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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 236 - 236
1 Sep 2012
Roche J Joss B DeSteiger R Miller L Nivbrant B Wood D
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There is ongoing debate on the benefits of fixed versus mobile bearing Unicompartmental Knee Replacement (UKR). We report the results from a randomised controlled trial comparing fixed and mobile bearing of the same UKR prosthesis. Forty patients were randomized to receive identical femoral components and either a fixed or mobile bearing tibial component. At 6.5 years follow-up 37% of the mobile bearing design had been revised and 14% for the fixed bearing design. The main reasons for revision were pain and loosening. These results were compared with data from The Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) that show a cumulative percent revision of 24.2% for the mobile bearing Preservation UKR at 6.5 years. All locally explanted mobile bearings were examined microscopically, and 83% demonstrated significant backside wear. Constraint on the undersurface of the bearing coupled with a congruent upper surface may have contributed to the excessive revision rate. This is the first randomised controlled trial examining mobile and fixed variations of the same UKR prosthesis and shows this design of UKR with the mobile bearing has an unacceptably high revision rate and patients with this knee design should be closely monitored


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 141 - 141
1 Jan 2016
Ryu K Suzuki T Iriuchishima T Kojima K Saito S Ishii T Nagaoka M Tokuhashi Y
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Objective. Mobile bearing unicompartmental knee arthroplasty (UKA) is an effective and safe treatment for osteoarthritis of the medial compartment. However, mobile-bearing UKA needs accurate ligament balancing of flexion and extension gaps to prevent dislocation of the mobile meniscal bearing. Instability can lead to dislocation of the insert. The phase 3 instruments of the Oxford UKA use a balancing technique for the flexion gap (90° of flexion) and extension gap (20° of flexion), thereby focusing attention on satisfactory soft tissue balancing. With this technique, spacers are used to balance the flexion and extension gap. However, gap kinematics in another flexion angle of mobile-bearing UKA is unclear. We developed UKA tensor for mobile-bearing UKA and we assessed the accurate gap kinematics of UKA. Materials and Methods. Between 2012 and 2013, The Phase 3 Oxford Partial Knee UKA (Biomet Inc., Warsaw, IN) were carried out in 48 patients (71 knees) for unicompartmental knee osteoarthritis or spontaneous osteonecrosis of the medial compartment. The mean age of patients at surgery was 71.6 years and the mean follow-up period was 1.7 years. The mean preoperative coronal plane alignment was 7.4° in varus. The indications for UKA included disabling knee pain with medial compartment disease; intact ACL and collateral ligaments; preoperative contracture of less than 15°; and preoperative deformity of <15°. Each surgery was performed by using different spacer block with 1-mm increments and the meniscal bearing lift-off tests according to surgical technique. We developed newly tensor for mobile bearing UKA which designed to permit surgeons to measure multiple range of the joint medial compartment/joint component gap, while applying a constant joint distraction force (Figure 1). We assessed the intra-operative joint gap measurements at 0, 20, 60, 90 and 120 of flexion with 100N, 125N and 150N of joint distraction forces. Results. The gaps measured were 0°: 8.6 ± 1.6, 20°: 9.2 ± 1.4, 60°: 9.6 ± 1.2, 90°: 11.1 ± 1.3, 120°: 11.6 ± 1.8 in 100 N, 0°: 9.7 ± 1.7, 20°: 11.2 ± 1.3, 60°: 11.4 ± 1.3, 90°: 11.9 ± 1.5, 120°: 10.4 ± 1.6 in 125 N, 0°: 11.3±1.4, 20°: 11.8 ± 1.3, 60°: 11.1 ± 1.2, 90°: 12.5 ± 1.3, 120°: 11.9 ± 1.6 in 150N (Figure 2). There was a significant difference between full extension to extension (20° of flexion) and flexion (90° of flexion) to full flexion (120° of flexion). Conclusion. Mobile bearing UKA instrumentation using a balancing technique by spacer block for the flexion gap (90° of flexion) and extension gap (20° of flexion), full extension gap was significantly smaller than extension gap and flexion gap was significantly smaller than full flexion gap in 100N, 125N and 150N of joint distraction forces


