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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_3 | Pages 59 - 59
23 Feb 2023
Rahardja R Mehmood A Coleman B Munro J Young S
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The optimal timing of when to perform manipulation under anesthesia (MUA) for stiffness following total knee arthroplasty (TKA) is unclear. This study aimed to identify the risk factors for MUA following primary TKA and whether performing an “early” MUA within 3 months results in a greater improvement in range of motion. Primary TKAs performed between January 2013 and December 2018 at three tertiary New Zealand hospitals were reviewed. International Classification of Diseases discharge coding was used to identify patients who underwent an MUA. Multivariate Cox regression was performed to identify patient and surgical risk factors for MUA. Pre- and post-MUA knee flexion angles were identified through manual review of operation notes. Multivariate linear regression was performed to compare the mean flexion angles pre- and post-MUA, as well as the mean gain in flexion, between patients undergoing “early” (<3 months) versus “late” MUA (>3 months). 7386 primary TKAs were analyzed in which 131 underwent subsequent MUA (1.8%). Patients aged <65 years were two times more likely to undergo MUA compared to patients aged ≥65 years (2.5% versus 1.3%, adjusted hazard ratio = 2.1, p<0.001). Gender, body mass index, patient comorbidities or a history of cancer were not associated with the risk of MUA. There was no difference in the final post-MUA flexion angle between patients who underwent early versus late MUA (104.7 versus 104.1 degrees, p = 0.819). However, patients who underwent early MUA had poorer pre-MUA flexion (72.3 versus 79.6 degrees, p = 0.012), and subsequently had a greater overall gain in flexion compared to patients who underwent late MUA (mean gain 33.1 versus 24.3 degrees, p<0.001). Younger age was the only patient risk factor for MUA. A greater overall gain in flexion was achieved in patients who underwent early MUA within 3 months


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_5 | Pages 39 - 39
1 Apr 2019
Izant TH Tong-Ngork S Wagner J
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Introduction. Manipulation under anesthesia (MUA) after total knee arthroplasty (TKA) helps restore range of motion. This study identifies MUA risk factors to support early interventions to improve functionality. Methods. Data was retrospectively reviewed in 2,925 primary TKAs from October 2013 through December 2015 from 13 orthopedic surgeons using hospital and private practice electronic medical records (EMR). Statistical analysis evaluated MUA and non-MUA groups, comparing demographic, operative, hospital-visit, and clinical factors. T-test, chi-square test, ANOVA and regression analysis were performed. Significance was set at p<0.05. Results. Of 2,925 TKAs, 208 MUAs were performed (7.1%) with no significant differences between groups in sex, BMI, or diabetes status. Mean age of the MUA group was 61.98 years old, and 66.89 years old in the non-MUA group (p<0.005). The ratio of MUA patients with high cholesterol was 3.37% (7/208), and 1.10% (30/2717) in the non-MUA group (p=0.014). The ratio of African-American patients in the MUA group was 6.73% (14/208), and 2.94% (80/2717) in the non- MUA group (p=0.003). Of cases with device data recorded in the EMR (n=1890), MUA incidence in patients receiving a cruciate-retaining (CR) device was 14.58% (50/343), and 9.57% (148/1547) in patients receiving a posterior-stabilized (PS) device (p=0.006). A CR-device patient was 52.35% more likely to undergo MUA than a PS-device patient (95% CI, 1.13–2.05). MUA rate by surgeon training was 6.7% for joint fellowship, 6.8% for general fellowship, and 12.0% for sports medicine fellowship (p=0.015). Further analysis showed that rate of CR-device use was 13.3% for joint-fellowship trained surgeons, 10.2% for general fellowship, and 74.7% for sports medicine fellowship (p<0.001). With the numbers available for this investigation, there were no significant differences found between groups in relation to surgeon, high-volume (>150 TKAs annually) or low-volume surgeons, length of stay, discharge disposition, or smoking status. Conclusion. MUA risk factors include a lower mean age, high cholesterol, African-American, surgeon fellowship training, and receiving a cruciate-retaining device


