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Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 227 - 227
1 Nov 2002
Yu T Chien** J Chen I
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Materials and Methods: This study included careful analysis of 24 knees with polyethylene wear in which revision surgery was performed. Preoperative evaluations included (1) single-leg standing AP, lateral and stress view, (2) dynamic weight-bearing lateral radiographs, and (3) manual test under anesthesia. Intraoperatively, (1) morphologic change of the worn inserts, (2) rotational alignment of tibia-femoral articulation (3) motion behavior of the joint following trial insertion was observed. Based on the above evaluation, 20 knees were revised with 3-component revision by constrained PS knees. The remaining 3 knees received isolated insert exchange.

Results: During the follow-up of 2–6 years, good and excellent results were obtained in all 21 patients who received three-component revision with Osteonics series IV constrained PS prosthesis. The mean HSS score was 92 and the mean ROM was 112 degrees. In the three patients receiving exchange of a thicker polyethylene only, two failed with the same mechanism 15 months and 23 months later and received re-revision. The X-ray of the remaining patient at 5-year F/U revealed impending failure.

Discussion: Based on our preoperative plain/dynamic radiographs and intraoperative findings, we postulate that tibial polyethylene wear is attributed to retained PCL in the absence of ACL, excessive posterior slope of tibial cut, rotational mismatch of tibia-femoral rotation and abnormal condylar lift-off in weight-bearing phase. With passage of time and progression of wear, secondary ligamentous decompensation and multidirectional instability may develop as a result of abnormal kinematics. Therefore, by isolated exchange of insert, the failure mechanism remains unchanged and secondary ligamentous instability persists. Eventually the new insert will fail again.

Conclusion: In revision surgery of tibial polyethelene wear, both the primary cause of failure and the secondary ligamentous instability must be addressed. The author strongly advocate that, in addition to reversal of the primary failure mechanism by 3-component revision, the use of a constrained PS prosthesis is mandatory to overcome the secondary soft tissue decompensation.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 245 - 245
1 Mar 2004
Ridgeway S Tai C Carey-Smith R Graevett-Ball C Harrison H
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Aims: To investigate the functional outcome with different autologous bone graft weights in posterolateral lumbar spine instrumentation for DSD’s. Methods: A total of 79 patients (mean age of 47.2) with chronic lower back pain for at least 2 years, with at least 1 year of failed conservative treatment and who were undergoing pos-terolateral spinal instrumentation for DSD’s were admitted to the trial. Patients were randomised into three groups to receive bone graft weights of 25g (Group A=26 patients), 50g (Group B=30 patients) and 100g (Group C=23 patients) per segment. Pain, clinical characteristics, disability (Oswestry), radiographic fusion, patient satisfaction and complications were recorded at 3, 6, 12 and 24-month follow-ups. Results: At 2 years, Group B (50g) had a significantly improved Oswestry Index, pain intensity, motor and sensory changes, and overall patient satisfaction than Group C (100g), which was significantly better than Group A (25g). There was no correlation between bone graft weight and radiographic fusion, between fusion and outcome, nor smoking and fusion or bone graft weight. Complications were similar. Conclusions: Patients had significantly better functional and clinical outcomes with bone graft weights of 50g. Bone graft weights of 25g had the worse outcomes and 100g did not seem to have any beneficial affect over 50g. We recommend autologous bone graft weights of 50g per fused spinal segments in this group of surgical patients.


The Bone & Joint Journal
Vol. 104-B, Issue 5 | Pages 627 - 632
2 May 2022
Sigmundsson FG Joelson A Strömqvist F

Aims

Lumbar disc prolapse is a frequent indication for surgery. The few available long-term follow-up studies focus mainly on repeated surgery for recurrent disease. The aim of this study was to analyze all reasons for additional surgery for patients operated on for a primary lumbar disc prolapse.

