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Bone & Joint Research
Vol. 13, Issue 8 | Pages 401 - 410
15 Aug 2024
Hu H Ding H Lyu J Chen Y Huang C Zhang C Li W Fang X Zhang W

Aims

This aim of this study was to analyze the detection rate of rare pathogens in bone and joint infections (BJIs) using metagenomic next-generation sequencing (mNGS), and the impact of mNGS on clinical diagnosis and treatment.

Methods

A retrospective analysis was conducted on 235 patients with BJIs who were treated at our hospital between January 2015 and December 2021. Patients were divided into the no-mNGS group (microbial culture only) and the mNGS group (mNGS testing and microbial culture) based on whether mNGS testing was used or not.


The Bone & Joint Journal
Vol. 102-B, Issue 9 | Pages 1210 - 1218
14 Sep 2020
Zhang H Guan L Hai Y Liu Y Ding H Chen X

Aims

The aim of this study was to use diffusion tensor imaging (DTI) to investigate changes in diffusion metrics in patients with cervical spondylotic myelopathy (CSM) up to five years after decompressive surgery. We correlated these changes with clinical outcomes as scored by the Modified Japanese Orthopedic Association (mJOA) method, Neck Disability Index (NDI), and Visual Analogue Scale (VAS).

Methods

We used multi-shot, high-resolution, diffusion tensor imaging (ms-DTI) in patients with cervical spondylotic myelopathy (CSM) to investigate the change in diffusion metrics and clinical outcomes up to five years after anterior cervical interbody discectomy and fusion (ACDF). High signal intensity was identified on T2-weighted imaging, along with DTI metrics such as fractional anisotropy (FA). MJOA, NDI, and VAS scores were also collected and compared at each follow-up point. Spearman correlations identified correspondence between FA and clinical outcome scores.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 112 - 112
1 May 2016
Ding H Zhou J
Full Access

The aim was to identify the acetabular center, fix the acetabular implant, and reconstruct the hip rotation center using the residual Harris fossa and acetabular notch as anatomical markers during revision hip arthroplasty. Osteolysis is commonly found in the acetabulum during hip arthroplasty revision. It causes extensive defects and malformation of the anatomical structure, making correct fixation of a hip prosthesis difficult. We studied the relations of the anatomical positions between the Harris fossa and acetabular notch and the acetabular center (Fig. 1). Vertical distance from the hip rotation center to the teardrop connection and horizontal distance from the hip rotation center to the teardrop were measured on preoperative and postoperative radiographs. Vertical distance increased from 14.22±3.39 mm preoperatively to 32.64±4.51 mm postoperatively (t=3.65, P<0.05) and the horizontal distance from 25.13±3.46 mm to 32.87±4.73 mm (t=2.72, P<0.05). Altogether, 28 patients underwent revision hip arthroplasty based on the Paprosky classification for bone loss. The anatomical hip center was identified using the residual Harris fossa and acetabular notch as anatomical markers during revision hip arthroplasty. Based on these relations, we were able to place the hip prosthesis correctly. After surgery, restoration of the anatomical hip center was accomplished based on data obtained from radiographs(Fig.2 and Fig.3).