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Bone & Joint Research
Vol. 7, Issue 4 | Pages 282 - 288
1 Apr 2018
Beckmann NA Bitsch RG Gondan M Schonhoff M Jaeger S

Objectives. In order to address acetabular defects, porous metal revision acetabular components and augments have been developed, which require fixation to each other. The fixation technique that results in the smallest relative movement between the components, as well as its influence on the primary stability with the host bone, have not previously been determined. Methods. A total of 18 composite hemipelvises with a Paprosky IIB defect were implanted using a porous titanium 56 mm multihole acetabular component and 1 cm augment. Each acetabular component and augment was affixed to the bone using two screws, while the method of fixation between the acetabular component and augment varied for the three groups of six hemipelvises: group S, screw fixation only; group SC, screw plus cement fixation; group C, cement fixation only. The implanted hemipelvises were cyclically loaded to three different loading maxima (0.5 kN, 0.9 kN, and 1.8 kN). Results. Screw fixation alone resulted in up to three times more movement (p = 0.006), especially when load was increased to 100% (p < 0.001), than with the other two fixation methods (C and SC). No significant difference was noted when a screw was added to the cement fixation. Increased load resulted in increased relative movement between the interfaces in all fixation methods (p < 0.001). Conclusion. Cement fixation between a porous titanium acetabular component and augment is associated with less relative movement than screw fixation alone for all implant interfaces, particularly with increasing loads. Adding a screw to the cement fixation did not offer any significant advantage. These results also show that the stability of the tested acetabular component/augment interface affects the stability of the construct that is affixed to the bone. Cite this article: N. A. Beckmann, R. G. Bitsch, M. Gondan, M. Schonhoff, S. Jaeger. Comparison of the stability of three fixation techniques between porous metal acetabular components and augments. Bone Joint Res 2018;7:282–288. DOI: 10.1302/2046-3758.74.BJR-2017-0198.R1


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 2 | Pages 158 - 162
1 Feb 2012
Sternheim A Backstein D Kuzyk PRT Goshua G Berkovich Y Safir O Gross AE

We report the use of porous metal acetabular revision shells in the treatment of contained bone loss. The outcomes of 53 patients with ≤ 50% acetabular bleeding host bone contact were compared with a control group of 49 patients with > 50% to 85% bleeding host bone contact. All patients were treated with the same type of trabecular metal acetabular revision shell. The mean age at revision was 62.4 years (42 to 80) and the mean follow-up of both groups was 72.4 months (60 to 102). Clinical, radiological and functional outcomes were assessed. There were four (7.5%) mechanical failures in the ≤ 50% host bone contact group and no failures in the > 50% host bone contact group (p = 0.068). Out of both groups combined there were four infections (3.9%) and five recurrent dislocations (4.9%) with a stable acetabular component construct that were revised to a constrained liner. Given the complexity of the reconstructive challenge, porous metal revision acetabular shells show acceptable failure rates at five to ten years’ follow-up in the setting of significant contained bone defects. This favourable outcome might be due to the improved initial stability achieved by a high coefficient of friction between the acetabular implant and the host bone, and the high porosity, which affords good bone ingrowth