Methods

We retrieved data from the Swedish spine register about 3,291 patients who underwent primary surgery for a lumbar disc prolapse between January 2007 and December 2008. These patients were followed until December 2020 to record all additional lumbar spine operations and the reason for them.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 527 - 528
1 Aug 2008
Lakkireddi MP Gill MI Panjugala DHC Tonsley MR Marsh MG
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Patients had traditionally relied on health care professionals for advice and treatment options for most orthopaedic conditions including degenerative lumbar spine disease. However the unprecedented access to heath care information offered by the internet is changing the way how patients gather information and make treatment choices. Aims & Methods: The purpose of this study was to determine the influence of the internet on patients presenting to orthopaedic clinics with degenerative lumbar spine disease and its influence on decision making. A power calculation was done to determine appropriate sample size needed for the study. Questionnaires were handed to willing patients who were attending back clinic for more 6 months and diagnosed to have degenerative lumbar spine disease. Each participant filled a 25 point survey and a total of 105 surveys were collected. Results: Out of the 79% who had access to the internet, 55% accessed it from home which is in comparison to the national statistics of 57%. The rest of 24% access internet at other places. Internet usage was found to be directly proportional to education and earnings with 100% in professionals and then dropping significantly. 80% living in urban areas used internet to access health information. Topics commonly searched include causes (74%), symptoms (70%), treatment/surgical options (82%). Only few people looked at the choice of surgeons (30%) and hospitals (30%) as the practice is mostly NHS based. Around 50% made clinical decisions based on their search. 86% used general search engines like yahoo, google, 14% used sites like med line, NHS. UK. Health professionals had more influence in decision making than internet (80%). Conclusions: Internet is evolving as a powerful source of health information and influencing more an more patients in clinical decision making with a 5% growth in internet usage every year (national statistics)


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 145 - 145
1 Apr 2012
Mahir S Marsh G Lakkireddi P
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The purpose of this retrospective study, is to demonstrate the survivorship and clinical effectiveness of the Wallis implant, against low back pain and functional disability in patients with degenerative lumbar spine disease. The Wallis Interspinous implant, was developed as a minimally invasive and anatomically conserving procedure, without recourse to rigid fusion procedures. The initial finite element analysis and cadaver biomechanical studies showed that the Wallis ligament improves stability in the degenerate lumbar motion segment. Unloading the disc and facet joints reduces intradiscal pressures at same and adjacent levels allowing for the potential of the disc to repair itself. A total of 157 patients who had wallis ligament insertion between 2003 and 2009 were reviewed, with a mean age of 54 and were followed for 48 months on average. Patients were assessed pre-operatively and post-operatively every 6 months by VAS pain score, Oswestry Disability Index and SF-36. 90% of patients improved, to show a minimal clinical difference, compared to the pre-operative evaluation. There is overall 75-80% good clinical outcome. Low infection rate of 1.1%. Two cases of prolapsed discs at the same level requiring further discectomy, 7 required fusion. No fractures or expulsions. The Wallis implant represents a safe non-fusion stabilisation device in the treatment of degenerative lumbar spine disease with canal stenosis. There is less soft tissue damage, quick rehabilitation, less morbidity and associated low complication rate


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 528 - 528
1 Aug 2008
Lakkireddi MP Gill MI Chan MJ Trehan MR Kotrba D Marsh MG
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Background: The Wallis Interspinous implant was developed as a minimally invasive and anatomically conserving procedure without recourse to rigid fusion procedures. The initial finite element analysis and cadaver biomechanical studies showed that the Wallis ligament improves stability in the degenerate lumbar motion segment. Unloading the disc and facet joints reduces intradiscal pressures at same and adjacent levels allowing for the potential of the disc to repair itself. Aims & Methods: The purpose of this prospective study is to demonstrate the survivorship and clinical effectiveness of Wallis implant against low back pain and functional disability in patients with degenerative lumbar spine disease. Patients were assessed pre operatively and post operatively every 6 months by VAS pain score, Oswestry Disability Index, SF-36. All the patients had pre operative radiographs, MRI scans and followed up with interval radiographs. The results were assessed in three sub groups. Group-1 is decompression and stabilisation, group-2 is stabilisation alone, and group- 3 is “Topping off” a fusion. Results: A total of 211 Wallis Ligaments were inserted in 203 patients between July 2003 and November 2006. In total 179 patients were reviewed with mean age of 54(24–85) were followed for an average 30 months (6–40). The most common level is L4/5 (59%) followed by L3/4. In all the subgroups pain scores and oswestry disability index improved by 50%. And similarly SF-36 scores improved. There is 75–80% good clinical outcome with a survivorship of 98–99%. Low infection rate of 1.1%. Two cases of prolapsed discs at the same level requiring further discectomy and one case of iatrogenic L4 paraesthesia. Conclusions: The Wallis ligament represents a successful non fusion alternative in treatment of degenerative lumbar spine disease with least soft tissue damage, quick rehabilitation, less morbidity and associated low complication rate. The Wallis implant treats pain, preserves mobility, anatomy and stability while being fully reversible, therefore leaving all subsequent options open