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 11 - 11
1 Mar 2017
Smith K Mitchell R Le D
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BACKGROUND. The need for post-operative manipulation under anesthesia (MUA) for stiffness after primary total knee arthroplasty is a frustrating complication that can lead to suboptimal outcomes if range-of-motion to a functional level is not regained. Implant morphology and kinematics, PCL imbalance, and soft-tissue balancing can all contribute to post-operative stiffness. Utilization of total knee arthroplasty components that replicate the native knee's medial ball and socket kinematics may lead to easier maintenance of flexion post-operatively compared to conventional components. PURPOSE. To determine if a medial pivot total knee arthroplasty design can reduce the need for post-operative MUA after primary total knee arthroplasty. METHODS. A retrospective chart review of primary total knee arthroplasties performed between 2013 and 2016 by a single fellowship-trained joint replacement surgeon was performed. Cases that met criteria for inclusion were: primary total knee arthroplasty, identifiable implant based on operative report and/or post-operative radiographs, immediate post-operative passive flexion against gravity of at least 110 degrees, and availability of post-operative follow-up notes documenting range-of-motion that was either satisfactory or necessitating need for MUA. The need for a MUA was deemed necessary if post-operative flexion was not beyond 90 degrees within six weeks of surgery. The percentage of patients requiring MUA for a group implanted with the EVOLUTION Medial Pivot System was compared to a group implanted with all other designs (Stryker Triathlon CR, PS, TS). RESULTS. One hundred fifty-six cases met criteria for inclusion and were reviewed. The Triathlon system was used predominantly in the first half of the study period and accounted for 65 (42%) of the cases performed. Six patients in this group underwent MUA and two patients required repeated MUA. An additional patient in the Triathlon group met the criteria for MUA but had other conditions which prevented the investigators from performing it. The percentage of patients who met the indication for MUA in the Triathlon group was 10.8%. The EVOLUTION system was used predominantly in the second half of the study period and accounted for 91 (58%) of the cases performed. There were two patients (2.2%) who met criteria for MUA and both patients subsequently underwent MUA. There was a statistically significant reduction in the number of patients meeting criteria for MUA in the EVOLUTION group compared with the Triathlon group (p=0.024). CONCLUSION. Utilization of a medial ball and socket design for primary total knee arthroplasty allows the polyethylene implant to control the position of the femur on the tibia. This design possibly allows for improved early maintenance of post-operative flexion, which may minimize the need for post-operative MUA. For any figures or tables, please contact authors directly (see Info & Metrics tab above).


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_5 | Pages 87 - 87
1 Mar 2017
Plate J Wohler A Brown M Fino N Langfitt M Lang J
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Introduction. Arthrofibrosis following total knee arthroplasty (TKA) is a complex and multifactorial complication that may require manipulation under anesthesia (MUA). However, patient and surgical factors that potentially influence the development of knee stiffness following TKA are not fully understood. The purpose of this study was to identify patient and surgical factors that may influence arthrofibrosis following TKA by assessing a cohort of patient that underwent MUA and comparing them to a matched cohort of patients without arthrofibrosis. Methods. The joints registry of a university hospital was searched for patient that underwent MUA following primary TKA between 2004 and 2013. Demographic and surgical information was obtained from the electronic medical record including range of motion (ROM), comorbidities and timing of MUA. Patients who underwent MUA were then double-matched by baseline (prior to primary TKA) knee ROM to patients who underwent primary TKA without postoperative arthrofibrosis during the same time period. Results. Fifty-two patients (56 TKAs, 71% female, mean BMI 32.2kg/m2) underwent MUA after TKA during the study period. MUA was performed a mean of 13.6 weeks after primary TKA. Study patient were then double-matched by baseline flexion (mean 107º±2º) to 111 patients (112 TKAs) with a similar mean baseline flexion (104º±2º, p=0.138). Patient requiring MUA were younger (mean age 56 vs. 64 years, p<0.001), had more comorbidities (5 vs. 3, p<0.001), and a higher number of previous knee surgery (56% vs. 21%, p<0.001) compared with controls. The risk for requiring MUA following primary TKA was significantly higher (2.4, p<0.001) in patient with previous knee surgery (arthroscopy for meniscal pathology, ACL reconstruction, osteotomies). Tourniquet time, length of stay, number of physical therapy sessions, blood loss >50 mL and any complication during the hospital stay were not found to be associated with increased risk of requiring MUA. Discussion. Younger patients with more comorbidities and a history of previous knee surgery were found to have significantly higher risk for developing arthrofibrosis and requiring MUA after primary TKA in the current study. Patients with this risk profile need to counseled regarding the risk for arthrofibrosis possibly requiring MUA after primary TKA