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_11 | Pages 20 - 20
1 Aug 2018
Ohashi H Yo H Ikawa T Minami Y Teraoka T
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Reconstruction of massive acetabular bone defects in primary and revision THA is challenging for reconstructive joint surgeons. The use of porous metal augments is one of the options. The advantages of porous metal augments are easy to use, modularity and lack of resorption. We investigated the radiological results of porous metal augments used for massive acetabular bone defects in primary and revision THA. Forty-one hips in forty patients had porous metal augments between 2011 and 2016. Thirty of the procedures were revision arthroplasties and 11 were primary procedures (Crowe type III in 5 hips, Crowe type IV in 3, septic hip sequalae in 2 and RA in one). Four of the revisions were second-stage reimplantation after infection. The Paprosky classification for revision was 2B in 4 hips, 2C in one, 3A in 3 and 3B in 22. Regenerex augments were used in 39 hips and trabecular metal augments were used in 2. Thirty-six cups were cemented and 5 cups were uncemented. Mean follow-up was 37.6 months (range, 1–82). Radiographic findings of osteointegration between host bone and the porous metal augments were assessed. The presence or absence of radiolucent lines between cement or cup/host bone and augment/host bone interface was noted. Two revisions were performed due to infection, one month and 66 months after operation. The other implants were stable without any complications. Osteointegration between host bone and the porous metal augments were recognized in 36 hips. Radiolucent lines between cement/host bone interface, less than 1 mm in width, were visualized in 2 hips. Porous metal augments are convenient and our short-term results showed excellent radiological results for massive acetabular bone defects in primary and revision THA


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_3 | Pages 19 - 19
23 Feb 2023
Sandow M Cheng Z
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This paper presents an ongoing review of the use of a wedge-shaped porous metal augments in the shoulder to address glenoid retroversion as part of anatomical total shoulder arthroplasty (aTSA). Seventy-five shoulders in 66 patients (23 women and 43 men, aged 42 to 85 years) with Walch grade B2 or C glenoids underwent porous metal glenoid augment (PMGA) insertion as part of aTSA. Patients received either a 15º or 30º PMGA wedge (secured by screws to the native glenoid) to correct excessive glenoid retroversion before a standard glenoid component was implanted using bone cement. Neither patient-specific guides nor navigation were used. Patients were prospectively assessed using shoulder functional assessments (Oxford Shoulder Score [OSS], American Shoulder and Elbow Standardized Shoulder Assessment Form [ASES], visual analogue scale [VAS] pain scores and forward elevation [FE]) preoperatively, at three, six, and 12 months, and yearly thereafter, with similar radiological surveillance. Forty-nine consecutive series shoulders had a follow-up of greater than 24 months, with a median follow-up of 48 months (range: 24–87 months). Median outcome scores improved for OSS (21 to 44), ASES (24 to 92), VAS (7 to 0), and FE (90º to 140º). Four patients died, but no others were lost to follow-up. Apart from one infection at 18 months postoperatively and one minor peg perforation, there were no complications, hardware failures, implant displacements, significant lucency or posterior re-subluxations. Radiographs showed good incorporation of the wedge augment with correction of glenoid retroversion from median 22º (13º to 46º) to 4º. All but four glenoids were corrected to within the target range (less than 10º retroversion). The porous metal wedge-shaped augments effectively addressed posterior glenoid deficiency as part of aTSA for rotator cuff intact osteoarthritis, producing satisfactory clinical outcomes with no signs of impending future failure