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 16 - 16
1 Jan 2004
Price A Short A Kellett C Rees J Pandit H Dodd C McLardy-Smith P Gundle R Murray D
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The aim of the study was to measure in-vivo the 10-year linear and volumetric polyethylene wear of a fully congruent mobile bearing unicompartmental knee arthroplasty (OUKA). We studied six OUKA’s that had all been implanted 10 years previously. Each patient was examined in even double leg stance at a range of knee flexion angles, in a calibration cage. A stereo pair of X-ray films was acquired for each patient at 0°, 15° and 30° of flexion. The films were analysed using an RSA style calibration and a CAD model silhouette-fitting technique. The position and orientation of each femoral and tibial component was found relative to each other and the bearing position inferred. Penetration of the femoral component into the original volume of the bearing was our estimate of linear wear. The volumetric wear is calculated from the measured linear wear and the known surface area of the bearing. In addition eight control patients were examined less than 3 weeks post-operation where no wear would be expected.and 30We studied seven OUKA’s that had all been implanted at least 10 years previously. A stereo pair of X-ray films was acquired for each patient at 0 Results: The control group showed no measured wear. The seven OUKA’s had an average maximum depth of linear penetration of 0.40 mm at a mean follow-up of 10.9 years. The linear wear rate was 0.033 mm/year. The volumetric material loss was 79.8 mm3. If a steady gradual material loss is assumed, 8 mm3 of UHMWPE was lost per year. Polyethylene particulate wear debris continues to be implicated in the aetiology of component loosening and implant failure knee following arthroplasty. The OUKA employs a spherical femoral component and a fully congruous meniscal bearing to increase contact area and theoretically reduce the potential for polyethylene wear. The results from this in-vivo study confirm that the device has low 10-year linear and volumetric wear in clinical practice. This may protect the device from component loosening in the long term


Bone & Joint Research
Vol. 9, Issue 6 | Pages 272 - 278
1 Jun 2020
Tapasvi S Shekhar A Patil S Pandit H

Aims

The mobile bearing Oxford unicompartmental knee arthroplasty (OUKA) is recommended to be performed with the leg in the hanging leg (HL) position, and the thigh placed in a stirrup. This comparative cadaveric study assesses implant positioning and intraoperative kinematics of OUKA implanted either in the HL position or in the supine leg (SL) position.

Methods

A total of 16 fresh-frozen knees in eight human cadavers, without macroscopic anatomical defects, were selected. The knees from each cadaver were randomized to have the OUKA implanted in the HL or SL position.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 27 - 27
1 Mar 2012
Pandit H Jenkins C Weston-Simons S Ferguson J Popat BM Gibbons M Price A Gill H Dodd C Murray D
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Introduction

Kozinn and Scott have made recommendations about contra-indications for unicompartmental knee replacement (UKR). They suggest that patients younger than 60, weight > 82 kilograms, patients with exposed bone in patella-femoral compartment or patients who are physically active/perform heavy labour should not be offered a UKR. In addition, chondrocalcinosis is a contra-indication. These strict selection criteria are based on the experience with fixed bearing UKAs and are more intuitive than evidence based. The Oxford UKR has a fully congruous mobile bearing and has been shown to have minimal wear. Over the past 25 years, the Oxford Group has followed a standardised protocol for patient selection for UKR. We ignore patella-femoral joint pathology, chondrocalcinosis, patient's age, weight and activity level when deciding the suitability for UKR.

Methods

Using the standardised indications, more than 1100 Oxford UKRs have been performed to date over the last 10 years. These patients are assessed pre-operatively and at regular intervals post-operatively in a dedicated research clinic. We present the results of these consecutive cases. Patients were classified into two groups: group I (satisfy Kozinn-Scott recommendations) and group II (outside recommendations).


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 54 - 54
1 Jan 2017
Etani Y
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UKA with mobile bearing is a one of the treatment of medial osteoarthritis. However, some reports refer to the risk of dislocation of the mobile bearing. Past reports pointed out that medial gap might be enlarged in deep flexion position (over 120 degrees), and says that it will lead to instability of the mobile bearing. The purpose of this study is to research the risk factors of enlargement of medial gap in deep flexion position.

