Introduction. In vitro studies have shown that low clearance metal-on-metal hip joints have the potential of reducing wear during the running-in phase [1]. However, cementless acetabular cup relies on press fitting into the acetabulum, which can generate non-uniform compressive stresses and non-uniform in vivo cup deformation [2, 3]. This could then lead to equatorial contact, resulting in higher wear and friction for a MoM bearing with low clearance. To benefit from low wear generated by low clearance and at the same time to avoid the potential of head seizure and high frictional torque caused by cup deformation, a deflection compensation acetabular cup (DefCom) has been developed based on the Birmingham Hip Resurfacing (BHR) device. The articulating sphere of the DefCom cup provides a low clearance bearing area, whilst the non-articulating sphere maintains the standard BHR clearance. The aim of this study was to evaluate the wear performance of the novel DefCom hip joint using a hip wear simulator. Materials and Methods. Five pairs of 50 mm DefCom devices were tested in a ProSim hip wear Simulator for 5 million cycles (MC) at a frequency of 1 Hz. The lubricant was new born calf serum with 0.2% sodium azide diluted with de-ionised water to achieve protein concentration of 20 mg/ml. The flexion/extension was 30° and 15° and the internal/external rotation was 10°. The force was Paul-type stance phase loading with a maximum load of 3 kN and a standard ISO swing phase load of 0.3 kN. Five standard 50 mm BHR devices were tested under the same testing conditions for comparison. Statistical analyses were performed at a 95% confidence level (CL) using the statistics function in Excel (Microsoft(r) Excel 2003). Results. Fig. 1 shows the cumulative volume loss against number of wear cycles for the DefCom and the BHR devices. Similar to the BHR device, the DefCom joints experienced relatively higher amount of material loss during the running-in phase from 0 to 1.0 Mc. However, the running-in wear rate for the DefCom device (0.23 ± 0.06 mm. 3. /MC) was much lower than that for the BHR device (0.72 ± 0.15 mm. 3. /MC). Steady state wear was achieved for all the joints from 1.0 to 5.0 MC. The steady state wear rate was 0.11 ± 0.03 mm. 3. /MC for DefCom and 0.18 ± 0.01 mm. 3. /MC for the BHR joints. Discussion. This study has shown that the DefCom acetabular cup has the potential to reduce the initial running-in wear by reducing the clearance at the contact area between the head and cup. The device also has the potential to avoid deformation induced head seizure and high frictional torque by maintaining a larger clearance at the periphery of the cup

Background

Surgical reconstruction of the anterior cruciate ligament is a common practice to treat the disability or chronic instability of the knee. Several factors associated with success or failure of the ACL reconstruction, including surgical technique and graft material and graft tension. We aimed to show how we can optimize the graft properties and achieve better post surgical outcomes during ACL reconstruction using 3-dimensional computational finite element simulation.

Introduction. During its conception, Ilizarov advocated a fine wire tension of between 900N and 1200N for circular frame construction. Wire tension can be achieved via a tensioning device or ‘Russian tensioning’ (a fixed wire lengthening around a bolt). There is limited information on the latter technique. This study aimed to explore the tensions achieved via Russian tensioning and report the impact of a second wire on construct tension. Materials and Methods. A single 160mm stainless-steel ring was constructed, then 1.8mm stainless steel wires secured using a Russian fixation bolt and Russian tensioned with a 2nd bolt. The angle subtended by tensioning using the 2nd bolt was measured using a goniometer. Angles of 45°, 70° and 90° were repeated in triplicates, with wire tension measured using a calibrated tensiometer. A 2nd orthogonal wire was placed on the opposite side and tensioned to the same angle. Tensions of both wires were remeasured and recorded. Statistical comparison using unpaired t-tests was used to compare mean tensions. A value of p<0.05 was considered significant. Results. Russian wire tensioning at all angles was insufficient to achieve the target range of 900–1200N (range 99–110N). The addition of a second orthogonal wire changed frame dynamics such that a 90° angle resulted in both wires achieving adequate tension (mean 1143N, SD 307N). Increases were significant across all tensioning angles (p–<0.002) however only biomechanically relevant for 90°. Conclusions. Russian tensioning is insufficient with a single wire, however the addition of an orthogonal wire increases tension in both wires, which reaches the target range at 90° deflection. This phenomenon is explained by force transmission initially into ring deflection, which is then balanced out by the second wire. Further study of this phenomenon using wire tensioners is warranted, and also the impact of non-orthogonal wire constructs

Introduction. A clinical case of catastrophic ring failure in a 13 year old autistic overweight patient during treatment for tibial lengthening and deformity using a Taylor Spatial Frame is reported. Ring failure was noted during the later stages of bone healing and the frame was removed. The clinical outcome was not affected by the catastrophic ring failure. The photograph of the deformed ring is presented below:. Materials and Methods. The patient's notes and X-rays were reviewed and a macroscopic examination of the deformed ring was performed. Mechanical tests of different Taylor Spatial frame constructs were performed in an attempt to simulate the deformity that was clinically observed. Different constructs of TSF of different ring sizes were fixed to polyurethane cylinders simulating bone, were mechanically tested to failure and load/deflection curves were produced. Results. Macroscopically the ring looked otherwise normal. Gradual mechanical compression tests of Taylor Spatial frame constructs showed that ring deformation increased by increasing the ring diameter and by using jointed rather than full joints without a ring. The ring deformation observed clinically was reproduced at the lab by applying high loads on frame constructs composed of large diameter jointed rings not rigidly fixed to bone. Conclusions. Taylor Spatial frame ring failure during treatment is a serious complication that has not been described in the literature. Possible causes are discussed. Clinicians are advised to use the smaller possible diameter rings. Where large diameter rings are required, these rings should preferably be not jointed. Half rings when used should be carefully and securely joined together by the operating surgeon in order to make a complete ring. For any figures or tables, please contact the authors directly