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 151 - 151
1 Mar 2006
Schuetz U Richter M Dreinhoefer K Puhl W Koepp H
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Introduction: Analgesia from controlled injections of local anaesthetic into the lumbar zygapohysial joint (z-joint) has been accepted as the standard for diagnosis of z-joint pain. Little is known about the placebo-response rate. Aim of this pilot study is to validate the fluoroscopically controlled z-joint-injection (ZJI) as an instrument for diagnosis of degenerative symptomatic z-joint disease. Material and Methods: Due to degenerative lumbar spine syndrome 50 z-joints (L5/5: 27; L5/S1 23) were injected three times in a single blinded trial bilaterally. According to a randomisation protocol, using the oblique needle technique the ZJI were done with an local anaesthetic (LA: 1.5 ml 0.5% Scandicain), a saline placebo (sodium: 1.5ml 0.9% NaCl) and with no agent (sicca punction). The pain level before and after the injections (30 min, 1 and 2–3 hours) was documented by the patient on a 10pts.-VAS. Improvement in the pain level after an FJI is defined as responder. A responder reacts false positive if the degree of effectiveness of the placebo-FJI is the same or better than the response to LA. A patient reacts false negative if the pain diminution after LA application is lower than after placebo. Results: Preliminary results regarding the reactions 30 min after injection are presented. 26% were non-responder and 52.9% LA-responder. The sicca response rate was 38%, for sodium it was 46%. Reaction after sicca-FJI was false positive in 24%, after sodium-FJI in 32% of cases. 38% reacted false negative to LA-injection. The order of the agent application didn’t have significant influence on the responder rates and also not on the extent of contradictory effects. Conclusions: Despite numerous examinations none could sufficiently evaluate accurate reliable predictors for positive ZJI-responders till now. This is confirmed by our high LA-non-responder-rate of 48.1%. However, only a placebo injection can absolutely exclude a true placebo response. Placebo responses seem to be common. High specificity (minimization of the false positive results) and sensitivity (minimization of the false negative results) are characters for a good diagnostic test. In literature, the specificity of the intraarticular facet block as a diagnostic test for facet joint disease is currently unknown. Capsular rupture with epidural and periarticular diffusion is probably responsible for many false positive findings. Regarding our results, the validity of only one ZJI is not acceptable and shouldn’t be consulted as a diagnostic method for the identification of a facet joint syndrome, therefore. Pain relief after ZJI is a poor predictor of clinical outcome of posterolateral lumbosacral fusions when based on single blocks. Corresponding further examinations are necessary also regarding the ZJI-reliability


