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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_10 | Pages 26 - 26
1 Jun 2023
Georgiannakis A Glynou SP Ackling E Bystrzonowski N Pafitanis G Diver A
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Introduction. Despite the established guidelines on lower extremity free flap reconstruction by the British Orthopaedic Association Standard for Trauma (BOAST-4) the post-operative care has yet to be standardised. There is currently no coherent evidence in the literature regarding clinical monitoring, warming, dangling and compression; the optimal regimes and their respective physiological benefits. The aim of this study is to survey all UK Major Trauma Centres (MTCs) with regards to the post-operative care of lower extremity free flaps and elucidate the current protocols for clinical monitoring, warming, dangling and compression. Materials & Methods. All UK-based adult MTCs were surveyed. We formulated a detailed questionnaire to enquire about the post-operative care of lower extremity free flap reconstructions; the number of free flap reconstructions per month and take backs per month and for which post-operative methods a protocol is used in each MTC. We asked specific questions concerning: clinical monitoring, warming, dangling and compression. This questionnaire was distributed to consultant leads in the form of multiple choice questions, with an option of free-text box for further comments, using JISC online surveys. Results were analysed in Excel and presented in percentages. Results. The 28 adult MTCs were contacted. The results showed a lack of formal regional protocols with great variability, suggesting there is no general consensus on post-operative care of lower extremity free flap reconstructions with regards to clinical monitoring, warming, dangling and compression. Conclusions. This survey of UK MTCs on the post-operative protocols for lower extremity free flap reconstruction demonstrated lack of evidence, consensus and large variability in common practice which requires standardisation


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_19 | Pages 6 - 6
22 Nov 2024
Valand P Hotchen A Frank F McNally M Ramsden A
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Aim. To report outcomes of soft tissue reconstruction using free tissue transfer for the treatment of tibial osteomyelitis as part of a single-stage, ortho-plastic procedure. Method. Patients who underwent ortho-plastic reconstructive surgery to excise tibial osteomyelitis in combination with free tissue transfer in one stage were included. Patients underwent surgery between 2015 and 2024 in a single specialist centre within the UK. Baseline patient information, demographics, and infection information was recorded. Adverse outcomes were defined as (i) flap salvage required, (ii) flap failure and (iii) recurrence of infection. Patient reported quality of life was measured using the EuroQol EQ-5D-5L index score. Pre-operative QoL was compared to QoL at 1 year with a control group of 53 similar patients who underwent surgical treatment for tibial osteomyelitis without a free flap (local flap or primary closure). Results. Ninety-three patients were eligible for inclusion, with a mean age of 52 years (range 18–90). 77/93 (82.8%) had a free muscle flap with the remainder (17.2%) receiving a fasciocutaneous flap. The donor tissue was defined as 57 gracilis, 6 latissimus dorsi, 14 hemi-latissimus dorsi, and 16 anterolateral thigh. The recipient area of the tibia was distal 1/3 in 52 cases, middle 1/3 in 27 cases and proximal 1/3 in 12 cases. The average flap ischaemic time was 70 minutes (range 28 to 125). Seven patients (7.5%) required urgent flap salvage at a median time of 1.0 day (range 0.5 – 4.0). Of these, 4 (4.3%) went on to have total flap failure, of which 2 patients underwent below knee amputation subsequently. Flap failure was due to either arterial (n=2) or venous (n=2) anastomotic thrombus. There were 3 (3.2%) episodes of confirmed infection recurrence within the first year after the index procedure. EQ-index scores at 1-year post-operatively were significantly improved when compared to pre-operative scores (p=0.008). At 1-year post-operatively, EQ-index scores in patients who underwent free flap was similar compared to local flaps (p=0.410) and in those who underwent primary closure for tibial osteomyelitis (p=0.070). Conclusions. Microsurgical single stage surgery can achieve high flap survival rate (95.7%). Free flaps fail early due to anastomotic thrombus with no late failures seen. Free tissue transfer does not appear to give inferior QoL compared to matched patients with local flaps or direct closure in tibial osteomyelitis


The Bone & Joint Journal
Vol. 102-B, Issue 6 Supple A | Pages 176 - 180
1 Jun 2020
Lee G Colen DL Levin LS Kovach SJ