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 32 - 32
1 Jan 2016
Carroll K Newman J Holmes A Della Valle AG Cross MB
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Introduction. Stiffness after total knee arthroplasty is a common occurrence. Despite its prevalence, little is known as to which patients are at risk for poor range of motion after total knee arthroplasty. The purpose of this study was to determine the risk factors for manipulation under anesthesia (MUA) after total knee arthroplasty (TKA). Methods. Using a single institution registry, 160 patients who underwent a manipulation under anesthesia after total knee arthroplasty between 2007 and 2013 were retrospectively evaluated. Each patient was 1:1 matched by age, gender and laterality to a control group of 160 patients who did not require MUA after TKA. Risk factors for MUA were assessed, and included medical co-morbidities, BMI, prior operations, and preoperative range of motion. Results. There were 160 patients in each group, 48 males and 112 females. Patients who required a MUA after TKA had a significantly higher percentage of overweight patients with a BMI >25 (88% vs 76%, p=0.01, Odds ratio=2.18), and previous surgery including arthroscopy (60% vs 33%, P < 0.0001, Odds ratio=3.12). Patients that underwent an MUA had a higher but not significant prevalence of depression and anxiety (22% vs. 16%, p=0.20, Odds Ratio=1.44) and diabetes (15% vs. 8%, p=0.058, Odds Ratio=2.0). Average ROM was 3–110° (Range −10–130°) and 6–102° (Range 0–140°) in the MUA and control groups respectively. In the MUA group, 29% of patients had pre-operative flexion less than 90 degrees pre-operatively compared to 3% in the control group (p=0.02, Odds Ratio=6.6). While the average preoperative range of motion did not differ between the groups, there were a larger percentage of patients with severe limitations in range of motion who ended up needing a MUA after TKA compared to controls. Conclusion. Patients with increased BMI, preoperative range of motion less than 90°, and a history of prior operations should be counseled on the increased risk of requiring a MUA after TKA


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 35 - 35
1 Feb 2012
Sivardeen Z Paniker J Drew S Learmonth D Massoud S
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Background. Frozen Shoulder is a common condition which causes significant morbidity in people of working age. The 2 most popular forms of surgical treatment for this condition are Manipulation under Anaesthesia (MUA) or MUA plus Arthroscopic Capsular Release (ACR). Both treatment modalities are known to give good results, but no-one has compared the two to see which is better. Aim. To compare the outcome in patients with primary frozen shoulder, who are treated by either MUA or MUA plus ACR. Methods. 56 patients with primary frozen shoulder were treated by either MUA or MUA plus ACR. Each patient had their American Shoulder and Elbow Score (ASES), and their Oxford Shoulder Score (OSS) measured pre- and post-operatively. Results. The patients who had MUA plus ACR had a mean ASES of 19.6 pre-operatively, 78.3 at 6 months, and a mean of 80.1 at 12 months. The mean OSS was 32.5 pre-operatively, 53.6 at 6 months and 53.8 at 12 months. The patients who had a MUA had a mean ASES of 28.7 pre-operatively, 57.9 at 6 months and 58 at 12 months. The mean OSS was 33 pre-operatively, 42.5 at 6 months and 48 at 12 months. Conclusions. Both treatments give good results; MUA plus ACR give significantly superior results at 6 to 12 months post-operatively. However, there is no significant difference beyond 12 months


Bone & Joint Open
Vol. 1, Issue 7 | Pages 424 - 430
17 Jul 2020
Baxter I Hancock G Clark M Hampton M Fishlock A Widnall J Flowers M Evans O

Aims. To determine the impact of COVID-19 on orthopaediatric admissions and fracture clinics within a regional integrated care system (ICS). Methods. A retrospective review was performed for all paediatric orthopaedic patients admitted across the region during the recent lockdown period (24 March 2020 to 10 May 2020) and the same period in 2019. Age, sex, mechanism, anatomical region, and treatment modality were compared, as were fracture clinic attendances within the receiving regional major trauma centre (MTC) between the two periods. Results. Paediatric trauma admissions across the region fell by 33% (197 vs 132) with a proportional increase to 59% (n = 78) of admissions to the MTC during lockdown compared with 28.4% in 2019 (N = 56). There was a reduction in manipulation under anaesthetic (p = 0.015) and the use of Kirschner wires (K-wires) (p = 0.040) between the two time periods. The median time to surgery remained one day in both (2019 IQR 0 to 2; 2020 IQR 1 to 1). Supracondylar fractures were the most common reason for fracture clinic attendance (17.3%, n = 19) with a proportional increase of 108.4% vs 2019 (2019 n = 20; 2020 n = 19) (p = 0.007). While upper limb injuries and falls from play apparatus, equipment, or height remained the most common indications for admission, there was a reduction in sports injuries (p < 0.001) but an increase in lacerations (p = 0.031). Fracture clinic management changed with 67% (n = 40) of follow-up appointments via telephone and 69% (n = 65) of patients requiring cast immobilization treated with a 3M Soft Cast, enabling self-removal. The safeguarding team saw a 22% reduction in referrals (2019: n = 41, 2020: n = 32). Conclusion. During this viral pandemic, the number of trauma cases decreased with a change in the mechanism of injury, median age of presentation, and an increase in referrals to the regional MTC. Adaptions in standard practice led to fewer MUA, and K-wire procedures being performed, more supracondylar fractures managed through clinic and an increase in the use of removable cast. Cite this article: Bone Joint Open 2020;1-7:424–430


