Many recent knee prostheses are designed aiming to the physiological knee kinematics on tibiofemoral joint, which means the femoral rollback and medial pivot motion. However, there have been few studies how to design a patellar component. Since patella and tibia are connected by a patellar tendon, tibiofemoral and patellofemoral motion or contact forces might affect each other. In this study, we aimed to discuss the optimal design of patellar component and simulated the knee flexion using four types of patellar shape during deep knee flexion. Our simulation model calculates the position/orientation, contact points and contact forces by inputting knee flexion angle, muscle forces and external forces. It can be separated into patellofemoral and tibiofemoral joints. On each joint, calculations are performed using the condition of point contact and force/moment equilibrium. First, patellofemoral was calculated and output patellar tendon force, and tibiofemoral was calculated with patellar tendon force as external force. Then patellofemoral was calculated again, and the calculation was repeated until the position/orientation of tibia converged. We tried four types of patellar shape, circular dome, cylinder, plate and anatomical. Femoral and tibial surfaces are created from Scorpio NRG PS (Stryker Co.). Condition of knee flexion was passive, with constant muscle forces and varying external force acting on tibia. Knee flexion angle was from 80 to 150 degrees. As a result, the internal rotation of tibia varied much by using anatomical or plate patella than dome or cylinder shape. Although patellar contact force did not change much, tibial contact balances were better on dome and cylinder patella and the medial contact forces were larger than lateral on anatomical and plate patella. Thus, the results could be divided into two types, dome/cylinder and plate/anatomical. It might be caused by the variations of patellar rotation angle were large on anatomical and plate patella, though patellar tilt angles were similar in all the cases. We have already reported that the anatomical shape of patella would contact in good medial-lateral balance when tibia moved physiologically, therefore we have predicted the anatomical patella might facilitate the physiological tibiofemoral motion. However, the results were not as we predicted. Actually our previous and this study are not in the same condition; we used a posterior-stabilized type of prosthesis, and the post and cam mechanism could not make the femur roll back during deep knee flexion. It might be better to choose dome or cylinder patella to obtain the stability of tibiofemoral joint, and to choose anatomical or plate to the mobility

Aims

The aim of this study was to evaluate cartilaginous patellotrochlear congruence and patellofemoral alignment parameters after deepening trochleoplasty in severe trochlear dysplasia.

Aim. Nail patella syndrome (NPS) is a skeletal dysplasia with patellofemoral dysfunction as a key symptom. We present the first in-depth radiological evaluation of the knee in a large series of NPS patients and describe the typical malformations. Patients and Methods. Conventional radiological examination of 95 skeletally mature patients with NPS was performed. Patellar morphology was classified according to the Wiberg classification as modified by Baumgartl and Ficat criteria, and trochlear shape was classified according to the Dejour classification. Results. Patellar aplasia was present in 4/90 (4%), and patellar hypoplasia in 77/90 (86%) of patients. The prevailing patellar shapes were type III, type IV and Hunter’s cap. No patellar shape genotype-phenotype association could be found. The malformations of the distal femur comprised shortening of the lateral femoral condyle in 46 out of 84 patients (55%), with a prominent anterior surface of the lateral femoral condyle in 47 out of 84 patients (56%) and a flat anterior surface of the medial femoral condyle in 78 out of 85 patients (92%). The trochlea was type A1 according to the Dejour classification in 79 out of 85 patients (93%). . Conclusion. An easily recognisable characteristic quartet of malformations consisting of patellar aplasiaor hypoplasia and the malformations of the distal femur was found in 22 out of 81 patients (27%), with the majority displaying at least three malformations. Take home message: The distinct malformations of the knee in nail patella syndrome are easily recognisable on conventional radiographs and lead to the correct interpretation of the aberrant morphology which is essential in the treatment of these patellofemoral disorders. Cite this article: Bone Joint J 2016;98-B:483–9