Aims. The integrity of the soft tissue envelope is crucial for successful treatment of infected total knee arthroplasty (TKA). The purpose of this study was to evaluate the rate of limb salvage, infection control, and clinical function following microvascular free flap coverage for salvage of the infected TKA. Methods. We retrospectively reviewed 23 microvascular free tissue transfers for management of soft tissue defects in infected TKA. There were 16 men and seven women with a mean age of 61.2 years (39 to 81). The median number of procedures performed prior to soft tissue coverage was five (2 to 9) and all patients had failed at least one two-stage reimplantation procedure. Clinical outcomes were measured using the Knee Society Scoring system for pain and function. Results. In all, one patient was lost to follow-up prior to 12 months. The remaining 22 patients were followed for a mean of 46 months (12 to 92). At latest follow-up, four patients (18%) had undergone amputation for failure of treatment and persistent infection. For the other 18 patients, 11 patients (50%) had maintained a knee prosthesis in place while seven patients had undergone resections for persistent infection but retained their limbs (32%). Reoperations were common following coverage and reimplantation. The median number of additional procedures was two (0 to 6). Clinical function was poor in patients who underwent reimplantation and retained a knee prosthesis following free flap coverage with a mean KSS score for pain and function of 44 (0 to 70) and 30 (0 to 65), respectively. All patients required an assistive device. Extensor mechanism problems and extensor lag requiring bracing were common following limb salvage and prosthesis reimplantation. Conclusion. Microvascular tissue transfer for management of infected TKA can be successful in limb salvage (82%) but clinical outcomes in salvaged limbs were poor. Cite this article: Bone Joint J 2020;102-B(6 Supple A):176–180


The Journal of Bone & Joint Surgery British Volume
Vol. 80-B, Issue 1 | Pages 86 - 90
1 Jan 1998
Hahn SB Lee JW Jeong JH

We reviewed 11 patients who had been treated between January 1986 and June 1994 for severe foot injuries by tendon transfer with microvascular free flaps. Their mean age was 5.6 years (3 to 8). Five had simultaneous tendon transfer and a microvascular free flap and six had separate operations. The mean interval between the tendon transfer and the microvascular free flap was 5.8 months (2 to 15) and the mean time between the initial injury and the tendon transfer was 9.6 months (2 to 21). The anterior tibial tendon was split in five of six cases. The posterior tibial tendon was used three times and the extensor digitorum longus tendon twice. The mean follow-up was 39.7 months (24 to 126). There were nine excellent and two good results. Postoperative complications included loosening of the transferred tendon (2), plantar flexion contracture (1) mild flat foot deformity (1) and hypertrophic scars (2). We recommend tendon transfer with a microvascular free flap in children with foot injuries combined with nerve injury and extensive loss of skin, soft tissue and tendon


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 40 - 40
1 Oct 2019
Lee G Colen D Levin LS Kovach S
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Introduction. Infection following TKA can be a catastrophic complication that can cause significant pain, morbidity and jeopardize limb viability. The integrity of the soft tissue envelope is critical to successful treatment and infection control. While local tissue flaps can provide adequate coverage for most soft tissue defects around the knee, there are cases that require salvage using microvascular free tissue transfers. The purpose of this study is to evaluate the 1) rate of limb salvage; 2) infection control; and 3) clinical function following free flap coverage for salvage of the infected TKA. Materials and Methods. We retrospectively reviewed 23 microvascular free tissue transfers for management of soft tissue defects in infected TKA. There were 16 men and 7 women with a mean age of 61.2 years (range 39–81). The median number of procedures performed prior to soft tissue coverage was 5 (range 2–9) and all patients had failed at least one 2 stage reimplantation procedure. Clinical outcomes were measured using the Knee Society Scoring system for pain and function. The rate of limb salvage and infection control were recorded. Results. One patient was lost to follow up prior to 12 months. The remainder 22 patients were followed for a mean of 46 months (range 12–92 months). At latest follow up, 4 patients (18%) had undergone amputation for failure of treatment and persistent infection. For the remainder 18 patients, 11 patients (50%) have maintained a knee prosthesis in place while 7 patients had undergone resections for persistent infection but maintained their limbs (32%). Reoperations were common following coverage and reimplantation procedure. The median number of additional procedures was 2 (range 0–6). Clinical function was poor in patients who were reimplanted and retained a knee prosthesis following free flap coverage with a mean KSS score for pain and function of 44 (range 0–70) and 30 (range 0–65). All patients required an assistive device. Extensor mechanism problems and extensor lag requiring bracing were common following limb salvage and prosthesis reimplantation. Conclusions. Microvascular tissue transfer for management of infected TKA can be successful in limb salvage (81%) but clinical outcomes in salvaged limbs were poor. The data should be used to counsel patients when contemplating limb salvage in these severe, end-stage cases. For figures, tables, or references, please contact authors directly