Despite being demonstrably better than conventional surgical techniques with regards to implant alignment and outlier reduction, computer navigation systems have not faced widespread adoption in surgical operating rooms. We believe that one of the reasons for the low uptake stems from the bulky design of the optical tracker assemblies. These trackers must be rigidly fixed to a patient's bone and they occupy a significant portion of the surgical workspace, which makes them difficult to use. In this study we introduce the design for a new optical tracker system, and subsequently we evaluate the tracker's performance. The novel tracker consists of a set of low-profile flexible pins that can be placed into a rigid body and individually deflect without greatly affecting the pose estimation. By relying on a pin's stiff axial direction while neglecting lateral deviations, we can gain sufficient constraint over the underlying body. We used an unscented Kalman filter based algorithm as a recursive body pose estimator that can account for relative marker displacements. We assessed our tracker's performance through a series of simulations and experiments inspired by a total knee arthroplasty. We found that the flexible tracker performs comparably to conventional trackers with regards to accuracy and precision, with tracking errors under 0.3mm for typical operating conditions. The tracking error remained below 0.5mm during pin deflections of up to 40mm. Our algorithm ran at computation speeds greater than real-time at 30Hz which means that it would be suitable for use in real-time applications. We conclude that this flexible pin concept provides sufficient accuracy to be used as a replacement for rigid trackers in applications where its lower profile, its reduced invasiveness and its robustness to deflection are desirable characteristics

Total shoulder arthroplasty (TSA) is an effective treatment for end-stage glenohumeral arthritis. The use of high modulus uncemented stems causes stress shielding and induces bone resorption of up to 63% of patients following TSA. Shorter length stems with smaller overall dimensions have been studied to reduce stress shielding, however the effect of humeral short stem varus-valgus positioning on bone stress is not known. The purpose of this study was to quantify the effect of humeral short stem varus-valgus angulation on bone stresses after TSA. Three dimensional models of eight male cadaveric humeri (mean±SD age:68±6 years) were created from computed tomography data using MIMICS (Materialise, Belgium). Separate cortical and trabecular bone sections were created, and the resulting bone models were virtually reconstructed three times by an orthopaedic surgeon using an optimally sized short stem humeral implant (Exactech Preserve) that was placed directly in the center of the humeral canal (STD), as well as rotated varus (VAR) or valgus (VAL) until it was contacting the cortex. Bone was meshed using a custom technique which produced identical bone meshes permitting the direct element-to-element comparison of bone stress. Cortical bone was assigned an elastic modulus of 20 GPa and a Poisson's ratio of 0.3. Trabecular bone was assigned varying stiffness based on CT attenuation. A joint reaction force was then applied to the intact and reconstructed humeri representing 45˚ and 75˚ of abduction. Changes in bone stress, as well as the expected bone response based on change in strain energy density was then compared between the intact and reconstructed states for all implant positions. Both varus and valgus positioning of the humeral stem altered both the cortical and trabecular bone stresses from the intact states. Valgus positioning had the greatest negative effect in the lateral quadrant for both cortical and trabecular bone, producing greater stress shielding than both the standard and varus positioned implant. Overall, the varus and standard positions produced values that most closely mimicked the intact state. Surprisingly, valgus positioning produced large amounts of stress shielding in the lateral cortex at both 45˚ and 75˚ of abduction but resulted in a slight decrease in stress shielding in the medial quadrant directly beneath the humeral resection plane. This might have been a result of direct contact between the distal end of the implant and the medial cortex under loading which permitted load transfer, and therefore load-reduction of the lateral cortex during abduction. Conversely, when the implant was placed in the varus angulation, noticeable departures in stress shielding and changes in bones stress were not observed when compared to the optimal STD position. Interestingly, for the varus positioned implant, the deflection of the humerus under load eliminated the distal stem-cortex contact, hence preventing distal load transfer thus precluding the transfer of load

Trabecular bone is a multiscale hierarchical composite material that is known to display time-dependant properties. However, most biomechanical models treat this material as time independent. Time-dependant properties, such as creep and relaxation, are thought to play an important role in many clinically relevant orthopaedic issues: implant loosening, vertebral collapse, and non-traumatic fractures. In this study compressive multiple-load-creep-unload-recovery (MLCUR) tests were applied to human trabecular bone specimens. 15 female femoral heads were harvested, with full ethical approval and patient consent, at the time of total hip replacement. Central cores were extracted and cut parallel under constant irrigation. Specimens were embedded in end caps using surgical cement, an epoxy tube was secured around the end caps and filled with phosphate buffered saline (PBS) to ensure the specimens remained hydrated throughout. Embedded samples were scanned by microCT (SkyScan 1172, Bruker) at a resolution of 17µm to determine microarchitecture. Bone volume fraction (BVF) was used to represent microarchitecture. Specimens had an effective length of 16.37mm (±1.90SD) with diameter of 8.08mm (±0.05SD), and BVF of 19.22% (±5.61SD). The compressive MLCUR tests were conducted at 5 strain levels, 2000µε, 4000µε, 6000µε, 8000µε and 10000µε. At each strain level, the load required to maintain each strain was held for 200s (creep) then unloaded to 1N for 600s (recovery). The instantaneous, creep, unloading and recovered strains can be easily obtained from the strain-time curves. Stress-strain plots revealed the Young's modulus. Data was modelled using line of best fit with appropriate curve fitting. R2 values were used to indicate association. Mechanical testing demonstrated the expected time independent relationship between BVF and stiffness: higher stiffness was found for specimen with higher BVF and this was consistent for all strain levels. Creep strain was found to depend on instantaneous strain and BVF. At low levels of instantaneous strain, there was a greater amount of creep strain in low BVF samples (R2 = 0.524). This relationship was no longer apparent at higher strain levels (R2 = 0.058). Residual strain also depended on the applied instantaneous strain and BVF: at low levels of strain, residual strain was similar with all BVF (R2 = 0.108) and at high levels of strain, residual strain was greater in low BVF samples (R2 = 0.319). The amount of instantaneous strain applied to each sample is constant, variations in stiffness result in different applied loads. In low BVF bone, the stiffness is also low, therefore the stress required to reach designed strain is also lower: yet, there is more creep and less recovery. We have demonstrated that even at loads below recognised yield levels, time-dependence affects the mechanical response and residual strain is present. In cases of low BVF, deflection due to creep, and increased irrecoverable strain could have clinically relevant consequences, such as implant loosening and vertebral collapse. The role of time-dependant properties of bone is seldom considered. This data could be developed into a constitutive model allowing these time-dependant behaviours to be incorporated in finite element modelling, leading to better predictions of implant loosening, especially for lower quality bone