Objectives. It has been hypothesized that patellofemoral pain, a common knee condition in adolescents and young adults, may be a precursor of degenerative joint changes and may ultimately lead to patellofemoral osteoarthritis. Since both conditions share several mechanical disease characteristics, such as altered contact area between the femur and patella and increased joint stress, we investigated whether these conditions share similar and different shape characteristics of the patella compared with normal controls. Methods. This cross-sectional study compared three different study populations: 32 patellofemoral pain subjects (mean age, 32 years (22 to 45); 72% female); 56 isolated radiological patellofemoral osteoarthritis subjects (mean age, 54 years (44 to 58); 89% female); and 80 healthy control subjects (mean age, 52 years (44 to 58); 74% female). Measurements included questionnaires, and lateral and skyline radiographs of the knee. Two separate 30-point 2D statistical shape models of the patella were created from the lateral and skyline radiographs. A general linear model was used to test for differences in standardized shape modes (a specific shape variant of the patella) between patellofemoral osteoarthritis, patellofemoral pain, and controls, using Bonferroni correction and adjustment for body mass index and gender. Results. Five shape modes showed statistically significant differences between groups: skyline modes 1 (p < 0.001), 8 (p = 0.004), and 10 (p < 0.001); and lateral modes 5 (p = 0.002) and 7 (p = 0.002). Skyline mode 8 and lateral mode 5 were similar for patellofemoral osteoarthritis and patellofemoral pain populations, while being statistically significant different from the control group. Conclusion. Our results indicate that patellofemoral pain and patellofemoral osteoarthritis share similar shape characteristics, which are different from control subjects. These findings support the proposed continuum disease model of patellofemoral pain predisposing to the development of patellofemoral osteoarthritis. Cite this article: J. F. A. Eijkenboom, J. H. Waarsing, E. H. G. Oei, S. M. A. Bierma-Zeinstra, M. van Middelkoop. Is patellofemoral pain a precursor to osteoarthritis? Patellofemoral osteoarthritis and patellofemoral pain patients share aberrant patellar shape compared with healthy controls. Bone Joint Res 2018;7:541–547. DOI: 10.1302/2046-3758.79.BJR-2018-0112.R1

The various disorders of the patellofemoral joint, from pain syndrome to maltracking and arthritis, form a significant subset of knee disorders (Callaghan and Selfe 2007). Several studies have shown significant geography and gender based variation in incidence rates of these disorders and of osteoarthritis in general (Woolf 2003). A number of previous studies have examined patellar shape in this context, focusing primarily on the use of 2D measurements of bony geometry to classify patellar shapes and identify high-risk groups (Baumgartl 1964; Ficat 1970). Recent developments in imaging and statistical analysis have enabled a more sophisticated approach, characterised by statistical shape models which account for three dimensional shape differences (Bryan 2008). Incorporating soft tissue data into these analyses, however, has been a challenge due to factors including the necessity of multi-modality images, absence of repeatable landmarks, and complexity of the surfaces involved. We present here a novel method which has potential to significantly improve analysis of soft tissue geometry in joints. It is built using Arthron, a UCD-developed biomechanics analysis software package. The shape modelling process consists of three phases: pre-processing, consistent surface parameterization, and statistical shape analysis. The pre-processing phase consists of several mesh processing operations that prepare the input surfaces for shape modelling. Consistent surface parameterizations are implemented using the minimum description length (MDL) correspondence method (Davies 2002) [Fig. 1]. The statistical shape analysis phase involves the reporting and visualization of geometric variation at the input surface. An algorithm was developed to measure the cartilage thickness at each node on the patellar surface mesh. The initial step in this process was to calculate surface normal vectors at each point. These vectors were then projected through the cartilage surface model in order to calculate the thickness [Fig. 2]. The Matlab software was used to aggregate all cartilage thickness values in a given subgroup and after being normalised for the average patellar centroid size for the subgroup, these thicknesses were visualised on the average shape. Pilot study data consisted of 19 Caucasian (7 female, 12 male) and 13 Japanese (7 female, 6 male) subjects. These data originated from studies performed by DePuy Orthopaedics Inc. Initial results show ethnicity effects in cartilage thickness to be more significant than gender effects [Fig. 3]. After correcting for patellar centroid size, male subjects display 9% greater average thickness than female subjects, while Caucasian subjects display 17% greater average thickness than Asian subjects. Areas of statistically significant differences (t < 0.05) were found to coincide with expected areas of patellofemoral contact through the flexion cycle, showing the potential for the thickness differential to impact upon patellar kinematics. Principal component analysis of the thickness distributions gives more detailed information about modes of variation. With further development, this method has potential to enable sophisticated analysis of localised variation in soft tissue geometry, thereby improving understanding of the impact of joint geometry on disease formation