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_15 | Pages 70 - 70
1 Dec 2015
Olesen U Lykke-Meyer L Bonde C Eckardt H Singh U Mcnally M
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Open tibial fractures have a high infection risk making treatment difficult and expensive. Delayed skin closure (beyond 7 days) has been shown to increase the infection rate in several studies (1). We aim to calculate the cost of infection as a complication of open tibial fractures and to determine the effect of delayed skin closure on this cost. We retrospectively reviewed all records of patients treated with a free flap in our institution for an open tibial fracture from 2002 to 2013. We calculated direct costs of treatment by the DRG-values (2014 figures), based on length of stay (LOS), diagnosis, orthopaedic and plastic surgical procedures and the corresponding reimbursement. The primary goal was to establish the extra cost incurred by an infection, compared to treating an uninfected open tibial fracture. The cost efficiency saving of early soft tissue cover was also investigated. We analysed 45 injuries in 44 patients. All patients were treated with debridement, stabilization, prophylactic antibiotics and free flap cover. Infection increased the mean total LOS in hospital from 28.0 to 63.8 days. The presence of an infection increased the cost of treatment from a mean of €49.301 for uninfected fractures compared to a mean of €67.958 for infected fractures. Achieving skin cover within 7 days of injury decreased the infection rate from 60% to 27% (total series rate 48%). The provision of early soft tissue cover (before 7 days) for all patients would have saved an average of €18.658 per patient. The development of an infection after a severe open tibial fracture greatly increases the cost of treatment. Early soft tissue cover is one aspect of care which has been shown to improve clinical outcomes. This study confirms that it will also reduce the cost of treating these complex fractures – underscoring the need for rapid referral and an ortho-plastic setup to handle them. We have only calculated the direct costs of treatment. Infected fractures will also consume extra costs in rehabilitation and absenteeism from later infection recurrence and non-union. Therefore, our estimate of the potential saving is likely to be conservative


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIII | Pages 202 - 202
1 May 2012
Russ M Simm A Leong J Liew S Dowrick A
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The Orthopaedic Unit at The Alfred has been using an external fixator in a novel configuration for protecting lower limb wounds after free flap surgery (sometimes even in the absence of a concomitant bony injury). This soft-tissue frame allows the limb to be elevated without contact so that there is no pressure on the flap and its pedicle. Thus, optimising the arteriovenous circulation. We report our initial experience with these soft tissue frames. The soft tissue frame is not necessarily applied for definitive fracture care, but constructed or modified to optimise elevation of the leg, remove direct pressure from the soft tissues, and stabilise the muscles adjacent to the flap. All ankle-spanning frames held the foot in a plantargrade position to optimise blood flow and recovery (prevent equinus), and minimise intra-compartmental pressure. During 2007, the Plastic Surgery Unit performed 23 free flaps to the lower limbs of 22 patients. Five of these patients had a soft-tissue frame constructed. One patient had a frame applied purely to manage the soft tissue injury, and the other four, who required an external fixator for a bony injury, had their frame modified. Four of the five patients study patients were injured in motor vehicle accidents and one was injured in a simple fall. All five free flaps survived and none required any further surgery. No patients suffered complications (such as bleeding, pin-track infections, or osteomyelitis) related to the soft tissue frame. We strongly recommend considering an external fixator in a modified configuration after lower limb free flap surgery. Constructing a soft tissue frame has no added risks if the fixator is already required. In the case where there is no bony injury, a soft tissue frame has the benefits of providing optimal flap conditions and maintaining anatomical joint alignment. However, this must be balanced against the small risk associated with the insertion of pins (such as infection) and the need for an extra procedure to remove the frame. As always, treatment must be tailored to the individual patient