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 265 - 265
1 Mar 2004
Marttinen I Neva M Paakkala T Vihtonen K
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Aims: To evaluate the outcome of surgery in patients with lumbar spine degenerative disease or isthmic spon-dylolisthesis. Methods: Lumbar spine fusion with or without decompression was performed in 132 consecutive patients. Altogether 115 patients attended to follow-up an average 3.4 years after operation. The overall result was assessed by the patient and by an independent observer. Moreover, the disability was measured using Oswestry questionnaire and fusion rate was assessed from flexion and extension radiographs. Results: The complications of surgery were: misplacement of screws in 2 patients, paresis of peroneal nerve in 1 patient, superficial wound infection in 4 patients, breakage of fixation device in 1 patient and spinal fluid fistulas in 2 patients. According to patient’s own opinion the result of surgery was excellent, good or fair in 86 percent of the patients and even 89.6% of them benefited from the surgery. The average postoperative Oswestry score was 28. According to radiographs the fusion rate was 93 percent. At the time of operation 40 patients were retaired and 66 (93%) out of the 75 patients who were still at working age returned to work. Conclusion: Lumbar spine fusion is an effective and safe treatment of degenerative lumbar spine disease and isthmic spondylolisthesis. However, the careful selection of patients is an important factor for success


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_15 | Pages 26 - 26
1 Oct 2014
Molloy S Butler J Yu H Sewell M Benton A Selvadurai S Agu O
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To assess implant performance, to evaluate fusion and to assess clinical and radiologic outcome of circumferential fusion using porous tantalum cages for ALIF in a 360-degree fusion. A retrospective cohort study was performed over a 4-year period that included the implantation of 280 tantalum cages in 98 patients by the technique of anterior lumbar interbody fusion (ALIF) and posterolateral spondylodesis. Radiographic follow-up was performed to document any implant related problems. Preoperative and postoperative clinical outcome measures were assessed. No neurological, vascular or visceral injuries were reported. There were no rod breakages and no symptomatic non-unions. One revision procedure was performed for fracture. Mean VAS back pain score in our patient cohort improved from 7.5 preoperatively to 1.9 at latest follow-up, mean VAS leg pain score improved from 6.2 to 1.1 and mean ODI score improved from 51.1 to 18.3. Porous tantalum cages have high strength and flexibility, in addition to having similar biomaterial properties to cancellous bone. Their use in 360-degree spondylodesis to treat degenerative lumbar spine deformity has been demonstrated to be very safe and effective, with excellent clinical and functional outcomes


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_13 | Pages 40 - 40
1 Dec 2022
Dandurand C Mashayekhi M McIntosh G Street J Fisher C Jacobs B Johnson MG Paquet J Wilson J Hall H Bailey C Christie S Nataraj A Manson N Phan P Rampersaud RY Thomas K Dea N Soroceanu A Marion T Kelly A Santaguida C Finkelstein J Charest-Morin R
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Prolonged length of stay (LOS) is a significant contributor to the variation in surgical health care costs and resource utilization after elective spine surgery. The primary goal of this study was to identify patient, surgical and institutional variables that influence LOS. The secondary objective is to examine variability in institutional practices among participating centers.

This is a retrospective study of a prospectively multicentric followed cohort of patients enrolled in the CSORN between January 2015 and October 2020. A logistic regression model and bootstrapping method was used. A survey was sent to participating centers to assessed institutional level interventions in place to decrease LOS. Centers with LOS shorter than the median were compared to centers with LOS longer than the median.

A total of 3734 patients were included (979 discectomies, 1102 laminectomies, 1653 fusions). The median LOS for discectomy, laminectomy and fusion were respectively 0.0 day (IQR 1.0), 1.0 day (IQR 2.0) and 4.0 days (IQR 2.0). Laminectomy group had the largest variability (SD=4.4, Range 0-133 days). For discectomy, predictors of LOS longer than 0 days were having less leg pain, higher ODI, symptoms duration over 2 years, open procedure, and AE (p< 0.05). Predictors of longer LOS than median of 1 day for laminectomy were increasing age, living alone, higher ODI, open procedures, longer operative time, and AEs (p< 0.05). For posterior instrumented fusion, predictors of longer LOS than median of 4 days were older age, living alone, more comorbidities, less back pain, higher ODI, using narcotics, longer operative time, open procedures, and AEs (p< 0.05). Ten centers (53%) had either ERAS or a standardized protocol aimed at reducing LOS.