INTRODUCTION. The magnitude of principal strain is indicative of the risks of femoral fracture,. 1,2. while changes in femoral strain energy density (SED) after total hip arthroplasty (THA) have been associated with bone remodeling stimulus. 3. Although previous modeling studies have evaluated femoral strains in the intact and implanted femur under walking loads through successfully predicting physiological hip contact force and femoral muscle forces,. 1,2,3. strains during ‘high load’ activities of daily living have not typically been evaluated. Hence, the objective of this study was to compare femoral strain between the intact and the THA implanted femur under peak loads during simulated walking, stair descent, and stumbling. METHODS. CTs of three cadaveric specimens were used to develop finite element (FE) models of intact and implanted femurs. Implanted models included a commercially-available femoral stem (DePuy Synthes, Warsaw, IN, USA). Young's moduli of the composite bony materials were interpolated from Hounsfield units using a CT phantom and established relationships. 4. Peak hip contact force and femoral muscle forces during walking and stair descent were calculated using a lower extremity musculoskeletal model. 5. and applied to the femur FE models (Fig. 1). While maintaining the peak hip contact forces, muscle forces were further adjusted using an iterative optimization approach in FE models to reduce the femur deflection to the reported physiological range (< 5 mm). 2. Femoral muscle forces during stumbling were estimated utilizing the same optimization approach with literature-reported hip contact forces as input. 6. Maximum and minimum principal strains were calculated for each loading scenario. Changes in SED between intact and THA models were calculated in bony elements around the stem. RESULTS. As expected, high loads during stumbling resulted in the highest peak principal strains along femoral diaphysis (THA: 3179±523 and −4559±629 με; intact: 4232±818 and −5853±204 με) compared to stair descent and typically evaluated gait loads (THA: 1741±363 and −1893±76 με; intact: 2256±887 and −2509±493 με; Fig. 2). Principal strains in THA models peaked close to the tip of the femoral stem across three activities, compared with proximally located peak principal strains in the intact models (Fig. 2). Bony elements located medially and laterally to the femoral stem showed decreased SED after THA, while increased SED was observed in elements distal to the femoral stem (Fig. 3). DISCUSSION. Using appropriately distributed muscle forces, our model predicted similar peak principal strains and SED differences compared with reported values during walking (peak principal strains: ±1500 to ±2000 με. 1,2. ; SED differences: ± 0.02 MPa. 3. ). In addition to the close to failure level principal strains, stumbling showed the most noticeable changes in SED compared with the other two activities. Results suggest iterative bone remodeling simulations should include a composite of activities-of-daily-living loading conditions as well as appropriately distributed muscle forces. For any figures or tables, please contact authors directly

INTRODUCTION. Reverse shoulder arthroplasty (RSA) provides an effective alternative to anatomic shoulder replacements for individuals with cuff tear arthropathy, but certain osteoarthritic glenoid deformities make it challenging to achieve sufficient long term fixation. To compensate for bone loss, increase available bone stock, and lateralize the glenohumeral joint center of rotation, bony increased offset RSA (BIO-RSA) uses a cancellous autograft for baseplate augmentation that is harvested prior to humeral head resection. The motivations for this computational study are twofold: finite element (FE) studies of BIO-RSA are absent from the literature, and guidance in the literature on screw orientations that achieve optimal fixation varies. This study computationally evaluates how screw configuration affects BIO-RSA graft micromotion relative to the implant baseplate and glenoid. METHODS. A senior shoulder specialist (GSA) selected a scapula with a Walch Type B2 deformity from patient CT scans. DICOM images were converted to a 3D model, which underwent simulated BIO-RSA with three screw configurations: 2 divergent superior & inferior locking screws with 2 convergent anterior & posterior compression screws (SILS); 2 convergent anterior & posterior locking screws and 2 superior & inferior compression screws parallel to the baseplate central peg (APLS); and 2 divergent superior & inferior locking screws and 2 divergent anterior & posterior compression screws (AD). The scapula was assigned heterogeneous bone material properties based on the DICOM images’ Hounsfield unit (HU) values, and other components were assigned homogenous properties. Models were then imported into an FE program for analysis. Anterior-posterior and superior-inferior point loads and a lateral-medial distributed load simulated physiologic loading. Micromotion data between the RSA baseplate and bone graft as well as between the bone graft and glenoid were sub-divided into four quadrants. RESULTS. In all but 1 quadrant, APLS performed the worst with the graft having an average micromotion of 347.1µm & 355.9 µm relative to the glenoid and baseplate, respectively. The SILS configuration ranked second, having 211.2 µm & 274.4 µm relative to the glenoid and baseplate. AD performed best, allowing 247.4 µm & 225.4 µm of graft micromotion relative to the glenoid and baseplate. DISCUSSION. Both APLS and SILS techniques are described in the literature for BIO-RSA fixation; however, the data indicate that AD is superior in its ability to reduce graft micromotion, and thus some revision to common practices may be necessary. While these micromotion data are larger than data in the extant RSA literature, there are several factors that account for this. First, to properly model the difference between locking and compression screws, we simulated friction between the compression screw heads and baseplate rather than a tied constraint as done in other studies, resulting in larger micromotion. Second, the trabecular bone graft is at greater risk of deforming than metallic spacers used when studying micromotion with glenosphere lateralization, increasing graft deflection magnitude. Future work will investigate the effects of various BIO-RSA variables. For any figures or tables, please contact authors directly