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_15 | Pages 77 - 77
1 Dec 2015
Williams G Khundkar R Ramsden A Mcnally M
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Chronic osteomyelitis is a challenging clinical problem. Aggressive debridement, bony fixation, obliteration of dead space and vascularised soft tissue coverage with appropriate antimicrobial therapy are essential to successful management of this condition. The gracilis muscle flap is the workhorse flap in our unit for reconstruction of limb osteomyelitis. We describe the experience and use of this flap in our unit over a 3 year period. Clinical records were reviewed from a prospectively-maintained Oxford Free Flap Database and patient notes. All patients who received a free gracilis flap reconstruction as part of the treatment of osteomyelitis between 2011 and 2014 were included in the study. 40 patients received free gracilis flaps; 38/40 for lower limb and 2/40 for upper limb osteomyelitis. Two were myocutaneous flaps, and the remainder were muscle only. The return to theatre rate was 12.5% with a total flap loss rate of 5%. Other flap-specific complications include partial flap loss (2.5%), flap site haematoma (2.5%), donor site haematoma (2.5%) and seroma (2.5%). General complications included pulmonary embolism (2.5%) and death from sepsis (2.5%). All but 2 patients were treated successfully and remain disease free following their initial surgery, with a mean follow up of 12.4 months (range 1–23 months). We have found that the free gracilis muscle flap is effective in the successful treatment of osteomyelitis, with a low complication rate


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 275 - 275
1 Jul 2008
CHANTELOT C FERRY S WAVREILLE G PRODHOMME G GUINAND R FONTAINE C
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Purpose of the study: The latissimus dorsi free flap is widely used for reconstruction of large tissue defects. It is always difficult however to explain the procedure to the patient, particularly the potential sequelae. The purpose of this work was to assess sequelae affecting shoulder function and the esthetic aspect of the harvesting site. Material and methods: We reviewed 16 patients (17 harvestings) aged 37.8 years on average (range 22–62 years), twelve men and four women, at mean follow-up of 4.5 years. All flaps had been harvested to reconstruct tissue defects of the lower limb. Eleven were semi-emergency procedures, four for chronic defects or reconstruction after tumor resection. We assessed the esthetic aspect of the harvesting zone and shoulder function suing Cybex 6000 (comparative isokinetic tests of the two shoulders). The Dash score was noted. Results: Functional impairment was minimum in all patients. The Dash score was 17.5%. (compared with the opposite side was: 27% abduction, 22% extension and 10% rotation. Adduction, flexion and external rotation were preserved. The esthetic aspect was acceptable but not negligible. Obesity appeared to accentuate disgraceful scars. Discussion and conclusion: The latissimus dorsi free flap is often indicated for reconstruction of significant tissue defect. Shoulder function is largely preserved. Patients should be informed about the major scar. The side to be harvested should be discussed with the patient, even in the emergency situation


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 292 - 292
1 May 2006
Giele H Critchley P Gibbons M Athanasou N Jones A
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Aim: To review our series of mid foot sarcomas with regard to excision of tumour, tolerance of radiotherapy and preservation of function. Methods and results: We identified 6 patients with mid foot sarcomas treated in our unit. Synovial sarcoma was the commonest diagnosis. All the patients had stage 1 disease with no evidence of pulmonary metastases at presentation. Patients judged to have resectable tumour but preserving sufficient foot to be functional were spared amputation. They had excision of the sarcoma and immediate reconstruction using fascio-cutaneous free flaps. Complete excision was achieved in all cases. One flap was lost and repeated. In all patients, subsequent radiotherapy was well tolerated without significant complications. All patients remain disease free. All patients have returned to pre-operative functioning including walking and jogging. All except one have returned to work. Conclusion: Patients and feet treated by wide local excision of mid foot sarcomas and reconstructed by free fascio-cutaneous flaps tolerate post-operative radio-therapy well, and return to near normal function


The Bone & Joint Journal
Vol. 100-B, Issue 10 | Pages 1359 - 1363
1 Oct 2018
Chiu Y Chung T Wu C Tsai K Jou I Tu Y Ma C

Aims

This study reports the outcomes of a technique of soft-tissue coverage and Chopart amputation for severe crush injuries of the forefoot.