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 267 - 267
1 Dec 2013
Cohen R
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Cementless biologic fixation surfaces on total joint replacement devices, such as those used in total hip and knee procedures, have evolved over the decades. Historically, various surfaces to allow bone ingrowth or ongrowth have been applied as a coating to a pre-formed solid metal substrate. As shown in Figure 1, from left to right, representative coating surfaces include sintered beads, diffusion-bonded fiber metal, and plasma sprayed titanium. In certain applications, tantalum porous metal (Fig 1, left) can be used without a solid metal substrate, but its most widespread usage is in a modular acetabular cup design with the porous metal diffusion-bonded to a solid metal substrate similar to other coatings. Each of these examples of biologic fixation surfaces has limitations. With comparatively low porosity, bead, fiber metal and plasma spray coatings are simply a surface enhancement onto a rigid machined, forged or cast metal substrate. Furthermore, the thermal process to apply the coatings can adversely affect the mechanical properties of the metal substrate. Released in the 1990's, tantalum porous metal is considered a ‘highly porous metal’ with twice the porosity of the applied surface coatings. With that greater porosity comes lower strength that requires engineers to make standalone tantalum porous metal shapes more bulky. The chemical deposition process to produce tantalum porous metal shapes has also limitations on geometry possibilities. Where bonding the tantalum porous metal to a solid metal substrate is necessary for adequate strength, that diffusion bonding process pressure can diminish the surface coefficient of friction necessary for initial stability. A new class of manufacturing processing, referred to as ‘additive manufacturing’, allows engineers to create unique porous configurations. These configurations can be fabricated with beneficial properties to a specific implant application. One such enabling additive manufacturing process is called direct metal laser sintering (DMLS). This process utilizes a laser that travels over a fine powder bed. The laser path is determined by a program that mimics a computer model. Where the laser contacts the powder bed, the powder consolidates. Layer by layer, a scaffold porous metal is fabricated. Figure 2 shows a titanium alloy porous metal structure produced by DMLS. This formed biomaterial has 65% porosity, a high coefficient of friction, low stiffness, and strength that is 2 to 3 times that of tantalum porous metal. From a design versatility perspective, with greater strength, relatively thinner and more bone conserving geometries can be developed. When a solid metal surface interface to secure a modular polymer bearing is required, the DMLS process can produce the solid surface and the porous metal at the same time. With no secondary bonding thermal cycle needed, the construct's mechanical integrity is not compromised. Advancing biologic fixation necessitates bone conserving implant designs that have the properties to achieve immediate mechanical stability and longer term bone ingrowth. This novel use of DMLS in this particular porous metal geometry allows engineers to meet those criteria


The Bone & Joint Journal
Vol. 106-B, Issue 4 | Pages 312 - 318
1 Apr 2024
Sheth NP Jones SA Sanghavi SA Manktelow A

The advent of modular porous metal augments has ushered in a new form of treatment for acetabular bone loss. The function of an augment can be seen as reducing the size of a defect or reconstituting the anterosuperior/posteroinferior columns and/or allowing supplementary fixation. Depending on the function of the augment, the surgeon can decide on the sequence of introduction of the hemispherical shell, before or after the augment. Augments should always, however, be used with cement to form a unit with the acetabular component. Given their versatility, augments also allow the use of a hemispherical shell in a position that restores the centre of rotation and biomechanics of the hip. Progressive shedding or the appearance of metal debris is a particular finding with augments and, with other radiological signs of failure, should be recognized on serial radiographs. Mid- to long-term outcomes in studies reporting the use of augments with hemispherical shells in revision total hip arthroplasty have shown rates of survival of > 90%. However, a higher risk of failure has been reported when augments have been used for patients with chronic pelvic discontinuity. Cite this article: Bone Joint J 2024;106-B(4):312–318


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_8 | Pages 61 - 61
1 May 2014
Berry D
Full Access

Highly porous metal surfaces have transformed acetabular revision surgery by providing (1) enhanced friction which potentially provides greater primary fixation, (2) enhanced bone ingrowth potential, (3) enhanced screw fixation options. These characteristics have led many surgeons to use these devices routinely in acetabular revision and have led to an expansion of the indications for porous uncemented hemispherical cups in acetabular revision. Mid-term results suggest that the historical indications for hemispherical cups in revision surgery can be moderately expanded with some implants with these characteristics. In a recent study of 3448 revision total hip arthroplasties, we found porous tantalum cups had a statistically lower revision rate than other materials/designs. Highly porous metals also have provided the options of metal augments to fill selected bone defects—which can both enhance cup fixation and manage bone loss simultaneously. A number of different highly porous metals are now available, and how each will perform is not yet known