Valgus knee unloader braces are often prescribed as treatment for knee osteoarthritis (OA). These braces are designed to redistribute the loading in the knee, thereby reducing medial contact forces. Patient response to bracing is variable; some patients experience improvements in joint loading, pain, and function, others see little to no effect. We hypothesised that patients who experienced beneficial response to the brace, measured by reductions in medial contact force, could be predicted based on static and dynamic measures. Participants completed a WOMAC questionnaire and walked overground with and without an OA Assist knee brace in a motion capture lab. Eighteen patients with medial compartment OA (8 female, 53.8±7.0 years, BMI 30.3±4.1, median Kellgren-Lawrence grade 4 (range 1–4)) were evaluated. The abduction moment applied by the brace was estimated by multiplying brace deflection by the pre-determined brace stiffness. A generic musculoskeletal model was scaled for each participant based on standing full length radiographs and anatomical markers. Inverse kinematics, inverse dynamics, residual reduction, and muscle analysis were completed in OpenSim 3.2. A static optimisation was then performed to estimate muscle forces and then tibiofemoral contact forces were calculated. Brace effectiveness was defined by the difference in the first peak of the medial contact force between braced and unbraced conditions. Principal component analysis was performed on the hip, knee, and ankle angles and moments from the unbraced walking condition to extract the principal component (PC) scores for these variables. A linear regression procedure was used to determine which variables related to brace effectiveness. Potential regressors included: hip-knee-ankle angle and medial joint space measured radiographically; KL grade; mass; WOMAC scores; unbraced walking speed; and the first two principal component scores for each of the unbraced hip, knee, and ankle joint angles and moments. KL grade, walking speed, and hip adduction moment PC1, which represented the magnitude of the first peak were all found to be correlated with change in medial contact force. The brace was more successful in reducing medial contact force in subjects with higher KL grades, faster self-selected walking speeds, and larger peak external hip adduction moments. The R2 value for the overall regression model was 0.78. The best predictor of brace effectiveness was the hip adduction moment, indicating the need to consider dynamic measures. Participants who had hip adduction moments and walking speeds similar to those of their healthy counterparts saw a greater reduction in medial contact force. Thus, those who responded to bracing had more severe OA as measured by the KL grade but had not experienced changes in their hip adduction moment due to OA. The results of this study suggest that there is potential for an objective criterion for valgus knee brace use to be established

Introduction. The use modular total hip arthroplasty is associated with potentially serious local and systemic complications. Each modular interface introduces a source for wear particle generation. Research suggests the etiology of wear particle generation and subsequent corrosion begins with mechanical fretting and disruption of the protective oxide layer leading to release of metal ions at the taper interface. The purpose of this study was to conduct three dimensional (3D) surface scans of the mating surfaces of the neck-stem taper to identify features that may contribute to the fretting and surface corrosion. Methods. Eighteen modular hip implant components (9 stems and 9 necks) received 3D surface scans to examine the neck-stem taper junction. The study analyzed the neck-stem taper in an as assembled condition so relative surface positions and surface features could be studied. The 9 stems and 9 necks were scanned using an optical scanner. The implant image volume was resolved to a point spacing of 0.5 mm. Measurements were made to determine the normal distance between the surfaces of the neck taper as seated in the stem slot. These measurements were used to produce a color map of the contact proximity between the neck and stem surfaces (Figure 1). Circumferential surface points from the neck and stem at corresponding taper axis heights were used to create surface contour plots to identify surface shape variation and contact. The angle measurements and neck seated depth were analyzed by regression. Results. The typical features observed in these contact maps were: 1) a distinct vertically running line of contact at one end of the transition from the flat surface section to the radius surface section, and present on opposite surfaces in the same location; 2) distinct vertically running line of contact in the radius surface section just past the centerline on the side further away from the transition contact, and also present on the opposite radius section in the same location; 3) a concavity or area of no contact along the flat surface exists between the neck and stem components; and 4) one of the neck flat surfaces was closer to its mating surface on the stem. The plot colors show contact proximity ranging from 0 – 0.025 mm, 0.025 – 0.050 mm, and 0.050 – 0.075 mm. The average neck seated depth in the stem was 14.181 mm, ranging from 13.796 mm to 14.422 mm. Regression analysis showed that the seated depth of the neck was dependent on the taper angles in the flat section of the neck (R. 2. = 0.5000, p = 0.0332). Conclusions. Three dimensional scans and analysis suggest that the shape of the neck and stem tapers deviate from ideal design dimensions, which results in a contact pattern and component fit with gaps between the mating surfaces and rotated alignment. The probable cause of the dimensional deviation is due to machine tool deflection during manufacture. The combination of the contact and fit is expected to contribute to relative motions between the neck and stem, exacerbating the MACC