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_9 | Pages 19 - 19
1 Feb 2013
Sangster M Hetherington J Thomas W Owen J Woods D
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Manipulation under anaesthetic (MUA) is an established treatment for frozen shoulder. Frozen shoulder may coexist with other shoulder conditions, whose treatment may differ from MUA. One such condition is calcific tendonitis. Only one study to date documents treatment of patients with frozen shoulder and concurrent calcific tendinitis. The objective was to demonstrate that MUA and injection is a satisfactory treatment for concurrent diagnosis of frozen shoulder and calcific tendinitis. Patients with a clinical diagnosis of frozen shoulder and radiological evidence of calcific tendinitis were prospectively recruited from Jan 1999 – Jan 2009. Treatment by MUA and injection was performed. Clinical examination, Oxford Shoulder Scores and need for further treatment were used as outcome measures. Fourteen patients (median age 53.5 years) were identified with frozen shoulder and concurrent calcific tendinitis. Significant improvement in both Oxford Shoulder Score and range of movement was achieved following MUA (P values < 0.001). Two patients required further treatment (not for calcific tendinitis). This improvement was maintained in the long term (median 107 wks). It is our belief that MUA and injection is a safe and effective treatment, addressing the frozen shoulder with MUA takes priority, and as such frozen shoulder “trumps” other pathologies occurring simultaneously


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 235 - 235
1 Sep 2012
Yeoh D Nicolaou N Goddard R Willmott H Miles K East D Hinves B Shepperd J Butler-Manuel A
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A reduced range of movement post total knee replacement (TKR) surgery is a well recognised problem. Manipulation under anaesthesia (MUA) is a commonly performed procedure in the stiff post operative TKR. Long term results have been variable in the literature. We prospectively followed up 48 patients since 1996 from one centre, over an average of 7.5 years, (range 1 to 10 years) and report on the long term results. The mean time to MUA post TKR was 12.3 weeks (range 3 to 48). Pre MUA, the mean flexion was 53°. The mean immediate passive flexion post MUA was 97°, an improvement of 44° (Range 10° to 90°, CI < 0.05). By one year, the mean flexion was 87°, improvement of 34°, (range −15° to 70°, CI< 0.05). At ten years the mean flexion was 86°. We found no difference between those knees manipulated before or after 12 weeks. In addition there was no difference found in those knees which had a pre TKR flexion of greater or less than 90°. There were no complications as a result of MUA. However, one patient was eventually revised at two years secondary to low grade infection. Our findings show that MUA is safe and effective method at improving the range of motion in a stiff post operative TKR. The improvement is maintained in the long term irrespective of time to MUA and range of motion pre TKR


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 156 - 156
1 Dec 2013
Ranawat A White P
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Objective:. Patient-specific or “custom” total knee replacements have been designed to fit the arthritic knee in primary total knee arthroplasty (TKA) better than “off-the-shelf” implants. Using computer technology, patient-specific cutting-blocks and custom-made implants are created to more accurately fit the contour of the knee and reproduce the anatomic J-curve with the hope of providing a better functional outcome. Purpose:. This retrospective, matched-pair study evaluates manipulation under anesthesia (MUA) rates in cemented patient-specific cruciate-retaining (PSCR) TKA compared to that in both cemented posterior-stabilized (PS) and non-cemented cruciate-retaining rotating-platform (NC CR RP) TKA. Materials and Methods:. From 2010 through November of 2012, 21 PSCR TKAs were performed in 19 patients. Using medical records from our patient database, these patients were matched for age, side, deformity, diagnosis, Charnley Class, and preoperative range of motion (ROM) with 42 PS TKAs performed during the same time period by the same surgeon using the same intra- and post-operative protocols. Additionally, 11 NC CR RP TKA were performed and evaluated based on the same criteria. Pre- and postoperative radiographs were performed using criteria as described by The Knee Society. Results:. Preoperatively the custom CR RP TKA cohort had a larger average ROM compared to the PS TKA cohort (P-value = 0.006). Postoperatively, however, the custom CR RP TKA cohort overall was found to have a significantly decreased average ROM compared to both the PS and NC CR RP TKA cohorts (2.0°–110.6° P-value = 0.0002 and 2.4°–117.3° P-value = 0.0003, respectively). 6 of the 21 (28.6%) PSCR TKAs performed underwent MUA to improve postoperative ROM. One manipulation was unsuccessful and the patient is scheduled for revision for arthrofibrosis. No patients in either the matched PS group or the CR RP group underwent postoperative MUA. Clinical and radiographic analysis including pre-operative ROM, deformity, side, Charnley Class, posterior tibial slope angle, epicondylar axis and posterior condylar offsets provided no insight into the reason for this higher MUA rate in the PSCR knees. Conclusion:. MUA rates in the patient-specific TKA group were significantly higher than that in the matched PS and NC CR RP groups. No correlations were found to clearly indicate the cause of the higher MUA rate among the PSCR knees. Early manipulation is recommended for stiffness with these custom devices. Level of Evidence: Level III, Retrospective comparative study. Keywords: Patient-specific total knee, Manipulation, TKA