We performed 81 UKAs with mobile bearing system from November 2013 to December 2015, and could evaluate 41 knees. This study of 41 knees included 9 males and 32 females, with average operation age of 75.4years(63–89years). The diagnosis was osteoarthritis in 39 knees and osteonecrosis in 2 knees. The UKA(Oxford partial knee microplasty, Biomet, Warsaw, IN) was used in all cases. We performed distal femur and proximal tibia osteotomy using CT-Free navigation system(Stryker Navigation System II/precision Knee Navigation ver4.0). And we inserted femoral and tibial trial component, then we placed an UKA tensioner on the medial component of the knee. Using tensioner under 30 lbs, we measured joint medial gap at 0,20,45,90,130(deep flexion) degrees. When we compared medial gap at 90 degrees position with at 130 degrees, we defined it as ‘instability group’ if there was gap enlargement more than 1mm, and defined it as ‘stability group’ if there wasn't.

We compared this two groups with regard to age, BMI, femoro-tibial angle (FTA), the diameter of anterior cruciate ligament (ACL), tibial angle and tibial posterior slope angle of the implant. We evaluated preoperative and postoperative FTA by weightbearing long leg antero-posterior alignment view X-rays. We measured ACL diameter at its condyle level in coronal view of MRI. Also we evaluated tibial component implantation angle by postoperative CT using 3D template system. These measurement were analyzed statistically using t test.

The stability group contained 26 knees, and the instability group contained 15 knees. Compared with the stability group, the instability group indicated higher FTA (p=0.001). Between 20 and 90 degrees flexion position, there was no change of medial gap.

Dislocation of the mobile bearing is one of the complications of UKA and it will need re-operation. It is said to be caused by impingement of the bearing and osteophyte of femur. However, some reports said that dislocation was happened when the knee was flexed deeply or twisted, and there was no impingement. We think it may means that dislocation could be caused by medial gap enlargement.

This study indicates that higher FTA could be risk factor of dislocation of mobile bearing. It is important to evaluate preoperatively FTA by X-ray.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 11 | Pages 1493 - 1497
1 Nov 2005
Price AJ Short A Kellett C Beard D Gill H Pandit H Dodd CAF Murray DW

Polyethylene particulate wear debris continues to be implicated in the aetiology of aseptic loosening following knee arthroplasty. The Oxford unicompartmental knee arthroplasty employs a spherical femoral component and a fully congruous meniscal bearing to increase contact area and theoretically reduce the potential for polyethylene wear. This study measures the in vivo ten-year linear wear of the device, using a roentgenstereophotogrammetric technique.

In this in vivo study, seven medial Oxford unicompartmental prostheses, which had been implanted ten years previously were studied. Stereo pairs of radiographs were acquired for each patient and the films were analysed using a roentgen stereophotogrammetric analysis calibration and a computer-aided design model silhouette-fitting technique. Penetration of the femoral component into the original volume of the bearing was our estimate of linear wear. In addition, eight control patients were examined less than three weeks post-insertion of an Oxford prosthesis, where no wear would be expected. The control group showed no measured wear and suggested a system accuracy of 0.1 mm. At ten years, the mean linear wear rate was 0.02 mm/year.

The results from this in vivo study confirm that the device has low ten-year linear wear in clinical practice. This may offer the device a survival advantage in the long term.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 25 - 25
1 Mar 2012
Pandit H Jenkins C Gill H Beard D Price A Dodd C Murray D
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Introduction

The results of the mobile bearing Oxford unicompartmental knee replacement (UKR) in the lateral compartment have been disappointing with a five year survival of 82%. Therefore, it is recommended that mobile bearings should not be used for lateral UKR. This low survivorship is primarily due to high dislocation rate, all occurring in the first year. A detailed analysis of the causes of bearing dislocation confirmed the elevated lateral tibial joint line to be a contributory factor. A new surgical technique was therefore introduced in which care was taken neither to remove too much bone from distal femur nor to over tighten the knee and thus ensure that the tibial joint line was not elevated. Other modifications to the technique were also introduced including use of a domed tibial component.

Aim

The aim of this study is to compare the outcome of these iterations: the original series [series I], Series II with improved surgical technique and the domed tibial component [Series III].