Background. Patellar instability is a complex, multi-factorial disorder. Radiological assessment is regarded as an important part of the management of this population. The purpose of this study was to determine the intra- and inter-rater reliability of common radiological measurements used to evaluate patellar instability. Methods. One hundred and fifty x-rays from 51 individuals were reviewed by five reviewers: two orthopaedic trainees, a radiological trainee, a consultant radiologist and an orthopaedic physiotherapist. Radiological measurements assessed included patellar shape, sulcus angle, congruence angle, lateral patellofemoral angle (LPA), lateral patellar displacement (LPD), lateral displacement measurement (LDM), boss height, and patellar height ratios (Caton-Deschamps, Blackburne-Peel, Insall-Salvati). All assessors were provided with a summary document outlining the method of assessing each measurement. Bland-Altman analyses were adopted to assess intra- and inter-rater reliability. Results. The results indicated generally low measurement error on intra-rater reliability assessment, particularly for LPD (within-subject variance 0.7mm to 3.7mm), LDM (0.7mm to 3.5mm) and boss height (0.4mm to 1.6mm) for all assessors. There was greater measurement error for the calculation of sulcus angle (0.7° to 10.6°), congruence angle (0.8° to 18.4°) and LPA (0.8° to 16.5°). Whilst the inter-rater reliability between assessors indicated a low mean difference for assessments of patellar height measurements (0.0° to 0.6°), there was greater variability for LPA (0.1° to 3.6°), LPD (0.2mm to 4.6mm) and LDM (0.1mm to 4.0mm), with wide 95% limits of agreement for all measurements indicated poor precision. Conclusions. Many of the standard measurements used to assess the patellofemoral joint on plain radiographs have poor precision. Intra-rater reliability may be related to experience but it seems likely that to achieve good inter-rater reliability, specific training may be required to calibrate observers. More formal training in the technique of radiological measurement for those who were inexperienced might have improved the inter-rater reliability

1 . Current theories of the etiology of chondromalacia patellae do not explain satisfactorily either its great frequency or its common site of origin on the medial patellar facet. 2. The etiology can be more logically explained by the presence of a ridge on the upper anterior border of the cartilage of the medial femoral condyle, in most knees. This ridge, consisting of cartilage, or cartilage and bone, varies considerably in height and, in normal knee joint movement, causes considerable friction on the medial patellar facet. 3. The degenerative changes were found to be greater in the presence of the larger ridges, and–because of longer wear and tear–in the older patients. 4. This study indicates that chondromalacia was more severe in women than in men, and in patients overweight. Although the activity of the individual and the power of the quadriceps mechanism must play an extremely important part in this condition, it was not possible to assess this. 5. Two factors previously considered to be important in the etiology of this condition, namely, the length of the patellar tendon and Wiberg's Type III patellar shape, have not been confirmed in this study. 6. Resulting from the present investigation certain precautions are suggested in rehabilitation after operations on the knee, and a surgical method for discouraging the progress of this common, and sometimes disabling, condition has been devised