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OBJECTIVE. Post TKR manipulation under anesthesia is required when post operatively patients don't achieve desired range of motion. The rates quoted in various western literature ranges from 1 to 2 %. A knee is considered to be stiff when the patient fails to achieve 60 degrees of flexion. The objective of the study was to find out the differentiating factor responsible for low rate of MUA in Indian post TKR patients as compared to Anglo-Saxon population. MATERIAL & METHODS. We studied 100 consecutive patients operated from January 2016. The following parameters of these 100 patients were recorded. Pre-op ROM. Age and Sex of the TKR patient. Duration of home physiotherapy. Post opROM. All patients received post operative physiotherapy at home every day for first 2 weeks, 3 times a week for next 2 weeks and then once a week for next two weeks. The implant used was Maxx Freedom knee (PS design). RESULTS. Of the 300 TKR patients 270 were females and 30 were males. The age range for male patients was 65 to 87 years with a mean of 73 years. The age range of female patients was 65 to 83 years with a mean of 71 years. The mean range of motion achieved was 121 degrees. Only one of our patient required manipulation under anesthesia.(0.333%). CONCLUSION. Our rate of MUA is totally different from that of reported from Western world. According to us home physiotherapy is the main differentiating factor responsible for this low rate. Hence we strongly advocate personalized home physiotherapy post TKR with constant feedback mechanism between the operating doctor and the treating physiotherapist


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_7 | Pages 24 - 24
1 May 2015
Chaudhury S Hurley J White HB Agyryopolous M Woods D
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Distal radius and ulna fractures are a common paediatric injury. Displaced or angulated fractures require manipulation under anaesthetic (MUA) with or without Kirchner (K) wire fixation to improve alignment and avoid malunion. After treatment a proportion redisplace requiring further surgical management. This study aimed to investigate whether the risk of redisplacement could be reduced by introducing surgical treatment guidelines to ascertain whether MUA alone or the addition of K wire fixation was required. A cohort of 51 paediatric forearm fractures managed either with an MUA alone or MUA and K wire fixation was analysed to determine fracture redisplacement rates and factors which predisposed to displacement. Guidelines for optimal management were developed based on these findings and published literature and implemented for the management of 36 further children. A 16% post-operative redisplacement rate was observed within the first cohort. Redisplacement was predicted if an ‘optimal reduction’ of less than 5° of angulation and/or 10% of translation was not achieved and no K wire fixation utilised. Adoption of the new guidelines resulted in a significantly reduced redisplacement rate of 6%. Implementation of departmental guidelines have reduced redisplacement rates of children's forearm fractures at Great Western Hospital