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_11 | Pages 21 - 21
1 Aug 2018
Zhou Y
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Failed ingrowth and subsequent separation of revision acetabular components from the inferior hemi-pelvis constitutes a primary mode of failure in revision total hip arthroplasty (THA). Few studies have highlighted other techniques than multiple screws and an ischial flange or hook of cages to reinforce the inferior fixation of the acetabular components, nor did any authors report the use of porous metal augments in the ischium and/or pubis to reinforce inferior fixation of the acetabular cup. The aims of this study were to introduce the concept of inferior extended fixation into the ischium and/or pubis during revision total hip arthroplasty, and to answer the following questions: (1) what are early clinical outcomes using inferior extended fixation and (2) what are the radiographic outcomes of hips revised with inferior extended fixation?. Patients who underwent revision THA utilizing the surgical technique of inferior extended fixation with porous metal augments secured in the ischium and/or pubis in a single institution from 2014 to 2016 were reviewed. Twenty-four patients were initially identified, and 16 patients were included based on the criteria of minimum 18 months clinical and radiographic follow-up. The median HHS, as well as the SF-12 physical and mental components improved significantly at the latest follow-up (p<0.001). The WOMAC global score decreased significantly at the latest follow-up (p<0.001). All constructs were considered to have obtained bone ingrowth fixation. Early follow-up of patients reconstructed with porous metal augments using the inferior extended fixation surgical technique demonstrated satisfactory clinical outcomes, restoration of the center of rotation and adequate biological fixation


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_5 | Pages 19 - 19
1 Apr 2019
Zhou Y Huang Y Tang H Guo S Yang D Zhou B
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Background. Failed ingrowth and subsequent separation of revision acetabular components from the inferior hemi-pelvis constitutes a primary mode of failure in revision total hip arthroplasty (THA). Few studies have highlighted other techniques than multiple screws and an ischial flange or hook of cages to reinforce the ischiopubic fixation of the acetabular components, nor did any authors report the use of porous metal augments in the ischium and/or pubis to reinforce ischiopubic fixation of the acetabular cup. The aims of this study were to introduce the concept of extended ischiopubic fixation into the ischium and/or pubis during revision total hip arthroplasty [Fig. 2], and to determine the early clinical outcomes and the radiographic outcomes of hips revised with inferior extended fixation. Methods. Patients who underwent revision THA utilizing the surgical technique of extended ischiopubic fixation with porous metal augments secured in the ischium and/or pubis in a single institution from 2014 to 2016 were reviewed. 16 patients were included based on the criteria of minimum 24 months clinical and radiographic follow-up. No patients were lost to follow-up. The median duration of follow-up for the overall population was 37.43 months. The patients' clinical results were assessed using the Harris Hip Score (HHS), Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index and Short form (SF)-12 score and satisfaction level based on a scale with five levels at each office visit. All inpatient and outpatient records were examined for complications, including infection, intraoperative fracture, dislocation, postoperative nerve palsy, hematoma, wound complication and/or any subsequent reoperation(s). The vertical and horizontal distances of the center of rotation to the anatomic femoral head and the inclination and anteversion angle of the cup were measured on the preoperative and postoperative radiographs. All the postoperative plain radiographs were reviewed to assess the stability of the components. Results. At the most recent follow-up, 11 (68.8%) patients rated their satisfaction level as “very satisfied” and 4 (25.0%) were “satisfied.” The median HHS improved significantly and the WOMAC global score decreased significantly at the latest follow-up (? 0.001). No intraoperative or postoperative complications were identified. All constructs were considered to have obtained bone ingrowth fixation. The median vertical distance between the latest postoperative center of rotation to the anatomic center of the femoral head improved from 14.7±10.05 mm preoperatively to 6.77±9.14 mm at final follow-up (p=0.002). The median horizontal distance between the latest postoperative center of rotation to the anatomic center of femoral head improved from 6.3±12.07 mm laterally preoperatively to 2.18±6.98 mm medially at the most recent follow-up (p=0.013) postoperatively. The median acetabular cup abduction angle improved from 55.04°±10.11° preoperatively to 44.43°± 5.73° at the most recent follow-up postoperatively (p=0.001). However, there was no difference in the median cup anteversion angles preoperatively (9.15°±5.36°) to postoperatively (9.66°±3.97°) (P=0.535). Conclusions. Early follow-up of patients reconstructed with the technique of extended ischiopubic fixation with porous metal augments demonstrated satisfactory clinical outcomes, restoration of the center of rotation and adequate biological fixation. For any figures or tables, please contact the authors directly


