Purpose. Long-term clinical and radiographic results and survival rates were compared between closed-wedge high tibial osteotomy (HTOs) and fixed-bearing unicompartmental knee arthroplasty (UKA) in patients with similar demographics. Methods. Sixty HTOs and 50 UKAs completed between 1992 and 1998 were retrospectively reviewed. There were no significant differences in preoperative demographics. The mean follow-up period was 10.7 ±5.7 years for HTO and 12.0 ±7.1 years for UKA (n.s.). The Knee Society knee and function scores, WOMAC, and range of motion (ROM) were investigated. The mechanical axis and femorotibial angle were evaluated. Kaplan–Meier survival analysis was performed (failure: revision to TKA), and the failure modes were investigated. Results. Most of the clinical and radiographic results were not different at the last follow-up, except ROM; ROM was 135.3 ±12.3° in HTO and 126.8 ±13.3° in UKA (p=0.005). The 5-, 10-, 15-, and 20-year survival rates were 100%, 91.0%, 63.4%, and 48.3% for closed-wedge HTO, respectively, and 90.5%, 87.1%, 70.8%, and 66.4% for UKA (n.s.). The survival rate was higher than that for UKA until 12 years postoperatively but was higher in UKAs thereafter, following a remarkable decrease in HTO. The most common failure mode was degenerative osteoarthritic progression of medial compartment in HTO and femoral component loosening in UKA. Conclusions. Long-term survival did not differ significantly between closed-wedge HTO and fixed-bearing UKA in patients with similar preoperative demographics and knee conditions. The difference in postoperative ROM and failure mode should be considered when selecting a procedure

Objective. The purpose of the present study was to compare the clinical and radiographic results after TKA using a patellofemoral design modified prosthesis and its predecessor. The other purpose was to investigate whether the use of the recent prosthesis increase the risk of posterior tibial cortex injury or patellar fracture. Materials and Methods. The clinical and radiographic results of 300 knees which underwent TKA using the Attune®prosthesis (group A) were compared with those in a paired match-control group who underwent TKA using the P.F.C. Sigma® prosthesis (group B). The preoperative demographic data between the 2 groups did not differ significantly. The WOMAC, Feller and Kujala scores, and range of motion (ROM) were compared. The minimal distance between the tibial component stem to posterior tibial cortex, and the remnant patella thickness were compared. Results. The postoperative WOMAC score was better in the group A than in the group B (17.7 vs. 18.8, p=0.004). The postoperative ROM was greater in the group A than in the group B (131.4° vs. 129.0°, p=0.008). The postoperative Feller score was not different, but postoperative Kujala score was better in the group A. The minimal distance between the tibial component stem and posterior tibial cortex was significantly shorter in group A than in the group B (6.3mm vs 7.0mm, p<0.001). The proportion of high risk group for posterior tibial cortical injury, which had the minimal distance less than 4mm, was higher in the group A (20.0% vs 10.7%, p=0.002). The remnant patella was thinner in the group A than in the group B (14.8mm vs 15.7mm, p<0.001). The proportion of high risk group for patella fracture with remnant thickness of <12mm was higher in the group A (7.5% vs 2.1%, p=0.003). Conclusion. When comparing the clinical and radiographic results after TKA using the two prostheses of a design modified prosthesis and its predecessor, TKA using the recent prosthesis provided better satisfactory results. However, the risk of injury in the posterior cortex of the tibial metaphysis or remnant patella should be considered in this design modified prosthesis. Level of Evidence. Level III