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 87 - 87
1 Feb 2017
Dabuzhsky L Neuhauser-Daley K Plaskos C
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Arthrofibrosis remains a dominant post-operative complication and reason for returning to the OR following total knee arthroplasty. Trauma induced by ligament releases during TKA soft tissue balancing and soft tissue imbalance are thought to be contributing factors to arthrofibrosis, which is commonly treated by manipulation under anesthesia (MUA). We hypothesized that a robotic-assisted ligament balancing technique where the femoral component position is planned in 3D based on ligament gap data would result in lower MUA rates than a measured resection technique where the implants are planned based solely on boney alignment data and ligaments are released afterwards to achieve balance. We also aimed to determine the degree of mechanical axis deviation from neutral that resulted from the ligament balancing technique. Methods. We retrospectively reviewed 301 consecutive primary TKA cases performed by a single surgeon. The first 102 consecutive cases were performed with a femur-first measured resection technique using computer navigation. The femoral component was positioned in neutral mechanical alignment and at 3° of external rotation relative to the posterior condylar axis. The tibia was resected perpendicular to the mechanical axis and ligaments were released as required until the soft tissues were sufficiently balanced. The subsequent 199 consecutive cases were performed with a tibia-first ligament balancing technique using a robotic-assisted TKA system. The tibia was resected perpendicular to the mechanical axis, and the relative positions of the femur and tibia were recorded in extension and flexion by inserting a spacer block of appropriate height in the medial and lateral compartments. The position, rotation, and size of the femoral component was then planned in all planes such that the ligament gaps were symmetric and balanced to within 1mm (Figure 1). Bone resection values were used to define acceptable limits of implant rotation: Femoral component alignment was adjusted to within 2° of varus or valgus, and within 0–3° of external rotation relative to the posterior condyles. Component flexion, anteroposterior and proximal-distal positioning were also adjusted to achieve balance in the sagittal plane. A robotic-assisted femoral cutting guide was then used to resect the femur according to the plan (Figure 2). CPT billing codes were reviewed to determine how many patients in each group underwent post-operative MUA. Post-operative mechanical alignment was measured in a subset of 50 consecutive patients in the ligament balancing group on standing long-leg radiographs by an independent observer. Results. Post-operative MUA rates were significantly lower in the ligament balancing group (0.5%; 1/199) than in the measured resection group (3.9%; 4/102), p=0.051. 91.3% (42/46) of knees were within 3° and 100% (46/46) were within 4° of neutral alignment to the mechanical axis post-operatively in the ligament balancing group. Conclusions. Gap driven femoral based planning in TKA resulted in a significantly lower post-operative manipulation rate than in the measured resection approach, while maintaining acceptable overall alignment to the mechanical axis


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 72 - 72
1 Sep 2012
Cohen D Cartwright-Terry M Pope J Davidson J Santini A
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Purpose. To review the outcomes of patients undergoing manipulation under anaesthetic (MUA) after primary total knee arthroplasty (TKA) and predict those that may require such a procedure. Methods. Prospective analysis of patients who required MUA post TKA performed by two surgeons using the same prosthesis from 2003 to 2008. Compared to a control group of primary TKA matched for age, gender and surgeon. All patients in both groups had pre- and post-operative measurements of range of movement. Risk factors were identified including warfarin and statin use, diabetes and body mass index. Results. Seventy-two patients required an MUA out of 1313 TKAs (5.5%) compared to a control group of 50 patients. The mean arc of motion preoperatively was 89.0° (MUA group) vs 92.2° (control) (p=0.47), at discharge 71.0° vs 76.8° (p< 0.05) and 6 weeks follow-up 64.0° vs 97.3° (p< 0.0001). Post manipulation the mean arc of motion was 108° on table, 83.1° at 3 months follow-up and 81.9° at 12 months. Patients whose manipulation was within 3 months of TKA (23 patients) improved their mean arc of motion from 53.6° to 78.0° (p< 0.0025), those 3–12 months (42 patients) from 67° to 83.0° (p< 0.0001) and those >12 months (7 patients) 81° to 89° (p=0.32). Mean increase of extension was 3.7° on table and 3.6° at 12 months. Mean flexion increase was 40.5° on table and 15.7° at 12 months. The relative risk factor for requiring an MUA was 6.97 warfarin (p< 0.05), 1.58 statins, 2.85 diabetes and 1.17 obesity. Conclusions. MUA following primary TKA improves their range of motion if done within 12 months, however only 50% improvement is maintained. Patients with less than 75° flexion at discharge or those on warfarin therapy are likely to require a manipulation to improve their range of movement


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_6 | Pages 14 - 14
1 May 2015
Yassin M Daoud M Giurea M
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There are many types of arthroplasties for the 1st MTPJ, but still the treatment of advance Hallux rigidus remains controversial. In this study we are reporting the outcome of the North Star hemicap at 6 months. A series of patients under the care of a single surgeon were followed using the Manchester - Oxford Foot Questionnaire (MOXFQ) at 6months post operation, and a satisfaction question was asked. The operations were between August 2011 and August 2013. A total of forty five arthroplasties were implanted in 44 patients. Thirty four of them were female and 9 were male. The average age was 56 years (range 37–77 years). Twenty six out of them (59%) needed an MUA + a local anaesthetic and steroid injection of the prosthetic joint at 2 to 14 months (average 6 months) post implantation. In these patients the MOXFQ was filled at 6months post the MUA and injection. Four of them were left out of the study because they were less than 6months post MUA. One patient had his implant removed and changed to fusion at his request at 14 months post implantation. Forty one patients were satisfied and would recommend the operation, 2 were disappointed with the degree of movement but would still recommend the operation and one had it revised to fusion. The average MOXFQ was 12/64. In conclusion, high percentage of patients needed a second operation, but the scores are reasonably low and almost all patients would recommend it. Further follow up of these patients is needed for at least 5years but the early results are showing it to be a good alternative for fusion