Introduction. We have been re-evaluating patellofemoral alignment after total knee arthroplasty (TKA) by using a weight- bearing axial radiographic view after detecting patellar maltracking (lateral tilt > 5° or lateral subluxation > 5 mm) on standard non-weight-bearing axial radiographs. However, it is unclear whether the patellar component shape affects this evaluation method. Therefore, we compared 2 differently shaped components on weight-bearing axial radiographs. Methods. From 2004 to 2013, 408 TKAs were performed with the same type of posterior-stabilized total knee implant at our hospital. All patellae were resurfaced with an all-polyethylene, three-pegged component to restore original thickness. Regarding patellar component type, an 8-mm domed component was used when the patella was so thin that a 10-mm bone cut could not be performed. Otherwise, a 10-mm medialized patellar component was selected. Twenty-five knees of 25 patients, in whom patellar maltracking was noted on standard axial radiographs at the latest follow-up, were included in this study. Knees were divided into 2 groups: 15 knees received a medialized patella (group M) while 10 received a domed patella (group D). Weight-bearing axial radiographs with patients in the semi-squatting position were recorded with the method of Baldini et al. Patellar alignment (tilt and subluxation) was measured according to the method described by Gomes et al. using both standard and weight-bearing axial views. Results. Patients’ demographic data, such as age at surgery, sex, and disease were similar for both groups. The average follow-up period was significantly longer in group D than group M (5.4 years vs. 2.5 years, respectively; p = 0.0045, Mann- Whitney U-test). The lateral tilt angle decreased significantly (p < 0.0001, paired t-test) from 6.5° ± 2.8° to 1.0° ± 1.2° with weight bearing in group M. However, this parameter in group D changed from 6.7° ± 2.7° to 4.7° ± 3.0° with weight bearing; the difference was not significant. Lateral subluxation also decreased significantly (p < 0.0001, paired t-test) from 5.1 mm ± 2.4 mm to 2.5 mm ± 1.4 mm with weight bearing in group M. However, that in group D changed from 2.8 mm ± 2.7 mm to 2.4 mm ± 2.8 mm with weight bearing, and the difference was not significant. On weight-bearing views, patellar maltracking was noted in 4 knees in group D but no knees in group M. The difference was significant (p = 0.017, Fisher's exact test). One of the 21 patients with adequate patellar tracking (4.8%) and 1 of 4 patients with maltracking (25%) complained of mild anterior knee pain. Discussion. Patellar tracking on axial radiographic views improved better in group M than in group D with weight bearing. The patellofemoral contact area was maintained with a domed patella despite tilting, but not with a medialized patella. Our results indicate that the shape difference affected the degree of radiographic improvement. Thus, the weight-bearing axial radiographic view devised by Baldini et al. is useful for evaluating patellofemoral alignment after TKA, but the shape of the patellar component should be considered for result interpretation

Summary Statement. A large proportion of knee arthroplasty patients are dissatisfied with their replacement. Significant differences exist between preoperative, postoperative and normal kinematics. A better understanding of the inter-relationships between kinematics, shape and prosthesis placement could lead to improved quality of life. Introduction. Knee kinematics are altered by total knee arthroplasty (TKA) both intentionally and unintentionally. Knowledge of how and why kinematics change may improve patient outcome and satisfaction through improved implant design, implant placement or rehabilitation. Comparing preoperative to postoperative kinematics and shape of the natural and replaced joint will allow an investigation of the inter-relationships between knee shape, prosthesis placement, knee kinematics and quality of life. Patients & Methods. Using a sequential-biplanar radiographic protocol that allowed imaging the preoperative and postoperative patellofemoral (PF) and tibiofemoral (TF) joints under weightbearing throughout the range of motion, we imaged and compared the 6 degree-of-freedom PF and TF kinematics of 9 pre-TKA subjects to those of 15 post-TKA subjects (Zimmer NexGen Legacy Posterior Stabilised Gender Solutions (GS) components). Using a novel computed tomography (CT) protocol, we obtained the femoral, tibial and patellar knee shapes, plus component placement after TKA. The same 9 pre-TKA subjects have now been re-imaged a minimum of one year postoperatively (DePuy Sigma Mobile Bearing cruciate-sacrificing components) to determine their changes in knee geometry and kinematics; full analysis is in progress. Results. Clear, statistically significant differences were seen between the kinematics of the pre-TKA and post-TKA groups. For the TF joint, the tibia was more posterior and inferior in the post-TKA group compared to the pre-TKA group (max 20 mm and 15 mm, respectively) (p<0.001). Subjects had neutral alignment in the post-TKA group compared to varus alignment (max 9°) in the pre-TKA group (p<0.001). For the PF joint, the patella was shifted more posteriorly and less laterally postoperatively and was tilted neutrally compared to laterally (p<0.001). Our preliminary analysis of the matched preop-postop subjects likewise shows a more posterior and inferior tibia and neutral versus valgus alignment. Greater tibial rotations were seen postoperatively due to the mobile bearing. The patella was more posterior and less lateral postoperatively, as seen with the two groups. Discussion/Conclusion. The kinematic differences seen are likely due to a combination of surgical, implant and patient factors. Both groups showed differences from normal kinematics, based on previous studies in the literature. In the future, by comparing the preoperative and postoperative kinematics, shape and quality of life for the same subjects (i.e. the 9 pre-TKA subjects in this study), and analyzing the interrelationships amongst these, we aim to determine if a different implant shape or different component positioning could create more normal kinematics, resulting in a better clinical outcome