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_5 | Pages 20 - 20
1 Apr 2019
Tang H Zhou Y Zhou B Huang Y Guo S
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Aims. Severe, superior acetabular bone defects are one of the most challenging aspects to revision total hip arthroplasty (THA). We propose a new concept of “superior extended fixation” as fixation extending superiorly 2 cm beyond the original acetabulum rim with porous metal augments, which is further classified into intracavitary and extracavitary fixation. We hypothesized that this new concept would improve the radiographic and clinical outcomes in patients with massive superior acetabular bone defects. Patients and Methods. Twenty eight revision THA patients were retrospectively reviewed who underwent reconstruction with the concept of superior extended fixation from 2014 to 2016 in our hospital. Patients were assessed using the Harris Hip Score (HHS) and the Western Ontario and McMaster Universities Osteoarthritis Index score (WOMAC). In addition, radiographs were assessed and patient reported satisfaction was collected. Results. At an average follow-up of 28 months (range 18 – 52 months), the postoperative HHS and WOMAC scores were significantly improved at the last follow-up (p < 0.001). The postoperative horizontal and vertical locations of the COR from the interteardrop line were significantly improved from the preoperative measurements (p < 0.001). One (3.6 %) patient was dissatisfied due to periprosthetic joint infection. Conclusion. Extracavitray and intracavitary superior extended fixation with porous metal augments and cementless cups are effective in reconstructing severe superior acetabular bone defects, with promising short-term clinical and radiographic outcome


The Bone & Joint Journal
Vol. 95-B, Issue 11_Supple_A | Pages 103 - 108
1 Nov 2013
Abolghasemian M Tangsataporn S Sternheim A Backstein DJ Safir OA Gross AE

The conventional method for reconstructing acetabular bone loss at revision surgery includes using structural bone allograft. The disadvantages of this technique promoted the advent of metallic but biocompatible porous implants to fill bone defects enhancing initial and long-term stability of the acetabular component. This paper presents the indications, surgical technique and the outcome of using porous metal acetabular augments for reconstructing acetabular defects. . Cite this article: Bone Joint J 2013;95-B, Supple A:103–8


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 12 | Pages 1555 - 1560
1 Dec 2009
Lingaraj K Teo YH Bergman N

We investigated the early results of modular porous metal components used in 23 acetabular reconstructions associated with major bone loss. The series included seven men and 15 women with a mean age of 67 years (38 to 81), who had undergone a mean of two previous revisions (1 to 7). Based on Paprosky’s classification, there were 17 type 3A and six type 3B defects. Pelvic discontinuity was noted in one case. Augments were used in 21 hips to support the shell and an acetabular component-cage construct was implanted in one case. At a mean follow-up of 41 months (24 to 62), 22 components remained well fixed. Two patients required rerevision of the liners for prosthetic joint instability. Clinically, the mean Harris Hip Score improved from 43.0 pre-operatively (14 to 86) to 75.7 post-operatively (53 to 100). The mean pre-operative Merle d’Aubigné score was 8.2 (3 to 15) and improved to a mean of 13.7 (11 to 18) post-operatively. These short-term results suggest that modular porous metal components are a viable option in the reconstruction of Paprosky type 3 acetabular defects. More data are needed to determine whether the system yields greater long-term success than more traditional methods, such as reconstruction cages and structural allografts


The Bone & Joint Journal
Vol. 99-B, Issue 5 | Pages 607 - 613
1 May 2017
Mäkinen TJ Abolghasemian M Watts E Fichman SG Kuzyk P Safir OA Gross AE