INTRODUCTION. In patients presenting with significant ligamentous instability/insufficiency and/or significant varus/valgus deformity of the knee, reproduction of knee alignment and soft tissue stability continues to be a difficult task to achieve. These complex primary total knee arthroplasty (TKA) candidates generally require TKA systems incorporating increasing levels of constraint due to the soft-tissue and/or bone deficiencies. In addition, achievement of “normal” gap symmetry through physiologic kinematics is challenging due to the complexity of the overall correction. Advancements in TKA design have not fully addressed the negative consequences of the increased forces between the degree of component constraint, the femoral box, and the tibial post. The purpose of this early feasibility study was to introduce the design characteristics of a primary TKA system that incorporates progressive constraint kinematics using a low profile trapezoidal femoral box, and to assess the short-term clinical and radiographic results of this patient cohort. METHODS. We retrospectively evaluated 22 consecutive, non-selected, complex primary TKA patients with a minimum of 3-years follow-up and varus deformity of > 20 degrees or valgus deformity of >15 degrees. The Progressive Constraint Kinematics® Knee System (PCK, MAXX Orthopedics, Norristown, PA) was used and provides a variable constraint profile, from high constraint in extension to less constraint in flexion through a novel trapezoidal femoral box. We evaluated patient demographics, pre- and post-operative serial radiography, range of motion (ROM), and total Knee Society Score (KSS – total score). General descriptive statistics and paired t-Test to assess the difference between means at p <0.05 level of significance. RESULTS. The average time to most recent follow-up was 40.5 ±3.5 months (range: 36.0 to 44.0 months). The PCK knee system had 100% survival rate at the most recent follow-up, with no reports of adverse events, subsequent corrective surgery, or revision. The average total KSS improved from 72.7 ±3.2 (range: 68 to 81) pre-operatively to 92.3 ±2.1 (range: 88 to 96) post-operatively (p < 0.001). Full post-operative arc of motion was 0 – 130° and there was no radiographic evidence of composite degradation, aseptic loosening or component malalignment. DISCUSSION/CONCLUSION. The PCK Knee System utilizes a trapezoidal shaped femoral box, where the narrower end is located anteriorly, allowing a valgus/varus tilt of 1–4 degrees and internal/external rotation of 2–7 degrees during flexion, while maintaining necessary soft-tissue constraint during extension. This variable constraint profile allows for fully tensed collaterals in extension, with a slight reduction in collateral tension through flexion. Furthermore, the combination of the condylar anatomy, trapezoidal femoral box and tibial post allows for adequate clearance through full flexion, while facilitating slightly progressive increases in tilt and rotation, thereby maintaining knee kinematics while dampening forces transmitted through the prosthetic composite. From this feasibility study we report promising short-term clinical and radiographic results in the absence of biomechanical failure in complex primary TKA cases. We recommend continuation of the use and further research of the PCK Knee System for complex primary TKA with the ultimate goal of further determining cost effectiveness and intermediate to long-term clinical relevance

Introduction. Long term results of Total Hip Arthroplasty (THA) are affected by wear of articulation. Ceramic on ceramic articulation have been used especially for young patients because of its low wear and bio-inert property. However, because of its hardness, it is concerned that ceramic fracture, chipping, or squeaking might happen with ceramic on ceramic articulation. Objective. The purpose of this study was to investigate over 10-years clinical and radiographic results of ceramic bearing cementless THA. Methods. Evaluation was performed in 60 patients (68 joints) who underwent primary cementless THA from May 2003 to April 2007. Mean age at surgery was 59 years. Mean follow up period was 11.2 years. Forty-nine patients were female. Mean BMI at surgery was 24.0 kg/m. 2. Fifty-one patients had osteoarthrosis, 6 patients had osteonecrosis, 2 patients had rheumatoid arthraitis, and 1 patient had PSS. A 28mm-size femoral head was used in all patients. Clinical evaluation was performed with Japanese Orthopaedic Association Hip Score (JOA score). Radiographic results were evaluated with standard bilateral hip radiograph in supine position. Results. Mean clinical score at surgery was 45 (pain: 13/40, ROM: 12/20, gait: 9/20, ADL: 12/20). Mean clinical score at final follow up was 92 (pain: 39/40, ROM: 17/20, gait: 17/20, ADL: 18/20). Pain score was dramatically improved from 13 to 39 (maximum pain score: 40). One stem was revised because of recurrent dislocation. Two other patients experienced one time dislocation during follow up. One stem showed 5mm of subsidence. ALL cups and stems showed bone ingrowth at final follow up. Cortical hypertrophy was seen in 17 joints. However, there was no patient complained thigh pain. Stress shielding was seen in 55 joints (81%). First, second and third degree of stress shielding were seen in 12, 40, and 3 joints, respectively. Most of the female patients who had surgery at the age over 60 years showed second and third degree of stress shielding. There was no measurable wear. No osteolysis was found around the implants. There were no ceramic fracture, chipping, and squeaking. Conclusion. This study demonstrated excellent clinical and radiographic results of ceramic bearing cementless THA. Excellent long term results will be expected with this system