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 19 - 19
1 Jan 2011
Pandit H Jenkins C Beard D Gill H Price A Dodd C Murray D
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The results of mobile bearing Oxford unicompartmental knee replacement (UKR) in the lateral compartment have been disappointing (five-year survival: 82%). Therefore, it is recommended that mobile bearings should not be used for lateral UKR. This low survivorship is primarily due to a high dislocation rate. A detailed analysis confirmed the elevated lateral tibial joint line to be a contributory factor to bearing dislocation. A new surgical technique was therefore introduced in which care was taken neither to remove too much bone from the distal femur nor to over tighten the knee and therefore ensure that the tibial joint line was not elevated. Other modifications included use of a domed tibial component.

The aim of this study is to compare the outcome of these iterations: the original series (series I), those with improved surgical technique (series II) and the domed tibial component (series III). The primary outcome measure was bearing dislocation at one year. One year was chosen as all the dislocations in the first series occurred within a year. In the original series (n=53), implanted using a standard open approach, there were six dislocations in the first year, the average flexion 110°, and 95% had no/mild pain on activity. In the second series (n=65), there were 3 dislocations, the average flexion was 117°, and 80% had no/mild pain on activity.

In the third series with the modified technique and a convex domed tibial plateau, there was one dislocation, average flexion was 125° and 94% had no/mild pain on activity. At four years the cumulative primary dislocation rates were 10%, 5% and 0% respectively, and were significantly different (p=0.04).

The improved surgical technique and implant design has reduced dislocation rate to an acceptable level so a mobile bearing can now be recommended for lateral UKR.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 412 - 412
1 Sep 2009
Pandit H Jenkins C Gill H Beard D Marks B Price A Dodd C Murray D
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Introduction: The results of the mobile bearing Oxford unicompartmental knee replacement (UKR) in the lateral compartment have been disappointing with a five year survival of 82%. Therefore, it is recommended that mobile bearings should not be used for lateral UKR. This low survivorship is primarily due to high dislocation rate, all occurring in the first year. A detailed analysis of the causes of bearing dislocation confirmed the elevated lateral tibial joint line to be a contributory factor. A new surgical technique was therefore introduced in which care was taken neither to remove too much bone from the distal femur nor to over tighten the knee and therefore ensure that the tibial joint line was not elevated. Other modifications to the technique were also introduced including use of a domed tibial component.

Aim: The aim of this study is to compare the outcome of these iterations: the original series [series I], Series II with improved surgical technique and the domed tibial component [Series III].

Method: The primary assessment of outcome was bearing dislocation at one year. One year was chosen as all the dislocations in the first series occurred within a year. In series I, there were 53 knees, in series II 65 knees and in series III 60 knees, all with a minimum of one year follow up.

Results: In series I, there were 6 bearing dislocations (11%) and the average range of movement (ROM) was 110°. In the second series, there were 2 dislocations (3%) and the average ROM was 118°. In the third series, there were no primary dislocations and the average ROM was 125°.

Conclusions: The improved surgical technique and implant design has reduced the dislocation rate to an acceptable level so a mobile bearing can now be recommended for lateral UKR.


Bone & Joint Research
Vol. 8, Issue 11 | Pages 535 - 543
1 Nov 2019
Mohammad HR Campi S Kennedy JA Judge A Murray DW Mellon SJ

Objectives

The aim of this study was to determine the polyethylene wear rate of Phase 3 Oxford Unicompartmental Knee Replacement bearings and to investigate the effects of resin type and manufacturing process.