Aims. It may not be possible to undertake revision total hip arthroplasty (THA) in the presence of massive loss of acetabular bone stock using standard cementless hemispherical acetabular components and metal augments, as satisfactory stability cannot always be achieved. We aimed to study the outcome using a reconstruction cage and a porous metal augment in these patients. Patients and Methods. A total of 22 acetabular revisions in 19 patients were performed using a combination of a reconstruction cage and porous metal augments. The augments were used in place of structural allografts. The mean age of the patients at the time of surgery was 70 years (27 to 85) and the mean follow-up was 39 months (27 to 58). The mean number of previous THAs was 1.9 (1 to 3). All patients had segmental defects involving more than 50% of the acetabulum and seven hips had an associated pelvic discontinuity. . Results. Three failures were observed in two hips, both of which had undergone a previous resection of a tumour affecting the acetabulum. Other complications included a late arterial injury, a sciatic nerve palsy, a dislocation treated with a femoral revision, a deep infection treated with irrigation and debridement and a fracture of the greater trochanter treated conservatively. The mean Oxford Hip Score significantly increased from 13.9 (2 to 23) to 28.7 (13 to 38) (p < 0.00001). The mean vertical distance between the centre of rotation of the hip and its normal location decreased from 30 mm to 10 mm. Conclusions. Acceptable early survivorship can be achieved using this novel technique, but it may be unsuitable for use in patients who have previously undergone the resection of a tumour involving the acetabulum. Cite this article: Bone Joint J 2017;99-B:607–13


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 12 - 12
1 Mar 2010
Dunbar MJ Hennigar A Wilson D Amirault JD Reardon G Gross M
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Purpose: Porous metal technology may have significant impacts on implant fixation and long-term survival due to their high co-efficient of friction and similarity to trabecular bone in morphology and mechanical behaviour. While promising, the in vivo mechanical behaviour and micromotion at the interface has not previously been reported on. We report on the 2-year results of an RCT using radiosterometric analysis (RSA) to asses a porous metal (PM) monoblock tibial component. Method: Patients undergoing TKA were randomized to receive a either the PM (n=34) or the cemented tibial component (n=33). A standardized protocol was used for intra and post-operative factors. RSA exams were obtained postoperatively within 4 days of surgery and at 6, 12 and 24 months. One patient was excluded due to an intraoperative complication, and four others were lost to follow-up due to poor bead visibility or morbidity. Standard subjective outcome measures were applied. Results: There were no revisions in either group. The PM group exhibited two distinct migration patterns. One group stabilized immediately with similar migration to the cemented cases (0.38 vs. 0.46 p=0.4). A subset of 6 PM cases demonstrated significantly higher initial migration (mean=2.01mm, p< 0.01) but appeared stable at 2 years. In addition, 3 of the 6 high migration cases manifested independent bead subsidence. This was determined to be due to PM plate deformation. Two cemented cases were considered at risk for early failure due to aseptic loosening because of RSA migration pattern. There were no differences between groups in the subjective health outcome measures. Conclusion: A subset of PM components demonstrated high early migration followed by stabilization. It appears that some of these PM components deformed under load, most often in the posteromedial corner, perhaps as a result of malalignment or ligament imbalance. The implications of this finding are yet to be determined