Introduction. Female gender, old age (men >60y and women > 55y), severe acetabular dysplasia, poor proximal femoral bone geometry, large (>1cm) femoral head cysts, limb-length discrepancy (> 2cm) and small prosthetic head size (less than 50mm for men and less than 46mm for women) are risk factors for hip resurfacing arthroplasty (HRA). Purpose. To present clinical and radiographic results of HRA in patients having risk factors. Patients and methods: A total of 39 HRA was inserted in 33 patients (11 men and 22 women). Birmingham hip resurfacing (Smith & Nephew, UK) was used in 9 hips and Adept (Finsbury, UK) was used in 30 hips. Among the 30 hips inserted Adept, 11 cups were fixed with rim screws. The mean age of the patients at the time of operation was 52 years. The mean weight and height of the male and female patients were 70.4kg and 167cm, 58.5kg and 154.4cm, respectively. The median head size of the male and female patients was 50mm and 42mm, respectively. Preoperative diagnosis was primary osteoarthritis in 6 hips and secondary osteoarthritis due to aceatbular dysplasia (DDH) in 33 hips. Risk factors of HRA were listed for each patient. The Harris hip score and visual analogue pain scale (VAS) were measures of clinical outcome. Radiographic review was performed retrospectively. MRI and CT images were acquired in 29 hips and 2 hips, respectively, at a mean of 4.8 years after HRA to find periprosthetic soft tissue abnormality such as a psedotumor. Kaplan-Meier method was used to calculate implant survivorship. Results. Two hips had no risk factor, whereas 37 hips had at least one risk factor. Risk factors were listed as follows: female gender in 27, old age in nine, severe acetabular dysplasia in 25, poor proximal femoral bone geometry in 11, head cysts in 13, limb-length discrepancy in three and small head size in 21. There were two revisions in two men. One hip was revised because of acute infection. The patient had a risk factor (old age). Another hip was revised because of cup loosening. The patient had two risk factors (severe acetabular dysplasia and small head size). The mean follow-up period for unrevised hips was 5 years (range, 2 to 8 years). The Harris hip score improved from 47.3 points preoperatively to 96.5 points at the latest follow-up (p<0.001). VAS improved from 65 preoperatively to 5 at the latest follow-up (p<0.001). Using revision for any reason as the endpoint, the Kaplan-Meier survivorship was 94.9% at 5years. No implant was loose at the latest radiographic examination. MRI and CT of the hip revealed no pseudotumor. Discussion. In this series, only two patients had no risk factor for HRA. Although majority of our patients were women with acetabular dysplasia and small head size, clinical and radiographic results of HRA were good up to five years (Figs 1 and 2: pre- and post-operative X-ray of 49y women having five risk factors). Conclusion. Clinical and radiographic results of HRA were good in patients who have risk factors

Introduction. We sought to determine the 10-year survivorship of single-radius, posterior-stabilized total knee arthroplasty (TKA) in Asian patients. We also aimed to determine whether the long-term clinical and radiographic results differed between patients with and without patellar resurfacing. Materials and Methods. This retrospective study included 148 (115 patients) consecutive single-radius, posterior-stabilized TKAs. Ten-year survivorship analysis was performed using the Kaplan-Meier method with additional surgery for any reason as the end-point. Furthermore, long-term clinical and radiographic results of 109 knees (74%; 84 patients) with more than a 10-year follow-up were analyzed. Ten-year survivorship and long-term outcomes after surgery were determined, and outcomes were compared between patients with and without patellar resurfacing. Results. Cumulative survival rate of the single-radius posterior-stabilized TKA of 148 knees was 97.7% (95% confidence interval, 93.1%–99.3%) at 10 years after surgery. Three knees had additional surgery during the 10-year follow-up because of one case of instability and two periprosthetic infections. Mean postoperative Knee Society knee score and function score were 97 and 75, respectively. There was no aseptic loosening of the prosthesis, even though a non-progressive radiolucent line was found in 10 (9%) knees. There were no differences in postoperative scores and degree of patellar tilt and displacement between patients with and without patellar resurfacing. Conclusions. Single-radius, posterior-stabilized TKA showed satisfactory long-term clinical and radiographic outcomes in Asian patients regardless of patellar resurfacing, with comparable survivorship to that reported in westerners

Background. The short stem prosthesis showed good results in patients with primary osteoarthritis. However, there were a few studies about the short stem THA in patients with osteonecrosis of the femoral head (ONFH). Objective. To evaluate the clinical and radiographic results of the short stem THA in patients with ONFH. The authors hypothesized that the short stem THA would be a promising procedure for patients with ONFH. Material and Method. The authors reviewed 120 osteonecrotic hips in 93 patients who underwent THA with Metha® short stem from November 2010 to February 2013. The appearance of bone trabeculae development and radiolucent line was reviewed using Gruen's classification. The Harris hip score (HHS) was recorded at 6, 12, 24 and 36 months postoperative for evaluating the clinical results. Results. The mean age of patients was 44.4 years (18–68) with the mean BMI of 22.7 (15.1–32.5, SD 3.5). The average follow-up period was 29.2 months (20–47). The mean HHS was significantly improved from 43.9 (22.7–74, SD 7.7) preoperatively to 97.7 (85.9–100, SD 2.7) at 6 months postoperatively (p<0.01). The radiographic change around the stems showed bone trabeculae development at zone 1 (77 cases)(64.2%), 2 (27 cases)(22.5%), 3 (106 cases)(88.3%), 6 (120 cases)(100%) and 7 (115 cases)(95.8%). There was 1 case (0.8%) of 5 mm subsidence and the radiolucent line was observed in zone 1. There were 6 cases (5%) of intraoperative femoral fractures and were treated with cerclage wires, no further subsidence was observed. There was 1 case (0.8%) of distal stem perforation which had stable bone ingrowth. No revision was required. Conclusion. The clinical and radiographic results of the short stem THA in patients with ONFH are generally satisfactory. Its design enables preservation of the bone stock and the bone trabeculae appear to confirm the assumption of proximal force transmission. The authors believe that the short stem THA is a promising procedure for patients with ONFH