In this study stratifying individual patient and institutional level factors across Canada, several independent predictors were identified to enhance the understanding of LOS variability in common elective lumbar spine surgery. The current study provides an updated detailed analysis of the ongoing Canadian efforts in the implementation of multimodal ERAS care pathways. Future studies should explore multivariate analysis in institutional factors and the influence of preoperative patient education on LOS.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVIII | Pages 45 - 45
1 Jun 2012
Russell D Behbahani M Alakandy L
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Pedicle screw fixation is an effective and reliable method for achieving stabilization in lumbar degenerative disease. The procedure carries a risk of violating the spinal and neural canal which can lead to nerve injury. This audit examines the accuracy of screw placement using intra-operative image guidance.

Retrospective audit of patients undergoing lumbar pedicle screw fixation using image guidance systems over an 18-month period. Case records were reviewed to identify complications related to screw placement and post-operative CT scans reviewed to study the accuracy of screw position.

Of the 98 pedicle screws placed in 25 patients, pedicle violation occurred in 4 screw placements (4.1%). Medial or inferior breach of the pedicle cortex was seen in 2 screws (2%). Nerve root injury as a consequence of this violation was seen in one patient resulting in irreversible partial nerve root dysfunction. Mean set up time for the guidance system was 42 minutes. The mean operative time was 192 minutes.

Violation of either the medial or inferior pedicle cortex during placement of fixation screws is a rare, but potentially serious complication bearing lasting consequences. Image-guided placement can be helpful and possibly improve accuracy; particularly in patients with distorted spinal anatomy.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 272 - 272
1 Jul 2011
Bederman SS Mahomed NN Kreder HJ McIsaac WJ Coyte PC Wright JG
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Purpose: Surgery for degenerative lumbar spinal conditions offers tremendous benefit for patients with moderate/severe symptoms failing non-operative treatment. There is little appreciation among referring family physicians (FPs) on factors that identify the ideal surgical candidate. Differences in preferences between patients and physicians leads to wide variation in referrals and impedes the shared decision-making process. Our purpose was to identify the dominant clinical factors influencing patient, FP, and surgeon preferences for lumbar spinal surgery.

Method: We used conjoint analysis, a rigorous method for eliciting preferences, in a mailed survey to all orthopaedic and neurosurgeons, a random sample of FPs, and patients in Ontario to determine the importance that respondents place on decisions for lumbar spinal surgery. We identified six clinical factors (walking tolerance, duration of pain, pain severity, neurological symptoms, typical onset, and dominant location of pain) and presented 16 hypothetical vignettes to participants who rated, on a six-point-scale, their preference for surgery. Data were analyzed using random-effects ordered probit regression models and relative importance of each clinical factor was reported.

Results: We obtained responses from 131 surgeons, 202 FPs, and 164 patients. We demonstrated that despite wide variations in overall responses, all six clinical factors were highly associated with surgical preference (p< 0.01). Surgeons placed the highest importance on the location of pain (34%), followed by pain severity (19%) and walking tolerance (19%). FPs considered neurological symptoms (23%), walking tolerance (20%), pain severity (20%), and typical onset (16%) to all be of similar importance. Pain severity (29%), walking tolerance (29%), and duration of pain (28%) were the most important factors for patients in deciding for surgery. Orthopaedic (over neurosurgical) specialty was statistically associated with a lower preference for surgery (p< 0.047). Older patient age (p< 0.03) and previous surgical consultation (p< 0.03) were both associated with a greater patient preference for considering surgery.

Conclusion: Different preferences for surgery exist between surgeons, FPs and patients. FPs may reduce over- and under-referrals by appreciating surgeons’ importance on location of pain (leg versus back). Surgeons and FPs may improve the shared decision making process by understanding that patients place high importance on duration, severity, and walking tolerance.


The Journal of Bone & Joint Surgery British Volume
Vol. 79-B, Issue 6 | Pages 1042 - 1042
1 Nov 1997
Mulholland RC


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_2 | Pages 10 - 10
1 Feb 2015
Manara J Bowey A Walton R Vishwanathan K Braithwaite I
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Aim

To use Patient Reported Outcome Measures (PROMs) to determine the effectiveness of lumbar spinal surgery at a single UK institution.