The advent of Elastic Stable Intramedullary Nailing has revolutionised the conservative treatment of long human bone fractures in children (Metaizeau, 1988; Metaizeau et al., 2004). Unfortunately, failures still occur due to excessive bending and fatigue (Linhart et al., 1999; Lascombes et al., 2006), bone refracture or nail failure (Bråten et al., 1993; Weinberg et al., 2003). Ideally, during surgery, nail insertion into the diaphyseal medullary canal should not interrupt or injure cartilage growth; nails should provide an improved rigidity and fracture stabilisation. This study aims at comparing deflections and stiffnesses of nail-bone assemblies: standard cylindrically-shaped nails (MI) vs. new cylindrical nails (MII) with a flattened face across the entire length allowing more inertia and a curved tip allowing better penetration into the cancellous bone of the metaphysis (Figure 1). MII exhibits a section with two parameters: a diameter C providing nail stiffness and a height C' providing practical dimension when both nails are crossed at the isthmus of the diaphysis: C/C' is set to 1.25 for all MII nails. A CT scan of a patient aged 22 years was used to segment a 3D model of a 471mm-long right femur model. The medullary canal diameters at the isthmus are 10.8mm and 11.4mm in the ML and AP direction, respectively. Titanium-made CAD models of MI (Ø=4mm) and MII (flat face: Ø=5mm) were pre-curved to maintain their flat face and carefully placed and positioned according to surgeon's instructions. Both nails were inserted via lateral holes in the distal femur with their extremities either bumping against the cortex or lying in the trabecular bone. Transverse and comminuted fractures were simulated (Figure 1). For each assembly, a Finite Element (FE) tetrahedral mesh was generated (∼100181 nodes and 424398 elements). Grey-scale levels were used to assign heterogeneous material properties to the bone (E=6850 ρ. 1.49. (Morgan et al., 2003)). Two modes of loading were considered: 4-point bending (varus and recurvatum: F. max. =6000N) and internal torsion (M. max. =70kNmm). This led to the simulation of 15 FE models, including a reference intact femur. Results show that in valgus, for the transverse (comminuted) fracture, the mean displacement of the assembly decreased by around 50%: from 15.24mm (27.49mm) to 8.15mm (13.85mm) for MI and MII, respectively, compared to 3.59mm for the intact bone. The assembly stiffness increased by 87% and 99% for transverse and comminuted fracture, respectively (Table 1). Similar trends were found in recurvatum with higher increases in assembly stiffness of 170% and 143% for transverse and comminuted fracture, respectively (Table 1). In torsion, for the transverse (comminuted) fracture, the measured angle of rotation decreased from: 0.43rad (0.66rad) to 0.22rad (0.43rad) for MI and MII, respectively, compared to 0.09rad for the intact bone. This corresponded to an increase of 95% and 55% in assembly stiffness for transverse and comminuted fracture, respectively. In conclusion, using the 5mm-diameter new nails (MII) for the same intramedullar space, during either bending or torsion, assemblies were always stiffer than when using standard cylindrical nails

INTRODUCTION. Deformation of modular acetabular press-fit shells is a topic of much interest for surgeons and manufacturer. Such modular components utilise a titanium shell with a liner manufactured from metal, polyethylene or ceramic. Initial fixation is achieved through a press-fit between shell and acetabulum with the shell mechanically deforming upon insertion. Shell deformation may disrupt the assembly process of inserting the bearing liner into the acetabular shell for modular systems. This may adversely affect the integrity and durability of the components and the tribology of the bearing. OBJECTIVE. Most clinically relevant data to quantify and understand such shell deformation can be achieved by cadaver measurements. ATOS Triple Scan III was identified as a measurement system with the potential to perform those measurements. The study aim was to validate an ATOS Triple Scan III optical measurement system against a co-ordinate measuring machine (CMM) using in-vitro testing and to check capability/ repeatability under cadaver lab conditions. METHODS. Two sizes of custom-made acetabular shells were deformed using a uniaxial/ two-point loading frame and measured repeatedly at different loads. Roundness measurements were performed using both the ATOS Triple Scan III optical system and a co-ordinate measuring machine and then compared. The repeatability was also tested by measuring shells pre and post insertion in a cadaver lab multiple times. RESULTS. The in-vitro comparison with CMM demonstrated a maximum difference of 5 µm at the rim and 9 µm at the measurement point closest to the pole of the shell. Deviation between the two systems increased towards the pole for the in-vitro measurements. However as press fit shells are designed to be loaded at the rim, this is likely where the maximum deflection will occur as a result of the highest force. Therefore, the increased difference between the systems towards the pole is of less importance compared with accuracy at the rim. Maximum repeatability was below 1 µm for the CMM and 3 µm for the ATOS Triple Scan III optical system. Repeatability of the ATOS Triple Scan III optical system was comparable between pre insertion (below 2 µm) and post insertion (below 3 µm) measurements in the cadaver lab. In addition these values were comparable to the repeatability measured during the in-vitro validation study (below 3 µm). This proves high repeatability not only for in-vitro conditions, but also for the cadaver lab as well. CONCLUSIONS. This study supports the view that the ATOS Triple Scan III optical system fulfils the necessary requirements to accurately measure shell deformation in cadavers. As a result, the authors propose further studies using cadavers to identify the impact of other factors upon shell deformation. Other factors to be measured include bone strength, shell diameter, under reaming and wall thickness