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XII | Pages 13 - 13
1 Apr 2012
Thomas W Sangster M Kirubandian R Beynon C Jenkins E Woods D
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Manipulation under anaesthetic (MUA) for the treatment of frozen shoulder is well established and effective however timing of surgery remains controversial. Intervention before 9 months has previously been shown to be associated with improved outcome. We test this theory by measuring Oxford Shoulder Score (OSS), re-MUA and subsequent surgery rate. A retrospective review of a prospectively collected, single surgeon, consecutive patient series revealed 244 primary frozen shoulders treated by MUA within 4 weeks of presentation. The mean duration of antecedent symptoms was 28 weeks (95% CI 4-44 weeks) and time to follow up was 26 days (95% CI 11-41 days). The mean OSS improved by 16 points (2-tailed t test p< 0.001) with a mean follow up OSS of 43 (95% CI 38-48). 195 shoulders were manipulated before 38 weeks (9 months) and had the same mean change in OSS (16) as the 49 shoulders manipulated after 38 weeks. 48 shoulders, including 15 diabetic shoulders required further MUA. 8 shoulders had subsequent surgery. These events were also independent of antecedent symptom duration. Early MUA does not appear to produce improved outcomes when compared to later intervention but we note does result in an earlier return to function


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_14 | Pages 73 - 73
1 Mar 2013
Rollinson P Wicks L Kemp M
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Introduction. A recent retrospective study of distal femoral physeal fractures (DFPFs) suggested closed manipulation alone has a high incidence of re-displacement, malunion or physeal bar formation. The paper concluded that all displaced DFPFs require internal fixation, and breaching the physis with k-wires is safe. We agree that hyper-extension/flexion injuries need stabilisation using k-wires but, in our experience, purely valgus/varus deformities can be successfully managed by manipulation under anaesthesia (MUA) and a moulded cylinder cast. Method. We prospectively observed DFPFs presenting over 12 months. Departmental policy is to treat varus/valgus deformities by MUA, with cylinder casting providing 3 point fixation. Hyper-extension/flexion injuries are reduced on a traction table. 2mm cross k-wiring is performed, leaving the wires under the skin, and a cylinder plaster applied. A post-operative CT scanogram accurately assesses limb alignment. Patients are mobilised immediately using crutches and weight-bearing as pain allows. Plaster and k-wires are removed after 4–5 weeks. Scanogram is then repeated, and again at 6 months and 1 year. Results. 17 cases presented over 1 year. 16 were male, with a median age of 15. 13 were injured playing soccer, 1 in a motor vehicle accident and 3 by other mechanisms. Internal fixation supplemented reduction in 13 cases. 1 patient required repeat MUA and k-wiring when post-operative scanogram identified significant varus mal-alignment. In all cases, cylinder casting was unproblematic and range of movement quickly recovered after plaster/wire removal. To date none have developed significant malunion or growth arrest requiring intervention. Conclusion. DFPFs are uncommon, almost always occurring in teenage males. Accurate reduction and stabilisation is vital to restore and maintain a correct mechanical axis. MUA and cylinder casting is adequate in appropriate cases. Early imaging with CT scanogram can detect mal-alignment. Growth arrest is unusual and unlikely to be significant in most patients, who are approaching skeletal maturity. NO DISCLOSURES