Methods

Consecutive patients who underwent lumbar spinal surgery (discectomies or decompressions) from 1 January 2011 to 13 March 2013 at a UK District General Hospital were assessed. The procedures were performed or supervised by a senior Consultant Orthopaedic spinal surgeon. All patients completed PROM questionnaires before and three months following surgery. These included Visual Analogue Scores (VAS), SF-12, Oswestry Disability Index (ODI) and Roland Morris Low Back Pain Questionnaire (RMQ).


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 339 - 339
1 May 2010
Ramirez M Montes A Gonzalez G Salo G Molina A Llado A Soler E Cáceres E
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Background: Control of acute postoperative pain remains a serious problem. Postoperative pain is associated with an increase in thrombotic or respiratory complications. In the other hand the association between surgery, acute postoperative pain and ongoing chronic pain is well defined.

Target: To evaluate the incidence of severe pain after surgery for degenerative lumbar pain, with two analgesic techniques; intravenous analgesia (i.v.) (group 1) and patient controlled analgesia (PCA) (group 2).

Study design: Retrospective study with dates obtains prospectively.

Patient sample: We studied 206 patients operated between january 04 and june 05. Group 1 (intravenous) 80 patients and 126 in group 2 (PCA).

Outcomes mesasures: Percentage of patients with severe pain, number of rescues and complications.

Materials and methods: The type of postoperative analgesia administrated was decided by the anaesthesiologist. To measure pain intensity the VAS was assessed every 6 hours and worst score was used, excluding recovery room. Type of rescue analgesia was the same in all patients and these was recommended in VAS > 3. We evaluate sex, age and comorbidity by ASA. We have defining analgesic ‘failure’ by the overall incidence of pain intensity in two categories: the percentage of patients who experienced moderate-severe pain (VAS > 3) and severe pain (VAS> or = 7). As the pain scores were not normally distributed we not used mean and SD of VAS. The number of rescues and complications were also evaluated.

Results: There was not differences in median age (group 1 50’85 sd 15’4; group 2 52’44 sd 15’4 p=0’47), ASA (group 1 1’89 sd 0’75; group 2 1’90 sd 0’57 p=0’88) or diagnosis between two groups. There were differences in percentages of sexes, group 1 with 40% of women and 62’69% in group 2 (p=0’013). There were not differences in incidence of patients with moderate-severe pain (group 1 15/80; group 2 30/126. p=0’392) neither in incidence of patients with severe pain (group 1 33/80; group 2 51/126. p=0’912). There were not differences in number of rescues (p=0’912) neither in number of complications between groups. Global incidence of VAS > 3 were 40’8 but the incidence of rescues were 25’2%

Conclusions: Our findings suggest that both techniques have similar effectiveness, although the global incidence of severe pain was not optimal (21’8%). It is important to remark the different between incidence of patients with VAS > 3 and number of rescues administrated.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_14 | Pages 38 - 38
1 Dec 2022
Tedesco G Evangelisti G Fusco E Ghermandi R Girolami M Pipola V Tedesco E Romoli S Fontanella M Brodano GB Gasbarrini A
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Neurological complications in oncological and degenerative spine surgery represent one of the most feared risks of these procedures. Multimodal intraoperative neurophysiological monitoring (IONM) mainly uses methods to detect changes in the patient's neurological status in a timely manner, thus allowing actions that can reverse neurological deficits before they become irreversible. The utopian goal of spinal surgery is the absence of neurological complications while the realistic goal is to optimize the responses to changes in neuromonitoring such that permanent deficits occur less frequently as possible. In 2014, an algorithm was proposed in response to changes in neuromonitoring for deformity corrections in spinal surgery. There are several studies that confirm the positive impact that a checklist has on care. The proposed checklist has been specifically designed for interventions on stable columns which is significantly different from oncological and degenerative surgery. The goal of this project is to provide a checklist for oncological and degenerative spine surgery to improve the quality of care and minimize the risk of neurological deficit through the optimization of clinical decision-making during periods of intraoperative stress or uncertainty. After a literature review on risk factors and recommendations for responding to IONM changes, 3 surveys were administered to 8 surgeons with experience in oncological and degenerative spine surgery from 5 hospitals in Italy. In addition, anesthesiologists, intraoperative neuro-monitoring teams, operating room nurses participated. The members participated in the optimization and final drafting of the checklist. The authors reassessed and modified the checklist during 3 meetings over 9 months, including a clinical validation period using a modified Delphi process. A checklist containing 28 items to be considered in responding to the changes of the IONM was created. The checklist was submitted for inclusion in the new recommendations of the Italian Society of Clinical Neurophysiology (SINC) for intraoperative neurophysiological monitoring. The final checklist represents the consensus of a group of experienced spine surgeons. The checklist includes the most important and high-performance items to consider when responding to IONM changes in patients with an unstable spine. The implementation of this checklist has the potential to improve surgical outcomes and patient safety in the field of spinal surgery