Introduction. Total hip replacement is an established surgical procedure done to alleviate hip pain due to joint diseases. However, this procedure is avoided in yonger patients with higher functional demands due to the potential for early failure. An ideal prosthesis will have have a high endurance against impact loading, with minimal micromotion at the bone cement interface, and a reduced risk of fatigue failure, with a favourable stress distribution pattern in the femur. We study the effect of varying the material properties and design element in a standard cemented total hip using Finite Element Analysis. Methods. A patient-specific 3D model of femur will be constructed from CT scan data, while a Summit® Cemented Hip System (DePuy Orthopedic) will be used to as a control for comparative evaluation. We vary the material stiffness of different parts of the prosthesis(see Fig.1) to formulate a design concept for a new total hip prosthesis design; and use Finite Element Method to predict the micromotion of the hip prosthesis at the bone cement interface, as well as the stress distribution in the the femur. Result. Validation of computational protocol was being done by comparing the principal maximum strain of the femoral cortex along the diaphysis, and the amount of deflection, with published literature, similarly, contact modelling validation was also done. Model 1–4 induced lower peak Von Mises stress in the cement, which takes a much lower value than any of the cement mechanical limits postulated. Therefore, the risk of cement failure is greatly reduced in Model 1–4. However, the effect of varying stiffness in different regions is not significant in terms of load transmission to the cement. Micromotion at the bone-cement interface was studied via two approaches: Peak micromotion at the bone cement interface; and the micromotion data at 12 Regions of Interest (ROI)s. Both results showed that model 2 and 3 are capable of reducing micromotion at bone-cement interface, in comparison with the Summit® Cemented Hip System. By comparing the Von Mises Stress distribution in the proximal femur; model 1 is found to result in a significantly reduced stress shielding effect, while model 2–4 are also favourable in comparison to the standard Summit® prosthesis in terms of stress distribution in the femur. Figure 2 shows the effects of the performance of model 1–4, presented as percentage difference from the Summit® prosthesis. Model 1 is unfavourable, despite its favourable stress distribution, because its peak and overall micromotion at the bone-cement interface is greatly increased. Conclusion. Model 2 and 3 have favourable design elements. They both have reduced micromotion at the bone-cement interface; and a favourable stress distribution in the femur. Further refining and testing of model 2 and 3 should done, as these models may provide information which may be useful in improving the performance of the current range of total hip replacement prostheses

Purpose. Glenoid component loosening is a common reason for failed total shoulder arthroplasty. Multiple factors have been suggested as causes for component loosening that may be related to cement technique. The purpose of the study was to compare the load transfer across a polyethylene glenoid bone construct with two different cementing techniques. Method. Eight cadaveric specimens underwent polyethylene glenoid component implantation. Four had cement around the pegs only (CPEG) and four had cement across the entire back (CBACK) of the implant including around the pegs. Step loading was performed with a pneumatic actuator and a non-conforming humeral head construct capable of applying loads at various angles. Strain gauges were placed at the superior and inferior poles of the glenoid and position trackers were applied to the superior and inferior aspects polyethylene component. Micro CT data were obtained before and after the loading protocol. Results. During compressive loading, greater tension was recorded with the CBACK technique than with the CPEG technique. Compression was recorded superiorly when load was applied at 30 degrees while tension was recorded inferiorly. Greater displacement occurred with the CPEG group. Failure as defined on micro CT occurred more consistently with the CBACK technique than with the CPEG technique. Conclusion. Tension measurements and upward deflection of the polyethylene with compressive loading at lower angles was unexpected. Early failure of fully cemented glenoids may be due to the fragility of the cement mantle around the periphery of the implant. Tension at the bone cement interface and early cement fracture are unfavorable and this may be a mechanism of implant loosening

Introduction. High tibial osteotomy (HTO) is a commonly used surgical technique for treating moderate osteoarthritis (OA) of the medial compartment of the knee by shifting the center of force towards the lateral compartment. The amount of alignment correction to be performed is usually calculated prior to surgery and it's based on the patient's lower limb alignment using long-leg radiographs. While the procedure is generally effective at relieving symptoms, an accurate estimation of change in intraarticular contact pressures and contact surface area has not been developed. Using electromyography (EMG), Meyer et al. attempted to predict intraarticular contact pressures during gait patterns in a patient who had received a cruciate retaining force-measuring tibial prosthesis. Lundberg et al. used data from the Third Grand Challenge Competition to improve contact force predictions in total knee replacement. Mina et al. performed high tibial osteotomy on eight human cadaveric knees with osteochondral defects in the medial compartment. They determined that complete unloading of the medial compartment occurred at between 6° and 10° of valgus, and that contact pressure was similarly distributed between the medial and lateral compartments at alignments of 0° to 4° of valgus. In the current study, we hypothesised that it would be possible to predict the change in intra-articular pressures based on extra-articular data acquisition. Methods. Seven cadavers underwent an HTO procedure with sequential 5º valgus realignment of the leg up to 15º of correction. A previously developed stainless-steel device with integrated load cell was used to axially load the leg. Pressure-sensitive sensors were used to measure intra-articular contact pressures. Intraoperative changes in alignment were monitored in real time using computer navigation. An axial loading force was applied to the leg in the caudal-craneal direction and gradually ramped up from 0 to 550 N. Intra-articular contact pressure (kg) and contact area (mm2) data were collected. Generalised linear models were constructed to estimate the change in contact pressure based on extra-articular force and alignment data. Results. The application of an axial load results in axial angle changes and load distribution changes inside the knee joint. Preliminary analysis has shown that it is possible to predict lateral and medial compartment pressures using externally acquired data. For lateral compartment pressure estimation, the following equation had an R of 0.86: Lateral compartment pressure = −1.26*axial_force + 37.08*horizontal_force − 2.40*vertical_force − 271.66*axial_torque − 32.64*horizontal_torque + 18.98*vertical_torque − 24.97*varusvalgus_angle_change + 86.68*anterecurvature_angle_change − 17.33*axial_angle_change − 26.14. For medial compartment pressure estimation, the following equation had an R2 of 0.86: Medial compartment pressure = −2.95*axial_force −22.93*horizontal_force − 9.48*vertical_force − 34.53*axial_torque + 6.18*horizontal_torque − 127.00*vertical_torque − 110.10*varusvalgus_angle_change − 15.10*anterecurvature_angle_change + 55.00*axial_angle_change + 193.91. Discussion. The most important finding of this study was that intra-articular pressure changes in the knee could be accurately estimated given a set of extra-articular parameters. The results from this study could be helpful in developing more accurate lower limb realignment procedures. This work complements and expands on previous research by other groups aimed at predicting intra-articular pressures and identifying optimal alignment for unloading arthritic defects. A possible clinical application of these findings may involve the application of a predetermined axial force to the leg intra-operatively. Given the estimated output from the predictive equation, one could then perform the opening wedge until the desired estimated intra-articular pressure is achieved. With this method, an arthrotomy and placement of intra-articular pressure sensors would not be needed. This work is not without its limitations. This experiment was performed on cadaveric specimens. Therefore, we cannot directly predict what the pressures would be in a de-ambulating patient. However, these sort of experiments do help us understand the complex biomechanics of the knee in response to alterations in multi-planar alignment. Further in vivo research would be warranted to validate these results. Additionally, given our current experimental setup, only axial loading could be performed for testing. Further experiments involving dynamic motion of the lower limb under load would further help us understand the changes in pressure at difference flexion angles. Continued experiments would help us gather additional data to better understand the relationship between these variables and to construct a more accurate predictive model. In summary, we have established a framework for estimating the change in intra-articular contact pressures based on extra-articular, computer-navigated measurements. Quantifying the resulting changes in load distribution, alignment changes, torque generation and deflection will be essential for generating appropriate algorithms able to estimate joint alignment changes based on applied loads