Methods

A total of 63 patients with at least ten years’ follow-up with three bearing types (1900 resin machined, 1050 resin machined, and 1050 resin moulded) were recruited. Patients underwent full weight-bearing model-based radiostereometric analysis to determine the bearing thickness. The linear wear rate was estimated from the change in thickness divided by the duration of implantation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 28 - 28
1 Mar 2012
Owen JM Tong A Mandalia V Cronin M Waite J Deo S
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The Oxford mobile bearing unicompartmental knee replacement (UKR) is a validated, highly successful implant with an excellent ten-year survivorship. From November 2001 to September 2006 three hundred and eighty two patients who had a medial cemented Oxford Unicompartmental knee replacement (Biomet, Bridgend, UK) via a minimally invasive approach were prospectively entered into a database and followed up as per departmental policy in the specialist joint assessment clinic. We have noted a minority of patients have persistent postoperative pain and/or mechanical symptoms resistant to the standard postoperative therapies. We report the outcome of 22 patients who had an arthroscopy for persistent pain and/or mechanical symptoms a median of 15 months (range 4 months – 31 months) following medial unicompartmental knee replacement. The median follow up time following arthroplasty was 38 months (range 16 months – 63 months). Post arthroscopy we divided our study patients into two groups; those who had an improvement in symptoms and those who had none. These groups were then compared, with particular reference to demographics, check radiographs and arthroscopic findings. The results showed that patients with anterior or anteromedial symptoms in whom a medial rim of scar tissue was identified and debrided sixty seven percent had a significantly increased probability of symptomatic improvement (p<0.005). In addition men appeared to significantly improve more that women (p<0.043). When performed this therapeutic intervention many prevent or at least defer the need for early revision to total knee replacement in some cases and we have no complications as a result of the arthroscopic intervention. This observational study provides evidence for a role for arthroscopy in selected patients with pain following unicompartmental knee replacement


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 26 - 26
1 Mar 2012
Gulati A Pandit H Gill HS Price AJ Dodd CAF Murray DW
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INTRODUCTION. Mobile bearing unicompartmental knee replacement (UKR) is an accepted treatment for patients with isolated medial unicompartmental knee osteoarthritis (OA) with a full thickness cartilage loss. The aim of this study was to determine if this recommendation was correct and if the procedure could be used for partial-thickness cartilage loss. METHODS. 1053 Oxford medial UKRs were studied prospectively. The knees were divided into two groups; partial-thickness cartilage loss (PTCL) group and the full thickness-cartilage loss (FTCL) group. The primary outcome measure was the total Oxford Knee Score (OKS, 0 to 48) at the time of final follow up. The groups were also compared for the change in OKS (?OKS) and the proportion of patients that were considered to have benefited substantially from surgery (?OKS >5). RESULTS. There were 21 knees in the PTCL group, with a mean age of 61 years (SD 13) and mean follow-up of 1.7 years (SD 1.0). There were 1032 knees in the FTCL group, with a mean age of 66 years (SD 10) and mean follow-up of 3.9 years (SD 2.5). The PTCL group had a significantly lower (p=0.03) total OKS (mean 35.8, SD 10.7) at final review than the FTCL group (mean 39.8, SD 8.5). There was no significant difference in pre-operative or ?OKS between the groups. However the proportion of patients that did not have substantial benefit from surgery (?OKS>5) was significant lower (p=0.04) in the PTCL group. CONCLUSIONS. The results confirm that a good outcome can routinely be achieved with UKR if there is bone-on-bone. If there is partial loss of cartilage the results are less predictable. Although some patients do well, a higher proportion do not benefit from the surgery. It may be that in a subgroup of these patients the pain did not initially arise from the partially damaged cartilage. We therefore recommend that the Oxford Knee should only be used for medial OA if there is bone on bone


The Bone & Joint Journal
Vol. 103-B, Issue 7 | Pages 1261 - 1269
1 Jul 2021
Burger JA Zuiderbaan HA Sierevelt IN van Steenbergen L Nolte PA Pearle AD Kerkhoffs GMMJ

Aims

Uncemented mobile bearing designs in medial unicompartmental knee arthroplasty (UKA) have seen an increase over the last decade. However, there are a lack of large-scale studies comparing survivorship of these specific designs to commonly used cemented mobile and fixed bearing designs. The aim of this study was to evaluate the survivorship of these designs.

Methods

A total of 21,610 medial UKAs from 2007 to 2018 were selected from the Dutch Arthroplasty Register. Multivariate Cox regression analyses were used to compare uncemented mobile bearings with cemented mobile and fixed bearings. Adjustments were made for patient and surgical factors, with their interactions being considered. Reasons and type of revision in the first two years after surgery were assessed.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 2 | Pages 283 - 283
1 Feb 2007
Glasgow M