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 26 - 26
1 Oct 2018
Dunbar MJ Laende E Richardson CG
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Introduction. Cementless fixation in total knee arthroplasty has been proposed to offer advantages long-term once osteointegration has occurred as there is no substrate between the implant and the bone to fail. Radiostereometric analysis (RSA) is a useful tool to study fixation, but typically focused on early migration in the first two post-operative years. Few studies have looked at 10-year RSA migration in cementless fixation and those that have contain small numbers of subjects. The objective of this study was to compare implant migration and inducible displacement between cemented and cementless TKA at 10 years and to compare the 10-year migration to the 2-year data in an effort to validate the predictive modelling of RSA. Methods. Subjects who had previously participated in RSA migration studies with 2-year follow-up were recruited to return for a long-term follow-up exam, at least 10 years from their surgery. The implants under study included two cemented designs from two manufacturers and one porous metal monoblock cementless design. At the 10-year visit, subjects had supine RSA exams to determine long-term migration as well as a loaded exam (single leg stance) to determine inducible displacement. Differences between cemented and cementless groups were evaluated with the Mann Whitney U test and Spearman's rank correlation coefficients were calculated for early and late migrations. Significance was set at p < 0.05. Results. Seventy-five subjects were available for long-term follow-up, with average time since surgery of 12 years. This cohort contained 51 women and 24 men with cemented tibial components in 53 cases (37 female) and cementless tibial components in 22 cases (14 female). At the time of surgery, the subjects were 62±7 years old with BMIs of 33±6 m/kg2 (mean±standard deviation). Median migration at the long-term follow-up was 0.6 mm (MTPM; range 0.2–2.8 mm) and was not different between the cemented and cementless groups (p = 0.9, Mann Whitney U Test). Inducible displacement at 10 years was significantly lower for the cementless implants (p<0.001, Figure 1). Migration at one, two, and 10 years did not correlate with inducible displacement at 10 years. However, migration at one year and two years did correlate with long-term migration, with the strongest correlation at two years (Spearman's rank correlation coefficient for all components = 0.74, p < 0.001, Figure 2). Conclusion. Although long-term migration was not different for cemented or cementless (porous metal monoblock) tibial components, inducible displacement at the 10-year visit was significantly lower for these cementless components, suggesting superior fixation. Additionally, long-term migration was strongly correlated to two-year migration, regardless of fixation. These findings support the predictive value of short-term migration in determining long-term fixation. For any figures or tables, please contact authors directly


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 175 - 175
1 Mar 2008
Manunta A Fadda M Fiore A Zirattu F
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Metallosis is a combined chemical and toxic reaction which, if the wear of a metal implant is large, may cause extensive reaction of synovial membrane and thus triggering the loosening. We present a case of a 72 year-old man, who underwent to a cemented unicompartimental porous metal coated knee implant because affected by rheumatoid arthritis complicated by osteonecrosis of medial femoral condyle of the knee. Four years after replacement, the patient presented symptoms included moderate swelling, pain, synovitis inability to bear full weight as well as grinding; plain radiographs shows well fixed implant and not finding of loosening of prosthesis; arthroscopy revealed the diagnosis of metallosis. The specimens of synovial tissue were prepared to observation to light and electron microscopy. Total synovialectomy and revison with total knee replacement were successful in relieving the symptoms. Arthroscopy examination revealed a posterior break of tibial component, source of the release of multiple metal beads; we observe alsogray black discoloration of hypertofic and hyperplastic synovium pannus like; metal beads were detected in the joint space soft tissue and were also embedded in the articulating surface of the tibia component. Microscopic examination shows metal debris as black aggregates and a diffuse sheet like proliferation inside histiocytes of villous membrane. Ultrastructural study demonstrate that the presence of metallic fragments, measuring less than 0.3 micron in diameter is predominantly concentrated inside the macrophage’s phagolisosomes. Delivery of large number of metal beads from implant and the release of smallest size metal debris play a pivotal role in the development of a foreign body granulomatous reaction. The failure of unicompartimental prosthesis has been accellerated by unperformed sinoviectomy during the first implant; the cells of synovial membrane are continuosly activated, by wear of implant material, to phagocitate and to secrete inflammatory response


The Bone & Joint Journal
Vol. 96-B, Issue 11_Supple_A | Pages 118 - 121
1 Nov 2014
Lachiewicz PF Watters TS

