We reproduced a frequently cited study performed at our University Hospital that was published in the British Medical Journal in 1981 assessing the extent of “snow and ice” fractures during the winter period. As per the original study, four days of snow and ice were identified as well as two control periods when snow and ice wasn't recorded; four days within the same year, with a similar amount of sunshine hours, and four days one calendar year later. The distribution of fractures according to age and sex in addition to the anatomical location were examined in relation to the presence of snow and ice as well as comparisons with the index study 33 years ago.Background
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Background. North America is facing a rising
Given the function of adiponectin (ADIPOQ) on the inflammatory condition of obesity and osteoarthritis (OA), we hypothesized that the ADIPOQ gene might be a candidate gene for a marker of susceptibility to OA. We systematically screened three tagging polymorphisms (rs182052, rs2082940 and rs6773957) in the ADIPOQ gene, and evaluated the association between the genetic variants and OA risk in a case-controlled study that included 196 OA patients and 442 controls in a northern Chinese population. Genotyping was performed using the Sequenom MassARRAY iPLEX platform.Objectives
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