Introduction. The decreased bone mass or local osteoporosis at the proximal femur is often recognized in patients of rheumatoid arthritis (RA). In total hip arthroplasty (THA), the cancellous bone will be lost when rasping technique is applied for the preparation of stem insertion. In addition, cutting or elongation for contracted muscles around the hip joint can be required to insert the stem. To avoid these problems, the non-broaching, non-rasping impaction technique for the stems was applied in THA for the patients with RA. We report clinical and radiographic results of this method. Materials and Methods. In surgery, the femoral neck was cut and prepared without using a box chisel, reamer or broaches, instead, a series of trial stems were used with the method of impaction technique. After impaction of cancellous bone with the final size of the trial stem, the stem is fixed by bone cement without taking any cement mantle. Full weight bearing was allowed for all patients from the next day of the surgery. We investigated short-term clinical and radiographic results and the incidence of complication that was related to this technique. Post-operative radiological results with the minimum follow-up of 12 months after surgery were analyzed in 31 joints (25 cases) with this technique. The mean age at the time of surgery was 66.3 years (46∼82). The mean duration after surgery was 62 months (14∼108). Results. No case showed hypotension, decrease of saturation of oxygen concentration during this technique in surgery. Neither pulmonary embolism nor venous thrombosis of the leg was recognized in those cases. All cases showed good walking performance and did not show any hip and thigh pain at the time of follow up. The preoperative mean HHS score was 32.7 (±12.1) and improved to 79.4 (±11.7) at the time of follow up. Although two cases showed slight subsidence of the stem, no case showed the development of the loosening or any adverse effect such as radiolucent line, breakage of the bone cement, and any migration around the stem at the time of follow up. Conclusion. Although the number of our cases is small and also the follow up period is short, the non-broaching, non-rasping impaction method for stem in THA is thought to be better technique to preserve cancellous bone of the proximal femur, to avoid cutting or elongation of muscles around the hip joint, and to obtain good implant fixation for the patients with osteoporotic proximal femur

Total hip arthroplasty (THA) is frequently performed as a salvage procedure for the acetabular fracture when posttraumatic osteoarthritis, posttraumatic avascular necrosis, or fixation failure with subluxation develop. Special considerations for this situation include previous surgical exposure with dense scar tissue, the type and location of implants, the location and amount of heterotopic ossification, indolent infection, previous sciatic nerve palsy, and the pathoanatomy of existing acetabular defect. These factors can influence the choice of surgical exposure and the reconstructive method. The outcomes of THA after acetabular fracture are generally less favorable than those of the nontraumatic degenerative arthritis. Reason for this high failure is the low mean age and the high activity level of the patient. Other important reasons for failure include the problem of acetabular bone deficiency and compromised bone quality. We evaluated the results of cementless THA in patient who had previous acetabular fracture. We also compared this result with those of patients with posttraumatic avascular necrosis of the femoral head. Forty-five consecutive cementless THAs were performed for the treatment of post-traumatic osteoarthritis after acetabular fracture between December 1993 and December 2008. Of these patients, 15 patients were died or lost to follow-up monitoring before the end of the minimum one year follow-up period. This left 30 patients (30 hips) as the subjects of our retrospective review. We evaluated the clinical and radiographic results of these patients and compared with the results of THA in patients with post-traumatic AVN of the femoral head which had without acetabular damage. Two hips required revision of the cup secondary to early migration of the acetabular cup (1 hip) and postoperative deep infection (1 hip). There was no significant difference in clinical and radiographic results between two groups except implanted acetabular component size and required bone graft (p<0.05). The Kaplan-Meier ten-year survival rate, with revision as the end-point, was 90% and 96.7% with loosening of acetabular component as the end-point. Our series suggested that compared with cemented components, uncemented sockets may improve the results of arthroplasty after previous acetabular fracture. In conclusion, cementless THA following acetabular fracture presents unique challenge to the surgeon, careful preoperative assessment and secure component fixation with proper bone grafting is essential to minimize problems