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 10 | Pages 1347 - 1353
1 Oct 2009
Grob D Bartanusz V Jeszenszky D Kleinstück FS Lattig F O’Riordan D Mannion AF

In a prospective observational study we compared the two-year outcome of lumbar fusion by a simple technique using translaminar screws (n = 57) with a more extensive method using transforaminal lumbar interbody fusion and pedicular screw fixation (n = 63) in consecutive patients with degenerative disease of the lumbar spine. Outcome was assessed using the validated multidimensional Core Outcome Measures Index. Blood loss and operating time were significantly lower in the translaminar screw group (p < 0.01). The complication rates were similar in each group (2% to 4%). In all, 91% of the patients returned their questionnaire at two-years. The groups did not differ in Core Outcome Measures Index score reduction, 3.6 (sd 2.5) (translaminar screws) vs 4.0 (sd 2.8) (transforaminal lumbar interbody fusion) (p = 0.39); ‘good’ global outcomes, 78% (translaminar screws) vs 78% (transforaminal lumbar interbody fusion) (p = 0.99) or satisfaction with treatment, 82% (translaminar screws) vs 86% (transforaminal lumbar interbody fusion) (p = 0.52).

The two fusion techniques differed markedly in their extent and the cost of the implants, but were associated with almost identical patient-orientated outcomes.

Extensive three-point stabilisation is not always required to achieve satisfactory patient-orientated results at two years.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_8 | Pages 100 - 100
11 Apr 2023
Salamanna F Brodano G Griffoni C Gasbarrini A Fini M Leggi L
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Due to the presence of megakaryocytes, platelets and clotting factors, bone marrow aspirate (BMA) tends to coagulate. For the first time, starting from our previous studies on mesenchymal vertebral stem cells, it has been hypothesized that coagulated BMA represents a safe and effective autologous biological scaffold for bone regeneration in spinal surgery. The present research involved advanced preclinical in vitro models and the execution of a pilot clinical study. Evaluation of cell morphology, growth kinetics, immunophenotyping, clonogenicity, trilineage-differentiation, growth-factors and HOX and TALE gene expression were analyzed on clotted- and un-clotted human V-BMA. In parallel, a pilot clinical study on ten patients with degenerative spine diseases submitted to instrumented posterior arthrodesis, is ongoing to assess the ability of clotted-V-BMA to improve spinal fusion at 6- and 12-months follow-up. Results demonstrated that clotted-V-BMA have significantly higher growth-factor expression and mesenchymal stem cell (MSCs) viability, homogeneity, clonogenicity, and ability to differentiate towards the osteogenic phenotype than un-clotted-V-BMA. Clotted-V-BMA also highlighted significant reduced expression of PBX1 and of MEIS3 genes negatively involved in osteoblast maturation and differentiation. From December 2020, eight patients have already been enrolled with first promising results that will be finally evaluated in the next two months. The application of V-BMA-clot as carrier of progenitors and cytokines and as natural scaffold with a structural texture represents a point-of-care orthobiologic product to improve spinal fusion. Clinical application seems to be efficacy, and we will confirm and strengthen these data with the final results of the pilot clinical study