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_15 | Pages 52 - 52
1 Aug 2017
Sculco P
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Stiffness after total knee arthroplasty (TKA) is a common problem occurring between 5% and 30% of patients. Stiffness is defined as limited range of motion (ROM) that affects activities of daily living. A recent International Consensus on definition of stiffness of the knee graded stiffness as mild, moderate or severe (90–100, 70–89, <70, respectively) or an extension deficit (5–10, 11–20, >20). Stiffness can be secondary to an osseous, soft tissue, or prosthetic block to motion. Heterotopic bone or retained posterior osteophytes, abundant fibrotic tissue, oversized components with tight flexion or extension gaps or component malrotation can all limit knee motion. Infection should always be considered in the knee that gradually loses motion. Alternative causes include complex regional pain syndrome and Kinesiophobia that can limit motion without an underlying mechanical cause. The evaluation of knee stiffness radiographs of the knee and cross-section imaging should be performed if component malrotation is considered. A metal suppression MRI assists in quantifying the extent of fibrosis and its location in the anterior or posterior compartment of the knee. Inflammatory markers and joint aspiration as indicated to rule out infection. Arthrofibrosis, or post-surgical fibrosis, is related to abnormal scar formation after surgery that leads to loss of motion. The cause of arthrofibrosis is multifactorial and likely related to genetic host factors. Current research is focusing on molecular signatures that may better identify patients at risk. In addition, therapeutic interventions are being studied that best prevent fibrosis and its recurrence and include the use of anti-inflammatories, corticosteroids, Colchicine, biologic medications (IL-1 inhibitors) and low-dose radiation. Early treatment of the stiff TKA includes physical therapy and manipulation under anesthesia (MUA). MUA performed within 3 months may have the greatest increase in ROM but notable improvement can occur up to 6 months after TKA. After six months, arthroscopic or open surgery is recommended for persistent stiffness. Arthroscopic lysis of adhesions can improve ROM greater than 1 year after index TKA. Average improvement of ROM for both MUA and arthroscopic lysis of adhesions (usually in conjunction with MUA) is approximately 30 degrees. The outcome after open lysis of adhesions are reportedly poor but current adjuvant therapies may improve these clinical outcomes as this addresses the biologic, in addition to the mechanical, basis of fibrosis. Component revision performed for component malposition and stiffness has variable outcomes but a recent study reports a mean increase in ROM of 20 degrees and a modest improvement in overall knee function. The cause of post-operative stiffness after TKA is a complex interplay of the patient, surgeon, and post-operative factors. Correct diagnosis of the underlying cause of the stiff total knee is essential to optimizing treatment outcomes. More research in needed in how to best prevent and treat the biologic risk factors and pathways that contribute to post-surgical fibrosis


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 511 - 511
1 Dec 2013
Rogers J Barnes L
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Postoperative stiffness is a relatively uncommon issue in total knee arthroplasty (TKA). However, it can be a debilitating complication when it occurs. Manipulation under anesthesia (MUA) is commonly used as the primary treatment modality following failed physiotherapy. The ADVANCE® Medial Pivot Knee (Wright Medical Technology) was created in an effort to prevent stiffness postoperatively and increase range of motion. The EVOLUTION® Medial Pivot Knee is a second generation design that builds upon the technology of the ADVANCE® knee. We performed a retrospective review of prospectively collected data on 881 primary medial pivot knees (592 ADVANCE® knees, 289 EVOLUTION® knees). We theorized that the design changes made to the EVOLUTION® knees might contribute toward reducing the need for MUA. We found that the EVOLUTION® knees required significantly fewer manipulations under anesthesia (p = 0.036). The design modifications made to the EVOLUTION® knees may have contributed to the lower rate of MUA


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 90 - 90
1 May 2016
Kawashima H Nakano S Yoshioka S Toki S Kashima M Nakamura M Chikawa T Kanematsu Y Sairyo K
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Flexion contracture sometimes occurs after primary total knee arthroplasty (TKA). In most cases, flexion contracture after TKA gradually improves over time. However, some severe cases require manipulation or revision surgery. We searched our clinical database for patients who underwent primary TKA at our institution between 2008 and 2015. By reviewing patient records, we identified three patients (one man and two women) with a severe flexion contracture 30° after primary TKA. Although all three patients gained more than 120° in flexion intraoperatively, they developed flexion contracture after discharge from our institution. We performed manipulation under anaesthesia (MUA) for all three cases several months later. The two female patients had improved range of motion (ROM) right after the manipulation. However, one of them regained flexion contracture 1 year after the MUA. We report the details of the male patient, who had the worst flexion contracture (−60°). An 80-year-old man had right knee osteoarthritis. His history indicated only hypertension. The right knee ROM before the TKA was −20° extension and 135° flexion. His radiographs showed advanced-stage osteoarthritis. We performed cemented TKA (posterior stabiliser design). Three weeks after the operation, his right knee pain improved. The right knee ROM was −10° extension and 100° flexion just before discharge. However, he returned to our institution because of right knee pain and flexion contracture 31 months after the surgery. The flexion contracture gradually worsened without any trauma. When he returned, the right knee ROM was −60° extension and 135° flexion. Manipulation under general anaesthesia was not effective. Therefore, we performed revision TKA immediately. We excised the scar tissue of the posterior knee joint. Then, we shortened the distal femoral end by 1 cm and reduced the size of the femoral component. After the operation, the right knee ROM was improved to −10° flexion and 130° extension. The reported prevalence of stiffness after TKA was from 1.3% to 13%. Although the deleterious effects of persistent flexion contractures > 15° is well understood, whether they resolve with time or need surgical intervention is controversial. MUA is generally the initial option for patients with flexion contractures, with the possibility of some improvement. If severe flexion contracture remains after manipulation, revision TKA, which may be considered as a useful treatment option, should be considered