Introduction. Total knee arthroplasty is a highly effective procedure to improve the quality of life in patients with advanced osteoarthritis. The number of these procedures are expected to grow 174% by 2030. This growth rate is expected to economically strain the health care system. A potential solution to alleviate this problem is the utilization of single use instruments (SUI). Potential advantages of SUI include: improved operating room efficiencies, decreased costs associated with traditional instrument management (sterile processing, shipping), and decreased infection risk. The present study examines the clinical results of SUI compared to standard instrumentation. Furthermore, economic modeling is performed to examine the cost savings that is potentially realized with their use. Materials and Methods. 51 patients receiving a TKA with use of SUI were prospectively compared to 49 patients utilizing standard instrumentation. Knee Society Scores and Radiographic alignment will be evaluated. Adverse events will be recorded. Economic modeling of SUI will be performed in 4 different areas: 1. Decreased infection burden; 2. Operating room logistics; 3. Sterile processing savings; and 4. Instrument logistical savings. Results. The average Pre-operative KSS (Objective/Functional) scores were 48.7/41.6 for the SIU patients compared to 50.2/38.7 for the standard instrumentation patients. Post-operative improvements measured 84.0/72.8 and 83.9/76.4 for the 2 groups respectively. The Pre-operative Hip-Knee-Ankle Angle was 176.2 and 177.0 for the 2 groups. The SUI HKA improved to 179.3 while the standard improved to 178.9. There were no statistical differences between the 2 groups. Furthermore, there were no cases of subsidence, migration, loosening, or infection in either group. There were no SUI procedure abandonments. Economic analysis revealed a decreased risk of Infection burden of $28.08/case. Operating room efficiencies include reduced set-up/take-down time and case efficiency savings/case. This averages $348.14/case. Instrument sterilization savings occur by bypassing the central sterile-processing department completely and models to $700/case. Finally, instrument logistics savings include time and money spent organizing/turning over/shipping instrument sets for cases. This estimate is $112.88/case for a total economic value of $1, 189.10/case. Discussion. In summary, the present study confirms that SUI provides similar clinical and radiographic results to standard instrumentation for TKA. Furthermore, SUI offers significant cost savings/case via potential benefits of reduced risk of infection, increased operating room productivity, and significant tray sterilization and loaner instrumentation cost savings

Introduction. Cementless Total Knee Replacement (TKR) was introduced to improve the longevity of implant; but has yet to be widely adopted because of reports of higher earlier failures in some series. The cementless TKR design has evolved recently and we have been using cementless component – both femoral and tibial on our patients. The long follow-up for fully TKR has been scarce in the literature. The purpose of this study isto investigate the minimum of ten years clinical and radiographic result of cementless titanium component and cementless tantalum component in primary TKR. Material & method. From 2008 to 2010 317 TKR underwent primary total knee with cementless femoral component titanium based (Zimmer Nexgen) and cementless tantalum component monoblock tibial component, The surgery was performed mainly on younger patients - average age was 48 yrs old ranging from 26 yrs old to 62 yrs old. All surgeries were performed by single surgeon. All patients were followed clinically and radiographically for a minimum of 8 yrs. Mean 7.8 years and range from 7 to 9 years. The underlying diagnosis for majority of the cases were degenerative arthritis in 97 of the cases and rheumatoid arthritis on the 3%. Result. We have revised 6 cases − 3 cases were for sepsis. They were revised in 2 stages. And we also revised 5 cases for loosening of femoral component. The tibial component revision for aseptic loosening or osteolysis for an end point for survivorship was a 100% for the tibia monoblock design. There was no radiographic evidence of tibial component loosening or subsidence, or migration at the time of the latest follow-up for tibia monoblock. On the femoral part we documented 16 cases other than those 4 revision for osteolysis, where limited osteolysis happened in some area of the tibial component but it did not affect stability and those has been followed up for a longer term. There was interesting phenomena in some of those cases where bone growth happened around the anterior cortex where it sealed the component entirely. Knee society scores improved from 51 pre-operatively to 94 pre-operatively on the last clinical visit. We had 32 cases where the patientswere able to regain their full mobility flexion of over 150 degrees. Conclusion. Our data clearly shows that the cementless TKR has excellent result as compared to the cemented with a good survival ship at 10 years. The tantalum tibial component shows an excellent survivorship. The femoral component also present reasonably good result but we still faced a few cases of loosening. The functional outcome for the implant with the surgery was satisfactory. With this result we strongly recommend using the cementless implant in young patients. We believe that cementless tibial is totally safe at this point as well as the femoral cementless prosthesis. However, we expect some improvement with the outcome with the femoral component when using the tantalum