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_15 | Pages 16 - 16
7 Nov 2023
Khumalo M
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Low back pain is the single most common cause for disability in individuals aged 45 years or younger, it carries tremendous weight in socioeconomic considerations. Degenerative aging of the structural components of the spine can be associated with genetic aspects, lifetime of tissue exposure to mechanical stress & loads and environmental factors. Mechanical consequences of the disc degenerative include loss of disc height, segment instability and increase the load on facets joints. All these can lead to degenerative changes and osteophytes that can narrow the spinal canal. Surgery is indicated in patients with spinal stenosis who have intractable pain, altered quality of life, substantially diminished functional capacity, failed non-surgical treatment and are not candidates for non-surgical treatment. The aim was to determine the reasons for refusal of surgery in patients with established degenerative lumber spine pathology eligible for surgery. All patients meeting the study criteria, patients older than 18 years, patients with both clinical and radiological established symptomatic degenerative lumbar spine pathology and patients eligible for surgery but refusing it were recruited. Questionnaire used to investigate reasons why they are refusing surgery. Results 59 were recruited, fifty-one (86.4 %) females and eight (13.6 %) males. Twenty (33.8 %) were between the age of 51 and 60 years, followed by nineteen (32.2 %) between 61 and 70 years, and fourteen (23.7 %) between 71 and 80 years. 43 (72 %) patients had lumber spondylosis complicated by lumber spine stenosis, followed by nine (15.2 %) with lumbar spine spondylolisthesis and four (6.7 %) had adjacent level disease. 28 (47.4 %) were scared of surgery, fifteen (25.4 %) claimed that they are too old for surgery and nine (15.2 %) were not ready. Findings from this study outlined that patients lack information about the spinal surgery. Patients education about spine surgery is needed


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_11 | Pages 47 - 47
7 Jun 2023
Malik-Tabassum K Ahmed M Jones HW Gill K Board T Gambhir A
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Musculoskeletal disorders have been recognised as common occupational risks for all orthopaedic surgeons. The nature of tasks performed by hip surgeons often requires both forceful and repetitive manoeuvres, potentially putting them at higher risk of musculoskeletal injuries compared to other orthopaedic sub-specialities. This study aimed to investigate the prevalence of musculoskeletal conditions among hip surgeons and evaluate the association between their workplace and lifestyle factors and musculoskeletal health. An online questionnaire consisting of 22 questions was distributed to UK-based consultant hip surgeons via email and social media platforms. This survey was completed by 105 hip surgeons. The mean age of the respondents was 49 years (range 35–69), with an average of 12 years (range 1–33) in service. 94% were full-time and 6% worked part-time. 49% worked at a district general hospital, 49% at a tertiary centre and 4% at a private institution. 80% were on the on-call rota and 69% had additional trauma commitments. 91% reported having one or more, 50% with three or more and 13% with five or more musculoskeletal conditions. 64% attributed their musculoskeletal condition to their profession. The most common musculoskeletal conditions were base of thumb arthritis (22%), subacromial impingement (20%), degenerative lumbar spine (18%) and medial or lateral epicondylitis (18%). 60% stated that they experienced lower back pain. Statistical analysis showed that being on the on-call rota was significantly (P<0.001) associated with a higher musculoskeletal burden. Regular resistance and/or endurance training and BMI<30 were statistically significant protective factors (P<0.001). Over the last few decades, most of the hip-related literature has focused on improving outcomes in patients, yet very little is known about the impact of hip surgery on the musculoskeletal health of hip surgeons. This study highlights a high prevalence of musculoskeletal conditions among UK-based hip surgeons. Hip surgeons have a pivotal role to play in the ongoing recovery of elective orthopaedics services. There is a pressing need for the identification of preventative measures and improvement in the surgical environment of our hip surgeons