Patients and Methods

Between January 2012 to December 2016, 12 patients (nine male; three female, mean age 38.58 years; 26 to 55) with severe foot crush injury underwent treatment in our institute. All patients were followed-up for at least one year. Their medical records, imaging, visual analogue scale score, walking ability, complications, and functional outcomes one year postoperatively based on the American Orthopedic Foot and Ankle Society (AOFAS) and 36-Item Short-Form Health Survey (SF-36) scores were reviewed.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 97 - 97
1 May 2011
Fontaine C Wavreille G Bricout J Demondion X Chantelot C
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Fasciae represent a very interesting source of thin, well vascularized soft tissue, which allows gliding of the underlying tendons, especially for coverage of particular anatomical zones, such as the dorsal aspect of the hand and fingers. Some fasciae (such as the fascia temporalis free fiap) have already been used in this way as free fiaps for the coverage of the extremities. The aim of this study was to investigate the blood supply of the posterior brachial fascia (PBF), in order to precise the anatomical bases of a new free fascial fiap.

Our study was based on dissections of 18 cadaveric specimens from 10 formalin preserved corpses. Six upper limbs were used to fictively harvest this fiap

The PBF was thin; its surface was broad, easily separable of the overlying subcutaneous and underlying muscular planes in its upper two thirds. It was richly blood supplied by two main pedicles:

the posterior brachial neurocutaneous branch and

the fascial branch of the upper ulnar collateral artery.

The well vascularized area was 115mm long and 54mm broad in average. These two pedicles were quite constant (respectively 17 cases and 14 cases out of the 18 specimens) and of sufficient caliber to allow microsurgical anastomoses in good conditions. A rich venous network, satellite of the arteries, was always present. An arterial by-pass between both arterial pedicles could spare venous sutures when both arterial pedicles are present and communicating within the fascial depth (13 cases out of 18). Harvesting the fiap was easy through a posteromedial approach in a patient in supine position. The donor site could always be closed and its scare was well acceptable.

The first clinical case is presented in a patient suffering from recurrent tendinous adhesions at the dorsum of the hand after a close trauma with extensive hematoma, after failure of 2 previous tenolyses. After a third tenolysis, the free PBF fiap was performed. The fascia was covered with a free skin graft at day 6. The coverage was nice and the outcome of the tenolysis at 6 month was -15/80 (active motion) and +20/100 (passive motion).


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 241 - 242
1 Nov 2002
Hashmi P
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Reconstruction of large composite tissue defects with expose tendons, neurovascular structures, joints and bones is difficult and challenging problem. Such difficult situations can be handled in a single stage with free tissue transfer provided microsurgical expertise is available. A review of 12 cases of free scapular flap is being presented, performed over period of 20 months from December 97 to July 1999. Free scapular flap is based on transverse branch of circumflex scapular artery, which is branch of subscapular artery. All the patients in this series were male, with average age of 29 years. The mechanism of injury leading to tissue defects was, RTA 7 cases, industrial accidents 3 cases and bomb blast injury 2 cases. The various sites requiring free scapular flaps were, plantar aspect of foot, heel and leg in 5 cases, dorsum of hand, first web space and forearm in 3 cases, axilla and upper arm in 2 cases and one each for popliteal fossa and dorsum of foot. Only 4 cases presented to AKUH within 6 hours of injury while remaining 8 cases had prior treatment somewhere else and subsequent polymicrobial infection. In three cases, 2-3 debridements were done before coverage with free flap. Average defect size was 18cm long and 11cm wide. All of these cases had associated fracture. Free scapular flap is very robust flap with long vascular pedicle and large lumen artery, which can be anastomosed very easily. Donor site is closed primarily without any morbidity and scar is hidden. Scapular flap can be considered as workhorse for extremity defects


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 156 - 156
1 Mar 2009
Tos P Conforti L Battiston B
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Surgical treatment of complex wounds of the lower extremities has greatly evolved in the last years, leading to a higher percentage of limb salvage and good functional recovery.

Microsurgery surely is a good weapon when facing extensive tissue losses and infections.

From 1994 to 2004, 25 patients have been treated in our department for complex traumas of the lower limb.