Introduction. One of the important criteria of the success of TKR is achievement of the Flexion ROM. Various factors responsible to achieve flexion are technique, Implant and patient related. Creation of the Posterior condylar offset is one such important factor to achieve satisfactory flexion. Aim. To correlate post op femoral condylar offset to final flexion ROM at 1 yr. post op. Methods. This is a clinico-radiological study of the cases done prospectively between September 2011 and August 2012. Inclusion criteria:. All patients undergoing Bilateral TKRs and have agreed for the follow up at 1 yr. Exclusion criteria:. Patients who had previous bony surgery on lower end femur. Patients with previous fracture of lower end femur. All the patients had PS PFC Sigma (De Puy, Warsaw) components cemented. ROMs were measured at 6 weeks, 3 months, & 1 year post op. The last reading was taken as final flexion ROM as measured by a Physiotherapist with the help of a Goniometer. Results. We had 21 cases of Bilateral TKRs who satisfied our criteria. Pre and post op femoral condylar offset was measured in mm. on lateral x ray. Pre and post op flexion was measured. Results showed that variation in the posterior femoral offset by > 3mm in post op x ray was related to loss of flexion of an average 21 deg. (16 – 24 degrees). Greater the deflection from the normal offset, greater was the loss of flexion. These patients also showed lesser improvement in KSS functional score. Discussion. Flexion is one of the most important yardsticks for the measurement of success of TKR. This factor is more important more so in Asian population. Literature has shown that three important determinants for good flexion are…. Posterior Condylar Offset Restoration. Tibial slope restoration. Femoral Roll back in flexion. An increased offset permits greater flexion before impingement between the tibial insert and the femur. In our study we kept Tibial slope and Femoral Roll back constant by using the same prosthesis. The femoral condylar offset changed as per the size of the AP femoral cutting block. (Anterior referencing guide used). Overresection of the posterior condyles reduced the posterior femoral condylar offset and hence significant loss of post op flexion. The shorter posterior condyle of smaller femoral component can increase the potential for bone impingement proximal to the posterior condyles. In our study the opposite side replaced knee acted as a control. It is generally stated that after a TKR flexion can improve upto 1 year and hence was taken as final possible flexion. Conclusion. Keeping Tibial slope and Femoral roll back constant during the surgery, posterior condylar offset restoration within 3 mm of its original pre op offset was necessary to achieve satisfactory flexion at 1 year. Undersizing the femoral component to achieve more flexion is perhaps suboptimal. Appropriate AP femoral sizing is a must to restore the normal offset

Anti-vehicle mines (AV) and Improvised Explosive Devices (IEDs) remain the most prevalent threat to Coalition troops operating in Iraq and Afghanistan. Detonation of these devices results in rapid deflection of the vehicle floor resulting in severe injuries to calcaneus. Anecdotally referred to as a ‘deck-slap’ injury, there have been no studies evaluating the pattern of injury or the effect of these potentially devastating injuries since World War II. Therefore the aim of this study is to determine the pattern of injury, medical management and functional outcome of UK Service Personnel sustaining calcaneal injuries from under-vehicle explosions. From Jan 2006 – Dec 2008, utilising a prospectively collected trauma registry (Joint Theatre Trauma Registry, JTTR), the records of all UK Service Personnel sustaining a fractured calcaneus from a vehicle explosion were identified for in depth review. For each patient, demographic data, New Injury Severity Score (NISS), and associated injuries were recorded. In addition, the pattern of calcaneal fracture, the method of stabilisation, local complications and need for amputation was noted. Functional recovery was related to the ability of the casualty to return to military duties. Forty calcaneal fractures (30 patients) were identified in this study. Mean follow-up was 33.2 months. The median NISS was 17, with the lower extremity the most severely injured body region in 90% of cases. Nine (30%) had an associated spinal injury. The overall amputation rate was 45% (18/40); 11 limbs (28%) were amputated primarily, with a further 3 amputated on return to the UK. Four (10%) casualties required a delayed amputation for chronic pain (mean 19.5 months). Of the 29 calcaneal fractures salvaged at the field hospital, wound infection developed in 11 (38%). At final follow-up, only 2 (6%) were able to return to full military duty with 23 (76%) only fit for sedentary work or unfit any military duty. Calcaneal injuries following under-vehicle explosions are commonly associated with significant polytrauma, of which the lower limb injury is the most severe. Spinal injuries were frequently associated with this injury pattern and it is recommended that radiological evaluation of the spine be performed on all patients presenting with calcaneal injuries from this injury mechanism. The severity of the hindfoot injury witnessed is reflected by the high infection rate and amputation rate seen in this cohort of patients. Given the high physical demands of a young, active military population, only a small proportion of casualties were able to return to pre-injury duties. We believe that the key to the reduction in the injury burden to the soldier lies in the primary prevention of this injury. Work is currently on going to develop experimental and numerical models of this injury in order to drive future mitigation strategies