Purpose. Two-stage revision with the removal of all prosthesis has been considered to be the gold standard for treatment of periprosthetic joint infection. However, removal of well-fixed femoral stem is technically challenging and may cause excessive bone loss. The aim of this study was to compare the results between retention and removal of femoral stem when performing two-stage revision total hip arthroplasty for periprosthetic joint infection. Materials & Methods. From 2007 to 2014, ninety-four patients with infection after hip arthroplasty were treated by using two-stage exchange protocol with temporary articulating spacers. Among them, 38 patients completed the planned second stage reimplantation. Stem was exchanged in 15 patients (group I) and retained in 23 patients (group II). We retrospectively investigated the clinical and radiographic results after an average 39.9 months follow up. Results. The rate of infection control was 86.6% (13/15) in group I, 86.9% (20/23) in group II. There were no statistical differences between the two groups in term of demographics or presence of resistant organism. Conclusion. Retention of well-fixed cementless stem during two-stage revision total hip arthroplasty could be alternative treatment option for the treatment of periprosthetic joint infection

Hypothesis. The Synergy femoral component was introduced in 1996 as a second generation titanium proximally porous-coated tapered stem with dual offsets to help better restore femoral offset at THR. The purpose of this prospective study was to evaluate the long-term (minimum 10 year) clinical and radiographic results and survivorship of this femoral component at our institution. Methods & Analysis. From 1996 to 1999, 256 cementless Synergy femoral components were inserted and followed prospectively in 254 patients requiring THR. 185 were standard offset stems (72.3%) while 71 stems (27.7%) were high offset. The average follow-up was 11.2 years (range 10.0 to 12.9 years). Average age at index THR was 58.9 year. Two hundred and eight stems had standard porous coating while 48 had additional HA coating. Fifty-two cases were either lost to follow-up or had died prior to 10 years follow-up. Patients were followed prospectively using validated clinical outcome scores and radiographs. Kaplan-Meier survival analysis was performed. Results. All health-related outcomes were significantly improved from pre-operative with a mean Harris Hip score and WOMAC at last follow-up of 91.6 and 81.8, respectively. From the initial 256 femoral stems inserted, only 5 stems have been revised. Two stems have been revised for infection. Only one stem has been revised due to subsidence at nine months, likely as a result of a calcar fracture at the index THR. Two stems were revised for peri-prosthetic fracture as a result of patient falls. Radiographic review of remaining stems in situ identified no cases of loosening. Kaplan-Meier survivorship analysis of the femoral component, with revision for aseptic loosening, was 99.2% at 12 years. Conclusion. The Synergy femoral component, a second generation titanium proximally porous-coated tapered stem design with dual offsets, has demonstrated excellent clinical and radiographic results and long-term survivorship (99% at 10 years) at our institution

Introduction. Although total knee arthroplasty (TKA) in end-stage hemophilic arthropathy can reduce the severe joint pain and improve the functional disability, it is technically demanding. In addition, it has generally reported a high rate of complication including periprosthetic joint infection (PJI) and component loosening up to 20%. Although the Knee Society classification system of TKA complication was introduced, the complications of TKA in hemophilic arthropathy has not stratified using this classification system in previous articles to the best of our knowledge. The purpose of this study was to evaluate the mid-term outcomes and complications of TKA in hemophilic arthropathy. Methods. The study retrospectively reviewed 131 consecutive primary TKAs (102 patients) in single institute. The mean patient age was 41.0 years and mean follow-up time was 6.4 years. The clinical and radiographic results were evaluated. The complications were categorized according to the classification system of the Knee Society for TKA complications. Results. The average WOMAC score improved from 66.0 to 24.2. The average flexion contracture significantly decreased from 17.3° to 4.7°, but the average pre and postoperative maximum flexion did not differ (80.9 ° vs. 85.6°). The average mechanical axis was varus 5.2° preoperatively and valgus 0.3° postoperatively. The coronal position of femoral and tibial components and sagittal position of those components were within ±3° in 83.2%, 89.3%, 63.4%, and 73.3%. The complications occurred in 17 knees (13.0%). There were 7 bleeding and hemarthrosis. Five knees were treated with increased amounts of coagulation factor concentrate and two knees were treated with incision and drainage of hematoma. One medial collateral ligament injury of grade 2 required change of postoperative rehabilitation protocol and bracing. Two stiffness of grade 3 required unplanned admission and manipulation under anesthesia. Three deep PJI were treated with 2 stage revision TKA. There were 4 periprosthetic fractures. Three distal femur fractures were treated with open reduction and internal fixation for 3 knees. One patellar fracture was healed with conservative treatment. Conclusions. The mid-term results of TKA in end-stage hemophilic arthropathy were satisfactory with obtaining pain relief, improving function, and decreasing flexion contracture. Bleeding and PJI continues to be a major concern for TKA in patients with hemophilic arthropathy, and risk of periprosthetic fracture has to be taken into account for patient education and appropriate prevention. Level of evidence. Level IV

