient-specific osteotomy guide significantly improved the accuracy and reduced the variability of this procedure. A follow-up multi-centre clinical trial is currently underway to ascertain whether these results are replicated in-vivo