These cases include 4 acute complex injuries with extensive soft tissue loss (Gustilo III open fractures) which were treated with 3 Latissimus Dorsi and 1 Gracilis Muscle Flaps; 10 delayed referrals with exposed bone or bony/soft tissue loss (1 Fibula Flap for the distal femur, 1 Fibula Flap for the lower leg, 3 cases of amputation stump coverage, 2 Parascapular Flaps, 2 Gracilis Flaps, 1 Latissimus Dorsi Flap, 1 Serratus Flap with a rib, 1 Iliac Crest Flap); and 11 late reconstructions of chronic osteomyelitis: 1 distal femur infection (Double-barrel Fibula Flap), 10 infections of the middle or distal third of the lower leg (3 Fibula Flaps, 4 Latissimus Dorsi Flaps, 3 Gracilis Muscle Flaps).

In the last few years, the approach to bony tissue losses has been changing: on one hand, elongation techniques for the lower extremity give good results; on the other, microsurgery may allow a single-stage reconstruction of bone, muscle and skin defects, leading to much shorter hospitalization time, and improvement of the patients’ quality of life because of a faster recovery.

Over 90% of the flaps survived, leading to a good recovery of the patients. The two failures were due to the necrosis of a Gracilis Flap in the coverage of an amputation stump and that of a Latissimus Dorsi Flap used for an extensive soft tissue loss in a leg which subsequently had to be amputated.

In 78.5% of the cases of osteomyelitis recovery was obtained after a single operation, and in only 12.3% of the cases the flaps had to be partially revised.

In 2 cases, after the bony resection and coverage by means of a Gracilis Muscle Flap, a homolateral fibular transfer with the Ilizarov technique was performed.

The length of bone resections treated by fibular flaps was 8–12 cm (mean 9).


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 358 - 358
1 Mar 2004
Kuokkanen H Tukiainen E
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Aims: In some severe lower limb injuries, the level of bone trauma enables preservation of knee joint only if the soft tissues can be reconstructed over the exposed bone. The options for soft-tissue reconstruction of an amputation stump are to use a ßap from the amputated distal part, a local ßap possibly after tissue expansion or a free ßap. Methods: To preserve an adequate length of stump we reconstructed 10 stumps with latissimus dorsi free ßaps: above the knee in one and below the knee in nine. The reconstructions were done during the acute post-traumaic phase in þve and for late problems with the stump in four patients. In one patient the reconstruction was done nine weeks after a below-knee amputation for ischaemic necrosis after septicaemia. Results: All ßaps survived, but the venous anastomosis had to be revised in three patients in the early post-operative period. All patients regained adequate ambulation for their daily activities. The ßap was secondarily debulked in three patients. Conclusions: Every effort should be made to preserve an adequate stump length, particularly in young patients with crushing injuries of the extremities and when there is severe or recurrent late stump ulceration. A latissimus dorsi musculocunaeous soft-tissue reconstruction is reliable and durable option for stump defects.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 41 - 41
1 Jan 2017
Benassarou M Pazart L Gindraux F Meyer C
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Reconstructing mandibular and maxillary bone defects with free vascularized bone flaps requires to take into account the aesthetic and functional requirements to consider subsequent placement of dental implants. It implies a three-dimensional conformation of the bone fragment. This is usually done by making osteotomies on the bone harvested. The aim of our study was to evaluate the interest of virtual planning and 3D printing using free software and a consumer printer in this indication. Invesalius® software (Technology of Information Renato Archer Center, Campinas, Brazil) was used to build virtual models from the patients' CT scan imaging data. The surgical procedure was planned using Meshmixer® (Autodesk, San Rafael, United States). Meshlab® software (Visual Computing Lab, Pisa, Italy) was used to design cutting guides for the flap harvest and modelling. 3D printing of these guides with a consumer printer (Ultimaker 2® Ultimaker B.V., Geldermalsen, the Netherlands) allowed the transfer of the planning to the operating room. Three patients requiring mandibular reconstruction underwent an iliac crest free flap, a fibula free flap and a scapula free flap, and could benefit from this technique. In each case, the bone resection was performed virtually and the positioning of the bone available at the donor site was simulated on screen. This allowed to anticipate the position and orientation of the cutting planes on the bone flap. From the anatomy of the donor site and the cutting planes, harvest templates and cutting guides could be designed by computer. Planning the conformation of the bone flap to the recipient site has allowed an anatomical, aesthetic and functional reconstruction of the bone defect. Surgeon-made virtual planning and “low cost” 3D printing helps harvest the bone flap and position and orient the osteotomies to adapt it to the defect. They provide, both the patient and the surgeon, reduced operative time and better anticipation of the result, particularly in the context of the maxillofacial reconstruction. Compared to commercially available custom-made devices, this technique allows the manufacture of the guides without delay and at a cheap price