Aim. Femoral or tibial massive bone defects (AORI F2B-F3 / T2B-T3) are common in septic total knee replacement. Different surgical techniques are described in literature. In our study we show clinical and radiological results associated with the use of tantalum metaphyseal cones in the management of cavitary bone defects in two-stage complex knee revision. Method. Since 2010 we have implanted 70 tantalum metaphyseal cones associated with constrained or semiconstrained knee prostheses in 47 patients. The indication for revision was periprosthetic knee infection (43 cases, 91.5%) or septic knee arthritis (4 patients, 8.5%) with massive bone defect. All cases underwent a two-stage procedure. Patients were screened for main demographic and surgical data. Clinical and radiological analysis was performed in the preoperative and at 3,6 months, 1 years and each year thereafter in the postoperative. The mean follow-up was 31.1 months ± 18.8. No dropout was observed. Results. Objective and subjective functional scores (KSS, OKS) showed a statistically significant improvement from the preoperative to last follow-up (p <0.001). All cones but one (98.6%) showed radiological osteointegration. We did not find any cone-related intraoperative or postoperative mechanical complication with a 100% survival rate when we consider aseptic loosening as cause of revision. Six non progressive radiolucencies were observed. Two septic failures (4.3%) with implant and cone removal were reported. Conclusions. The ideal treatment for cavitary bone defects in two-stage TKA septic revision is still unclear. The use of metaphyseal tantalum cones showed excellent clinical and radiographic results with a low rate of related complications. The main finding of our study is the cone-related infection rate (2.9%) in this particular series of patients. This data is comparable or better than other previous report about this topic with unhomogeneous cohort of patients

Cementless femoral stems of many designs now provide dependable long-term fixation and excellent, near normal function in patients of all ages, sexes and level of activity. However, a number of issues related to cementless stem fixation could be further improved: Optimization of load transfer to proximal femur to minimise fracture risk and maximise bone preservation; Elimination of proximal-distal mismatch concerns, including bowed femurs; Facilitation of femoral stem insertion, especially for Anterior and MIS exposures; Facilitation of revision with implants capable of providing durable fixation for active patients. The potential benefits of short stem femoral THA implants include: Ease of insertion; Reproducibility of insertion; Avoidance of issues related to proximal-distal anatomic mismatch or variations in proximal femoral diaphyseal anatomy (e.g. femoral bowing); Facilitation of MIS surgical approaches, especially anterior exposures; Optimization of proximal femoral load transfer with consequent maximization of proximal bone preservation. The purpose of this presentation is to describe the design rationale and characteristics of short (< 120 mm) uncemented primary THA femoral stems and to evaluate the clinical and radiographic results of short stems. Outcome results extending beyond 10 years support the proposition that short stems of appropriate design provide dependable long-term fixation and equivalent clinical results to those currently achievable with cementless stems of conventional length in patients of all ages, sexes and level of activity

Purpose. The fourth generation ceramic, in which zirconia is incorporated into the alumina matrix, was developed to reduce the risk of ceramic fractures. The purpose of this study was to evaluate the survivorship, clinical and radiographic results, and bearing-related failures associated with total hip arthroplasty using zirconia-toughened alumina ceramic-on-ceramic bearings over a minimum follow-up of 5 years. Materials and methods. We retrospectively analysed 135 patients (151 hips) who underwent cementless total hip arthroplasty using zirconia-toughened alumina ceramic-on-ceramic bearings. There were 58 men and 77 women with mean age of 55.9 years (range, 20 to 82 years) at index surgery. Acetabular and femoral components were cementless in all hips. A 36 mm head was used in 81 of 151 hips and a 32 mm head was used in 70 hips with smaller acetabular shells. The mean duration of follow-up was 6.1 years (range, 5 to 6.8 years). Results. Kaplan-Meier survival analysis with an end point of revision for any reason was 100% at 6.8 years. All acetabular and femoral components showed bony ingrowth. No radiographic evidence of osteolysis was identified. No ceramic fracture occurred. There were 4 (2.6%) noisy hips (1 squeaking and 3 clickings), but no patient could reproduce the noise and required revision. Other complications included one iliopsoas tendonitis and one dislocation. Conclusions. The minimum 5-year results of total hip arthroplasties performed using 32 mm or 36 mm zirconia-toughened alumina ceramic-on-ceramic bearings were encouraging with excellent survivorship. However, it was also found that the risk of noise development remains even for the newest generation of ceramics

