The concept of stainless steel dual mobility cups in total hip arthroplasty has demonstrated very low long-term instability rates and a 98% survival rate after 12 years. We systematically implanted titanium alloy acetabular cups during a one year period. The purpose of our retrospective study was to report the 18-year clinical outcome data in a homogeneous and continuous series of 103 primary total hip replacements after implantation of a cementless titanium cup. All patients were implanted with NOVAE Ti (SERF) cups made of titanium alloy combined with a retentive polyethylene liner and a 22.2 mm cobalt chrome prosthetic head. Mean patient age at the time of surgery was 53 years. All patients were clinically and radiographically evaluated. The overall 18-year actuarial cup survival rate with a 95% confidence interval was 87.4%. At last follow-up, there was no evidence of implant instability whereas acetabular aseptic loosening was reported in one case and high wear of the retentive liner in 9. The results of this investigation confirmed the long-term stability of dual-mobility implants. The main limitation of this system was early wear of the polyethylene liner in contact with the titanium metal back and reaction with third body along with loss of liner retentivity. In our study, titanium demonstrated favourable osteointegration properties but poor tribologic characteristics, therefore suggesting its interest at the bone-cup interface only