Introduction:. One of the important criteria of the success of TKR is achievement of the Flexion ROM. Various factors responsible to achieve flexion are technique, Implant and patient related. Creation of the Posterior condylar offset is one of the important factors to achieve satisfactory flexion. Aim:. To correlate post op femoral condylar offset to final flexion ROM at 1 yr. post op. Methods:. This is a clinico-radiological study of the cases done prospectively between September 2011 and August 2012. Inclusion criteria:. All patients undergoing Bilateral TKRs and have agreed for the follow up at 1 yr. Exclusion criteria: . 1). Patients who had previous bony surgery on lower end femur. 2). Patients with previous fracture of lower end femur. All the patients had PS PFC Sigma (De Puy, Warsaw) components cemented. ROMs were measured at 6 weeks, 3 months, & 1 year post op. The last reading was taken as final flexion ROM as measured by an independent Physiotherapist with the help of a Goniometer. Results:. We had 21 cases of Bilateral TKRs who satisfied our criteria. Pre and post op femoral condylar offset was measured in mm. on lateral x ray. Pre and post op flexion was measured. Results showed that variation in the posterior femoral offset by > 3 mm in post op x ray was related to loss of flexion of an average 21 deg. (16–24 degrees). Greater the deflection from the normal offset, greater was the loss of flexion. These patients also showed lesser improvement in KSS functional sco. Discussion:. Flexion is one of the most important yardsticks for the measurement of success of TKR. This factor is more important more so in Asian population. Literature has shown that three important determinants for good flexion are…. . 1). Posterior Condylar Offset Restoration. 2). Tibial slope restoration. 3). Femoral Roll back in flexion. An increased offset permits greater flexion before impingement between the tibial insert and the femur. In our study we kept Tibial slope and Femoral Roll back constant by using the same prosthesis. The femoral condylar offset changed as per the size of the AP femoral cutting block. (Anterior referencing guide used). Overresection of the posterior condyles reduced the posterior femoral condylar offset and hence significant loss of post op flexion. The shorter posterior condyle of smaller-sized femoral component can increase the potential for bone impingement proximal to the posterior condyles. In our study the opposite side replaced knee acted as a control and hence eliminating patient bius. It is generally stated that after a TKR flexion can improve upto 1 year and hence that was taken as final possible flexion. Conclusion:. Keeping Tibial slope and Femoral roll back constant during the surgery, posterior condylar offset restoration within 3 mm of its original pre op offset was necessary to achieve satisfactory flexion at 1 year. Undersizing the femoral component to achieve more flexion is perhaps suboptimal. Appropriate AP femoral sizing is a must to restore the normal offset

Introduction. The prevalence of reversing of extension coronal deformity during flexion and how that may change the routine algorithm of soft tissue balancing in total knee arthroplasty (TKA) has not been published. We name this phenomenon, the reversing coronal deformity (RCD). We observed 12% (45 patients) of coronal deformities consistently reverse in flexion in the osteoarthritic knees before surgery. We conclude that RCD phenomena need to be addressed in every TKA and collateral ligament release need to be modified or avoided; otherwise postoperative flexion instability may be inevitable. Femoral rotation adjustment with posterior capsule release has to be attempted first in RCD patients. Method. We define RCD as the reversing of a coronal extension deformity of more than 2° while the knee reaches 90°of flexion. That is to say a 2° or more varus knee in extension becomes a 2° or more valgus at 90° of flexion or vice versa. We retrospectively analyzed, in a multicenter study the alignment patterns of 387 (US = 270, UK = 117) consecutive computer navigated TKA subjects (June 2004–May 2008). 364/387 (US = 252, UK = 112) subjects were eligible for analysis (23 subjects had incomplete data: US = 18, UK = 5). The coronal deformity kinematics was observed during the range of motion and the range of medial /lateral deflections were analyzed. Result:. 260/364 subjects had varus knees and 104/364 subjects had valgus knees. 18 subjects (7%) of the varus knees reversed to valgus and 27 subjects (26%) of valgus knees reversed to varus by 90°pre-operatively. Therefore, the total number of arthritic knees that reversed their coronal deformity from extension to 90° flexion was 45 (12.4%). Knee alignment in extension was 0° ± 2° in 99% of patients. 1% (4 subjects) had more than 2°of varus or valgus in extension. Collateral ligament was released in 4/45 RCD patients in which all had flexion instability of more than 10° (medial/lateral at 90°). The other 40 patients had posterior capsule release with or without femoral rotation adjustment to balance the flexion gap. None of them had flexion instability (medial /later gaping was 4° or less). The preoperative mean femoral rotation was 3.05° of external rotation (ER) in varus knees and 1.9° ER in valgus knee. While in RCD varus knees, the mean femoral rotation was 1.5 ° ER and RCD valgus knees 2.5°ER. Discussion and Conclusion. Our observation has shed the light on a new concept in the kinematics of the knee, namely the reversing of the coronal deformity (RCD) during flexion which occurs in 12% of patients undergoing TKA. Basically, a varus knee in extension behaves like a valgus knee in flexion and vice versa. It is crucial to be aware of this phenomenon when attempting to do soft tissue release to balance the gaps in TKA. Otherwise, widening one gap in extension to correct a fixed deformity may result in an unacceptable overcorrection of the same gap in flexion in those knees that manifest the reverse coronal deformity phenomena. Soft tissue balance algorithm was noted to be different in such cases in which early collateral ligament release resulted in flexion instability