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 44 - 44
1 Jan 2004
Chantelot C Aihonnou T Gueguen G Migaud H Fontaine C
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Purpose: Management of extensive tibial loss raises the question of indications for vascularised grafts. These techniques depend on the number of functional vascular trunks available. We developed a modified technique which allows using this type of graft without sacrificing the tibial pedicle, making it usable when only one trunk remains functional. We use the fibular arterial supply to bridge the remaining axis. The purpose of this work was to detail the modalities of this technique and provide early results.

Material and method: Since 2000, we have reserved this technique for infected nonunion with loss of tibial tissue extending over 5 cm in patients who decline amputation. Four patients (four men, mean age 30 years) underwent the procedure. The initial trauma resulted from a motorcycle (n=3) or firearm (n=1) accident. The patients were referred to our unit within three months on the average. Prior treatments (cancellous graft in an open or intrafocal procedure) had failed in all patients who presented persistent infection. Antibiotics were administered until bone healing in all patients. Mean length of the gap was 10 cm (7 – 15 cm). The composite graft (skin and fibula with a vascularised fibular bundle) was raised from the contralateral limb and cross-leg anastomosed proximally and distally on the receiver anterior tibial bundle (all four cases).

Results: All fractures consolidated between six and twelve months after initiating management of this technique. Bone and soft tissue losses healed without shortening. There were not repeated fractures after mean follow-up of twelve months (range eight months to two years). No complementary bone graft was necessary. Infection resolved in all patients.

Discussion and conclusion: As for classical vascularised fibula grafts, this technique enables controlling bone and soft tissue problems together (composite graft). The graft is vascularised favouring antibiotic diffusion. The mechanical quality is better than with a pure cancellous graft but longer follow-up would be required to determine the rate of repeated fractures. This technique broadens indications for vascularised fibula grafts which can be used in unfavourable vascular contexts where only one or two leg trunks persist.


The Bone & Joint Journal
Vol. 97-B, Issue 2 | Pages 215 - 220
1 Feb 2015
Soons J Rakhorst HA Ruettermann M Luijsterburg AJM Bos PK Zöphel OT

A total of seven patients (six men and one woman) with a defect in the Achilles tendon and overlying soft tissue underwent reconstruction using either a composite radial forearm flap (n = 3) or an anterolateral thigh flap (n = 4). The Achilles tendons were reconstructed using chimeric palmaris longus (n = 2) or tensor fascia lata (n = 2) flaps or transfer of the flexor hallucis longus tendon (n = 3). Surgical parameters such as the rate of complications and the time between the initial repair and flap surgery were analysed. Function was measured objectively by recording the circumference of the calf, the isometric strength of the plantar flexors and the range of movement of the ankle. The Achilles tendon Total Rupture Score (ATRS) questionnaire was used as a patient-reported outcome measure. Most patients had undergone several previous operations to the Achilles tendon prior to flap surgery. The mean time to flap surgery was 14.3 months (2.1 to 40.7). At a mean follow-up of 32.3 months (12.1 to 59.6) the circumference of the calf on the operated lower limb was reduced by a mean of 1.9 cm (. sd. 0.74) compared with the contralateral limb (p = 0.042). The mean strength of the plantar flexors on the operated lower limb was reduced to 88.9% of that of the contralateral limb (p = 0.043). There was no significant difference in the range of movement between the two sides (p = 0.317). The mean ATRS score was 72 points (. sd. 20.0). One patient who had an initial successful reconstruction developed a skin defect of the composite flap 12 months after free flap surgery and this resulted in recurrent infections, culminating in transtibial amputation 44 months after reconstruction. . These otherwise indicate that reconstruction of the Achilles tendon combined with flap cover results in a successful and functional reconstruction. Cite this article: Bone Joint J 2015;97-B:215–20