Patellar instability most frequently presents during adolescence. Congenital and infantile dislocation of the patella is a distinct entity from adolescent instability and measurable abnormalities may be present at birth. In the normal patellofemoral joint an increase in quadriceps angle and patellar height are matched by an increase in trochlear depth as the joint matures. Adolescent instability may herald a lifelong condition leading to chronic disability and arthritis.

Restoring normal anatomy by trochleoplasty, tibial tubercle transfer or medial patellofemoral ligament (MPFL) reconstruction in the young adult prevents further instability. Although these techniques are proven in the young adult, they may cause growth arrest and deformity where the physis is open. A vigorous non-operative strategy may permit delay of surgery until growth is complete. Where non-operative treatment has failed a modified MPFL reconstruction may be performed to maintain stability until physeal closure permits anatomical reconstruction. If significant growth remains an extraosseous reconstruction of the MPFL may impart the lowest risk to the physis. If minor growth remains image intensifier guided placement of femoral intraosseous fixation may impart a small, but acceptable, risk to the physis.

This paper presents and discusses the literature relating to adolescent instability and provides a framework for management of these patients.

Cite this article: Bone Joint J 2017;99-B:159–70.

We retrospectively analysed the MR scans of 25 patients with patellofemoral dysplasia and ten control subjects, to assess whether there was any change in the morphology of the patella along its vertical length. Ratios were calculated comparing the size of the cartilaginous and subchondral osseous surfaces of the lateral and medial facets. We also classified the morphology using the scoring systems of Baumgartl and Wiberg. There were 18 females and seven males with a mean age of 20.2 years (10 to 29) with dysplasia and two females and eight males with a mean age of 20.4 years (10 to 29) in the control group.

In the patient group there was a significant difference in morphology from proximal to distal for the cartilaginous (Analysis of variance (ANOVA) p = 0.004) and subchondral osseous surfaces (ANOVA, p = 0.002). In the control group there was no significant difference for either the cartilaginous (ANOVA, p = 0.391) or the subchondral osseous surface (ANOVA, p = 0.526).

Our study has shown that in the dysplastic patellofemoral articulation the medial facet of the patella becomes smaller in relation to the lateral facet from proximal to distal. MRI is needed to define clearly the cartilaginous and osseous morphology of the patella before surgery is considered for patients with patellofemoral dysplasia.

Patella subluxation assessed on dynamic MRI has previously been shown to be associated with anterior knee pain. In this MRI study of 60 patients we investigated the relationship between subluxation and multiple bony, cartilaginous and soft-tissue factors that might predispose to subluxation using discriminant function analysis.

Patella engagement (% of patella cartilage overlapping with trochlea cartilage) had the strongest relationship with subluxation. Patellae with > 30% engagement tended not to sublux; those with < 30% tended to sublux. Other factors that were associated with subluxation included the tibial tubercle-trochlea notch distance, vastus medialis obliquus distance from patella, patella alta, and the bony and cartilaginous sulcus angles in the superior part of the trochlea. No relationship was found between subluxation and sulcus angles for cartilage and bone in the middle and lower part of the trochlea, cartilage thicknesses and Wiberg classification of the patella.

This study indicates that patella engagement is a key factor associated with patellar subluxation. This suggests that in patients with anterior knee pain with subluxation, resistant to conservative management, surgery directed towards improving patella engagement should be considered. A clinical trial is necessary to test this hypothesis.