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The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 7 | Pages 1019 - 1023
1 Jul 2005
Shimogaki K Yasunaga Y Ochi M

Acetabular dysplasia was produced in 24 immature white rabbits. A rotational acetabular osteotomy was then carried out and radiological and histological studies of the articular cartilage were made. In the hips which did not undergo osteotomy, radiographs at 26 weeks showed that residual subluxation remained and arthritic changes such as narrowing of the joint space or dislocation were still seen. However, in the operated group there was a remarkable increase in cover, but arthritic changes were not observed. After 24 weeks, the Mankin grading score in the operated group was significantly lower than that in the non-operated group. The latter hips showed an irregular surface of the cartilage, exfoliation and proliferation of synovial tissue. In those undergoing osteotomy, primary cloning of chondrocytes or hypercellularity was seen and at 24 weeks after operation and metaplasia of the cartilage in the fibrous tissue was observed in the boundary between the medial area of the acetabulum and the acetabular fossa


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_4 | Pages 11 - 11
1 Apr 2018
Kwong L Billi F Keller S Kavanaugh A Luu A Ward J Salinas C Paprosky W
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Introduction. The objective of this study was to compare the performance of the Explant Acetabular Cup Removal System (Zimmer), which has been the favored system for many surgeons during hip revision surgery, and the new EZout Powered Acetabular Revision System (Stryker). Methods. 54mm Stryker Trident® acetabular shells were inserted into the foam acetabula of 24 composite hemi-pelvises (Sawbones). The hemi-pelvises were mounted on a supporting apparatus enclosing three load cells. Strain gauges were placed on the hemipelvis, on the posterior and the anterior wall, and on the internal ischium in proximity to the acetabular fossa. A thermocouple was fixed onto the polar region of the acetabular component. One experienced orthopaedic surgeon and one resident performed mock revision surgery 6 times each per system. Results. Statistical analysis was conducted using Tukey's range test (HSD). The maximum force transferred to the implant was more than 4X lower with the EZout System regardless the surgeon experience (p=1.0E-08). Overall, recorded strains were lower for the EZout System with the higher decrease in strain (5X) observed at the posterior wall region(p=2E-08). The temperature at the interface was higher for the EZout System but never more than 37°C. Total removal time was on average reduced by a third with the EZout System (p=0.01). The calculated torque was lower for the EZout System. The amount of foam left on the cup after removal, which mimics the compromised bone, was 2.5X higher on average for the Explant System with most of the foam concentrated in the polar region. Lastly, it was observed that the polar region of each implant was reached by rotating the EZout System handpiece within a very narrow cylinder of space centered along the axis of the acetabular component compared to the Explant System, which required movement of the pivoting osteotomes within a large cone-shaped operating envelope. Discussion. Quantitatively, the EZout System required lower force, producing lower strains in the surrounding composite bone. Higher impact forces and associated increased strains may increase fracture risk. Qualitatively, the Explant System required a greater cone of movement than the EZout System requiring more space for the surgeon to leverage the handle of the tool. In addition, both surgeon and resident felt substantially greater exhaustion after using the Explant System vs. the EZout System. The resident compensated for the increased workload of the Explant with time, the experienced surgeon with force. The learning curve for both experienced surgeon and resident was also much shorter with the EZout System as shown by the close force values between the experienced surgeon and resident. Conclusion. Based on the results of this in vitro model, the EZout Powered Acetabular Removal System may be a reasonable alternative to manual removal techniques


Bone & Joint Research
Vol. 4, Issue 4 | Pages 50 - 55
1 Apr 2015
Sekimoto T Kurogi S Funamoto T Ota T Watanabe S Sakamoto T Hamada H Chosa E

Objectives

Excessive acetabular coverage is the most common cause of pincer-type femoroacetabular impingement. To date, an association between acetabular over-coverage and genetic variations has not been studied. In this study we investigated the association between single nucleotide polymorphisms (SNPs) of paralogous Homeobox (HOX)9 genes and acetabular coverage in Japanese individuals to identify a possible genetic variation associated with acetabular over-coverage.

Methods

We investigated 19 total SNPs in the four HOX9 paralogs, then focused in detail on seven of those located in the 3’ untranslated region of HOXB9 (rs8844, rs3826541, rs3826540, rs7405887, rs2303485, rs2303486, rs79931349) using a case-control association study. The seven HOXB9 SNPs were genotyped in 316 subjects who had all undergone radiological examination. The association study was performed by both single-locus and haplotype-based analyses.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 7 | Pages 1012 - 1018
1 Jul 2005
Beck M Kalhor M Leunig M Ganz R

Recently, femoroacetabular impingement has been recognised as a cause of early osteoarthritis. There are two mechanisms of impingement: 1) cam impingement caused by a non-spherical head and 2) pincer impingement caused by excessive acetabular cover. We hypothesised that both mechanisms result in different patterns of articular damage. Of 302 analysed hips only 26 had an isolated cam and 16 an isolated pincer impingement. Cam impingement caused damage to the anterosuperior acetabular cartilage with separation between the labrum and cartilage. During flexion, the cartilage was sheared off the bone by the non-spherical femoral head while the labrum remained untouched. In pincer impingement, the cartilage damage was located circumferentially and included only a narrow strip. During movement the labrum is crushed between the acetabular rim and the femoral neck causing degeneration and ossification.

Both cam and pincer impingement lead to osteoarthritis of the hip. Labral damage indicates ongoing impingement and rarely occurs alone.