Metaphyseal bone loss is common with revision total knee replacement (RTKR). Using the Anderson Orthopaedic Research Institute (AORI) classification, type 2-B and type 3 defects usually require large metal blocks, bulk structural allograft or highly porous metal cones. Tibial and femoral trabecular metal metaphyseal cones are a unique solution for large bone defects. These cones substitute for bone loss, improve metaphyseal fixation, help correct malalignment, restore the joint line and may permit use of a shorter stem. The technique for insertion involves sculpturing of the remaining bone with a high speed burr and rasp, followed by press-fit of the cone into the metaphysis. The fixation and osteoconductive properties of the porous cone outer surface allow ingrowth and encourage long-term biological fixation. The revision knee component is then cemented into the porous cone inner surface, which provides superior fixation compared with cementing into native but deficient metaphyseal bone. The advantages of the cone compared with allograft include: technical ease, biological fixation, no resorption, and possibly a lower risk of infection. The disadvantages include: difficult extraction and relatively short-term follow-up. Several studies using cones report promising short-term results for the reconstruction of large bone defects in RTKR.

Cite this article: Bone Joint J 2014;96-B(11 Suppl A):118–21.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_8 | Pages 29 - 29
1 May 2019
Trousdale R
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Advantages of cones in revision TKA

Reliable, Durable, Easy to do, Solves major problems (bone loss, fixation)

Allograft concerns

Availability, Disease transmission, Preparation difficulties, Long-term fixation/incorporation


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_8 | Pages 30 - 30
1 May 2019
Sculco T
Full Access

Bone loss in total knee replacement has different configurations and most condylar and plateau deficits are well managed with prosthetic augmentation. Cones are rarely, if ever, necessary for these deficits and when entire femoral condyles are absent distal segmental replacement has worked well. In the setting of severe intramedullary bone loss on the tibial or femoral side cones may be used to support deficit bone. This is the one indication for the use of cones.

The negative side of cones is that additional bone may be removed to fit a cone adequately. Many of the lesser areas of bone deficiency can be managed by the use of larger diameter stems for fixation. In a paper from Sandford et al. from the Vancouver group allograft results at 5 −10 year follow up had a similar success rate to cones. Rohl in a paper looking at cones and hybrid stems for bone loss in revision TKR found no difference in results at 3.5 years.

Cones cost $4,000–6,000 each and their utilization has been increasing greatly. At Hospital for Special Surgery in 2015 18 cones were used, this has increased to over 150 in 2017 at a cost of $800,000. The overutilization of cones adds considerably to the cost of a revision procedure. Cones have a place in revision TKR for bone loss but it is limited and they should be used in the most extreme cases where bone augmentation is required for structural stability.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_12 | Pages 47 - 47
1 Jul 2014
Backstein D
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Restoration of bone loss is a major challenge of revision TKA surgery. It is critical to achieve of a stable construct to support implants and achieve successful results. Major bone defects of the femoral and/or tibia (AORI type IIB/III) have been reconstructed using impaction grafting, structural allografts or tumor prostheses. The major concerns with structural allograft are graft resorption, mechanical failure, tissue availability, disease transmission, considerable surgical skill required and prolonged operative time. Porous tantalum metaphyseal cones, are becoming the established method of choice to correct large bone defects with several recent studies demonstrating promising results. The high coefficient of friction of these implants provides structural support for femoral and tibial components. The high degree of porosity has excellent potential for bone ingrowth and long-term biologic fixation. Several published series, although with relatively small cohorts of patients, have reported good short-term results with trabecular metal cones for major femoral and tibial bony defects in revision TKA. In a recent study, 16 femoral and 17 tibial cones were reviewed at an average follow up of 33 months (range, 13 to 73 months) the mean Knee Society Score improved from 42 pre-operatively to 83 at last follow up with an improvement of the functional score from an average of 34 to 66 (p<0.0001). Radiological follow up revealed no evidence of loosening or migration of the constructs. No evidence of complications were noted in correlation with the use of trabecular metal cones.