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 385 - 385
1 Sep 2005
Segev E Wientroub S Amir A Gur E
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Background: The treatment of extensive soft tissue injury with bony involvement due to orthopaedic trauma or other pathologic conditions has undergone great improvement in the last decade. The main fields that assisted with that progress are: the ability to transfer autogenous vascularized soft and/or bony tissues to the injured areas and the possibility to apply external fixation either statistically for acute stabilization of a limb or using dynamic frames to correct late occurring contractures or deformities. Objectives: To present our experience in treating young patients with severe, post traumatic or tumor resection soft tissue and bony injuries including bone loss and late joint contractures. That was treated by a combination of free vascularized flaps and static or dynamic circular external fixation with special emphasis on preplanning and technical issues critical for the success of such complex procedures. Methods: Seven patients were included in the study; six post traumatic patients who received free vascularized myocutaneous latissimum dorsi or fasciocutaneous anterolateral thigh flaps to the calf and foot. All six patients had an Ilizarov frame for initial stabilization; two of them needed late dynamic correction of equines with the frame. The seventh patient had surgery for removal of osteosarcoma and received a vascularized osteocutaneous fibula flap with fixation by Ilizarov frame, this patient also needed late dynamic frame application for equines correction. Results: The mean age at surgery was 11.6 years (range 7–14 years); mean follow up was 1.8 years (range 2 months – 3.4 years). All microvascular flaps but one survived where the patient with the failed latissimus dorsi flap had the second muscle transferred at the next day. One patient needed 2 vascular revisions. All bone flap showed solid union at 3 months post operatively. Four patients achieved plantigrade foot initially. The three patients with dynamic correction achieved plantigrade foot at frame removal. Complications: Equinus contracture of the ankle in three patients, injury to the vascular anastomosis in one patient. Pin tract infection in all patients that responded well to antibiotics. Conclusions: The circular external fixator is a reliable method for initial fixation of injured limb. It is advised to apply the fixator before the transfer of the free flap. Position of the fixation pins should be discussed before hand with the plastic surgeons to allow free access to the microvascular anastomosis site. Free flaps allow the coverage of large soft tissue defects while the external fixators maintain anatomical position of the limb. Late occurring contractures after the incorporation of the flap can be safely corrected gradually with the circular frame. It is of paramount importance to include the foot in the frame and maintain neutral position of the ankle joint to prevent equines contractures


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 543 - 544
1 Nov 2011
Falcone M Wavreille G Fontaine C Chantelot C
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Purpose of the study: This retrospective study evaluated the results, complications and sequelae of 22 free fibular flaps used for bone reconstructions of the limbs assessed at mean 44.4 months. Material and methods: The tissue loss was the result of trauma in 20 patients and followed cancerology surgery in two. The localisations involved the upper limb in 15 patients and the lower limb in seven. Mean length of bone loss was 11.1 cm. Six injuries required skin cover in addition to the fibular flap. Five patients had had a cement spacer. Fixation methods were: internal fixation (n=14) and external fixation (n=8). Classical vessel anastomosis (one vein, one artery) was used in eight patients and a bridge method (recipient site artery by a fibular artery) in 14 patients. Results: Bone healing was achieved in 15 patients in 6.7 months on average. Healing was secondary in four patients after corticocancellous grafting. Three flaps failed. Factors significantly associated with favourable healing were: long time from trauma to flap repair, small size of the initial skin opening, first-intention Masquelet, internal fixation, and first-intention cancellous autologous graft. Early postoperative complications of the recipient site included two haematomas and three superficial skin deficiencies. Two graft fractures occurred in one patient and healed after orthopaedic treatment. There were few donor site problems: two early haematomas and two retractions of the flexor hallucis longus. Mean morbidity scores revealed very good results: 1.23/16 with the Point Evaluation System, 93.16/100 for the Karlsson score, and 94.29100 for the Kitaoka score. Globally, the functional assessment of the fibular flap was excellent for three patients, good for eleven, fair for four and poor for one. Discussion: Our healing rates and durations were not statistically different from earlier reports in the literature. We focused on rigorous preparation in terms of debridement and antibiotic therapy, insertion of a spacer, internal fixation, and complementary first-intention autologous bone graft. In addition, we propose a bridging anastomosis which simplifies the technique and gives the same results as the classical anastomosis methods