Introduction: Although volumetric wear reduction has been demonstrated in knee simulator studies, there is no long-term in-vivo evidence supporting wear reduction and durability with uni-directional rotating platform PS design. This design was introduced to reduced spin-out and provide greater range of motion. This is the first long-term report of this implant, a prospective study investigating clinical and radiographic survivorship with 10 years follow-up. Material and Methods: Between January 2000 to March 2001, 118 consecutive patients (141 knees) received cemented RP TKRs. All patients were followed prospectively using clinical and radiographic criteria as defined by the Knee Society. At minimum nine years follow-up 20 patients were deceased, 11 were lost to follow-up and two refused to participate in the study, leaving 85 patients (100 knees) for final analysis. Results: Good to excellent results were achieved in 95% of patients. There were no cases of malalignment, spinout, aseptic loosening or osteolysis. The mean ROM improved from 111.2 ± 15.2 degrees to 119 ± 3.8 degrees. The mean WOMAC score was 30 ± 14, KSS scores improved from an average of 48 to 96. Sporting activities such as golf, tennis and walking was 29%, 12% and 32%, respectively. Anterior knee pain was present in 15% of cases. The incidence of asymptomatic crepitation and painful crepitation requiring scar excision was 10% and 4% respectively. During this period we had one case of infection and one revision for fracture. Kaplan-Meier survivorship at 10 years for mechanical failure and failure for all failures was 100% and 95.7%, respectively. Discussion and Conclusion: Ten-year follow-up of RP-PS design demonstrates excellent clinical and radiographic results with no failures for mechanical reasons. There were no spin-out and average ROM was 119 ± 3.8 degrees

A prospective case control study analysed clinical and radiographic results in patients operated on with the periosteum autologous chondrocyte implantation (ACI) due to cartilage lesions on the femoral condyles over 10 years ago. 31 out of the 45 patients (3 failures, 9 non-responders, 2 others) were available for a continuous clinical (Lyshom/Tegner, IKDC, KOOS) and radiographic (Kellgren-Lawrence) follow-up at 0, 2, 5, and 10 years after the ACI procedure. The patients were sub-grouped into focal cartilage lesions (FL) – 10, osteochondritis dissecans (OCD) – 12, and cartilage lesions with simultaneous ACL reconstruction (ACL) – 9 subgroups. Lysholm, Tegner, and IKCD subjective scores revealed stable results over the period from 2 to 10 years with a significant improvement toward the pre-operative levels, but the patients had not reached their pre-injury Tegner levels. KOOS profile at 10 years was: Pain 78.6, Symptoms 78.1, Activities of daily living 82.5, Sports 56.9, and Quality of life 55.1. A 10-year IKDC knee examination classified operated knees as: 14 normal, 10 nearly normal, 5 abnormal and 2 severely abnormal. Kellgren-Lawrence scores of 2 and above were found in 10 patients (FL 5, OCD 0, and ACL 5). Seven patients in the group required an arthroscopic re-intervention (3 ACI related, 4 ACI unrelated). ACI provided safe and stable performance of operated knees over ten years. High incidence of knee osteoarthritis in FL and ACL subgroups, and low incidence in OCD patients indicate that best long performance is expected in localised low-impact cartilage lesions of young patients

Background. The purpose of this study is to report the outcome of navigation-assisted cruciate-retaining total knee arthroplasty (TKA) using one type of cemented, second-generation, floating-platform (FP), mobile-bearing system. Methods. We retrospectively reviewed 42 patients (51 knees) who underwent cruciate retaining TKAs using e.motion-FP prostheses under navigational guidance. The preoperative diagnosis was osteoarthritis in all knees except one rheumatoid arthritis. There were 2 men (2 knees) and 40 women (49 knees) with a mean age of 64.0 ± 4.7 years (range, 51 – 76 years) at the time of index surgery. The mean follow-up was 120.0 months (range, 106 – 126 months). Clinical and radiographic results as well as mechanical survival rate of this type prosthesis were investigated at a mean follow-up of 10 years. Results. The mean mechanical femorotibial angle was improved from 11.7° ± 3.3° (range, 5.0° to 19.7°) preoperatively to 1.4° ± 1.7° (range, −2.9° to 6.4°) at the latest follow-up. No prosthesis-related complications such as bearing dislocation or breakage occurred and no knees showed aseptic loosening or progressive osteolysis. Kaplan-Meier survivorship at 10.5 years was 100% with an endpoint of revision for any prosthesis-associated reason. Conclusions. The emotion-floating platform mobile-bearing design yielded satisfactory mid-term durability and implant performance under navigational guidance